PE20030069A1 - Composicion de liberacion sostenida y proceso para producirla - Google Patents
Composicion de liberacion sostenida y proceso para producirlaInfo
- Publication number
- PE20030069A1 PE20030069A1 PE2002000577A PE2002000577A PE20030069A1 PE 20030069 A1 PE20030069 A1 PE 20030069A1 PE 2002000577 A PE2002000577 A PE 2002000577A PE 2002000577 A PE2002000577 A PE 2002000577A PE 20030069 A1 PE20030069 A1 PE 20030069A1
- Authority
- PE
- Peru
- Prior art keywords
- molecular weight
- produce
- composition
- sustained release
- pro
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XBBVURRQGJPTHH-UHFFFAOYSA-N 2-hydroxyacetic acid;2-hydroxypropanoic acid Chemical compound OCC(O)=O.CC(O)C(O)=O XBBVURRQGJPTHH-UHFFFAOYSA-N 0.000 abstract 1
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 abstract 1
- 108700032845 Ala(2)- enkephalinamide-Met Proteins 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical class C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMPOSICION QUE COMPRENDE: 1)UN POLIMERO DE ACIDO LACTICO-ACIDO GLICOLICO, QUE TIENE UNA RELACION DE PESO MOLECULAR MEDIO, EN PESO A PESO MOLECULAR MEDIO EN NUMERO DE APROXIMADAMENTE 1,90 O MENOS, O UNA SAL DEL MISMO; Y, 2)UNA SUSTANCIA FISIOLOGICAMENTE ACTIVA QUE ES UN PEPTIDO FISIOLOGICAMENTE ACTIVO O UN DERIVADO DE LH-RH QUE ES UN PEPTIDO REPRESENTADO POR LA FORMULA 5-OXO-PRO-HIS-TRP-SER-TYR-Y-LEU-ARG-PRO-Z, SIENDO Y: DLEU, DALA, DTRP, DSER (TBU), D2NAL O DHIS (IMBZL), Y Z SIGNIFICA HH, C2H5 O GLY-NH2, O UNA SAL DEL MISMO. DONDE, EL PESO MOLECULAR DE (1) ES DE 3 000 A 100 000
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001199462 | 2001-06-29 | ||
| JP2001340980 | 2001-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030069A1 true PE20030069A1 (es) | 2003-03-17 |
Family
ID=26617908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002000577A PE20030069A1 (es) | 2001-06-29 | 2002-06-27 | Composicion de liberacion sostenida y proceso para producirla |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US20040241229A1 (es) |
| EP (2) | EP1399133B2 (es) |
| JP (3) | JP5491318B2 (es) |
| KR (3) | KR100988178B1 (es) |
| CN (1) | CN1535141B (es) |
| AR (1) | AR034640A1 (es) |
| AT (1) | ATE429903T1 (es) |
| AU (1) | AU2002311630B2 (es) |
| BR (1) | BR0210572A (es) |
| CA (1) | CA2451718C (es) |
| CO (1) | CO5540368A2 (es) |
| CY (1) | CY1109272T1 (es) |
| CZ (1) | CZ306388B6 (es) |
| DE (1) | DE60232147D1 (es) |
| DK (1) | DK1399133T4 (es) |
| ES (1) | ES2324156T5 (es) |
| HU (1) | HU230152B1 (es) |
| IL (1) | IL159060A0 (es) |
| MX (1) | MXPA03011440A (es) |
| MY (1) | MY139606A (es) |
| NO (1) | NO333531B1 (es) |
| NZ (1) | NZ529968A (es) |
| PE (1) | PE20030069A1 (es) |
| PL (1) | PL212531B1 (es) |
| PT (1) | PT1399133E (es) |
| RU (2) | RU2297240C2 (es) |
| SI (1) | SI1399133T2 (es) |
| SK (1) | SK287568B6 (es) |
| TW (1) | TWI225416B (es) |
| WO (1) | WO2003002091A2 (es) |
| ZA (1) | ZA200309153B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2490351C (en) * | 2002-06-25 | 2011-11-01 | Takeda Pharmaceutical Company Limited | Process for producing sustained-release composition |
| KR100684682B1 (ko) * | 2002-09-24 | 2007-02-22 | 아사히 가세이 케미칼즈 가부시키가이샤 | 글리콜산 공중합체 및 그의 제조 방법 |
| TW200529890A (en) * | 2004-02-10 | 2005-09-16 | Takeda Pharmaceutical | Sustained-release preparations |
| TW200613012A (en) * | 2004-07-02 | 2006-05-01 | Takeda Pharmaceuticals Co | Sustained-release composition, process for producing the same and use of the same |
