PL3269366T3 - Kombinacje koniugatu przeciwciało anty-HER2-lek i lapatinibu, i sposoby zastosowania - Google Patents
Kombinacje koniugatu przeciwciało anty-HER2-lek i lapatinibu, i sposoby zastosowaniaInfo
- Publication number
- PL3269366T3 PL3269366T3 PL17167567T PL17167567T PL3269366T3 PL 3269366 T3 PL3269366 T3 PL 3269366T3 PL 17167567 T PL17167567 T PL 17167567T PL 17167567 T PL17167567 T PL 17167567T PL 3269366 T3 PL3269366 T3 PL 3269366T3
- Authority
- PL
- Poland
- Prior art keywords
- lapatinib
- combinations
- methods
- drug conjugate
- her2 antibody
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3741008P | 2008-03-18 | 2008-03-18 | |
| EP13158350.2A EP2644194B1 (en) | 2008-03-18 | 2009-03-10 | Combinations of an anti-HER2 antibody-drug conjugate and docetaxel |
| PCT/US2009/036608 WO2009117277A2 (en) | 2008-03-18 | 2009-03-10 | Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
| EP17167567.1A EP3269366B1 (en) | 2008-03-18 | 2009-03-10 | Combinations of an anti-her2 antibody-drug conjugate and lapatinib, and methods of use |
| EP09721522.2A EP2254571B1 (en) | 2008-03-18 | 2009-03-10 | Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
| EP17150702.3 | 2017-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3269366T3 true PL3269366T3 (pl) | 2020-07-27 |
Family
ID=40858064
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13158391T PL2644204T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i pertuzumabu |
| PL17167567T PL3269366T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciało anty-HER2-lek i lapatinibu, i sposoby zastosowania |
| PL13158350T PL2644194T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i docetakselu |
| PL09721522T PL2254571T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i środki chemioterapeutyczne oraz sposoby zastosowania |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13158391T PL2644204T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i pertuzumabu |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13158350T PL2644194T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i docetakselu |
| PL09721522T PL2254571T3 (pl) | 2008-03-18 | 2009-03-10 | Kombinacje koniugatu przeciwciała anty-HER2-lek i środki chemioterapeutyczne oraz sposoby zastosowania |
Country Status (28)
| Country | Link |
|---|---|
| US (6) | US8663643B2 (pl) |
| EP (6) | EP2644194B1 (pl) |
| JP (5) | JP5656823B2 (pl) |
| KR (9) | KR101751065B1 (pl) |
| CN (5) | CN104888232B (pl) |
| AR (1) | AR070865A1 (pl) |
| AU (1) | AU2009225877B2 (pl) |
| BR (1) | BRPI0906181A2 (pl) |
| CA (3) | CA2716592C (pl) |
| CL (1) | CL2009000559A1 (pl) |
| CR (2) | CR20180483A (pl) |
| DK (3) | DK2644194T3 (pl) |
| ES (4) | ES2629405T3 (pl) |
| HU (3) | HUE025507T2 (pl) |
| IL (8) | IL274393B (pl) |
| MA (1) | MA32223B1 (pl) |
| MX (3) | MX2010010168A (pl) |
| MY (5) | MY201555A (pl) |
| NZ (4) | NZ602675A (pl) |
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