|
EP3153526B1
(en)
|
2008-01-31 |
2020-09-23 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity
|
|
TW202442680A
(zh)
|
2008-12-09 |
2024-11-01 |
美商建南德克公司 |
抗pd-l1抗體及其於增進t細胞功能之用途
|
|
MX343747B
(es)
|
2009-11-24 |
2016-11-22 |
Medimmune Ltd |
Agentes de union diana contra b7-h1.
|
|
CN105218672A
(zh)
|
2009-12-10 |
2016-01-06 |
霍夫曼-拉罗奇有限公司 |
优先结合人csf1r胞外域4的抗体及其用途
|
|
WO2012178137A1
(en)
|
2011-06-24 |
2012-12-27 |
Gillies Stephen D |
Light chain immunoglobulin fusion proteins and methods of use thereof
|
|
PT3409278T
(pt)
|
2011-07-21 |
2020-12-18 |
Sumitomo Dainippon Pharma Oncology Inc |
Inibidores de proteína cinase heterocíclicos
|
|
TWI835048B
(zh)
|
2011-08-01 |
2024-03-11 |
美商建南德克公司 |
利用pd-1軸結合拮抗劑及mek抑制劑治療癌症之方法
|
|
MX349096B
(es)
|
2011-11-28 |
2017-07-11 |
Merck Patent Gmbh |
Anticuerpos anti-pd-l1 y sus usos.
|
|
EA037351B8
(ru)
|
2012-05-15 |
2021-04-29 |
Бристол-Майерс Сквибб Компани |
Способ лечения злокачественных опухолей с использованием комбинации антител против pd-1 и ctla-4
|
|
US9175082B2
(en)
*
|
2012-05-31 |
2015-11-03 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
AU2013285355A1
(en)
|
2012-07-06 |
2015-01-29 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
CN103566377A
(zh)
|
2012-07-18 |
2014-02-12 |
上海博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
EP2904011B1
(en)
|
2012-10-02 |
2017-08-23 |
Bristol-Myers Squibb Company |
Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer
|
|
CN104994873B
(zh)
|
2012-10-04 |
2017-12-22 |
达纳－法伯癌症研究所公司 |
人单克隆抗‑pd‑l1抗体和使用方法
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
US11230589B2
(en)
|
2012-11-05 |
2022-01-25 |
Foundation Medicine, Inc. |
Fusion molecules and uses thereof
|
|
EP2926142B2
(en)
|
2012-11-30 |
2022-07-06 |
F. Hoffmann-La Roche AG |
Identification of patients in need of pd-l1 inhibitor cotherapy
|
|
EP3640375A3
(en)
|
2012-12-11 |
2020-07-29 |
Albert Einstein College of Medicine |
Methods for high throughput receptor/ligand identification
|
|
AR093984A1
(es)
*
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
DK2944323T3
(en)
*
|
2013-01-11 |
2019-04-15 |
Dingfu Biotarget Co Ltd |
Means for the treatment of tumors, their use and their method
|
|
US10980804B2
(en)
|
2013-01-18 |
2021-04-20 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
SG10201710472PA
(en)
|
2013-02-22 |
2018-02-27 |
Curevac Ag |
Combination of vaccination and inhibition of the pd-1 pathway
|
|
BR122021025267B1
(pt)
|
2013-02-22 |
2023-12-05 |
Curevac Ag |
Partes de kit e composição farmacêutica compreendendo um inibidor da via de pd-1
|
|
CA2901269C
(en)
|
2013-03-06 |
2022-01-18 |
Astrazeneca Ab |
Quinazoline inhibitors of activating mutant forms of epidermal growth factor receptor
|
|
WO2014165082A2
(en)
*
|
2013-03-13 |
2014-10-09 |
Medimmune, Llc |
Antibodies and methods of detection
|
|
US9302005B2
(en)
|
2013-03-14 |
2016-04-05 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
US20150071910A1
(en)
*
|
2013-03-15 |
2015-03-12 |
Genentech, Inc. |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
MY176706A
(en)
|
2013-03-15 |
2020-08-19 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
KR20150139955A
(ko)
|
2013-04-09 |
2015-12-14 |
보스톤 바이오메디칼, 인크. |
암 치료에 사용하기 위한 2-아세틸나프토[2,3-b]푸란-4,9-디온
|
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
|
BR112016001420A2
(pt)
|
2013-08-02 |
2018-01-23 |
Aduro Biotech Holdings Europe B V |
combinação de agonistas de cd27 e inibição pontual imune para estimulação imune
|
|
SMT201800421T1
(it)
|
2013-09-06 |
2018-09-13 |
Aurigene Discovery Tech Ltd |
Derivati di 1,3,4-ossadiazolo e 1,3,4-tiadiazolo come immunomodulatori
|
|
HUE048874T2
(hu)
|
2013-09-06 |
2020-08-28 |
Aurigene Discovery Tech Ltd |
1,2,4-oxadiazol-származékok, mint immunmodulátorok
|
|
HUE039012T2
(hu)
|
2013-09-06 |
2018-12-28 |
Aurigene Discovery Tech Ltd |
Gyûrûs peptidomimetikus vegyületek, mint immunomodulátorok
|
|
KR102661249B1
(ko)
*
|
2013-09-11 |
2024-04-25 |
메디뮨 리미티드 |
종양 치료용 항-ｂ7-ｈ1 항체
|
|
AR097584A1
(es)
*
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
|
PL3046584T3
(pl)
|
2013-09-16 |
2017-11-30 |
Astrazeneca Ab |
Terapeutyczne polimeryczne nanocząstki i sposoby ich wytwarzania i stosowania
|
|
US10081681B2
(en)
|
2013-09-20 |
2018-09-25 |
Bristol-Myers Squibb Company |
Combination of anti-LAG-3 antibodies and anti-PD-1 antibodies to treat tumors
|
|
EP3049442A4
(en)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
ES2714708T3
(es)
|
2013-10-01 |
2019-05-29 |
Mayo Found Medical Education & Res |
Procedimientos para el tratamiento de cáncer en pacientes con niveles elevados de Bim
|
|
US10202454B2
(en)
*
|
2013-10-25 |
2019-02-12 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
EP3527587A1
(en)
|
2013-12-17 |
2019-08-21 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-l1 binding antagonists
|
|
AU2014364593A1
(en)
|
2013-12-17 |
2016-07-07 |
Genentech, Inc. |
Methods of treating cancer using PD-1 axis binding antagonists and an anti-CD20 antibody
|
|
SG10201808519VA
(en)
|
2013-12-17 |
2018-10-30 |
Genentech Inc |
Methods of treating her2-positive cancers using pd-1 axis binding antagonists and anti-her2 antibodies
|
|
AU2015203904B2
(en)
*
|
2014-01-06 |
2018-07-19 |
Expression Pathology, Inc. |
SRM assay for PD-L1
|
|
SG11201605296SA
(en)
|
2014-01-10 |
2016-07-28 |
Birdie Biopharmaceuticals Inc |
Compounds and compositions for treating her2 positive tumors
|
|
TWI680138B
(zh)
*
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗ｐｄ-ｌ１之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
DK3105246T3
(da)
|
2014-02-10 |
2021-06-14 |
Merck Patent Gmbh |
Målrettet TGF-beta-inhibering
|
|
CA2942039A1
(en)
|
2014-02-18 |
2015-08-27 |
Health Research, Inc. |
Combination therapy for hepatocellular carcinoma
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
US10307472B2
(en)
|
2014-03-12 |
2019-06-04 |
Curevac Ag |
Combination of vaccination and OX40 agonists
|
|
KR102442436B1
(ko)
|
2014-03-14 |
2022-09-15 |
노파르티스 아게 |
Lag-3에 대한 항체 분자 및 그의 용도
|
|
MX2016012779A
(es)
|
2014-03-31 |
2017-04-27 |
Genentech Inc |
Terapia de combinacion con agentes antiangiogénesis y agonistas de unión a ox40.
|
|
PL3142751T3
(pl)
|
2014-05-13 |
2019-12-31 |
Medimmune Limited |
Przeciwciała anty-b7-h1 i anty-ctla-4 do leczenia niedrobnokomórkowego nowotworu płuca
|
|
CA2949121A1
(en)
|
2014-05-15 |
2015-11-19 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
US10302653B2
(en)
|
2014-05-22 |
2019-05-28 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti B7-H1 antibodies
|
|
SG11201609468WA
(en)
*
|
2014-05-29 |
2016-12-29 |
Medimmune Ltd |
Antagonists of pdl-1 and pd-1 for the treatment of hpv-negative cancers
|
|
ES2753360T3
(es)
|
2014-05-29 |
2020-04-08 |
Spring Bioscience Corp |
Anticuerpos contra PD-L1 y usos de los mismos
|
|
PT3151921T
(pt)
|
2014-06-06 |
2019-11-21 |
Bristol Myers Squibb Co |
Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos
|
|
WO2015195163A1
(en)
*
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
|
KR102130600B1
(ko)
*
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
|
DK3166976T3
(da)
|
2014-07-09 |
2022-04-11 |
Birdie Biopharmaceuticals Inc |
Anti-pd-l1-kombinationer til behandling af tumorer
|
|
ES2916923T3
(es)
|
2014-07-11 |
2022-07-06 |
Ventana Med Syst Inc |
Anticuerpos anti-PD-L1 y usos diagnósticos de los mismos
|
|
WO2016011160A1
(en)
|
2014-07-15 |
2016-01-21 |
Genentech, Inc. |
Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
|
EP3171896A4
(en)
|
2014-07-23 |
2018-03-21 |
Mayo Foundation for Medical Education and Research |
Targeting dna-pkcs and b7-h1 to treat cancer
|
|
HRP20220738T1
(hr)
|
2014-08-11 |
2022-08-19 |
Acerta Pharma B.V. |
Terapijske kombinacije inhibitora btk, inhibitora pd-1 i/ili inhibitora pd-l1
|
|
WO2016030455A1
(en)
|
2014-08-28 |
2016-03-03 |
Medimmune Limited |
Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small lung cancer
|
|
DK3186281T3
(da)
|
2014-08-28 |
2019-06-11 |
Halozyme Inc |
Kombinationsterapi med et hyaluronan-nedbrydende enzym og en immun-checkpoint-inhibitor
|
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
EP3189080A1
(en)
*
|
2014-09-05 |
2017-07-12 |
Medimmune Limited |
Methods for identifying patients responsive to anti-pd-l1 antibody therapy using markers (cxcl9, krt8.trim29, and ifngamma)
|
|
JP6681905B2
(ja)
|
2014-09-13 |
2020-04-15 |
ノバルティス アーゲー |
Ａｌｋ阻害剤の併用療法
|
|
DK3193931T3
(da)
|
2014-09-16 |
2020-10-19 |
Innate Pharma |
Neutralisering af hæmmende veje i lymfocytter
|
|
EP3689910A3
(en)
|
2014-09-23 |
2020-12-02 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
EP3204417B1
(en)
|
2014-10-10 |
2020-07-22 |
Innate Pharma |
Cd73 blockade
|
|
PL3207130T3
(pl)
|
2014-10-14 |
2020-02-28 |
Halozyme, Inc. |
Kompozycje deaminazy adenozyny 2 (ada2), jej warianty i sposoby ich zastosowania
|
|
EA201790834A1
(ru)
|
2014-10-14 |
2018-01-31 |
Новартис Аг |
Молекулы антител к pd-l1 и их применение
|
|
PL3209778T3
(pl)
|
2014-10-24 |
2019-08-30 |
Astrazeneca Ab |
Kombinacja
|
|
JP6755866B2
(ja)
|
2014-11-10 |
2020-09-16 |
メディミューン リミテッド |
Ｃｄ７３特異的結合分子及びその使用
|
|
KR20170096112A
(ko)
|
2014-11-17 |
2017-08-23 |
제넨테크, 인크. |
Ox40 결합 효능제 및 pd-1 축 결합 길항제를 포함하는 조합 요법
|
|
HRP20201928T1
(hr)
|
2014-11-20 |
2021-02-05 |
F. Hoffmann - La Roche Ag |
Kombinirana terapija bispecifičnom antigen vezujućom molekulom koja aktivira t-stanice, za cd3 i folatni receptor 1 (folr1), i antagonistom vezivanja osi pd-1
|
|
WO2016081746A2
(en)
|
2014-11-21 |
2016-05-26 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
ES2807182T3
(es)
|
2014-11-21 |
2021-02-22 |
Bristol Myers Squibb Co |
Anticuerpos frente a CD73 y sus usos
|
|
WO2016090300A1
(en)
|
2014-12-05 |
2016-06-09 |
Genentech, Inc. |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
|
HUE067123T2
(hu)
|
2014-12-09 |
2024-10-28 |
Regeneron Pharma |
Humanizált differenciációs klaszter 274 génnel rendelkezõ nem humán állatok
|
|
JP6180663B2
(ja)
|
2014-12-23 |
2017-08-16 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
Ｔｉｇｉｔに対する抗体
|
|
GB201500319D0
(en)
*
|
2015-01-09 |
2015-02-25 |
Agency Science Tech & Res |
Anti-PD-L1 antibodies
|
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
|
HK1247861A1
(zh)
|
2015-01-30 |
2018-10-05 |
President And Fellows Of Harvard College |
用於癌症治疗的肿瘤周围和肿瘤内部材料
|
|
MA41460A
(fr)
|
2015-02-03 |
2017-12-12 |
Oncomed Pharm Inc |
Agents de liaison à la tnfrsf et leurs utilisations
|
|
EP3254110B1
(en)
|
2015-02-03 |
2020-03-18 |
Ventana Medical Systems, Inc. |
Histochemical assay for evaluating expression of programmed death ligand 1 (pd-l1)
|
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
|
WO2016128912A1
(en)
|
2015-02-12 |
2016-08-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor, and/or a pd-l1 inhibitor
|
|
BR112017018234A2
(pt)
|
2015-02-26 |
2018-04-17 |
Merck Patent Gmbh |
inibidores de pd-1 / pd-l1 para o tratamento de câncer
|
|
JP6769982B2
(ja)
|
2015-03-06 |
2020-10-14 |
ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド |
Ｒａｓ変異と関連するがんの治療方法
|