| DE602006000381T2 (de) * | 2005-04-28 | 2008-12-18 | Nipro Corp., Osaka | Bioabsorbierbare pharmazeutische Zusammensetzung enthaltend einen PLGA-Copolymer |
| MX2008009125A (es) | 2006-01-18 | 2008-10-23 | Qps Llc | Composiciones farmaceuticas con estabilidad mejorada. |
| JP4564098B2 (ja) | 2006-12-18 | 2010-10-20 | 武田薬品工業株式会社 | 徐放性組成物およびその製造法 |
| CA2678350C (en) | 2007-02-15 | 2015-11-17 | Qlt Usa, Inc. | Low-burst poly(lactide-glycolide) |
| KR101008462B1 (ko) * | 2007-07-26 | 2011-01-14 | 조남열 | 치어류 이동용 어도 장치 |
| KR100969641B1 (ko) * | 2007-11-12 | 2010-07-14 | 민선영 | 저수지의 제방용 어도 |
| KR100969642B1 (ko) * | 2007-11-15 | 2010-07-12 | 민선영 | 하천의 보용 어도 |
| US8641900B2 (en) | 2009-11-05 | 2014-02-04 | Taiwan Biotech Co., Ltd | Method and device for continuously preparing microspheres, and collection unit thereof |
| TWI477266B (zh) * | 2009-11-05 | 2015-03-21 | Taiwan Biotech Co Ltd | 連續製備微粒的方法、裝置及其收集單元 |
| EP2697361A1 (en) * | 2011-04-11 | 2014-02-19 | Cellcura Asa | Protein-free culture media products for manufacturing viral-based vaccines |
| US9517210B2 (en) | 2012-07-12 | 2016-12-13 | Takeda Pharmaceutical Company Limited | Method for producing microcapsule powder |
| RU2572992C2 (ru) * | 2012-08-28 | 2016-01-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Курская государственная сельскохозяйственная академия имени И.И. Иванова" | Способ получения микрокапсул водорастворимых препаратов пестицидов |
| EP2985304B1 (en) | 2013-04-11 | 2024-08-14 | Mitsui Chemicals, Inc. | Method for manufacturing lactic acid-glycolic acid copolymer and method for manufacturing salt thereof |
| RU2537248C1 (ru) * | 2013-05-24 | 2014-12-27 | Екатерина Евгеньевна Быковская | Способ получения микрокапсул гетероциклических соединений триазинового ряда |
| RU2537173C1 (ru) * | 2013-05-24 | 2014-12-27 | Александр Александрович Кролевец | Способ получения микрокапсул гетероциклических соединений триазинового ряда |
| JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
| US9956164B2 (en) | 2014-04-16 | 2018-05-01 | Veyx-Pharma Gmbh | Veterinary pharmaceutical composition and use thereof |
| AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
| CN104224731A (zh) * | 2014-09-11 | 2014-12-24 | 北京天晟泰丰医药科技有限公司 | 一种不含致敏性辅料的九肽微球的制备方法 |
| JP5938762B1 (ja) * | 2015-09-01 | 2016-06-22 | 日揮株式会社 | マイクロカプセル製剤及びその製造方法 |
| CN110856690B (zh) * | 2018-08-22 | 2024-07-02 | 深圳善康医药科技股份有限公司 | 一种植入剂包膜及干燥装置 |
| WO2021234731A1 (en) * | 2020-05-18 | 2021-11-25 | Dr Reddy's Institute Of Life Sciences | Sustained release compositions |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| CA1236641A (en) | 1984-07-06 | 1988-05-10 | Motoaki Tanaka | Copolymer of lactic acid and glycolic acid and method for producing same |
| JPH0678425B2 (ja) | 1984-07-06 | 1994-10-05 | 和光純薬工業株式会社 | 重合体の新規製造法 |
| JPH0720859B2 (ja) | 1985-02-07 | 1995-03-08 | 武田薬品工業株式会社 | マイクロカプセルの製造法 |
| DE3678308D1 (de) | 1985-02-07 | 1991-05-02 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
| JP2551756B2 (ja) | 1985-05-07 | 1996-11-06 | 武田薬品工業株式会社 | ポリオキシカルボン酸エステルおよびその製造法 |
| EP0328089A3 (en) | 1988-02-10 | 1990-11-28 | Abbott Laboratories | Reduced size lhrh analogs |
| US5110904A (en) | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
| JP2653255B2 (ja) * | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
| ATE168391T1 (de) † | 1990-04-13 | 1998-08-15 | Takeda Chemical Industries Ltd | Biologisch abbaubare hochmolekulare polymere, ihre herstellung und ihre verwendung |
| JP3200706B2 (ja) | 1990-04-13 | 2001-08-20 | 武田薬品工業株式会社 | 生体内分解型高分子重合物 |
