IS2339B - Kristallað tíótrópíumbrómíðmónóhýdrat, aðferð viðað framleiða það og notkun þess í framleiðslu á lyfi - Google Patents

Kristallað tíótrópíumbrómíðmónóhýdrat, aðferð viðað framleiða það og notkun þess í framleiðslu á lyfi

Info

Publication number: IS2339B
Authority: IS; Iceland
Prior art keywords: manufacture; medicament; tiotropium bromide; bromide monohydrate; crystalline tiotropium
Prior art date: 2000-10-12

Application number

IS6772A

Other languages

English (en)

Other versions

IS6772A (is

Inventor

Banholzer Rolf

Sieger Peter

Kulinna Christian

Trunk Michael

Ludwig August Graulich Manfred

Specht Peter

Meissner Helmut

Mathes Andreas

Original Assignee

Boehringer Ingelheim Pharma Gmbh & Co. Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2003-04-09

Publication date

2008-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2339(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-04-09 Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg

2003-04-09 Publication of IS6772A publication Critical patent/IS6772A/is

2008-02-15 Publication of IS2339B publication Critical patent/IS2339B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IS6772A 2000-10-12 2003-04-09 Kristallað tíótrópíumbrómíðmónóhýdrat, aðferð viðað framleiða það og notkun þess í framleiðslu á lyfi IS2339B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050621		2000-10-12
PCT/EP2001/011225 WO2002030928A1 (de)	2000-10-12	2001-09-28	Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels

Publications (2)

Publication Number	Publication Date
IS6772A IS6772A (is)	2003-04-09
IS2339B true IS2339B (is)	2008-02-15

Family

ID=7659568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS6772A IS2339B (is)	2000-10-12	2003-04-09	Kristallað tíótrópíumbrómíðmónóhýdrat, aðferð viðað framleiða það og notkun þess í framleiðslu á lyfi

Country Status (46)

Country	Link
EP (2)	EP1326862B1 (is)
JP (1)	JP3764422B2 (is)
KR (1)	KR100823860B1 (is)
CN (2)	CN100519558C (is)
AP (1)	AP1572A (is)
AR (2)	AR034389A1 (is)
AT (1)	ATE276253T1 (is)
AU (2)	AU1499602A (is)
BG (1)	BG66161B1 (is)
BR (1)	BR0114584A (is)
CA (1)	CA2425539C (is)
CR (1)	CR6938A (is)
CZ (1)	CZ301841B6 (is)
DE (1)	DE50103666D1 (is)
DK (1)	DK1326862T3 (is)
DZ (1)	DZ3478A1 (is)
EA (1)	EA004381B1 (is)
EC (1)	ECSP034540A (is)
EE (1)	EE04567B1 (is)
EG (1)	EG24142A (is)
ES (1)	ES2228965T3 (is)
GE (1)	GEP20063905B (is)
HR (1)	HRP20030276B1 (is)
HU (1)	HU226830B1 (is)
IL (2)	IL155335A0 (is)
IS (1)	IS2339B (is)
MA (1)	MA25842A1 (is)
ME (2)	MEP40008A (is)
MX (1)	MXPA03003221A (is)
MY (1)	MY126931A (is)
NO (1)	NO328465B1 (is)
NZ (1)	NZ525733A (is)
OA (1)	OA12403A (is)
PE (1)	PE20020422A1 (is)
PL (1)	PL207870B1 (is)
PT (1)	PT1326862E (is)
RS (1)	RS50218B (is)
SA (1)	SA01220412B1 (is)
SI (1)	SI1326862T1 (is)
SK (1)	SK287009B6 (is)
TR (1)	TR200402579T4 (is)
TW (1)	TW589313B (is)
UA (1)	UA74215C2 (is)
UY (2)	UY26962A1 (is)
WO (1)	WO2002030928A1 (is)
ZA (1)	ZA200302500B (is)