|
EP3265091A4
(en)
|
2015-03-06 |
2018-08-01 |
Beyondspring Pharmaceuticals Inc. |
Method of treating a brain tumor
|
|
AU2016230793B2
(en)
|
2015-03-10 |
2021-03-25 |
Aurigene Discovery Technologies Limited |
1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
|
|
IL292449B2
(en)
*
|
2015-03-13 |
2024-02-01 |
Cytomx Therapeutics Inc |
Nucleic acids encoding anti-pdl1 antibodie and methods of producing same
|
|
WO2016146143A1
(en)
|
2015-03-16 |
2016-09-22 |
Amal Therapeutics Sa |
Cell penetrating peptides and complexes comprising the same
|
|
JP6815329B2
(ja)
|
2015-03-23 |
2021-01-20 |
バイエル ファーマ アクチエンゲゼルシャフト |
抗ｃｅａｃａｍ６抗体およびその使用
|
|
US11933786B2
(en)
|
2015-03-30 |
2024-03-19 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
US10836827B2
(en)
|
2015-03-30 |
2020-11-17 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
DK3281641T3
(da)
|
2015-04-07 |
2021-01-18 |
Cytlimic Inc |
Adjuvans til cancervacciner
|
|
WO2016166348A1
(en)
*
|
2015-04-17 |
2016-10-20 |
Elsalys Biotech |
Anti-tyro3 antibodies and uses thereof
|
|
CN104830788A
(zh)
*
|
2015-05-05 |
2015-08-12 |
杨光华 |
基于hbv-hcv抗原的dc细胞、靶向性免疫细胞群及其制备方法和用途
|
|
AU2016262074A1
(en)
|
2015-05-12 |
2017-11-09 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
CA2929850A1
(en)
|
2015-05-14 |
2016-11-14 |
Pfizer Inc. |
Combination therapies comprising a pyrrolidine-2,5-dione ido1 inhibitor
|
|
PT3298021T
(pt)
|
2015-05-18 |
2019-08-05 |
Tolero Pharmaceuticals Inc |
Pró-fármacos de alvocidib possuindo biodisponibilidade aumentada
|
|
US20160347848A1
(en)
|
2015-05-28 |
2016-12-01 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
HRP20201031T1
(hr)
|
2015-05-29 |
2020-10-16 |
Agenus Inc. |
Anti-ctla-4 protutijela i postupci njihove upotrebe
|
|
HK1255200A1
(zh)
|
2015-05-29 |
2019-08-09 |
F. Hoffmann-La Roche Ag |
癌症中pd-l1启动子甲基化
|
|
EP3708681A1
(en)
|
2015-05-29 |
2020-09-16 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for cancer
|
|
RS63897B1
(sr)
|
2015-05-29 |
2023-02-28 |
Bristol Myers Squibb Co |
Antitela protiv ox40 i njihova primena
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
CN115554399A
(zh)
|
2015-05-31 |
2023-01-03 |
源生公司 |
用于免疫疗法的组合组合物
|
|
TW201717935A
(zh)
|
2015-06-03 |
2017-06-01 |
波士頓生醫公司 |
用於治療癌症的組成物和方法
|
|
US20170000885A1
(en)
|
2015-06-08 |
2017-01-05 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
|
JP6865177B2
(ja)
|
2015-06-11 |
2021-04-28 |
バイオノミクス リミテッド |
医薬組み合わせおよびその使用
|
|
WO2016197367A1
(en)
|
2015-06-11 |
2016-12-15 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
US20180179282A1
(en)
|
2015-06-12 |
2018-06-28 |
Bristol-Myers Squibb Company |
Treatment of cancer by combined blockade of the pd-1 and cxcr4 signaling pathways
|
|
RU2766890C2
(ru)
|
2015-06-16 |
2022-03-16 |
Мерк Патент Гмбх |
Комбинированные способы лечения антагонистами pd-l1
|
|
EP3310815A1
(en)
|
2015-06-17 |
2018-04-25 |
F. Hoffmann-La Roche AG |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
|
PT3313441T
(pt)
|
2015-06-24 |
2024-05-07 |
Janssen Biotech Inc |
Modulação imunitária e tratamento de tumores sólidos com anticorpos que se ligam especificamente a cd38
|
|
CA2990015A1
(en)
|
2015-06-29 |
2017-01-05 |
The Rockefeller University |
Antibodies to cd40 with enhanced agonist activity
|
|
CN108026075B
(zh)
|
2015-07-13 |
2021-06-29 |
大连万春布林医药有限公司 |
普那布林组合物
|
|
RS61532B1
(sr)
|
2015-07-14 |
2021-04-29 |
Bristol Myers Squibb Co |
Postupak lečenja kancera primenom inhibitora imunološke kontrolne tačke; antitelo koje se vezuje za receptor programirane smrti-1 (pd-1) ili ligand programirane smrti-1 (pd-l1)
|
|
BR112018000917A2
(pt)
|
2015-07-16 |
2018-09-11 |
Bioxcel Therapeutics Inc |
abordagem inovadora para o tratamento de câncer através da imunomodulação
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
CN106397592A
(zh)
*
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
|
WO2017020291A1
(en)
*
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
EP3331919A1
(en)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
|
EA039736B1
(ru)
*
|
2015-09-15 |
2022-03-04 |
Сайтомкс Терапьютикс, Инк. |
Анти-pdl1-антитела, активируемые анти-pdl1-антитела и способы их применения
|
|
EP3356551B1
(en)
|
2015-09-29 |
2020-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining the metabolic status of b-lymphomas
|
|
US20180282415A1
(en)
|
2015-09-30 |
2018-10-04 |
Merck Patent Gmbh |
Combination of a PD-1 Axis Binding Antagonist and an ALK Inhibitor for Treating ALK-Negative Cancer
|
|
CN106565836B
(zh)
*
|
2015-10-10 |
2020-08-18 |
中国科学院广州生物医药与健康研究院 |
高亲和力的可溶性pdl-1分子
|
|
US11130817B2
(en)
|
2015-10-12 |
2021-09-28 |
Innate Pharma |
CD73 blocking agents
|
|
US10875923B2
(en)
|
2015-10-30 |
2020-12-29 |
Mayo Foundation For Medical Education And Research |
Antibodies to B7-H1
|
|
MA43186B1
(fr)
|
2015-11-03 |
2022-03-31 |
Janssen Biotech Inc |
Anticorps se liant spécifiquement à pd-1 et leurs utilisations
|
|
US11702477B2
(en)
|
2015-11-06 |
2023-07-18 |
Orionis Biosciences BV |
Bi-functional chimeric proteins and uses thereof
|
|
WO2017087280A1
(en)
|
2015-11-16 |
2017-05-26 |
Genentech, Inc. |
Methods of treating her2-positive cancer
|
|
CA3004804A1
(en)
|
2015-11-17 |
2017-05-26 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pd-l1 antibody, antigen-binding fragment thereof and medical application thereof
|
|
US11072657B2
(en)
|
2015-11-18 |
2021-07-27 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-PD-1 antibody and an anti-CTLA-4 antibody
|
|
BR112018010172A2
(pt)
|
2015-11-19 |
2018-11-21 |
Bristol Myers Squibb Co |
anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos
|
|
EP3377107B1
(en)
|
2015-11-19 |
2020-08-12 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using b-raf inhibitors and immune checkpoint inhibitors
|
|
RU2018123717A
(ru)
|
2015-12-01 |
2020-01-14 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Комбинированные лечения, их применения и способы
|
|
EP3383412A4
(en)
|
2015-12-02 |
2019-06-05 |
Stcube, Inc. |
SPECIFIC ANTIBODIES TO GLYCOSED PD-1 AND METHOD OF USE THEREOF
|
|
CR20180286A
(es)
|
2015-12-03 |
2018-07-16 |
Glaxosmithkline Ip Dev Ltd |
Dinucleotidos de purina cíclicos como moduladores de sting
|
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
|
ES2901794T3
(es)
|
2015-12-09 |
2022-03-23 |
Hoffmann La Roche |
Anticuerpo anti-CD20 de tipo II para reducir la formación de anticuerpos antifármaco
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
EP3387155A4
(en)
*
|
2015-12-10 |
2019-06-12 |
Definiens AG |
METHOD FOR THE TREATMENT AND SELECTION OF PATIENTS THAT APPLY TO IMMUNE-ACTED CANCER THERAPY
|
|
MA44082A
(fr)
|
2015-12-14 |
2018-10-24 |
Macrogenics Inc |
Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
PT3394103T
(pt)
|
2015-12-22 |
2023-09-04 |
Regeneron Pharma |
Combinação de anticorpos anti-pd-1 e anticorpos biespecíj'icos anti-cd20/anti-cd3 para tratar cancro
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
EP3400443B1
(en)
|
2016-01-04 |
2020-09-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
|
CN106939047B
(zh)
*
|
2016-01-04 |
2021-08-31 |
江苏怀瑜药业有限公司 |
一种pd-l1抗体及其制备方法
|
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技（北京）有限公司 |
用于治疗肿瘤的抗-egfr组合
|
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技（北京）有限公司 |
用于治疗肿瘤的抗-her2组合
|
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技（北京）有限公司 |
用于治疗肿瘤的抗-cd20组合
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
US20190008869A1
(en)
|
2016-01-13 |
2019-01-10 |
Acerta Pharma B.V. |
Therapeutic Combinations of an Antifolate and a BTK Inhibitor
|
|
HUE054356T2
(hu)
|
2016-01-21 |
2021-09-28 |
Innate Pharma |
Gátlási reakcióutak semlegesítése limfocitákban
|
|
CA3013554A1
(en)
|
2016-02-05 |
2017-08-10 |
Orionis Biosciences Nv |
Targeted therapeutic agents and uses thereof
|
|
RU2753543C1
(ru)
|
2016-02-08 |
2021-08-17 |
Бейондспринг Фармасьютикалс, Инк. |
Композиции, содержащие тукаресол или его аналоги
|
|
JP6865762B2
(ja)
|
2016-02-15 |
2021-04-28 |
アストラゼネカ アクチボラグ |
セジラニブの一定間欠投与を含む方法
|
|
EP3420000A1
(en)
*
|
2016-02-25 |
2019-01-02 |
Cell Medica Switzerland AG |
Modified cells for immunotherapy
|
|
JP6821693B2
(ja)
|
2016-02-29 |
2021-01-27 |
ジェネンテック， インコーポレイテッド |
がんのための治療方法及び診断方法
|
|
JP6918816B2
(ja)
|
2016-03-01 |
2021-08-18 |
ノース カロライナ ステート ユニバーシティ |
マイクロニードルパッチ支援送達による強化されたがん免疫療法
|
|
US10465014B2
(en)
*
|
2016-03-04 |
2019-11-05 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
PDL-1 antibody, pharmaceutical composition thereof, and uses thereof
|
|
SG10201913033UA
(en)
|
2016-03-04 |
2020-03-30 |
Bristol Myers Squibb Co |
Combination therapy with anti-cd73 antibodies
|
|
WO2017153433A1
(en)
|
2016-03-08 |
2017-09-14 |
Innate Pharma |
Siglec neutralizing antibodies
|
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
|
WO2017161032A1
(en)
|
2016-03-15 |
2017-09-21 |
North Carolina State University |
Nanoparticles, controlled-release dosage forms, and methods for delivering an immunotherapeutic agent
|
|
CN109153719B
(zh)
|
2016-03-15 |
2022-12-30 |
中外制药株式会社 |
使用pd-1轴结合拮抗剂和抗gpc3抗体治疗癌症的方法
|
|
WO2017161154A2
(en)
|
2016-03-16 |
2017-09-21 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Pd1 and pdl-1 expression during progression from myelodysplastic syndrome to acute myelogenous leukemia
|
|
CA3010779A1
(en)
|
2016-03-16 |
2017-09-21 |
Amal Therapeutics Sa |
Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine
|
|
RU2744959C2
(ru)
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
EP3436475A1
(en)
|
2016-03-29 |
2019-02-06 |
STCube & Co., Inc. |
Methods for selecting antibodies that specifically bind glycosylated immune checkpoint proteins
|
|
WO2017172518A1
(en)
|
2016-03-29 |
2017-10-05 |
Stcube, Inc. |
Dual function antibodies specific to glycosylated pd-l1 and methods of use thereof
|
|
WO2017167921A1
(en)
|
2016-03-30 |
2017-10-05 |
Centre Léon-Bérard |
Lymphocytes expressing cd73 in cancerous patient dictates therapy
|
|
US11209441B2
(en)
|
2016-04-05 |
2021-12-28 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis
|
|
EP3440072B1
(en)
|
2016-04-07 |
2020-01-29 |
GlaxoSmithKline Intellectual Property Development Ltd |
Heterocyclic amides useful as protein modulators
|
|
WO2017176565A1
(en)
|
2016-04-07 |
2017-10-12 |
Eli Lilly And Company |
Combinations of an anti-b7-h1 antibody and a cxcr4 peptide antagonist for treating a solid tumor
|
|
JP6746712B2
(ja)
|
2016-04-07 |
2020-08-26 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
タンパク質調節因子として有用な複素環式アミド
|
|
KR20190003957A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암 모니터링 및 치료 방법
|
|
WO2017181111A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
US10865244B2
(en)
|
2016-04-18 |
2020-12-15 |
Celldex Therapeutics, Inc. |
Nucleic acids encoding agonistic antibodies that bind CD40
|
|
WO2017189433A1
(en)
*
|
2016-04-25 |
2017-11-02 |
Medimmune, Llc |
Compositions comprising coformulation of anti-pd-l1 and anti-ctla-4 antibodies
|
|
MX2018013519A
(es)
|
2016-05-05 |
2019-03-14 |
Glaxosmithkline Ip No 2 Ltd |
Inhibidores del potenciador del homologo zeste 2.