| EP0535937B2 (en) * | 1991-10-01 | 2008-05-21 | Takeda Chemical Industries, Ltd. | Prolonged release microparticle preparation and production of the same |
| JP3277342B2 (ja) | 1992-09-02 | 2002-04-22 | 武田薬品工業株式会社 | 徐放性マイクロカプセルの製造法 |
| TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| JP3761594B2 (ja) * | 1993-07-05 | 2006-03-29 | 武田薬品工業株式会社 | 徐放性製剤の製造法 |
| NZ260909A (en) * | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
| JPH08259460A (ja) | 1995-01-23 | 1996-10-08 | Takeda Chem Ind Ltd | 徐放性製剤の製造法 |
| CA2192782C (en) * | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| JPH11269094A (ja) | 1998-01-16 | 1999-10-05 | Takeda Chem Ind Ltd | 徐放性組成物、その製造法および用途 |
| US6740634B1 (en) * | 1998-01-16 | 2004-05-25 | Takeda Chemical Industries, Ltd. | Sustained release compositions, process for producing the same and utilization thereof |
| WO2000035990A1 (fr) * | 1998-12-15 | 2000-06-22 | Takeda Chemical Industries, Ltd. | Procede de production d'un polymere |
| JP3716146B2 (ja) * | 1998-12-15 | 2005-11-16 | 武田薬品工業株式会社 | ポリマーの製造方法 |
| JP2002114667A (ja) | 2000-10-11 | 2002-04-16 | Ltt Institute Co Ltd | 徐放性製剤用組成物、その製造法および徐放性マイクロカプセル製剤 |
| TW200526267A (en) * | 2001-06-29 | 2005-08-16 | Takeda Chemical Industries Ltd | Controlled release composition and method of producing the same |
| CA2490351C (en) * | 2002-06-25 | 2011-11-01 | Takeda Pharmaceutical Company Limited | Process for producing sustained-release composition |
-
2002
- 2002-06-25 TW TW091113853A patent/TWI225416B/zh not_active IP Right Cessation
- 2002-06-26 AR ARP020102405A patent/AR034640A1/es not_active Application Discontinuation
- 2002-06-27 PE PE2002000577A patent/PE20030069A1/es not_active Application Discontinuation
- 2002-06-27 MY MYPI20022432A patent/MY139606A/en unknown
- 2002-06-28 NZ NZ529968A patent/NZ529968A/en not_active IP Right Cessation
- 2002-06-28 AT AT02738837T patent/ATE429903T1/de active
- 2002-06-28 KR KR1020097017747A patent/KR100988178B1/ko not_active Expired - Lifetime
- 2002-06-28 ES ES02738837T patent/ES2324156T5/es not_active Expired - Lifetime
- 2002-06-28 IL IL15906002A patent/IL159060A0/xx active IP Right Grant
- 2002-06-28 EP EP02738837A patent/EP1399133B2/en not_active Expired - Lifetime
- 2002-06-28 US US10/479,516 patent/US20040241229A1/en not_active Abandoned
- 2002-06-28 CZ CZ2003-3492A patent/CZ306388B6/cs not_active IP Right Cessation
- 2002-06-28 MX MXPA03011440A patent/MXPA03011440A/es active IP Right Grant
- 2002-06-28 SK SK1561-2003A patent/SK287568B6/sk unknown
- 2002-06-28 EP EP09155256A patent/EP2108363A1/en not_active Withdrawn
- 2002-06-28 BR BR0210572-1A patent/BR0210572A/pt not_active Application Discontinuation
- 2002-06-28 WO PCT/JP2002/006526 patent/WO2003002091A2/en not_active Ceased
- 2002-06-28 CN CN028130413A patent/CN1535141B/zh not_active Expired - Lifetime
- 2002-06-28 DE DE60232147T patent/DE60232147D1/de not_active Expired - Lifetime
- 2002-06-28 PL PL367491A patent/PL212531B1/pl not_active IP Right Cessation
- 2002-06-28 RU RU2004102503/15A patent/RU2297240C2/ru active
- 2002-06-28 HU HU0400382A patent/HU230152B1/hu unknown
- 2002-06-28 KR KR10-2003-7017111A patent/KR20040018401A/ko not_active Ceased
- 2002-06-28 PT PT02738837T patent/PT1399133E/pt unknown
- 2002-06-28 SI SI200230837T patent/SI1399133T2/sl unknown
- 2002-06-28 KR KR1020097017748A patent/KR20090096755A/ko not_active Ceased
- 2002-06-28 CA CA2451718A patent/CA2451718C/en not_active Expired - Fee Related