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DE10317461A1 (de)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
JP4553902B2 (ja) *	2003-11-03	2010-09-29	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	抗コリン作用を有する新規結晶性無水物
US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
ATE478071T1 (de) *	2003-11-03	2010-09-15	Boehringer Ingelheim Int	Verfahren zur herstellung neuer tiotropiumsalze
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NZ554930A (en) *	2004-10-21	2010-04-30	Boehringer Ingelheim Int	Blister for inhalers
JP2008532973A (ja) *	2005-03-09	2008-08-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	抗コリン作用薬とｐｄｅ５−阻害剤に基づく新規な医薬組成物
CN101163706A (zh)	2005-04-21	2008-04-16	贝林格尔·英格海姆国际有限公司	用于治疗炎性疾病的二氢噻吩并嘧啶
KR20080007645A (ko)	2005-04-28	2008-01-22	베링거 인겔하임 인터내셔날 게엠베하	염증성 질환 치료용 신규 화합물
RU2007144531A (ru) *	2005-05-02	2009-06-10	БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE)	Новые кристаллические формы тиотропийбромида
SI1881980T1 (sl)	2005-05-02	2012-12-31	Boehringer Ingelheim International Gmbh	Nove kristalinične oblike tiotropijevega bromida
CN101227905A (zh) *	2005-06-15	2008-07-23	贝林格尔·英格海姆国际有限公司	制备噻托铵盐的方法、噻托铵盐及其药物组合物
DE102005030733A1 (de)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
AU2006277968A1 (en) *	2005-08-06	2007-02-15	Boehringer Ingelheim International Gmbh	Use of tiotropium salts in the treatment of severe persistant asthma
BRPI0614410A2 (pt)	2005-08-15	2011-03-29	Boehringer Ingelheim Int	processo para preparação de betamiméticos
TWI396541B (zh)	2005-10-10	2013-05-21	Boehringer Ingelheim Int	用於治療呼吸疾病之新穎藥物組合
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
DE102005059602A1 (de) *	2005-12-14	2007-06-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Mikronisierung
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BRPI0608427A2 (pt)	2005-12-19	2009-12-29	Sicor Inc	novas formas de brometo de tiotrópio e processos para seu preparo
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EP2201934A1 (en)	2008-12-23	2010-06-30	CHIESI FARMACEUTICI S.p.A.	Tiotropium aerosol formulation products with improved chemical stability
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ME01908B (me)	2009-12-17	2014-12-20	Boehringer Ingelheim Int	Novi antagonisti ccr2 receptora i njihova primjena
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US8841313B2 (en)	2010-05-17	2014-09-23	Boehringer Ingelheim International Gmbh	CCR2 antagonists and uses thereof
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EP2576538B1 (en)	2010-06-01	2015-10-28	Boehringer Ingelheim International GmbH	New CCR2 antagonists
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JP5786257B2 (ja)	2011-06-16	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規の選択的ｃｃｒ２拮抗薬
EP2731941B1 (en)	2011-07-15	2019-05-08	Boehringer Ingelheim International GmbH	Novel and selective ccr2 antagonists
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GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
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2001
- 2001-09-28 AP APAP/P/2003/002775A patent/AP1572A/en active
- 2001-09-28 ME MEP-400/08A patent/MEP40008A/xx unknown
- 2001-09-28 PL PL366041A patent/PL207870B1/pl unknown
- 2001-09-28 SI SI200130219T patent/SI1326862T1/xx unknown
- 2001-09-28 CA CA002425539A patent/CA2425539C/en not_active Expired - Lifetime
- 2001-09-28 DZ DZ013478A patent/DZ3478A1/fr active
- 2001-09-28 JP JP2002534314A patent/JP3764422B2/ja not_active Expired - Lifetime
- 2001-09-28 GE GE5214A patent/GEP20063905B/en unknown
- 2001-09-28 PT PT01983510T patent/PT1326862E/pt unknown
- 2001-09-28 IL IL15533501A patent/IL155335A0/xx active IP Right Grant
- 2001-09-28 EA EA200300457A patent/EA004381B1/ru not_active IP Right Cessation
- 2001-09-28 CN CNB2005100977370A patent/CN100519558C/zh not_active Ceased
- 2001-09-28 CN CNB018171435A patent/CN1221549C/zh not_active Ceased
- 2001-09-28 UA UA2003054185A patent/UA74215C2/uk unknown
- 2001-09-28 CZ CZ20031025A patent/CZ301841B6/cs not_active IP Right Cessation
- 2001-09-28 AU AU1499602A patent/AU1499602A/xx active Pending
- 2001-09-28 OA OA1200300107A patent/OA12403A/fr unknown
- 2001-09-28 DE DE50103666T patent/DE50103666D1/de not_active Expired - Lifetime
- 2001-09-28 EE EEP200300171A patent/EE04567B1/xx unknown
- 2001-09-28 DK DK01983510T patent/DK1326862T3/da active