|
|
AR108377A1
(es)
|
2016-05-06 |
2018-08-15 |
Medimmune Llc |
Proteínas de unión biespecíficas y sus usos
|
|
WO2017194782A2
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Therapeutic targeting of non-cellular structures
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
CN109689087B
(zh)
|
2016-05-13 |
2023-04-04 |
奥里尼斯生物科学私人有限公司 |
靶向性突变干扰素-β及其用途
|
|
WO2017201131A1
(en)
|
2016-05-18 |
2017-11-23 |
Albert Einstein College Of Medicine, Inc. |
Variant pd-l1 polypeptides, t-cell modulatory multimeric polypeptides, and methods of use thereof
|
|
BR112018073606A2
(pt)
|
2016-05-18 |
2019-02-26 |
Cue Biopharma, Inc. |
polipeptídeos multiméricos moduladores de células t e métodos de uso dos mesmos
|
|
JP7194022B2
(ja)
|
2016-05-20 |
2022-12-21 |
イーライ リリー アンド カンパニー |
Ｎｏｔｃｈ阻害剤とＰＤ－１またはＰＤ－Ｌ１阻害剤との併用療法
|
|
CA3024508A1
(en)
|
2016-05-27 |
2017-11-30 |
Agenus Inc. |
Anti-tim-3 antibodies and methods of use thereof
|
|
EP3463405A4
(en)
|
2016-05-27 |
2020-02-26 |
DNAtrix, Inc. |
Adenovirus and immunomodulator combination therapy
|
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
|
HRP20230864T1
(hr)
|
2016-06-02 |
2023-11-10 |
Bristol-Myers Squibb Company |
Pd-1 blokada nivolumabom kod refraktornog hodgkinovog limfoma
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
KR20230119265A
(ko)
|
2016-06-02 |
2023-08-16 |
브리스톨-마이어스 스큅 컴퍼니 |
림프종 치료에서의 항-cd30 항체와 조합된 항-pd-1항체의 용도
|
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
|
KR20190015408A
(ko)
|
2016-06-03 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법에 사용하기 위한 항-pd-1 항체
|
|
KR20190015407A
(ko)
|
2016-06-03 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
재발성 소세포 폐암의 치료 방법에 사용하기 위한 항-pd-1 항체
|
|
WO2017210637A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
|
EP3463337A4
(en)
|
2016-06-06 |
2020-02-12 |
Beyondspring Pharmaceuticals, Inc. |
COMPOSITION AND METHOD FOR REDUCING NEUTROPENIA
|
|
MY199278A
(en)
*
|
2016-06-08 |
2023-10-24 |
Abbvie Inc |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
JP2019521109A
(ja)
|
2016-06-08 |
2019-07-25 |
グラクソスミスクライン、インテレクチュアル、プロパテ |
化学化合物
|
|
ES2913929T3
(es)
|
2016-06-08 |
2022-06-06 |
Glaxosmithkline Ip Dev Ltd |
Compuestos químicos como inhibidores de la ruta de ATF4
|
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
RU2018142573A
(ru)
|
2016-06-20 |
2020-07-21 |
Ф-Стар Бета Лимитед |
Партнеры по связыванию lag-3
|
|
CN116903741A
(zh)
|
2016-06-20 |
2023-10-20 |
科马布有限公司 |
特异性结合于pd-l1的抗体或其抗原结合片段及其用途
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
WO2018029474A2
(en)
|
2016-08-09 |
2018-02-15 |
Kymab Limited |
Anti-icos antibodies
|
|
CA3027204A1
(en)
*
|
2016-06-29 |
2018-01-04 |
Checkpoint Therapeutics, Inc. |
Pd-l1-specific antibodies and methods of using the same
|
|
RU2656181C1
(ru)
*
|
2016-07-13 |
2018-05-31 |
Закрытое Акционерное Общество "Биокад" |
Анти-pd-1-антитела, способ их получения и способ применения
|
|
EP4512829A3
(en)
|
2016-07-14 |
2025-06-11 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
AU2017300123A1
(en)
|
2016-07-20 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
Isoquinoline derivatives as PERK inhibitors
|
|
JP2019528251A
(ja)
|
2016-07-20 |
2019-10-10 |
エスティーキューブ，インコーポレイテッド |
グリコシル化ｐｄ−ｌ１に結合する抗体の組合せを使用するがんの処置および治療の方法
|
|
CN106243223B
(zh)
*
|
2016-07-28 |
2019-03-05 |
北京百特美博生物科技有限公司 |
抗人pdl1抗体及其用途
|
|
CN109476748B
(zh)
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
|
CN117736325A
(zh)
|
2016-08-09 |
2024-03-22 |
科马布有限公司 |
分离抗体及其应用
|
|
MX2019001635A
(es)
|
2016-08-12 |
2019-06-10 |
Genentech Inc |
Terapia de combinacion con un inhibidor de mek, un inhibidor del eje de pd-1, y un inhibidor de vegf.
|
|
EP3498838A4
(en)
*
|
2016-08-15 |
2020-01-08 |
National University Corporation Hokkaido University |
ANTI-PD-L1 ANTIBODY
|
|
JP7138094B2
(ja)
|
2016-08-25 |
2022-09-15 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
マクロファージ活性化剤と組み合わせた抗ｃｓｆ－１ｒ抗体の間欠投与
|
|
JP2019526595A
(ja)
|
2016-09-09 |
2019-09-19 |
ティージー セラピューティクス，インコーポレイテッド |
血液癌を治療するための抗ｃｄ２０抗体、ｐｉ３キナーゼ−デルタ阻害剤および抗ｐｄ−１抗体または抗ｐｄ−ｌ１抗体の組み合わせ
|
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
CA3035262A1
(en)
|
2016-09-16 |
2018-03-22 |
Tina Christine Lavranos |
Antibody and checkpoint inhibitor combination therapy
|
|
DK3515476T3
(da)
|
2016-09-21 |
2024-09-02 |
Amal Therapeutics Sa |
Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
|
|
JP7089507B2
(ja)
|
2016-09-26 |
2022-06-22 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｐｄ－１軸阻害剤への応答を予測すること
|
|
EP3519827A1
(en)
|
2016-09-27 |
2019-08-07 |
Oncologie, Inc. |
Methods for treating cancer with bavituximab based on levels of 2-glycoprotein 1, and assays therefor
|
|
CA3038671A1
(en)
|
2016-09-29 |
2018-04-05 |
Genentech, Inc. |
Combination therapy with a mek inhibitor, a pd-1 axis inhibitor, and a taxane
|
|
EP4541423A3
(en)
|
2016-10-06 |
2025-06-25 |
Pfizer Inc. |
Dosing regimen of avelumab for the treatment of cancer
|
|
CN110418851A
(zh)
|
2016-10-06 |
2019-11-05 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
WO2018065625A2
(en)
|
2016-10-07 |
2018-04-12 |
Enterome |
Immunogenic compounds for cancer therapy
|
|
AU2017339577B2
(en)
|
2016-10-07 |
2021-12-02 |
Enterome S.A. |
Immunogenic compounds for cancer therapy
|
|
WO2018065628A2
(en)
|
2016-10-07 |
2018-04-12 |
Enterome |
Microbiota sequence variants of tumor-related antigenic epitopes
|
|
WO2018071500A1
(en)
|
2016-10-11 |
2018-04-19 |
Agenus Inc. |
Anti-lag-3 antibodies and methods of use thereof
|
|
RU2759728C2
(ru)
|
2016-10-11 |
2021-11-17 |
Ситлимик Инк. |
Лекарственное средство
|
|
WO2018077893A1
(en)
|
2016-10-24 |
2018-05-03 |
Orionis Biosciences Nv |
Targeted mutant interferon-gamma and uses thereof
|
|
CN110099925A
(zh)
|
2016-10-28 |
2019-08-06 |
百时美施贵宝公司 |
使用抗pd-1抗体治疗尿道上皮癌的方法
|
|
KR102543323B1
(ko)
|
2016-10-30 |
2023-06-14 |
상하이 헨리우스 바이오테크, 인크. |
항-pd-l1 항체 및 변이체
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
AU2017355446A1
(en)
|
2016-11-03 |
2019-05-02 |
Bristol-Myers Squibb Company |
Activatable anti-CTLA-4 antibodies and uses thereof
|
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
BR112019010878A2
(pt)
|
2016-11-29 |
2019-10-01 |
Lindhofer Horst |
combinação de anticorpos multifuncionais de redirecionamento de células t com moduladores de ponto de verificação imunológico e usos dos mesmos
|
|
US11299469B2
(en)
|
2016-11-29 |
2022-04-12 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Naphthofuran derivatives, preparation, and methods of use thereof
|
|
JP2020500878A
(ja)
|
2016-12-01 |
2020-01-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
併用療法
|
|
CN110234342A
(zh)
|
2016-12-01 |
2019-09-13 |
葛兰素史密斯克莱知识产权发展有限公司 |
组合疗法
|
|
KR20190104529A
(ko)
|
2016-12-03 |
2019-09-10 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Car-t 세포의 조절 방법
|
|
AU2017373945B2
(en)
|
2016-12-07 |
2025-01-23 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
US11013802B2
(en)
|
2016-12-07 |
2021-05-25 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
EP3552626A4
(en)
|
2016-12-12 |
2020-06-10 |
Daiichi Sankyo Company, Limited |
ASSOCIATION OF AN ANTIBODY DRUG CONJUGATE AND AN IMMUNE CONTROL POINT INHIBITOR
|
|
KR20190095921A
(ko)
|
2016-12-12 |
2019-08-16 |
제넨테크, 인크. |
항-pd-l1 항체 및 안티안드로겐을 사용하여 암을 치료하는 방법
|
|
WO2018111976A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Pd-l1 binding fibronectin type iii domains
|
|
US10611823B2
(en)
|
2016-12-14 |
2020-04-07 |
Hanssen Biotech, Inc |
CD137 binding fibronectin type III domains
|
|
BR112019012154A2
(pt)
|
2016-12-14 |
2019-11-12 |
Janssen Biotech Inc |
domínios do tipo iii da fibronectina de ligação a cd8a
|
|
WO2018112364A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating melanoma
|
|
WO2018112360A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating cancer
|
|
WO2018119114A1
(en)
|
2016-12-22 |
2018-06-28 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
CN110072553B
(zh)
|
2016-12-22 |
2023-09-15 |
豪夫迈·罗氏有限公司 |
在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗
|
|
KR102679324B1
(ko)
|
2017-01-05 |
2024-06-28 |
네트리 파르마 |
네트린-1 간섭 약물과 면역 관문 억제제 약물의 조합 치료
|
|
WO2018129381A1
(en)
|
2017-01-06 |
2018-07-12 |
Beyondspring Pharmaceuticals, Inc. |
Tubulin binding compounds and therapeutic use thereof
|
|
WO2018129497A1
(en)
|
2017-01-09 |
2018-07-12 |
Bioxcel Therapeutics, Inc. |
Predictive and diagnostic methods for prostate cancer
|
|
EP3565549B1
(en)
|
2017-01-09 |
2022-03-09 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
US11851471B2
(en)
|
2017-01-09 |
2023-12-26 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
KR20190103226A
(ko)
|
2017-01-13 |
2019-09-04 |
아게누스 인코포레이티드 |
Ny-eso-1에 결합하는 t 세포 수용체 및 이의 사용 방법
|
|
BR112019015069A2
(pt)
|
2017-01-24 |
2020-03-03 |
Pfizer Inc. |
Derivados de caliqueamicina e conjugados de anticorpo-fármaco dos mesmos
|
|
SG11201907023UA
(en)
|
2017-02-01 |
2019-08-27 |
Beyondspring Pharmaceuticals Inc |
Method of reducing neutropenia
|
|
US11384154B2
(en)
|
2017-02-06 |
2022-07-12 |
Orionis Biosciences BV |
Targeted chimeric proteins and uses thereof
|
|
EP3577138A1
(en)
|
2017-02-06 |
2019-12-11 |
Innate Pharma |
Immunomodulatory antibody drug conjugates binding to a human mica polypeptide
|
|
US10906985B2
(en)
|
2017-02-06 |
2021-02-02 |
Orionis Biosciences, Inc. |
Targeted engineered interferon and uses thereof
|
|
EP3583127B1
(en)
|
2017-02-16 |
2024-11-20 |
Ying Zhang |
Anti-programmed death-ligand 1 (pd-l1) antibodies and therapeutic uses thereof
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
IL268479B2
(en)
|
2017-02-21 |
2024-06-01 |
Regeneron Pharma |
Anti-PD-1 antibodies for the treatment of lung cancer
|
|
CN108456251A
(zh)
|
2017-02-21 |
2018-08-28 |
上海君实生物医药科技股份有限公司 |
抗pd-l1抗体及其应用
|
|
CA3053803A1
(en)
|
2017-02-24 |
2018-08-30 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
|
CA3052767A1
(en)
|
2017-02-27 |
2018-08-30 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors
|
|
AU2018228873A1
(en)
|
2017-03-01 |
2019-08-29 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
CN109843927B
(zh)
*
|
2017-03-06 |
2022-06-21 |
江苏恒瑞医药股份有限公司 |
抗b7-h3抗体、其抗原结合片段及其医药用途
|
|
LT3592769T
(lt)
*
|
2017-03-09 |
2024-08-26 |
Genmab A/S |
Antikūnai, atpažįstantys pd-l1
|
|
EP3596118B1
(en)
|
2017-03-15 |
2024-08-21 |
Cue Biopharma, Inc. |
Combination of multimeric fusion polypeptides and immune checkpoint inhibitor for treating hpv-associated cancer
|
|
EP3596075B1
(en)
|
2017-03-15 |
2023-10-11 |
F. Hoffmann-La Roche AG |
Azaindoles as inhibitors of hpk1
|
|
WO2018167267A1
(en)
|
2017-03-16 |
2018-09-20 |
Innate Pharma |
Compositions and methods for treating cancer
|
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
|
KR102644408B1
(ko)
|
2017-03-30 |
2024-03-07 |
메르크 파텐트 게엠베하 |
암의 치료를 위한 항-pd-l1 항체 및 dna-pk 억제제의 병용
|
|
AU2018244935A1
(en)
|
2017-03-30 |
2019-08-15 |
F. Hoffmann-La Roche Ag |
Naphthyridines as inhibitors of HPK1
|
|
CN110709392B
(zh)
|
2017-03-30 |
2023-09-29 |
豪夫迈·罗氏有限公司 |
作为hpk1抑制剂的异喹啉
|
|
WO2018183928A1
(en)
|
2017-03-31 |
2018-10-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3606960A1
(en)
|
2017-04-03 |
2020-02-12 |
Oncologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
JP7297672B2
(ja)
|
2017-04-13 |
2023-06-26 |
アジェナス インコーポレイテッド |
抗ｃｄ１３７抗体およびその使用方法
|
|
BR112019021411A2
(pt)
|
2017-04-13 |
2020-05-05 |
Hoffmann La Roche |
métodos para tratar ou retardar a progressão do câncer e para melhorar a função, usos de um imunoconjugado, de um agonista, de um antagonista, composições, kit e invenção
|
|
TW201839400A
(zh)
|
2017-04-14 |
2018-11-01 |
美商建南德克公司 |
用於癌症之診斷及治療方法
|
|
RU2665790C1
(ru)
*
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
|
US12460208B2
(en)
|
2017-04-18 |
2025-11-04 |
Parr Biotechnology Co., Ltd. |
Immunomodulatory polynucleotides and uses thereof
|
|
US20200085891A1
(en)
|
2017-04-21 |
2020-03-19 |
Sillajen, Inc |
Oncolytic vaccinia virus and checkpoint inhibitor combination therapy
|
|
JP2020517699A
(ja)
|
2017-04-26 |
2020-06-18 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
ジスルフィド結合の還元を最小限にする抗体製造法
|
|
CN118515666A
(zh)
|
2017-04-27 |
2024-08-20 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
US11021537B2
(en)
|
2017-05-01 |
2021-06-01 |
Agenus Inc. |
Anti-TIGIT antibodies and methods of use thereof
|
|
KR20200018436A
(ko)
|
2017-05-09 |
2020-02-19 |
테사로, 인코포레이티드 |
암 치료를 위한 조합 요법
|
|
MX2019013023A
(es)
|
2017-05-12 |
2019-12-18 |
Jiangsu Hengrui Medicine Co |
Proteina de fusion con receptor tgf-?, y uso farmaceutico de la misma.
