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WO2001079221A3 - Haplotypes of the il8rb gene - Google Patents

Haplotypes of the il8rb gene Download PDF

Info

Publication number
WO2001079221A3
WO2001079221A3 PCT/US2001/011942 US0111942W WO0179221A3 WO 2001079221 A3 WO2001079221 A3 WO 2001079221A3 US 0111942 W US0111942 W US 0111942W WO 0179221 A3 WO0179221 A3 WO 0179221A3
Authority
WO
WIPO (PCT)
Prior art keywords
il8rb
gene
haplotypes
disclosed
polymorphisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011942
Other languages
French (fr)
Other versions
WO2001079221A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
R Rex Denton
Krishnan Nandabalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001253410A priority Critical patent/AU2001253410A1/en
Publication of WO2001079221A2 publication Critical patent/WO2001079221A2/en
Publication of WO2001079221A3 publication Critical patent/WO2001079221A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Novel single nucleotide polymorphisms in the human interleukin 8 receptor beta (IL8RB) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the IL8RB gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the IL8RB gene in an individual are also disclosed. Polynucleotides containing one or more of the IL8RB polymorphisms disclosed herein are also described.
PCT/US2001/011942 2000-04-12 2001-04-12 Haplotypes of the il8rb gene Ceased WO2001079221A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253410A AU2001253410A1 (en) 2000-04-12 2001-04-12 Haplotypes of the il8rb gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19673400P 2000-04-12 2000-04-12
US60/196,734 2000-04-12

Publications (2)

Publication Number Publication Date
WO2001079221A2 WO2001079221A2 (en) 2001-10-25
WO2001079221A3 true WO2001079221A3 (en) 2002-03-14

Family

ID=22726621

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011942 Ceased WO2001079221A2 (en) 2000-04-12 2001-04-12 Haplotypes of the il8rb gene

Country Status (2)

Country Link
AU (1) AU2001253410A1 (en)
WO (1) WO2001079221A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110036638A (en) 2008-07-25 2011-04-07 리차드 더블유. 와그너 Protein Screening Method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SPRENGER ET AL.: "Structure, genomic organization and expression of the human interleukin-8 receptor B gene", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 15, April 1994 (1994-04-01), pages 11065 - 11072, XP002050852 *
STEPHENS ET AL.: "Haplotype variation and linkage disequilibrium in 313 human genes", SCIENCE, vol. 293, July 2001 (2001-07-01), pages 489 - 493, XP002906129 *
WANG ET AL.: "Large-scale identification, mapping and genotyping of single nucleotide polymorphisms in the human genome", vol. 280, May 1998 (1998-05-01), pages 1077 - 1082, XP002089398 *

Also Published As

Publication number Publication date
AU2001253410A1 (en) 2001-10-30
WO2001079221A2 (en) 2001-10-25

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