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WO2003091277A3 - Haplotypes of the cetp gene - Google Patents

Haplotypes of the cetp gene Download PDF

Info

Publication number
WO2003091277A3
WO2003091277A3 PCT/US2003/013288 US0313288W WO03091277A3 WO 2003091277 A3 WO2003091277 A3 WO 2003091277A3 US 0313288 W US0313288 W US 0313288W WO 03091277 A3 WO03091277 A3 WO 03091277A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
cetp
gene
disclosed
cetp gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/013288
Other languages
French (fr)
Other versions
WO2003091277A2 (en
Inventor
Alison E Anastasio
Anne Chew
Amir Kazemi
Michael Lachowicz
Helen H Lee
Katie E Parks
Nathan Petersen
Eileen Rounds
Elizabeth Ann Sausker
Charles Tirrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2003239189A priority Critical patent/AU2003239189A1/en
Publication of WO2003091277A2 publication Critical patent/WO2003091277A2/en
Anticipated expiration legal-status Critical
Publication of WO2003091277A3 publication Critical patent/WO2003091277A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Novel genetic variants of the Cholesteryl Ester Transfer Protein (CETP) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the CETP gene. Compositions and methods for haplotyping and/or genotyping the CETP gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2003/013288 2002-04-26 2003-04-28 Haplotypes of the cetp gene Ceased WO2003091277A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003239189A AU2003239189A1 (en) 2002-04-26 2003-04-28 Haplotypes of the cetp gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37579102P 2002-04-26 2002-04-26
US60/375,791 2002-04-26

Publications (2)

Publication Number Publication Date
WO2003091277A2 WO2003091277A2 (en) 2003-11-06
WO2003091277A3 true WO2003091277A3 (en) 2005-04-14

Family

ID=29270700

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2003/013346 Ceased WO2003091698A2 (en) 2002-04-26 2003-04-28 Cetp genetic markers for statin-specific changes in hdl cholesterol
PCT/US2003/013288 Ceased WO2003091277A2 (en) 2002-04-26 2003-04-28 Haplotypes of the cetp gene

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2003/013346 Ceased WO2003091698A2 (en) 2002-04-26 2003-04-28 Cetp genetic markers for statin-specific changes in hdl cholesterol

Country Status (2)

Country Link
AU (2) AU2003239189A1 (en)
WO (2) WO2003091698A2 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE NCBI [online] 29 March 2003 (2003-03-29), DOE JOINT GENOME INSTITUTE: "Direct submission", XP002985097, accession no. STN Database accession no. AC012181 *
DATABASE NCBI [online] September 2000 (2000-09-01), DOE JOINT GENOME INSTITUTE: "Sequencing of human chromosome 16", XP002985096, accession no. STN Database accession no. AC010550 *

Also Published As

Publication number Publication date
AU2003228761A8 (en) 2003-11-10
WO2003091277A2 (en) 2003-11-06
AU2003228761A1 (en) 2003-11-10
WO2003091698A3 (en) 2005-04-21
AU2003239189A1 (en) 2003-11-10
AU2003239189A8 (en) 2003-11-10
WO2003091698A2 (en) 2003-11-06

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