|
|
JP7263256B6
(ja)
*
|
2017-05-16 |
2023-07-24 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
Ｐｄ－ｌ１抗体医薬組成物およびその使用
|
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
|
CA3062656A1
(en)
|
2017-05-17 |
2018-11-22 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
CA3063715A1
(en)
|
2017-05-18 |
2018-11-22 |
Tesaro, Inc. |
Combination therapies for treating cancer
|
|
EP3630833A1
(en)
|
2017-05-25 |
2020-04-08 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
WO2018219956A1
(en)
|
2017-05-29 |
2018-12-06 |
Gamamabs Pharma |
Cancer-associated immunosuppression inhibitor
|
|
WO2018222722A2
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising an anti-lag-3 antibody or an anti-lag-3 antibody and an anti-pd-1 or anti-pd-l1 antibody
|
|
IL322104A
(en)
|
2017-05-30 |
2025-09-01 |
Bristol Myers Squibb Co |
Treatment of lag-3 positive tumors
|
|
CN110691795A
(zh)
|
2017-05-30 |
2020-01-14 |
百时美施贵宝公司 |
包含抗-lag3抗体、pd-1途径抑制剂和免疫治疗剂组合的组合物
|
|
JP2020522486A
(ja)
|
2017-06-01 |
2020-07-30 |
サイトメックス セラピューティクス インコーポレイテッド |
活性化可能抗ｐｄｌ１抗体、およびその使用方法
|
|
CN110678483B
(zh)
|
2017-06-01 |
2023-09-22 |
百时美施贵宝公司 |
用抗pd-1抗体治疗肿瘤的方法
|
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
|
EP3634483A1
(en)
|
2017-06-09 |
2020-04-15 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CN110785187B
(zh)
|
2017-06-22 |
2024-04-05 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
TW201904993A
(zh)
|
2017-06-22 |
2019-02-01 |
瑞士商諾華公司 |
IL-1β 結合抗體之用途
|
|
US11517567B2
(en)
|
2017-06-23 |
2022-12-06 |
Birdie Biopharmaceuticals, Inc. |
Pharmaceutical compositions
|
|
AU2018291081B2
(en)
|
2017-06-27 |
2025-02-20 |
Neuracle Science Co., Ltd. |
Use of anti-FAM19A5 antibodies for treating cancers
|
|
US20200223924A1
(en)
|
2017-06-27 |
2020-07-16 |
Novartis Ag |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
JP2020525513A
(ja)
|
2017-07-03 |
2020-08-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
癌および他の疾患を治療するためのａｔｆ４阻害剤としてのｎ−（３−（２−（４−クロロフェノキシ）アセトアミドビシクロ［１．１．１］ペンタン−１−イル）−２−シクロブタン−１−カルボキサミド誘導体および関連化合物
|
|
CA3068395A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
2-(4-chlorophenoxy)-n-((1-(2-(4-chlorophenoxy)ethynazetidin-3-yl)methyl)acetamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
|
CN111263769B
(zh)
|
2017-07-10 |
2024-01-02 |
先天制药公司 |
Siglec-9中和性抗体
|
|
NZ761519A
(en)
|
2017-07-14 |
2023-07-28 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
MX2020000604A
(es)
|
2017-07-21 |
2020-09-10 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
|
CN111148996A
(zh)
|
2017-07-28 |
2020-05-12 |
百时美施贵宝公司 |
用于检查点抑制剂的预测性外周血生物标志物
|
|
CN111406067B
(zh)
|
2017-08-04 |
2022-11-08 |
健玛保 |
与pd-l1和cd137结合的结合剂及其用途
|
|
JP2020530003A
(ja)
|
2017-08-07 |
2020-10-15 |
アムジェン インコーポレイテッド |
抗ｐｄ−ｌ１抗体及び腫瘍溶解性ウイルスでの、肝転移を伴う三種陰性乳がん又は結腸直腸がんの処置
|
|
KR20200044899A
(ko)
|
2017-08-28 |
2020-04-29 |
브리스톨-마이어스 스큅 컴퍼니 |
암의 치료 및 진단을 위한 tim-3 길항제
|
|
MA50084A
(fr)
|
2017-09-04 |
2020-07-15 |
Agenus Inc |
Récepteurs de lymphocytes t qui se lient à des phosphopeptides spécifiques de la leucémie de lignée mixte (mll) et méthodes d'utilisation de ces derniers
|
|
TW201922721A
(zh)
|
2017-09-07 |
2019-06-16 |
英商葛蘭素史克智慧財產發展有限公司 |
化學化合物
|
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
|
WO2019061324A1
(en)
|
2017-09-29 |
2019-04-04 |
Curis Inc. |
CRYSTALLINE FORMS OF IMMUNOMODULATORS
|
|
JP2020536066A
(ja)
|
2017-09-30 |
2020-12-10 |
テサロ， インコーポレイテッド |
癌を治療するための併用療法
|
|
EA039662B1
(ru)
|
2017-10-03 |
2022-02-24 |
Закрытое Акционерное Общество "Биокад" |
Антитела, специфичные к cd47 и pd-l1
|
|
US11377440B2
(en)
|
2017-10-05 |
2022-07-05 |
Glaxosmithkline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (STING)
|
|
EP3692033A1
(en)
|
2017-10-05 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (sting) useful in treating hiv
|
|
CN111182923A
(zh)
|
2017-10-06 |
2020-05-19 |
特沙诺有限公司 |
组合疗法及其用途
|
|
AU2018346447B2
(en)
|
2017-10-06 |
2025-06-19 |
Innate Pharma |
Restoration of T cell activity via the CD39/CD73 axis
|
|
US20200256877A1
(en)
|
2017-10-09 |
2020-08-13 |
Enterome S.A. |
Microbiota Sequence Variants Of Tumor-Related Antigenic Epitopes
|
|
CA3075337A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
|
CN120248120A
(zh)
*
|
2017-10-10 |
2025-07-04 |
努玛治疗有限公司 |
靶向pdl1的抗体及其使用方法
|
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
WO2019072868A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
MULTISPECIFIC ANTIBODIES
|
|
EP3694841A1
(en)
|
2017-10-11 |
2020-08-19 |
Aurigene Discovery Technologies Limited |
Crystalline forms of 3-substituted 1,2,4-oxadiazole
|
|
EP4116327A1
(en)
|
2017-10-11 |
2023-01-11 |
Board Of Regents, The University Of Texas System |
Human pd-l1 antibodies and methods of use therefor
|
|
KR20200064132A
(ko)
|
2017-10-15 |
2020-06-05 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
SG11202003078VA
(en)
|
2017-10-18 |
2020-05-28 |
Alpine Immune Sciences Inc |
Variant icos ligand immunomodulatory proteins and related compositions and methods
|
|
CN111655725A
(zh)
|
2017-10-19 |
2020-09-11 |
德比奥药物国际股份有限公司 |
用于治疗癌症的组合产品
|
|
US20210040205A1
(en)
|
2017-10-25 |
2021-02-11 |
Novartis Ag |
Antibodies targeting cd32b and methods of use thereof
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
MX2020004531A
(es)
|
2017-11-03 |
2020-08-03 |
Aurigene Discovery Tech Ltd |
Inhibidores dobles de tim-3 y las vias de pd-1.
|
|
EP3706798A1
(en)
|
2017-11-06 |
2020-09-16 |
Aurigene Discovery Technologies Limited |
Conjoint therapies for immunomodulation
|
|
KR20200084880A
(ko)
|
2017-11-06 |
2020-07-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
TW201923089A
(zh)
|
2017-11-06 |
2019-06-16 |
美商建南德克公司 |
癌症之診斷及治療方法
|
|
WO2019094265A1
(en)
*
|
2017-11-10 |
2019-05-16 |
Armo Biosciences, Inc. |
Pd1 polypeptide binding molecules
|
|
SG11202003477QA
(en)
|
2017-11-14 |
2020-05-28 |
Pfizer |
Ezh2 inhibitor combination therapies
|
|
AU2018375738A1
(en)
|
2017-11-30 |
2020-06-11 |
Novartis Ag |
BCMA-targeting chimeric antigen receptor, and uses thereof
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
WO2019122882A1
(en)
|
2017-12-19 |
2019-06-27 |
Kymab Limited |
Bispecific antibody for icos and pd-l1
|
|
CN108144745B
(zh)
*
|
2017-12-20 |
2020-06-16 |
天康生物股份有限公司 |
一种分离装置以及减少布氏菌病活疫苗的内毒素含量的方法
|
|
KR102813744B1
(ko)
|
2017-12-27 |
2025-05-28 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd40 항체 및 그의 용도
|
|
CN109970856B
(zh)
|
2017-12-27 |
2022-08-23 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
|
US11407723B2
(en)
|
2018-01-09 |
2022-08-09 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
EP3737689A4
(en)
|
2018-01-09 |
2021-12-01 |
Cue Biopharma, Inc. |
MULTIMERIC T CELL-MODULATING POLYPEPTIDES AND METHOD OF USING THEREOF
|
|
CA3087105A1
(en)
*
|
2018-01-10 |
2019-07-18 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pd-l1 antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
|
|
EP3737696A1
(en)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2019140229A1
(en)
|
2018-01-12 |
2019-07-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
WO2019143607A1
(en)
|
2018-01-16 |
2019-07-25 |
Bristol-Myers Squibb Company |
Methods of treating cancer with antibodies against tim3
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
AU2019210332A1
(en)
|
2018-01-22 |
2020-09-10 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
EP3743076A1
(en)
|
2018-01-22 |
2020-12-02 |
Bristol-Myers Squibb Company |
Compositions and methods of treating cancer
|
|
BR112020014960A2
(pt)
|
2018-01-24 |
2020-12-22 |
Beyondspring Pharmaceuticals, Inc. |
Composição e método para redução de trombocitopenia
|
|
WO2019148089A1
(en)
|
2018-01-26 |
2019-08-01 |
Orionis Biosciences Inc. |
Xcr1 binding agents and uses thereof
|
|
KR20200128014A
(ko)
|
2018-01-31 |
2020-11-11 |
셀진 코포레이션 |
입양 세포 요법 및 체크포인트 억제제를 이용한 병용 요법
|
|
AU2019215031B2
(en)
|
2018-01-31 |
2025-10-09 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
CA3090406A1
(en)
|
2018-02-05 |
2019-08-08 |
Orionis Biosciences, Inc. |
Fibroblast binding agents and use thereof
|
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
EP3756012A1
(en)
|
2018-02-21 |
2020-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
|
WO2019165195A1
(en)
|
2018-02-22 |
2019-08-29 |
Srivastava Satish |
Combination therapy for the treatment of cancer
|
|
WO2019165434A1
(en)
|
2018-02-26 |
2019-08-29 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
RU2020133451A
(ru)
|
2018-03-12 |
2022-04-12 |
Инститьют Насьонал Де Ла Санте Et De La Решерш Медикаль (Инсерм) |
Применение терапевтически эффективной комбинации химиотерапиии и ингибитора контрольной точки иммунного ответа с миметиком ограничения калорийности для лечения рака
|
|
EP3765019A1
(en)
|
2018-03-14 |
2021-01-20 |
Merck Patent GmbH |
Compounds and uses thereof to treat tumors in a subject
|
|
KR102874694B1
(ko)
|
2018-03-21 |
2025-10-23 |
파이브 프라임 테라퓨틱스, 인크. |
산성 pH에서 VISTA에 결합하는 항체
|
|
EP4501355A3
(en)
|
2018-03-23 |
2025-04-30 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
|
|
TW202003565A
(zh)
|
2018-03-23 |
2020-01-16 |
美商必治妥美雅史谷比公司 |
抗mica及/或micb抗體及其用途
|
|
CN117586412A
(zh)
|
2018-03-23 |
2024-02-23 |
得克萨斯州大学系统董事会 |
针对人pd-l1和pd-l2的双重特异性抗体及其使用方法
|
|
CN119101158A
(zh)
|
2018-03-23 |
2024-12-10 |
得克萨斯州大学系统董事会 |
人pd-l2抗体及其使用方法
|
|
TW202003569A
(zh)
|
2018-03-30 |
2020-01-16 |
荷蘭商美勒斯公司 |
多價抗體
|
|
US20210032344A1
(en)
|
2018-03-30 |
2021-02-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3774903A1
(en)
|
2018-04-04 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-cd27 antibodies and uses thereof
|
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
|
KR20200142542A
(ko)
|
2018-04-12 |
2020-12-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73 길항제 항체 및 pd-1/pd-l1 축 길항제 항체에 의한 항암 조합 요법
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
KR20210011919A
(ko)
|
2018-04-17 |
2021-02-02 |
셀덱스 쎄라퓨틱스, 인크. |
항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물
|
|
KR20210010862A
(ko)
|
2018-04-18 |
2021-01-28 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 PD-1 항원 결합 도메인을 함유하는 PD-1 표적화 이종이량체 융합 단백질 및 이의 용도
|
|
MA52289A
(fr)
|
2018-04-18 |
2021-02-24 |
Xencor Inc |
Protéines de fusion fc hétérodimères il-15/il-15ra et leurs utilisations
|
|
EA202092508A1
(ru)
*
|
2018-04-25 |
2021-03-16 |
Медиммун Лимитед |