- 2001-09-28 EP EP01983510A patent/EP1326862B1/de not_active Expired - Lifetime
- 2001-09-28 AU AU2002214996A patent/AU2002214996B2/en not_active Expired
- 2001-09-28 TR TR2004/02579T patent/TR200402579T4/xx unknown
- 2001-09-28 WO PCT/EP2001/011225 patent/WO2002030928A1/de not_active Ceased
- 2001-09-28 KR KR1020037005083A patent/KR100823860B1/ko not_active Expired - Lifetime
- 2001-09-28 NZ NZ525733A patent/NZ525733A/en not_active IP Right Cessation
- 2001-09-28 HR HR20030276A patent/HRP20030276B1/xx not_active IP Right Cessation
- 2001-09-28 SK SK436-2003A patent/SK287009B6/sk not_active IP Right Cessation
- 2001-09-28 BR BR0114584-3A patent/BR0114584A/pt not_active Application Discontinuation
- 2001-09-28 ME MEP-2008-400A patent/ME00243B/me unknown
- 2001-09-28 ES ES01983510T patent/ES2228965T3/es not_active Expired - Lifetime
- 2001-09-28 AT AT01983510T patent/ATE276253T1/de active
- 2001-09-28 EP EP04016877A patent/EP1468998A1/de not_active Withdrawn
- 2001-09-28 RS YU27303A patent/RS50218B/sr unknown
- 2001-09-28 HU HU0301022A patent/HU226830B1/hu unknown
- 2001-09-28 MX MXPA03003221A patent/MXPA03003221A/es active IP Right Grant
- 2001-10-02 SA SA01220412A patent/SA01220412B1/ar unknown
- 2001-10-09 EG EG20011058A patent/EG24142A/xx active
- 2001-10-09 TW TW090124963A patent/TW589313B/zh active
- 2001-10-10 PE PE2001001000A patent/PE20020422A1/es active IP Right Grant
- 2001-10-10 MY MYPI20014705A patent/MY126931A/en unknown
- 2001-10-10 UY UY26962A patent/UY26962A1/es not_active Application Discontinuation
- 2001-10-12 AR ARP010104782A patent/AR034389A1/es active IP Right Grant
2003
- 2003-03-26 CR CR6938A patent/CR6938A/es unknown
- 2003-03-28 BG BG107687A patent/BG66161B1/bg unknown
- 2003-03-31 ZA ZA200302500A patent/ZA200302500B/en unknown
- 2003-04-07 EC EC2003004540A patent/ECSP034540A/es unknown
- 2003-04-08 MA MA27102A patent/MA25842A1/fr unknown
- 2003-04-09 IS IS6772A patent/IS2339B/is unknown
- 2003-04-10 IL IL155335A patent/IL155335A/en unknown
- 2003-04-11 NO NO20031694A patent/NO328465B1/no not_active IP Right Cessation
2008
- 2008-09-19 AR ARP080104109A patent/AR068527A2/es unknown
2013
- 2013-07-11 UY UY34901A patent/UY34901A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK1326862T3 (da)	2004-11-22
AU2002214996B2 (en)	2007-03-15
EP1326862B1 (de)	2004-09-15
UY34901A (es)	2015-02-27
AP1572A (en)	2006-02-13
JP3764422B2 (ja)	2006-04-05
WO2002030928A1 (de)	2002-04-18
CN100519558C (zh)	2009-07-29
DE50103666D1 (de)	2004-10-21
YU27303A (sh)	2006-05-25
HK1086557A1 (zh)	2006-09-22
UY26962A1 (es)	2002-06-20
CA2425539A1 (en)	2003-04-11
BG66161B1 (bg)	2011-09-30
CN1733761A (zh)	2006-02-15
CA2425539C (en)	2007-04-03
SA01220412B1 (ar)	2006-11-05
IS6772A (is)	2003-04-09
JP2004526668A (ja)	2004-09-02
EE04567B1 (et)	2005-12-15
TW589313B (en)	2004-06-01
KR20030042008A (ko)	2003-05-27
IL155335A (en)	2009-02-11
ECSP034540A (es)	2003-07-25
SK287009B6 (sk)	2009-09-07
AR068527A2 (es)	2009-11-18
BR0114584A (pt)	2003-08-26
DZ3478A1 (fr)	2002-04-18
EA004381B1 (ru)	2004-04-29
EP1468998A1 (de)	2004-10-20
HUP0301022A2 (hu)	2003-10-28
EA200300457A1 (ru)	2003-10-30
UA74215C2 (uk)	2005-11-15
PT1326862E (pt)	2004-11-30
HK1060567A1 (en)	2004-08-13
EG24142A (en)	2008-08-06
CZ301841B6 (cs)	2010-07-07
MEP40008A (en)	2011-02-10
SK4362003A3 (en)	2003-08-05
MA25842A1 (fr)	2003-07-01
OA12403A (en)	2006-04-18
HUP0301022A3 (en)	2005-12-28
CR6938A (es)	2004-10-28
KR100823860B1 (ko)	2008-04-21
ZA200302500B (en)	2004-04-22
NO328465B1 (no)	2010-02-22
NO20031694L (no)	2003-04-11
SI1326862T1 (sl)	2005-02-28
PE20020422A1 (es)	2002-06-28
AP2003002775A0 (en)	2003-03-31
NZ525733A (en)	2005-01-28
CN1469877A (zh)	2004-01-21
PL366041A1 (en)	2005-01-24
AU1499602A (en)	2002-04-22
RS50218B (sr)	2009-07-15
GEP20063905B (en)	2006-08-25
HRP20030276B1 (en)	2006-02-28
HRP20030276A2 (en)	2005-02-28
AR034389A1 (es)	2004-02-25
MXPA03003221A (es)	2004-12-03
PL207870B1 (pl)	2011-02-28
MY126931A (en)	2006-10-31
ME00243B (me)	2011-05-10
NO20031694D0 (no)	2003-04-11
ES2228965T3 (es)	2005-04-16
BG107687A (bg)	2003-09-30
CN1221549C (zh)	2005-10-05
EE200300171A (et)	2003-06-16
HU226830B1 (en)	2009-11-30
TR200402579T4 (tr)	2004-12-21
IL155335A0 (en)	2003-11-23
EP1326862A1 (de)	2003-07-16
ATE276253T1 (de)	2004-10-15

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