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WO2001077130A3 - Haplotypes of the apoa2 gene - Google Patents

Haplotypes of the apoa2 gene Download PDF

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Publication number
WO2001077130A3
WO2001077130A3 PCT/US2001/011854 US0111854W WO0177130A3 WO 2001077130 A3 WO2001077130 A3 WO 2001077130A3 US 0111854 W US0111854 W US 0111854W WO 0177130 A3 WO0177130 A3 WO 0177130A3
Authority
WO
WIPO (PCT)
Prior art keywords
apoa2
gene
haplotypes
disclosed
apoa2 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011854
Other languages
French (fr)
Other versions
WO2001077130A2 (en
Inventor
Anne Chew
Julie Y Choi
Beena Koshy
J Claiborne Stephens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001255318A priority Critical patent/AU2001255318A1/en
Publication of WO2001077130A2 publication Critical patent/WO2001077130A2/en
Publication of WO2001077130A3 publication Critical patent/WO2001077130A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel single nucleotide polymorphisms in the human apolipoprotein A-II (APOA2) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the APOA2 gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the APOA2 gene in an individual are also disclosed. Polynucleotides containing one or more of the APOA2 polymorphisms disclosed herein are also described.
PCT/US2001/011854 2000-04-11 2001-04-11 Haplotypes of the apoa2 gene Ceased WO2001077130A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255318A AU2001255318A1 (en) 2000-04-11 2001-04-11 Haplotypes of the apoa2 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19581700P 2000-04-11 2000-04-11
US60/195,817 2000-04-11

Publications (2)

Publication Number Publication Date
WO2001077130A2 WO2001077130A2 (en) 2001-10-18
WO2001077130A3 true WO2001077130A3 (en) 2002-03-21

Family

ID=22722935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011854 Ceased WO2001077130A2 (en) 2000-04-11 2001-04-11 Haplotypes of the apoa2 gene

Country Status (2)

Country Link
AU (1) AU2001255318A1 (en)
WO (1) WO2001077130A2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LACKNER ET AL.: "The human apolipoproteins A-II gene: complete nucleic acid sequence and genomic organization", NUCLEIC ACIDS RESEARCH, vol. 13, no. 12, 1985, XP002947120 *

Also Published As

Publication number Publication date
AU2001255318A1 (en) 2001-10-23
WO2001077130A2 (en) 2001-10-18

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