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WO2001079219A3 - Haplotypes of the ache gene - Google Patents

Haplotypes of the ache gene Download PDF

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Publication number
WO2001079219A3
WO2001079219A3 PCT/US2001/011853 US0111853W WO0179219A3 WO 2001079219 A3 WO2001079219 A3 WO 2001079219A3 US 0111853 W US0111853 W US 0111853W WO 0179219 A3 WO0179219 A3 WO 0179219A3
Authority
WO
WIPO (PCT)
Prior art keywords
ache
gene
haplotypes
ache gene
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011853
Other languages
French (fr)
Other versions
WO2001079219A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
Beena Koshy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001255317A priority Critical patent/AU2001255317A1/en
Publication of WO2001079219A2 publication Critical patent/WO2001079219A2/en
Publication of WO2001079219A3 publication Critical patent/WO2001079219A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel single nucleotide polymorphisms in the human acetylcholinesterase (ACHE) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the ACHE gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the ACHE gene in an individual are also disclosed. Polynucleotides containing one or more of the ACHE polymorphisms disclosed herein are also described.
PCT/US2001/011853 2000-04-14 2001-04-11 Haplotypes of the ache gene Ceased WO2001079219A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255317A AU2001255317A1 (en) 2000-04-14 2001-04-11 Haplotypes of the ache gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19717300P 2000-04-14 2000-04-14
US60/197,173 2000-04-14

Publications (2)

Publication Number Publication Date
WO2001079219A2 WO2001079219A2 (en) 2001-10-25
WO2001079219A3 true WO2001079219A3 (en) 2002-03-14

Family

ID=22728342

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011853 Ceased WO2001079219A2 (en) 2000-04-14 2001-04-11 Haplotypes of the ache gene

Country Status (2)

Country Link
AU (1) AU2001255317A1 (en)
WO (1) WO2001079219A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110196322A (en) * 2018-02-27 2019-09-03 广东志道医药科技有限公司 Organophosphate and carbamate pesticide method for detecting residue and its test strips and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LI Y. ET AL.: "Gene structure of mammalian acetylcholinesterase", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, December 1991 (1991-12-01), pages 23083 - 23090, XP002906055 *
SHAPIRA M. ET AL.: "A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases", HUMAN MOLECULAR GENETICS, vol. 9, 2000, pages 1273 - 1281, XP002906056 *

Also Published As

Publication number Publication date
WO2001079219A2 (en) 2001-10-25
AU2001255317A1 (en) 2001-10-30

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