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WO2001079237A3 - Haplotypes of the galr1 gene - Google Patents

Haplotypes of the galr1 gene Download PDF

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Publication number
WO2001079237A3
WO2001079237A3 PCT/US2001/012306 US0112306W WO0179237A3 WO 2001079237 A3 WO2001079237 A3 WO 2001079237A3 US 0112306 W US0112306 W US 0112306W WO 0179237 A3 WO0179237 A3 WO 0179237A3
Authority
WO
WIPO (PCT)
Prior art keywords
galr1
gene
haplotypes
disclosed
galr1 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/012306
Other languages
French (fr)
Other versions
WO2001079237A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
R Rex Denton
Krishnan Nandabalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001253531A priority Critical patent/AU2001253531A1/en
Publication of WO2001079237A2 publication Critical patent/WO2001079237A2/en
Publication of WO2001079237A3 publication Critical patent/WO2001079237A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel single nucleotide polymorphisms in the human galanin receptor (GALR1) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the GALR1 gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the GALR1 gene in an individual are also disclosed. Polynucleotides containing one or more of the GALR1 polymorphisms disclosed herein are also described.
PCT/US2001/012306 2000-04-14 2001-04-16 Haplotypes of the galr1 gene Ceased WO2001079237A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253531A AU2001253531A1 (en) 2000-04-14 2001-04-16 Haplotypes of the galr1 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19783800P 2000-04-14 2000-04-14
US60/197,838 2000-04-14

Publications (2)

Publication Number Publication Date
WO2001079237A2 WO2001079237A2 (en) 2001-10-25
WO2001079237A3 true WO2001079237A3 (en) 2002-03-21

Family

ID=22730943

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012306 Ceased WO2001079237A2 (en) 2000-04-14 2001-04-16 Haplotypes of the galr1 gene

Country Status (2)

Country Link
AU (1) AU2001253531A1 (en)
WO (1) WO2001079237A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005299771A1 (en) 2004-10-21 2006-05-04 High Point Pharmaceuticals, Llc Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580728A (en) * 1994-06-17 1996-12-03 Perlin; Mark W. Method and system for genotyping
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis
US5580728A (en) * 1994-06-17 1996-12-03 Perlin; Mark W. Method and system for genotyping

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HALUSHKA ET AL.: "Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis", NATURE GENETICS, vol. 22, July 1999 (1999-07-01), pages 239 - 247, XP002906054 *
JACOBY ET AL.: "Structural organization of the mouse and human GALR1 galanin receptor genes (GALnr and GALNR) and chromosomal localization of the mouse gene", GENOMICS, vol. 45, November 1997 (1997-11-01), pages 496 - 508, XP002906053 *
LORIMER ET AL.: "Cloning, chromosomal location and transcriptional regulation of the human galanin-1 receptor gene (GALN1R)", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 241, December 1997 (1997-12-01), pages 558 - 564, XP002906052 *

Also Published As

Publication number Publication date
WO2001079237A2 (en) 2001-10-25
AU2001253531A1 (en) 2001-10-30

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