Составы на основе антител к pd-l1 человека
|
|
US20230182041A1
(en)
*
|
2018-04-25 |
2023-06-15 |
Medimmune, Llc |
Purification of antibodies
|
|
AU2019261582A1
(en)
|
2018-04-25 |
2020-11-12 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
CA3096909A1
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
WO2019211492A1
(en)
|
2018-05-04 |
2019-11-07 |
Tollys |
Tlr3 ligands that activate both epithelial and myeloid cells
|
|
US20210246208A1
(en)
|
2018-05-04 |
2021-08-12 |
Merck Patent Gmbh |
Combined inhibition of pd-1/pd-l1, tgfb and dna-pk for the treatment of cancer
|
|
US12209126B2
(en)
|
2018-05-15 |
2025-01-28 |
Medimmune Limited |
Treatment of cancer
|
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
US11932681B2
(en)
|
2018-05-31 |
2024-03-19 |
Novartis Ag |
Hepatitis B antibodies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
BR112020024351A2
(pt)
|
2018-06-01 |
2021-02-23 |
Novartis Ag |
moléculas de ligação contra bcma e usos das mesmas
|
|
JP2021528393A
(ja)
|
2018-06-15 |
2021-10-21 |
フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド |
後細胞シグナル伝達因子の調節による免疫活性の上昇
|
|
US11377503B2
(en)
|
2018-06-18 |
2022-07-05 |
Innate Pharma |
Antibodies that bind human CD39 and inhibit ATPase activity of a soluble extracellular domain human CD39 polypeptide
|
|
CN112585166A
(zh)
|
2018-06-23 |
2021-03-30 |
豪夫迈·罗氏有限公司 |
用pd-1轴结合拮抗剂、铂剂和拓扑异构酶ii抑制剂治疗肺癌的方法
|
|
EP3820904A2
(en)
|
2018-07-09 |
2021-05-19 |
Five Prime Therapeutics, Inc. |
Antibodies binding to ilt4
|
|
CA3105942A1
(en)
|
2018-07-09 |
2020-01-16 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
BR112020026947B1
(pt)
|
2018-07-10 |
2022-11-22 |
Novartis Ag |
Derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6-diona, e composição farmacêutica
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
JP7340591B2
(ja)
|
2018-07-11 |
2023-09-07 |
アクティム・セラピューティクス・インコーポレイテッド |
遺伝子操作された免疫刺激性細菌菌株およびその使用
|
|
CN121203021A
(zh)
|
2018-07-11 |
2025-12-26 |
戊瑞治疗有限公司 |
在酸性pH下结合至VISTA的抗体
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
US12344672B2
(en)
|
2018-07-12 |
2025-07-01 |
Invox Pharma Limited |
Antibody molecules that bind PD-L1 and CD137
|
|
MX2021000399A
(es)
|
2018-07-12 |
2021-05-27 |
F Star Therapeutics Ltd |
Moleculas de anticuerpo que se unen a cd137 y ox40.
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
|
TWI822815B
(zh)
*
|
2018-07-14 |
2023-11-21 |
財團法人生物技術開發中心 |
抗-人類ｐｄ-ｌ１之抗體及其用途
|
|
US20200171146A1
(en)
|
2018-07-18 |
2020-06-04 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗ｃｄ１１２ｒ組成物及び方法
|
|
EP3826721B1
(en)
|
2018-07-24 |
2023-10-11 |
F. Hoffmann-La Roche AG |
Naphthyridine compounds and uses thereof
|
|
TW202019905A
(zh)
|
2018-07-24 |
2020-06-01 |
瑞士商赫孚孟拉羅股份公司 |
異喹啉化合物及其用途
|
|
JP2021532143A
(ja)
|
2018-07-26 |
2021-11-25 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌の処置のためのｌａｇ−３併用療法
|
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
EP3837015B1
(en)
|
2018-08-16 |
2024-02-14 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
CA3109778A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Substitued 4-amino-1h-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
|
|
EP3837014B1
(en)
|
2018-08-16 |
2022-10-19 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
JP7488534B2
(ja)
*
|
2018-08-20 |
2024-05-22 |
１グローブ バイオメディカル カンパニー， リミテッド |
新規ながん免疫療法抗体組成物
|
|
CN112955221A
(zh)
|
2018-08-27 |
2021-06-11 |
皮里斯制药有限公司 |
包含cd137/her2双特异性试剂和pd-1轴抑制剂的组合疗法及其用途
|
|
WO2020044206A1
(en)
|
2018-08-29 |
2020-03-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors for use in the treatment cancer
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗ｐｄ－１抗體難治療性之非小細胞肺癌（ｎｓｃｌｃ）病患的治療
|
|
CN112805267B
(zh)
|
2018-09-03 |
2024-03-08 |
豪夫迈·罗氏有限公司 |
用作tead调节剂的甲酰胺和磺酰胺衍生物
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
|
US11992520B2
(en)
|
2018-09-18 |
2024-05-28 |
Vanderbilt University |
Human monoclonal antibodies to Staphylococcal aureus Isd proteins and uses thereof
|
|
JP2022501332A
(ja)
|
2018-09-19 |
2022-01-06 |
ジェネンテック， インコーポレイテッド |
膀胱がんの治療方法および診断方法
|
|
US20220073638A1
(en)
|
2018-09-19 |
2022-03-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
CN113015526A
(zh)
|
2018-09-19 |
2021-06-22 |
豪夫迈·罗氏有限公司 |
螺环2,3-二氢-7-氮杂吲哚化合物及其用途
|
|
SG11202101787XA
(en)
|
2018-09-20 |
2021-04-29 |
Iovance Biotherapeutics Inc |
Expansion of tils from cryopreserved tumor samples
|
|
AU2019342133B8
(en)
|
2018-09-21 |
2025-08-07 |
Genentech, Inc. |
Diagnostic methods for triple-negative breast cancer
|
|
CA3114024A1
(en)
|
2018-09-26 |
2020-04-02 |
Merck Patent Gmbh |
Combination of a pd-1 antagonist, an atr inhibitor and a platinating agent for the treatment of cancer
|
|
CN113454070A
(zh)
|
2018-09-30 |
2021-09-28 |
豪夫迈·罗氏有限公司 |
噌啉化合物及用于hpk1依赖性疾患诸如癌症的治疗
|
|
EP3860578A1
(en)
|
2018-10-01 |
2021-08-11 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
TW202024053A
(zh)
|
2018-10-02 |
2020-07-01 |
美商建南德克公司 |
異喹啉化合物及其用途
|
|
TW202023558A
(zh)
|
2018-10-03 |
2020-07-01 |
美商建南德克公司 |
8-胺基異喹啉化合物及其用途
|
|
JP7612571B2
(ja)
|
2018-10-03 |
2025-01-14 |
ゼンコア インコーポレイテッド |
Ｉｌ－１２ヘテロ二量体ｆｃ－融合タンパク質
|
|
US20210395392A1
(en)
|
2018-10-09 |
2021-12-23 |
Bristol-Myers Squibb Company |
Anti-mertk antibodies for treating cancer
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
CR20210239A
(es)
|
2018-10-12 |
2021-12-15 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas
|
|
WO2020079581A1
(en)
|
2018-10-16 |
2020-04-23 |
Novartis Ag |
Tumor mutation burden alone or in combination with immune markers as biomarkers for predicting response to targeted therapy
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
WO2020081767A1
(en)
|
2018-10-18 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
EP3867410A4
(en)
|
2018-10-18 |
2022-07-13 |
MedImmune, LLC |
METHODS OF DETERMINING A TREATMENT FOR CANCER PATIENTS
|
|
EP3866850B1
(en)
|
2018-10-19 |
2024-07-24 |
Bristol-Myers Squibb Company |
Combination therapy for melanoma
|
|
US20210324081A1
(en)
|
2018-10-22 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing
|
|
CN112912403A
(zh)
|
2018-10-23 |
2021-06-04 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
US11564995B2
(en)
|
2018-10-29 |
2023-01-31 |
Wisconsin Alumni Research Foundation |
Peptide-nanoparticle conjugates
|
|
KR20210084552A
(ko)
|
2018-10-29 |
2021-07-07 |
위스콘신 얼럼나이 리서어치 화운데이션 |
향상된 암 면역요법을 위한 면역관문 억제제와 복합체화된 덴드리틱 폴리머
|
|
US12264189B2
(en)
|
2018-10-31 |
2025-04-01 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
WO2020092736A1
(en)
|
2018-10-31 |
2020-05-07 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
WO2020089811A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
EP3890773A4
(en)
|
2018-11-08 |
2022-11-09 |
Orionis Biosciences, Inc. |
MODULATION OF DENDRITIC CELL LINES
|
|
BR112021008288A2
(pt)
|
2018-11-09 |
2021-08-10 |
Jiangsu Hengrui Medicine Co., Ltd. |
composição farmacêutica de proteína de fusão do receptor tgf-ss e uso da mesma
|
|
TW202028222A
(zh)
|
2018-11-14 |
2020-08-01 |
美商Ionis製藥公司 |
Foxp3表現之調節劑
|
|
SG11202105078XA
(en)
|
2018-11-14 |
2021-06-29 |
Bayer Ag |
Pharmaceutical combination of anti-ceacam6 and either anti-pd-1 or anti-pd-l1 antibodies for the treatment of cancer
|
|
CA3119742A1
(en)
|
2018-11-16 |
2020-05-22 |
Arqule, Inc. |
Pharmaceutical combination for treatment of cancer
|
|
PE20211284A1
(es)
|
2018-11-16 |
2021-07-19 |
Bristol Myers Squibb Co |
Anticuerpos anti-nkg2a y usos de los mismos
|
|
EP3880231A1
(en)
|
2018-11-16 |
2021-09-22 |
NeoImmuneTech, Inc. |
Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
|
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
|
EP3883964A1
(en)
|
2018-11-20 |
2021-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
CN113056288A
(zh)
|
2018-11-20 |
2021-06-29 |
康奈尔大学 |
放射性核素的大环配合物及其在癌症的放射治疗中的应用
|
|
EP3886842A1
(en)
|
2018-11-26 |
2021-10-06 |
Debiopharm International SA |
Combination treatment of hiv infections
|
|
EP3887397A1
(en)
|
2018-11-28 |
2021-10-06 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
EP3887823B1
(en)
|
2018-11-28 |
2024-01-17 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and kit for assaying lytic potential of immune effector cells
|
|
JP7406556B2
(ja)
|
2018-11-30 |
2023-12-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
Ｈｉｖ療法に有用な化合物
|
|
US20220162705A1
(en)
|
2018-11-30 |
2022-05-26 |
Gbg Forschungs Gmbh |
Method for predicting the response to cancer immunotherapy in cancer patients
|
|
KR102835299B1
(ko)
|
2018-12-04 |
2025-07-18 |
브리스톨-마이어스 스큅 컴퍼니 |
다중 동위원소체 반응 모니터링에 의한 샘플내 보정 곡선을 사용한 분석 방법
|
|
EP3890749B1
(en)
|
2018-12-04 |
2025-10-29 |
Sumitomo Pharma America, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
MX2021006578A
(es)
|
2018-12-05 |
2021-07-07 |
Genentech Inc |
Procedimientos de diagnostico y composiciones para la inmunoterapia contra el cancer.
|
|
WO2020115262A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
TWI856047B
(zh)
|
2018-12-19 |
2024-09-21 |
美商信號生物製藥公司 |
多聚體ｔ細胞調節多肽及其使用方法
|
|
WO2020127411A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
|
KR20210104704A
(ko)
|
2018-12-19 |
2021-08-25 |
바이엘 악티엔게젤샤프트 |
항 ceacam6 및 tim3 항체의 제약 조합물
|
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
BR112021011874A2
(pt)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
|
CA3119584A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome
|
|
CA3119582A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1.beta. binding antibodies
|
|
WO2020128613A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
|
JP7737143B2
(ja)
|
2018-12-21 |
2025-09-10 |
エイム・イムノテック・インコーポレイテッド |
がん治療のための組成物および方法
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
|
US20220054524A1
(en)
|
2018-12-21 |
2022-02-24 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
|
AU2019414793A1
(en)
|
2018-12-26 |
2021-06-24 |
Innate Pharma |
Compounds and methods for treatment of head and neck cancer
|
|
AU2019413690A1
(en)
*
|
2018-12-27 |
2021-08-12 |
Gigagen, Inc. |
Anti-PD-L1 binding proteins and methods of use thereof
|
|
WO2020139956A1
(en)
|
2018-12-28 |
2020-07-02 |
Sparx Therapeutics Inc. |
Binding molecules specific for claudin 18.2, compositons and methods thereof, for treatment of cancer and other diseases
|
|
MX2021007860A
(es)
|
2018-12-28 |
2021-10-26 |
Transgene |
Poxvirux deficiente en m2.
|
|
EP3911417B1
(en)
|
2019-01-14 |
2022-10-26 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators , for use in the treatment of cancer
|
|
EP3911642A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
AU2020208193A1
(en)
|
2019-01-14 |
2021-07-29 |
BioNTech SE |
Methods of treating cancer with a PD-1 axis binding antagonist and an RNA vaccine
|
|
US12391675B2
(en)
|
2019-01-14 |
2025-08-19 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
WO2020150113A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
|
ES3011707T3
(en)
|
2019-01-15 |
2025-04-08 |
Inst Nat Sante Rech Med |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
JP7442536B2
(ja)
|
2019-01-30 |
2024-03-04 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ガンを患っている被験体が免疫チェックポイント阻害剤で反応を達成するかを特定するための方法及び組成物
|
|
EP3917964A1
(en)
|
2019-02-01 |
2021-12-08 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments for cancer comprising belantamab mafodotin and an anti ox40 antibody and uses and methods thereof
|
|
WO2020161083A1
(en)
|
2019-02-04 |
2020-08-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
|
EP3921443A1
(en)
|
2019-02-08 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
|
AU2020221247B2
(en)
|
2019-02-12 |
2024-12-12 |
Sumitomo Pharma America, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
WO2020165370A1
(en)
|
2019-02-13 |
2020-08-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20220107320A1
(en)
|
2019-02-15 |
2022-04-07 |
Incelldx, Inc. |
Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
MX2021009967A
(es)
|
2019-02-19 |
2021-11-12 |
Myst Therapeutics Llc |
Metodos para producir celulas t autologas utiles para tratar cancer y composiciones de las mismas.
|
|
SG11202109085YA
(en)
*
|
2019-02-21 |
2021-09-29 |
Eucure Beijing Biopharma Co Ltd |
Anti-pd-l1 antibody and use thereof
|
|
JP7492526B2
(ja)
|
2019-02-27 |
2024-05-29 |
アイオーニス ファーマシューティカルズ， インコーポレーテッド |
Ｍａｌａｔ１発現のモジュレーター
|
|
JP7730761B2
(ja)
|
2019-03-14 |
2025-08-28 |
ジェネンテック， インコーポレイテッド |
抗ＨＥＲ２ ＭＡＢと組み合わせたＨＥＲ２ｘＣＤ３二重特異性抗体によるがんの処置
|
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
|
CA3133460A1
(en)
|
2019-03-22 |
2020-10-01 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprising pkm2 modulators and methods of treatment using the same
|
|
KR20210146348A
(ko)
|
2019-03-28 |
2021-12-03 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
WO2020198676A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
JP2022527192A
(ja)
|
2019-03-29 |
2022-05-31 |
ジェネンテック， インコーポレイテッド |
細胞表面タンパク質相互作用のモジュレーター並びにそれに関する方法及び組成物
|
|
MX2021011608A
(es)
|
2019-03-29 |
2021-12-10 |
Myst Therapeutics Llc |
Metodos ex vivo para producir celulas t terapeuticas y composiciones y metodos afines.
|
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
EP3947447A4
(en)
|
2019-04-02 |
2023-01-11 |
Medimmune, LLC |
ANTI-CD73, ANTI-PD-L1 ANTIBODIES AND CHEMOTHERAPY FOR THE TREATMENT OF TUMORS
|
|
CA3131535A1
(en)
|
2019-04-03 |
2020-10-08 |
Targimmune Therapeutics Ag |
Immunotherapy for the treatment of cancer
|
|
WO2020208060A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
BR112021020225A2
(pt)
|
2019-04-12 |
2021-12-07 |
Vascular Biogenics Ltd |
Métodos de terapia antitumoral
|
|
WO2020212484A1
(en)
|
2019-04-17 |
2020-10-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
EP3956364A1
(en)
|
2019-04-19 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Anti-mertk antibodies and their methods of use
|
|
CN113784981B
(zh)
|
2019-04-23 |
2025-01-28 |
先天制药公司 |
Cd73阻断抗体
|
|
EP3963109A1
(en)
|
2019-04-30 |
2022-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2020223233A1
(en)
|
2019-04-30 |
2020-11-05 |
Genentech, Inc. |
Prognostic and therapeutic methods for colorectal cancer
|
|
WO2020227159A2
(en)
|
2019-05-03 |
2020-11-12 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity
|
|
AU2020270376A1
(en)
|
2019-05-03 |
2021-10-07 |
Genentech, Inc. |
Methods of treating cancer with an anti-PD-L1 antibody
|
|
EP3965816A1
(en)
|
2019-05-06 |
2022-03-16 |
MedImmune Limited |
Combination of monalizumab, durvalumab, chemotherapy and bevacizumab or cetuximab for the treatment of colorectal cancer
|
|
US20220251079A1
(en)
|
2019-05-16 |
2022-08-11 |
Stingthera, Inc. |
Benzo[b][1,8]naphthyridine acetic acid derivatives and methods of use
|
|
EP3969438A1
(en)
|
2019-05-16 |
2022-03-23 |
Stingthera, Inc. |
Oxoacridinyl acetic acid derivatives and methods of use
|
|
IL266728B
(en)
|
2019-05-19 |
2020-11-30 |
Yeda Res & Dev |
Identification of recurrent mutant neopeptides
|
|
JP2022534889A
(ja)
|
2019-05-24 |
2022-08-04 |
ファイザー・インコーポレイテッド |
Ｃｄｋ阻害剤を使用した組合せ療法
|
|
CN114127315A
(zh)
|
2019-05-30 |
2022-03-01 |
百时美施贵宝公司 |
鉴定适合于免疫肿瘤学(i-o)疗法的受试者的方法
|
|
US20220233691A1
(en)
|
2019-05-30 |
2022-07-28 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
JP2022534967A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
多腫瘍遺伝子シグネチャーおよびその使用
|
|
CN114206926B
(zh)
|
2019-06-10 |
2022-06-17 |
山东博安生物技术股份有限公司 |
抗PDL1和TGFβ的双功能融合蛋白及其用途
|
|
AU2020308053A1
(en)
|
2019-06-26 |
2022-01-20 |
Glaxosmithkline Intellectual Property Development Limited |
IL1RAP binding proteins
|
|
KR20220028075A
(ko)
|
2019-07-03 |
2022-03-08 |
스미토모 다이니폰 파마 온콜로지, 인크. |
티로신 키나제 비-수용체 1 (tnk1) 억제제 및 그의 용도
|
|
US20220356255A1
(en)
|
2019-07-15 |
2022-11-10 |
Capella Bioscience Ltd |
Anti-pd-l1 antibodies
|
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
|
WO2021019526A1
(en)
|
2019-07-29 |
2021-02-04 |
Yeda Research And Development Co. Ltd. |
Methods of treating and diagnosing lung cancer
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
CR20220076A
(es)
|
2019-08-30 |
2022-06-24 |
Agenus Inc |
Anticuerpos anti-cd96 y sus métodos de uso
|
|
JP2022547061A
(ja)
|
2019-09-05 |
2022-11-10 |
アストラゼネカ・アクチエボラーグ |
進展型小細胞肺癌（ｅｓ－ｓｃｌｃ）の治療のための組成物及び方法
|
|
WO2021043961A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing regimen for the treatment of cancer with an anti icos agonistic antibody and chemotherapy
|
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
CN112480253B
(zh)
|
2019-09-12 |
2022-09-20 |
普米斯生物技术(珠海)有限公司 |
一种抗pd-l1纳米抗体及其衍生物和用途
|
|
US12121565B2
(en)
|
2019-09-13 |
2024-10-22 |
Duke University |
Methods of treatment of specific cancers with NLRP3 inhibitors and anti-PD1/PD-L1 antibodies
|
|
US11918649B2
(en)
|
2019-09-18 |
2024-03-05 |
Molecular Templates, Inc. |
PD-L1-binding molecules comprising Shiga toxin a subunit scaffolds
|
|
KR20220081977A
(ko)
|
2019-09-18 |
2022-06-16 |
몰레큘러 템플레이츠, 인코퍼레이션. |
시가 독소 a 서브유닛 스캐폴드를 포함하는 pd-l1 결합분자(pd-l1 binding molecules comprising shiga toxin a subunit scaffolds)
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Ｅｎｔｐｄ２抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
EP4031575A1
(en)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
|
KR20220068242A
(ko)
|
2019-09-20 |
2022-05-25 |
트랜스진 |
Hpv 폴리펩티드 및 il-2를 암호화하는 폭스바이러스와 항-pd-l1 항체의 조합
|
|
JP2022549273A
(ja)
|
2019-09-22 |
2022-11-24 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｌａｇ－３アンタゴニスト治療のための定量的空間プロファイリング
|
|
JP7739269B2
(ja)
|
2019-09-25 |
2025-09-16 |
ブリストル－マイヤーズ スクイブ カンパニー |
がん療法のための複合バイオマーカー
|
|
PE20221110A1
(es)
|
2019-09-27 |
2022-07-11 |
Genentech Inc |
Administracion de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1
|
|
WO2021058711A2
(en)
|
2019-09-27 |
2021-04-01 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding proteins
|
|
WO2021064567A1
(en)
|
2019-09-30 |
2021-04-08 |
Astrazeneca Ab |
Combination treatment for cancer
|
|
EP4023672A1
(en)
*
|
2019-09-30 |
2022-07-06 |
Harbour Biomed (Shanghai) Co., Ltd |
Anti-pd-l1 antigen binding protein, and application thereof
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
US20220354811A1
(en)
|
2019-10-03 |
2022-11-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
|
AU2020358979A1
(en)
|
2019-10-03 |
2022-04-21 |
Xencor, Inc. |
Targeted IL-12 heterodimeric Fc-fusion proteins
|
|
EP4037710A1
(en)
|
2019-10-04 |
2022-08-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
WO2021076574A2
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
EP4045061A4
(en)
|
2019-10-14 |
2024-04-17 |
ARO Biotherapeutics Company |
FIBRONECTIN TYPE III DOMAINS BINDING TO CD137
|
|
US12491255B2
(en)
|
2019-10-14 |
2025-12-09 |
Aro Biotherapeutics Company |
EPCAM binding fibronectin type III domains
|
|
US12380963B2
(en)
|
2019-10-14 |
2025-08-05 |
The Medical College Of Wisconsin, Inc. |
Gene expression signature of hyperprogressive disease (HPD) in patients after anti-PD-1 immunotherapy
|
|
CA3157889A1
(en)
|
2019-10-17 |
2021-04-22 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
|
JP2022553306A
(ja)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
Ｔｉｍ－３阻害剤およびその使用
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
WO2021079958A1
(ja)
|
2019-10-25 |
2021-04-29 |
第一三共株式会社 |
抗ｇａｒｐ抗体と免疫調節剤の組み合わせ
|
|
US20240122938A1
(en)
|
2019-10-29 |
2024-04-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating uveal melanoma
|
|
US20220387529A1
(en)
|
2019-11-04 |
2022-12-08 |
Duke University |
Treatment for primary and metastatic cancer
|
|
JP2023500506A
(ja)
|
2019-11-04 |
2023-01-06 |
アストラゼネカ・アクチエボラーグ |
癌を治療するための組み合わせ療法
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
JP2022553803A
(ja)
|
2019-11-06 |
2022-12-26 |
ジェネンテック， インコーポレイテッド |
血液がんの処置のための診断方法及び治療方法
|
|
EP4055609A1
(en)
|
2019-11-07 |
2022-09-14 |
Oncxerna Therapeutics, Inc. |
Classification of tumor microenvironments
|
|
CN115942973A
(zh)
|
2019-11-08 |
2023-04-07 |
百时美施贵宝公司 |
用于黑色素瘤的lag-3拮抗剂疗法
|
|
TWI895295B
(zh)
|
2019-11-12 |
2025-09-01 |
美商方得生醫療公司 |
偵測編碼新生抗原之融合基因之方法
|
|
TW202130618A
(zh)
|
2019-11-13 |
2021-08-16 |
美商建南德克公司 |
治療性化合物及使用方法
|
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
|
WO2021102343A1
(en)
|
2019-11-22 |
2021-05-27 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Solid dose pharmaceutical composition
|
|
EP4066852A4
(en)
|
2019-11-27 |
2024-05-22 |
NEC Corporation |
PHARMACEUTICAL COMPOSITION
|
|
CN115023270A
(zh)
|
2019-11-27 |
2022-09-06 |
迈斯特治疗公司 |
使用调节剂产生肿瘤反应性t细胞组合物的方法
|
|
US20230114107A1
(en)
|
2019-12-17 |
2023-04-13 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
|
WO2021119753A1
(en)
|
2019-12-18 |
2021-06-24 |
Ctxt Pty Limited |
Compounds
|
|
WO2021123243A1
(en)
|
2019-12-19 |
2021-06-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
|
US20230089255A1
(en)
|
2019-12-19 |
2023-03-23 |
Bristol-Myers Squibb Company |
Combinations of dgk inhibitors and checkpoint antagonists
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
JP7573622B2
(ja)
|
2020-01-10 |
2024-10-25 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
Ｎｌｒｐ３モジュレーター
|
|
EP4090770A1
(en)
|
2020-01-17 |
2022-11-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
KR20220128389A
(ko)
|
2020-01-17 |
2022-09-20 |
노파르티스 아게 |
골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물
|
|
EP4093772A1
(en)
*
|
2020-01-21 |
2022-11-30 |
Bolt Biotherapeutics, Inc. |
Anti-pd-l1 antibodies
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021152495A1
(en)
|
2020-01-28 |
2021-08-05 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
WO2021154073A1
(en)
|
2020-01-29 |
2021-08-05 |
Merus N.V. |
Means and method for modulating immune cell engaging effects.