- 2002-06-28 AU AU2002311630A patent/AU2002311630B2/en not_active Expired
- 2002-06-28 DK DK02738837.0T patent/DK1399133T4/da active
-
2003
- 2003-11-25 ZA ZA2003/09153A patent/ZA200309153B/en unknown
- 2003-12-19 NO NO20035737A patent/NO333531B1/no not_active IP Right Cessation
- 2003-12-22 CO CO03111730A patent/CO5540368A2/es not_active Application Discontinuation
-
2006
- 2006-12-05 RU RU2006143104/15A patent/RU2434644C2/ru active
-
2007
- 2007-12-19 US US11/960,114 patent/US8258252B2/en not_active Expired - Fee Related
-
2009
- 2009-07-29 CY CY20091100808T patent/CY1109272T1/el unknown
-
2010
- 2010-08-11 JP JP2010180145A patent/JP5491318B2/ja not_active Expired - Lifetime
-
2012
- 2012-02-15 JP JP2012030788A patent/JP5860300B2/ja not_active Expired - Lifetime
- 2012-08-02 US US13/564,928 patent/US20120295848A1/en not_active Abandoned
-
2014
- 2014-09-10 JP JP2014184482A patent/JP5931147B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20030069A1 (es) | Composicion de liberacion sostenida y proceso para producirla | |
| AR098261A2 (es) | Composición de liberación controlada y método para producirla | |
| CY1107051T1 (el) | Αντι-διηθητικα και αντι-αγγειογενετικα θραυσματα ουροκινασης και η χρηση τους | |
| CY1119723T1 (el) | Φαρμακοτεχνικες μορφες πεπτιδιου περιεχουσες προπυλενογλυκολη οι οποιες ειναι βελτιστες για παραγωγη και για χρηση σε συσκευες ενεσεων | |
| PE20081842A1 (es) | Composicion de liberacion sostenida y metodos para producirlas | |
| JP2003206240A5 (es) | ||
| AR045937A1 (es) | Modulacion de la expresion del factor de iniciacion eucariotico eif4e | |
| BR0208183A (pt) | Peptìdeo modificado por wt1 | |
| NO974270L (no) | Insulinderivater | |
| MX2011011960A (es) | Peptidos penetradores de celulas. | |
| CY1108656T1 (el) | Παραγωγα της πυριμιδινο-2,4-διονης ως ανταγωνιστες των υποδοχεων της εκλυουσας γοναδοτροπινες ορμονης | |
| ATE446758T1 (de) | Verwendung von wachstumshormonsekretagoga zur förderung der beweglichkeit des verdauungstrakts | |
| CY1107668T1 (el) | Χρηση αμινοξικων αντισπασμωδικων για τη θεραπευτικη αγωγη του πονου | |
| BR0313424A (pt) | Forma de dosagem e processo para a preparação de uma forma de dosagem | |
| AR051778A2 (es) | Derivados del acido dimetilaminocrotonico y procesos para supreparacion | |
| PE20020802A1 (es) | COMPUESTO DE LACTAMA COMO INHIBIDOR DE LA LIBERACION DEL PEPTIDO ß-AMILOIDE | |
| JP5982562B2 (ja) | ペプチドの塩酸塩及び他のペプチドとの併用によるその免疫治療用途 | |
| NO20043115L (no) | Substituerte diketopiperaziner som oksytocin antagonister | |
| EP1184035A3 (en) | Use of growth hormone secretagogues for treatment of physical performance decline | |
| CA2471521A1 (en) | Novel microsphere and method for production thereof | |
| ATE205219T1 (de) | Ein verbessertes peptid, immunogene zusammensetzung und impfstoff oder medizinische präparate, eine methode zur immunisierung von tieren gegen das hormon lhrh und analoge des lhrh-tendem-repeat-peptid und deren verwendung als impfstoff | |
| US5491217A (en) | LHRH antagonists having modified aminoacyl residues at positions 5 and 6 | |
| AR015962A1 (es) | LANTIBIoTICO RELACIONADO CON ACTAGARDINA, PROCEDIMIENTO PARA SU PREPARACIoN, MEDICAMENTO, PROCEDIMIENTO PARA LA PREPARACIoN DE UN MEDICAMENTO Y EMPLEO DEL MISMO PARA LA PREPARACIoN DE UN MEDICAMENTO PARA ENFERMEDADES INFECCIOSAS BACTERIANAS. | |
| ECSP099029A (es) | Nuevos análogos del péptido intestinal vasoactivo | |
| AR054340A1 (es) | Composiciones para el tratamiento del cabello |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |