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WO2001077131A3 - Haplotypes of the bglap gene - Google Patents

Haplotypes of the bglap gene Download PDF

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Publication number
WO2001077131A3
WO2001077131A3 PCT/US2001/012010 US0112010W WO0177131A3 WO 2001077131 A3 WO2001077131 A3 WO 2001077131A3 US 0112010 W US0112010 W US 0112010W WO 0177131 A3 WO0177131 A3 WO 0177131A3
Authority
WO
WIPO (PCT)
Prior art keywords
bglap
gene
haplotypes
disclosed
bglap gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/012010
Other languages
French (fr)
Other versions
WO2001077131A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
Beena Koshy
Eileen Rounds
J Claiborne Stephens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001253429A priority Critical patent/AU2001253429A1/en
Publication of WO2001077131A2 publication Critical patent/WO2001077131A2/en
Publication of WO2001077131A3 publication Critical patent/WO2001077131A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel single nucleotide polymorphisms in the human bone gamma carboxyglutamate protein (BGLAP) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the BGLAP gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the BGLAP gene in an individual are also disclosed. Polynucleotides containing one or more of the BGLAP polymorphisms disclosed herein are also described.
PCT/US2001/012010 2000-04-11 2001-04-11 Haplotypes of the bglap gene Ceased WO2001077131A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253429A AU2001253429A1 (en) 2000-04-11 2001-04-11 Haplotypes of the bglap gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19584000P 2000-04-11 2000-04-11
US60/195,840 2000-04-11

Publications (2)

Publication Number Publication Date
WO2001077131A2 WO2001077131A2 (en) 2001-10-18
WO2001077131A3 true WO2001077131A3 (en) 2002-03-21

Family

ID=22723038

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012010 Ceased WO2001077131A2 (en) 2000-04-11 2001-04-11 Haplotypes of the bglap gene

Country Status (2)

Country Link
AU (1) AU2001253429A1 (en)
WO (1) WO2001077131A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8778034B2 (en) 2006-09-14 2014-07-15 Afton Chemical Corporation Biodegradable fuel performance additives
CN109957007A (en) * 2017-12-22 2019-07-02 深圳先进技术研究院 A metabolite polypeptide artificial antigen and antibody and application

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CELESTE ET AL.: "Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones", EMBO JOURNAL, vol. 5, no. 8, August 1986 (1986-08-01), pages 1885 - 1890, XP002906057 *
DATABASE GENBANK [online] NCI-CGAP; January 1999 (1999-01-01), "Homo sapiens cDNA clone 3' similar to osteocalcin precursor (human)", XP002906059, Database accession no. AA706592 *
DOHI ET AL.: "A novel polymorphism in the promoter region for the human osteocalcin gene: the possibility of a correlation with bone mineral density in postmenopausal Japanese women", JOURNAL OF BONE AND MINERAL RESEARCH, vol. 13, no. 10, October 1998 (1998-10-01), pages 1633 - 1639, XP002906058 *
SAMBROOK ET AL.: "Molecular cloning: A laboratory manual", 1989, COLD SPRING HARBOR LABORATORY PRESS, COLD SPRING HARBOR, XP002906060 *

Also Published As

Publication number Publication date
AU2001253429A1 (en) 2001-10-23
WO2001077131A2 (en) 2001-10-18

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