|
|
EP4097130A1
(en)
|
2020-01-30 |
2022-12-07 |
Ona Therapeutics S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
CN115397459A
(zh)
|
2020-01-31 |
2022-11-25 |
基因泰克公司 |
用pd-1轴结合拮抗剂和rna疫苗诱导新表位特异性t细胞的方法
|
|
US20230072528A1
(en)
|
2020-02-05 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｉｌ－１０およびその使用
|
|
JP2023513553A
(ja)
|
2020-02-07 |
2023-03-31 |
エイアイ・セラピューティクス・インコーポレーテッド |
抗ウイルス性組成物および使用の方法
|
|
KR20220144821A
(ko)
|
2020-02-21 |
2022-10-27 |
마크로제닉스, 인크. |
Cd137 결합 분자 및 그것의 용도
|
|
HUE062777T2
(hu)
|
2020-02-26 |
2023-12-28 |
Vir Biotechnology Inc |
SARS-CoV-2 elleni antitestek
|
|
IL295990A
(en)
|
2020-02-27 |
2022-11-01 |
Myst Therapeutics Llc |
Methods for in vitro enrichment and expansion of tumor-reactive t cells and preparations related thereto
|
|
WO2021174045A1
(en)
|
2020-02-28 |
2021-09-02 |
Bristol-Myers Squibb Company |
Radiolabeled fibronectin based scaffolds and antibodies and theranostic uses thereof
|
|
EP4110955A1
(en)
|
2020-02-28 |
2023-01-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
|
MX2022011050A
(es)
|
2020-03-06 |
2022-12-15 |
Ona Therapeutics S L |
Anticuerpos anti-cd36 y su uso para tratar cancer.
|
|
US20230089536A1
(en)
|
2020-03-06 |
2023-03-23 |
Celgene Quanticel Research, Inc. |
Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
|
|
WO2021177980A1
(en)
|
2020-03-06 |
2021-09-10 |
Genentech, Inc. |
Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
|
|
EP3878446A1
(en)
|
2020-03-09 |
2021-09-15 |
Universite De Geneve |
Hsd11b1 inhibitors for use in immunotherapy and uses thereof
|
|
WO2021183428A1
(en)
|
2020-03-09 |
2021-09-16 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
KR20220157446A
(ko)
|
2020-03-23 |
2022-11-29 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하기 위한 항-ccr8 항체
|
|
EP4045533B1
(en)
|
2020-03-26 |
2023-11-15 |
Vanderbilt University |
Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
|
|
US20230122364A1
(en)
*
|
2020-03-27 |
2023-04-20 |
Vanderbilt University |
HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)
|
|
EP4127724A1
(en)
|
2020-04-03 |
2023-02-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
WO2021205444A1
(en)
|
2020-04-06 |
2021-10-14 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing cancer and predicting responsiveness to therapy
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
CA3175490A1
(en)
|
2020-04-14 |
2021-10-21 |
Glaxosmithkline Intellectual Property Limited |
Combination treatment for cancer based upon an icos antibody and a pd-l1 antibody tgf-beta-receptor fusion protein
|
|
KR20230037069A
(ko)
|
2020-04-22 |
2023-03-15 |
이오반스 바이오테라퓨틱스, 인크. |
환자-특이적 면역요법을 위해 세포의 제조를 조정하기 위한 시스템 및 방법
|
|
US12264190B2
(en)
|
2020-04-24 |
2025-04-01 |
Astrazeneca Ab |
Compositions and methods of treating cancer with chimeric antigen receptors
|
|
BR112022021789A2
(pt)
|
2020-04-27 |
2023-03-07 |
Twist Bioscience Corp |
Bibliotecas de ácido nucléico variantes para coronavírus
|
|
JP2023523450A
(ja)
|
2020-04-28 |
2023-06-05 |
ジェネンテック， インコーポレイテッド |
非小細胞肺がん免疫療法のための方法及び組成物
|
|
WO2021224215A1
(en)
|
2020-05-05 |
2021-11-11 |
F. Hoffmann-La Roche Ag |
Predicting response to pd-1 axis inhibitors
|
|
AU2021272895A1
(en)
|
2020-05-12 |
2022-09-22 |
Cue Biopharma, Inc. |
Multimeric T-cell modulatory polypeptides and methods of use thereof
|
|
WO2021228988A1
(en)
|
2020-05-12 |
2021-11-18 |
Astrazeneca Ab |
Biomarkers for predicting overall survival in recurrent/metastatic head and neck squamous cell carcinoma
|
|
JP7387912B2
(ja)
|
2020-05-12 |
2023-11-28 |
アストラゼネカ・アクチエボラーグ |
免疫チェックポイント阻害剤抗体を使用した癌の処置のための方法及び組み合わせ
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
EP4153783A1
(en)
|
2020-05-21 |
2023-03-29 |
Astrazeneca AB |
Tumor mutational burden associated with sensitivity to immunotherapy in locally advanced or metastatic urothelial carcinoma
|
|
EP4157343A2
(en)
|
2020-05-26 |
2023-04-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
JP2023528071A
(ja)
|
2020-06-03 |
2023-07-03 |
エムヴィ バイオセラピューティクス エスエー |
Ａｔｐ加水分解酵素と免疫チェックポイントモジュレーターとの組合せ、並びにその使用
|
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
|
WO2021252977A1
(en)
|
2020-06-12 |
2021-12-16 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
|
MX2022015877A
(es)
|
2020-06-16 |
2023-01-24 |
Genentech Inc |
Metodos y composiciones para tratar cancer de mama triple negativo.
|
|
IL298946A
(en)
|
2020-06-18 |
2023-02-01 |
Genentech Inc |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CA3184366A1
(en)
|
2020-06-29 |
2022-01-06 |
Darby Rye Schmidt |
Viruses engineered to promote thanotransmission and their use in treating cancer
|
|
US20230250173A1
(en)
|
2020-07-01 |
2023-08-10 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
|
AU2021306613A1
(en)
|
2020-07-07 |
2023-02-02 |
BioNTech SE |
Therapeutic RNA for HPV-positive cancer
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
WO2022023379A1
(en)
|
2020-07-28 |
2022-02-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for preventing and treating a cancer
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP4196612A1
(en)
|
2020-08-12 |
2023-06-21 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
CN116194480A
(zh)
|
2020-08-13 |
2023-05-30 |
百时美施贵宝公司 |
将il-2重定向到目的靶细胞的方法
|
|
KR20230058442A
(ko)
|
2020-08-28 |
2023-05-03 |
브리스톨-마이어스 스큅 컴퍼니 |
간세포성 암종에 대한 lag-3 길항제 요법
|
|
BR112023003553A2
(pt)
|
2020-08-31 |
2023-04-04 |
Bristol Myers Squibb Co |
Assinatura de localização celular e imunoterapia
|
|
CN114106190B
(zh)
|
2020-08-31 |
2025-04-08 |
普米斯生物技术(珠海)有限公司 |
一种抗vegf/pd-l1双特异性抗体及其用途
|
|
EP4211149A4
(en)
|
2020-09-09 |
2024-10-09 |
Cue Biopharma, Inc. |
MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF
|
|
TW202227126A
(zh)
|
2020-09-14 |
2022-07-16 |
德商百靈佳殷格翰國際股份有限公司 |
異源初免加強疫苗
|
|
US20230374064A1
(en)
|
2020-10-05 |
2023-11-23 |
Bristol-Myers Squibb Company |
Methods for concentrating proteins
|
|
WO2022076596A1
(en)
|
2020-10-06 |
2022-04-14 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
US20230372384A1
(en)
|
2020-10-08 |
2023-11-23 |
Targimmune Therapeutics Ag |
Immunotherapy for the treatment of cancer
|
|
AU2021360175A1
(en)
|
2020-10-12 |
2023-06-15 |
Astrazeneca Ab |
Adjuvant durvalumab in combination with chemotherapy for treatment of cancer
|
|
WO2022084210A1
(en)
|
2020-10-20 |
2022-04-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1 axis binding antagonists and lrrk2 inhitibors
|
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Ｐｅｇ結合抗ｍｅｒｔｋ抗體及其使用方法
|
|
JP2023548051A
(ja)
|
2020-10-23 |
2023-11-15 |
ブリストル－マイヤーズ スクイブ カンパニー |
肺がんのためのｌａｇ－３アンタゴニスト療法
|
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
JP2023549678A
(ja)
|
2020-10-28 |
2023-11-29 |
イケナ オンコロジー， インコーポレイテッド |
ＡＨＲ阻害剤のＰＤｘ阻害剤またはドキソルビシンとの組み合わせ
|
|
US20240025993A1
(en)
|
2020-11-06 |
2024-01-25 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
KR20230107260A
(ko)
|
2020-11-12 |
2023-07-14 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
Sars-cov-2 스파이크 단백질의 수용체-결합 도메인에 접합되거나 융합된 항체, 및 백신 목적을 위한 이의 용도
|
|
WO2022103904A1
(en)
|
2020-11-13 |
2022-05-19 |
Genentech, Inc. |
Methods and compositions comprising a krasg12c inhibitor and a pd-l1 binding antagonist for treating lung cancer
|
|
US20230416830A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
EP4244392A1
(en)
|
2020-11-16 |
2023-09-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
KR20230117162A9
(ko)
|
2020-12-02 |
2024-03-21 |
제넨테크, 인크. |
신보조 및 보조 요로상피 암종 요법을 위한 방법 및 조성물
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Ａｌｋ﹘５抑制劑和彼之用途
|
|
EP4262858A1
(en)
|
2020-12-16 |
2023-10-25 |
Molecular Templates, Inc. |
Clinical methods for use of a pd-l1-binding molecule comprising a shiga toxin effector
|
|
JP2024500847A
(ja)
|
2020-12-18 |
2024-01-10 |
センチュリー セラピューティクス，インコーポレイテッド |
適合可能な受容体特異性を有するキメラ抗原受容体システム
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
JP2024501029A
(ja)
|
2020-12-28 |
2024-01-10 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｐｄ１／ｐｄ－ｌ１抗体の皮下投与
|
|
EP4566674A3
(en)
|
2020-12-28 |
2025-08-06 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
TW202227486A
(zh)
*
|
2021-01-04 |
2022-07-16 |
大陸商上海翰森生物醫藥科技有限公司 |
一種抗erbb3受體的抗體或其抗原結合片段及其醫藥用途
|
|
WO2022148736A1
(en)
|
2021-01-05 |
2022-07-14 |
Transgene |
Vectorization of muc1 t cell engager
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗ｃｄ７３及び抗ｅｎｔｐｄ２抗体のための投与方式並びにその使用
|
|
EP4284919A1
(en)
|
2021-01-29 |
2023-12-06 |
Iovance Biotherapeutics, Inc. |
Methods of making modified tumor infiltrating lymphocytes and their use in adoptive cell therapy
|
|
US20240139198A1
(en)
|
2021-02-10 |
2024-05-02 |
Curon Biopharmaceutical (Shanghai) Co., Limited |
Method and combination for treating tumors
|
|
CA3209869A1
(en)
*
|
2021-02-26 |
2022-09-01 |
Fred Hutchinson Cancer Center |
Protective antibodies against respiratory viral infections
|
|
AU2022230795B2
(en)
|
2021-03-02 |
2025-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Substituted pyridines as dnmt1 inhibitors
|
|
WO2022194908A1
(en)
|
2021-03-17 |
2022-09-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
CN117321418A
(zh)
|
2021-03-18 |
2023-12-29 |
诺华股份有限公司 |
癌症生物标志物及其使用方法
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
AU2022245322A1
(en)
|
2021-03-25 |
2023-10-05 |
Oncxerna Therapeutics, Inc. |
Targeted therapies in cancer
|
|
EP4313057A1
(en)
|
2021-03-26 |
2024-02-07 |
Astrazeneca AB |
Combination treatments for melanoma
|
|
AU2022246593A1
(en)
|
2021-03-29 |
2023-10-12 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
EP4314060A1
(en)
|
2021-03-31 |
2024-02-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Antigen binding proteins and combinations thereof
|
|
CA3214085A1
(en)
|
2021-03-31 |
2022-10-06 |
Darby Rye Schmidt |
Thanotransmission polypeptides and their use in treating cancer
|
|
WO2022212876A1
(en)
|
2021-04-02 |
2022-10-06 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
AU2022254104A1
(en)
|
2021-04-08 |
2023-10-26 |
Nurix Therapeutics, Inc. |
Combination therapies with cbl-b inhibitor compounds
|
|
JP2024513505A
(ja)
|
2021-04-09 |
2024-03-25 |
ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド |
腫瘍を治療するための組成物及び方法
|
|
US20240182572A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains
|
|
JP2024513246A
(ja)
|
2021-04-09 |
2024-03-22 |
ジェネンテック， インコーポレイテッド |
Ｒａｆ阻害剤及びｐｄ－１軸阻害剤を用いた併用治療
|
|
JP2024515263A
(ja)
|
2021-04-09 |
2024-04-08 |
オーエスイー・イミュノセラピューティクス |
改善された特性を有する二機能性分子のための新規足場構造
|
|
CA3213079A1
(en)
|
2021-04-13 |
2022-10-20 |
Kristin Lynne ANDREWS |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
US20240228659A1
(en)
|
2021-04-14 |
2024-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
|
JP2024517610A
(ja)
|
2021-04-14 |
2024-04-23 |
アロ・バイオセラピューティクス・カンパニー |
Ｃｄ７１に結合するフィブロネクチンｉｉｉ型ドメイン
|
|
EP4323008A1
(en)
|
2021-04-14 |
2024-02-21 |
ARO Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
WO2022226539A1
(en)
*
|
2021-04-23 |
2022-10-27 |
Immunome, Inc. |
Methods of administering antibodies against sars-cov-2 spike protein
|
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
|
WO2022229966A1
(en)
|
2021-04-29 |
2022-11-03 |
Yeda Research And Development Co. Ltd. |
T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same
|
|
WO2022232503A1
(en)
|
2021-04-30 |
2022-11-03 |
Genentech, Inc. |
Therapeutic and diagnostic methods and compositions for cancer
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243378A1
(en)
|
2021-05-18 |
2022-11-24 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
CN117396222A
(zh)
|
2021-05-21 |
2024-01-12 |
天津立博美华基因科技有限责任公司 |
药物组合及其用途
|
|
JP2024521105A
(ja)
|
2021-05-24 |
2024-05-28 |
アストラゼネカ・アクチエボラーグ |
肺癌の処置用組成物及び方法
|
|
CA3218786A1
(en)
|
2021-05-25 |
2022-12-01 |
Lifei HOU |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
CA3220191A1
(en)
|
2021-05-26 |
2022-12-01 |
Tania Crombet Ramos |
Use of therapeutic compositions for the treatment of patients with tumours of epithelial origin
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
CA3224374A1
(en)
|
2021-06-29 |
2023-01-05 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
|
IL309662A
(en)
|
2021-07-02 |
2024-02-01 |
Univ Yale |
Compositions and methods for treating cancers
|
|
TW202309078A
(zh)
|
2021-07-02 |
2023-03-01 |
美商建南德克公司 |
治療癌症之方法及組成物
|
|
US20240316005A1
(en)
|
2021-07-05 |
2024-09-26 |
Institut National de la Santé et de la Recherche Médicale |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
JP2024525758A
(ja)
|
2021-07-13 |
2024-07-12 |
ビオンテック・ソシエタス・エウロパエア |
がんのための併用療法におけるｃｄ４０およびｃｄ１３７に対する多重特異性結合剤
|
|
WO2023010094A2
(en)
|
2021-07-28 |
2023-02-02 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
CN117715936A
(zh)
|
2021-07-28 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的方法和组合物
|
|
US20250206836A1
(en)
|
2021-07-30 |
2025-06-26 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
WO2023034864A1
(en)
|
2021-08-31 |
2023-03-09 |
Yale University |
Compositions and methods for treating cancers
|
|
IL310773A
(en)
|
2021-09-02 |
2024-04-01 |
Deutsches Krebsforschungszentrum Stiftung Des ?Ffentlichen Rechts |
Anti-CECAM6 antibodies with reduced side effects
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法
|
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
JP2024539164A
(ja)
|
2021-10-21 |
2024-10-28 |
杭州阿諾生物医薬科技有限公司 |
融合ポリペプチドの一種とその使用
|
|
EP4423249A1
(en)
|
2021-10-28 |
2024-09-04 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
KR20240099362A
(ko)
|
2021-10-29 |
2024-06-28 |
브리스톨-마이어스 스큅 컴퍼니 |
혈액암에 대한 lag-3 길항제 요법
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
WO2023078900A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
EP4433504A1
(en)
|
2021-11-17 |
2024-09-25 |
Institut National de la Santé et de la Recherche Médicale |
Universal sarbecovirus vaccines
|
|
TW202332429A
(zh)
|
2021-11-24 |
2023-08-16 |
美商建南德克公司 |
治療性化合物及其使用方法
|
|
TW202340212A
(zh)
|
2021-11-24 |
2023-10-16 |
美商建南德克公司 |
治療性化合物及其使用方法
|
|
CA3240558A1
(en)
|
2021-12-16 |
2023-06-22 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
US20250041261A1
(en)
|
2021-12-21 |
2025-02-06 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating melanoma
|
|
WO2023129438A1
(en)
|
2021-12-28 |
2023-07-06 |
Wisconsin Alumni Research Foundation |
Hydrogel compositions for use for depletion of tumor associated macrophages
|
|
WO2023137161A1
(en)
|
2022-01-14 |
2023-07-20 |
Amgen Inc. |
Triple blockade of tigit, cd112r, and pd-l1
|
|
JP2025503962A
(ja)
|
2022-01-26 |
2025-02-06 |
ブリストル－マイヤーズ スクイブ カンパニー |
肝細胞がんのための併用療法
|
|
CA3243419A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
CYTOKINE-ASSOCIATED TUMOR-INFILTRATING LYMPHOCYTE COMPOSITIONS AND PROCESSES
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
US20250179174A1
(en)
|
2022-02-25 |
2025-06-05 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
MX2024010773A
(es)
|
2022-03-03 |
2024-09-10 |
Pfizer |
Anticuerpos multiespecificos y usos de estos.
