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WO2002026766A3 - Haplotypes of the sstr4 gene - Google Patents

Haplotypes of the sstr4 gene Download PDF

Info

Publication number
WO2002026766A3
WO2002026766A3 PCT/US2001/030410 US0130410W WO0226766A3 WO 2002026766 A3 WO2002026766 A3 WO 2002026766A3 US 0130410 W US0130410 W US 0130410W WO 0226766 A3 WO0226766 A3 WO 0226766A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
sstr4
gene
disclosed
sstr4 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/030410
Other languages
French (fr)
Other versions
WO2002026766A2 (en
Inventor
Karyn M Bieglecki
Julie Y Choi
Stefanie E Kliem
Beena Koshy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001294862A priority Critical patent/AU2001294862A1/en
Publication of WO2002026766A2 publication Critical patent/WO2002026766A2/en
Publication of WO2002026766A3 publication Critical patent/WO2002026766A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel genetic variants of the Somatostatin Receptor 4 (SSTR4) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the SSTR4 gene. Compositions and methods for haplotyping and/or genotyping the SSTR4 gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/030410 2000-09-27 2001-09-27 Haplotypes of the sstr4 gene Ceased WO2002026766A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001294862A AU2001294862A1 (en) 2000-09-27 2001-09-27 Haplotypes of the sstr4 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23582600P 2000-09-27 2000-09-27
US60/235,826 2000-09-27

Publications (2)

Publication Number Publication Date
WO2002026766A2 WO2002026766A2 (en) 2002-04-04
WO2002026766A3 true WO2002026766A3 (en) 2003-01-30

Family

ID=22887064

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/030410 Ceased WO2002026766A2 (en) 2000-09-27 2001-09-27 Haplotypes of the sstr4 gene

Country Status (2)

Country Link
AU (1) AU2001294862A1 (en)
WO (1) WO2002026766A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003057214A1 (en) 2001-12-28 2003-07-17 Somatocor Pharmaceuticals, Inc. Imidazolidin-2,4-dione derivatives as non-peptide somatostatin receptor ligands

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DEMCHYSHYN L.L. ET AL.: "Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20", MOLECULAR PHARMACOLOGY, vol. 43, May 1993 (1993-05-01), pages 894 - 901, XP002952101 *
ROHRER L. ET AL.: "Cloning and characterization of a fourth human somatostatin receptor", PROC. NATL. ACAD. SCI. USA, vol. 90, May 1993 (1993-05-01), pages 4196 - 4200, XP002952102 *
XU Y. ET AL.: "Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 193, no. 2, June 1993 (1993-06-01), pages 648 - 652, XP002952103 *

Also Published As

Publication number Publication date
WO2002026766A2 (en) 2002-04-04
AU2001294862A1 (en) 2002-04-08

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