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PE20141722A1 - Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t - Google Patents

Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t

Info

Publication number
PE20141722A1
PE20141722A1 PE2014001134A PE2014001134A PE20141722A1 PE 20141722 A1 PE20141722 A1 PE 20141722A1 PE 2014001134 A PE2014001134 A PE 2014001134A PE 2014001134 A PE2014001134 A PE 2014001134A PE 20141722 A1 PE20141722 A1 PE 20141722A1
Authority
PE
Peru
Prior art keywords
hvr
seq
antibodies
improve
cell function
Prior art date
Application number
PE2014001134A
Other languages
English (en)
Inventor
Bryan Irving
Jeanne Cheung
Henry Chiu
Sophie M Lehar
Heather Maecker
Sanjeev Mariathasan
Yan Wu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42097246&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20141722(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PE20141722A1 publication Critical patent/PE20141722A1/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
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    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE REFIERE A UN ANTICUERPO ANTI-PD-L1 AISLADO, QUE PRESENTA UNA REGION VARIABLE DE CADENA PESADA QUE COMPRENDE UNA SECUENCIA HVR-H1 QUE ES SEQ ID NO:1, HVR-H2 QUE ES SEQ ID NO: 2, HVR-H3 QUE ES SEQ ID NO: 3; Y QUE SE COMBINA CON UNA CADENA LIGERA DE REGION VARIABLE QUE COMPRENDE UNA HVR-L1 QUE ES SEQ ID NO: 8, HVR-L2 QUE ES SEQ ID NO: 9, LA SECUENCIA HVR-L3 QUE ES SEQ ID N:10. SE REFIERE TAMBIEN A UN PROCESO PARA PRODUCIR DICHO ANTICUERPO, SIENDO UTIL PARA EL TRATAMIENTO DE TRASTORNOS DISFUNCIONALES DE LA CELULA T.
PE2014001134A 2008-12-09 2009-12-08 Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t PE20141722A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12109208P 2008-12-09 2008-12-09

Publications (1)

Publication Number Publication Date
PE20141722A1 true PE20141722A1 (es) 2014-12-02

Family

ID=42097246

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2011001188A PE20120341A1 (es) 2008-12-09 2009-12-08 Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t
PE2014001134A PE20141722A1 (es) 2008-12-09 2009-12-08 Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2011001188A PE20120341A1 (es) 2008-12-09 2009-12-08 Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t

Country Status (41)

Country Link
US (11) US8217149B2 (es)
EP (8) EP4591881A3 (es)
JP (6) JP5681638B2 (es)
KR (10) KR20210060670A (es)
CN (4) CN114835812A (es)
AR (2) AR074563A1 (es)
AU (5) AU2009333580B2 (es)
BR (1) BRPI0917592B1 (es)
CA (2) CA2740806C (es)
CL (1) CL2011001382A1 (es)
CO (1) CO6390023A2 (es)
CR (2) CR20160570A (es)
CY (4) CY1118943T1 (es)
DK (3) DK4331604T5 (es)
EC (1) ECSP11011115A (es)
ES (3) ES3019734T3 (es)
FI (4) FI4209510T3 (es)
FR (3) FR17C1050I2 (es)
HK (1) HK1247621A1 (es)
HR (3) HRP20170908T1 (es)
HU (7) HUE034832T2 (es)
IL (4) IL213353A (es)
LT (6) LT2376535T (es)
LU (1) LUC00051I2 (es)
MA (1) MA32948B1 (es)
MX (3) MX2011005853A (es)
MY (1) MY188826A (es)
NL (1) NL300914I2 (es)
NO (3) NO2018006I1 (es)
NZ (2) NZ717213A (es)
PE (2) PE20120341A1 (es)
PL (3) PL2376535T3 (es)
PT (3) PT4331604T (es)
RU (2) RU2636023C2 (es)
SG (3) SG196798A1 (es)
SI (3) SI4209510T1 (es)
SM (3) SMT201700311T1 (es)
TW (8) TWI729512B (es)
UA (1) UA109108C2 (es)
WO (1) WO2010077634A1 (es)
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ECSP11011115A (es) 2011-07-29
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US20140065135A1 (en) 2014-03-06
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EP3447073A1 (en) 2019-02-27
UA109108C2 (uk) 2015-07-27
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FR17C1050I1 (es) 2018-01-12
TWI729512B (zh) 2021-06-01
PT4209510T (pt) 2024-04-02
TWI419705B (zh) 2013-12-21
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JP2017136085A (ja) 2017-08-10
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KR20220047668A (ko) 2022-04-18
MX356367B (es) 2018-05-25
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US20130045200A1 (en) 2013-02-21
LT4331604T (lt) 2025-05-12

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