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
CN118786346A
(zh)
|
2022-03-07 |
2024-10-15 |
阿斯利康(瑞典)有限公司 |
用于预测患者对免疫疗法的应答的方法
|
|
AU2023230110A1
(en)
|
2022-03-08 |
2024-10-24 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
WO2023174210A1
(en)
|
2022-03-14 |
2023-09-21 |
Laekna Limited |
Combination treatment for cancer
|
|
JPWO2023176881A1
(hu)
|
2022-03-16 |
2023-09-21 |
|
|
|
JP2025509749A
(ja)
|
2022-03-18 |
2025-04-11 |
ブリストル－マイヤーズ スクイブ カンパニー |
ポリペプチドの単離方法
|
|
CN119072332A
(zh)
|
2022-03-18 |
2024-12-03 |
阿斯利康(瑞典)有限公司 |
使用抗pd-l1抗体与化学疗法的组合治疗胆道癌的方法
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
CA3246312A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
WO2023196964A1
(en)
|
2022-04-08 |
2023-10-12 |
Bristol-Myers Squibb Company |
Machine learning identification, classification, and quantification of tertiary lymphoid structures
|
|
WO2023201291A1
(en)
|
2022-04-13 |
2023-10-19 |
Genentech, Inc. |
Pharmaceutical compositions of mosunetuzumab and methods of use
|
|
KR20250004768A
(ko)
|
2022-04-13 |
2025-01-08 |
제넨테크, 인크. |
치료 단백질의 약학적 조성물 및 사용 방법
|
|
EP4507704A1
(en)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
AU2022458320A1
(en)
|
2022-05-11 |
2024-11-28 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
KR20250012585A
(ko)
|
2022-05-12 |
2025-01-24 |
제넨테크, 인크. |
Shp2 억제제와 pd-l1 결합 길항제를 포함하는 방법 및 조성물
|
|
US20250340641A1
(en)
|
2022-05-18 |
2025-11-06 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
CA3256230A1
(en)
|
2022-05-24 |
2023-11-30 |
Daiichi Sankyo Company, Limited |
DOSAGE REGIMEN OF AN ANTI-CDH6 ANTIBODY-DRUG CONJUGATE
|
|
AR129423A1
(es)
|
2022-05-27 |
2024-08-21 |
Viiv Healthcare Co |
Compuestos útiles en la terapia contra el hiv
|
|
WO2023235415A1
(en)
|
2022-06-01 |
2023-12-07 |
Genentech, Inc. |
Method to identify a patient with an increased likelihood of chemotherapy-induced peripheral neuropathy
|
|
US20250332252A1
(en)
|
2022-06-02 |
2025-10-30 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
KR20250022049A
(ko)
|
2022-06-07 |
2025-02-14 |
제넨테크, 인크. |
항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법
|
|
WO2024003241A1
(en)
|
2022-06-30 |
2024-01-04 |
Astrazeneca Ab |
Treatment for immuno-oncology resistant subjects with an anti pd-l1 antibody an antisense targeted to stat3 and an inhibitor of ctla-4
|
|
CA3261147A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
CN119923267A
(zh)
|
2022-07-27 |
2025-05-02 |
阿斯利康(瑞典)有限公司 |
表达白介素-12的重组病毒与pd-1/pd-l1抑制剂的组合
|
|
TW202412859A
(zh)
|
2022-07-28 |
2024-04-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及雙特異性檢查點抑制劑之組合
|
|
EP4565271A2
(en)
*
|
2022-08-05 |
2025-06-11 |
HBM Alpha Therapeutics, Inc. |
Anti-corticotropin-releasing hormone antibodies and polycystic ovary syndrome
|
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
|
WO2024040175A1
(en)
|
2022-08-18 |
2024-02-22 |
Pulmatrix Operating Company, Inc. |
Methods for treating cancer using inhaled angiogenesis inhibitor
|
|
CN120153254A
(zh)
|
2022-09-01 |
2025-06-13 |
基因泰克公司 |
膀胱癌的治疗和诊断方法
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
WO2024054992A1
(en)
|
2022-09-09 |
2024-03-14 |
Bristol-Myers Squibb Company |
Methods of separating chelator
|
|
WO2024052514A1
(en)
|
2022-09-09 |
2024-03-14 |
Astrazeneca Ab |
Compositions and methods for treating advanced solid tumors
|
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
|
WO2024069009A1
(en)
|
2022-09-30 |
2024-04-04 |
Alentis Therapeutics Ag |
Treatment of drug-resistant hepatocellular carcinoma
|
|
EP4599088A1
(en)
|
2022-10-05 |
2025-08-13 |
Genentech, Inc. |
Methods and compositions for classifying and treating lung cancer
|
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
|
WO2024077095A1
(en)
|
2022-10-05 |
2024-04-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating bladder cancer
|
|
EP4606384A1
(en)
|
2022-10-19 |
2025-08-27 |
Astellas Pharma, Inc. |
Use of anti-cldn4-anti-cd137 bispecific antibody combined with pd-1 signal inhibitor for cancer treatment
|
|
WO2024084034A1
(en)
|
2022-10-21 |
2024-04-25 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
|
EP4608390A1
(en)
|
2022-10-24 |
2025-09-03 |
Cancer Research Technology Limited |
Tumour sensitisation to checkpoint inhibitors with redox status modifier
|
|
WO2024089417A1
(en)
|
2022-10-24 |
2024-05-02 |
Memorial Sloan-Kettering Cancer Center |
Tumour stratification for responsiveness to an immune checkpoint inhibitor
|
|
KR20250093336A
(ko)
|
2022-10-25 |
2025-06-24 |
제넨테크, 인크. |
다발성 골수종에 대한 치료 및 진단 방법
|
|
KR20250099224A
(ko)
|
2022-11-01 |
2025-07-01 |
하이델베르크 파마 리서치 게엠베하 |
항-gucy2c 항체 및 이의 용도
|
|
WO2024097328A1
(en)
|
2022-11-03 |
2024-05-10 |
Incyte Corporation |
Combination therapies comprising an anti-gitr antibody for treating cancers
|
|
EP4623072A2
(en)
|
2022-11-21 |
2025-10-01 |
Iovance Biotherapeutics, Inc. |
Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
|
|
KR20250113504A
(ko)
|
2022-11-29 |
2025-07-25 |
애들레이 노르티 바이오파마 컴퍼니 리미티드 |
융합 폴리펩타이드 및 그 용도
|
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
|
EP4626922A2
(en)
|
2022-12-01 |
2025-10-08 |
Innate Pharma |
Compositions and methods for neoadjuvant treatment in cancer comprising anti-cd39 antibodies
|
|
US20250340648A1
(en)
|
2022-12-01 |
2025-11-06 |
Medimmune Limited |
Combination therapy for treatment of cancer comprising anti-pd-l1 and anti-cd73 antibodies
|
|
KR20250120305A
(ko)
|
2022-12-14 |
2025-08-08 |
아스텔라스 파마 유럽 비.브이. |
Cldn18.2 및 cd3에 결합하는 2중 특이성 결합제와 면역 체크포인트 저해제를 수반한 조합 요법
|
|
EP4637807A2
(en)
|
2022-12-20 |
2025-10-29 |
Genentech Inc. |
Methods of treating pancreatic cancer with a pd-1 axis binding antagonist and an rna vaccine
|
|
KR20250123912A
(ko)
|
2022-12-21 |
2025-08-18 |
브리스톨-마이어스 스큅 컴퍼니 |
폐암에 대한 병용 요법
|
|
US20240269251A1
(en)
|
2023-01-09 |
2024-08-15 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
WO2024150177A1
(en)
|
2023-01-11 |
2024-07-18 |
Advesya |
Treatment methods for solid tumors
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
EP4649173A1
(en)
|
2023-01-13 |
2025-11-19 |
Akrivia Biomedics Limited |
Method of profiling diseases
|
|
EP4658310A1
(en)
|
2023-01-30 |
2025-12-10 |
Kymab Limited |
Antibodies
|
|
EP4658687A1
(en)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024192051A1
(en)
|
2023-03-13 |
2024-09-19 |
Turnstone Biologics Corp. |
Composition of selected tumor infiltrating lymphocytes and related methods of producing and using the same
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024200571A1
(en)
|
2023-03-28 |
2024-10-03 |
Institut National de la Santé et de la Recherche Médicale |
Method for discriminating mono-immunotherapy from combined immunotherapy in cancers
|
|
CN120917143A
(zh)
|
2023-03-29 |
2025-11-07 |
第一三共株式会社 |
抗cd25抗体及抗cd25抗体-药物偶联物
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
AU2024250324A1
(en)
|
2023-04-14 |
2025-11-27 |
Astrazeneca Ab |
Treatment of non-small cell lung cancer
|
|
WO2024228167A1
(en)
|
2023-05-03 |
2024-11-07 |
Iox Therapeutics Inc. |
Inkt cell modulator liposomal compositions and methods of use
|
|
AU2024270495A1
(en)
|
2023-05-05 |
2025-10-09 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2024231384A1
(en)
|
2023-05-10 |
2024-11-14 |
Institut National de la Santé et de la Recherche Médicale |
Compositions for treating senescence related disease
|
|
WO2024233646A1
(en)
|
2023-05-10 |
2024-11-14 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
TW202509074A
(zh)
|
2023-05-17 |
2025-03-01 |
瑞典商阿斯特捷利康公司 |
用於治療子宮頸癌之方法及組合
|
|
WO2024245951A1
(en)
|
2023-05-26 |
2024-12-05 |
Institut National de la Santé et de la Recherche Médicale |
Combination of slc8a1 inhibitor and mitochondria-targeted antioxidant for treating melanoma
|
|
WO2024246835A1
(en)
|
2023-05-31 |
2024-12-05 |
Astrazeneca Ab |
Methods, compositions, and combinations for the treatment of ovarian cancer
|
|
WO2024256635A1
(en)
|
2023-06-15 |
2024-12-19 |
Institut National de la Santé et de la Recherche Médicale |
Dpm1 inhibitor for treating cancer
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024261239A1
(en)
|
2023-06-23 |
2024-12-26 |
Imcheck Therapeutics |
Bispecific antibodies targeting btn3a and the pd-1/pd-l1 inhibitory axis
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
WO2025006811A1
(en)
|
2023-06-27 |
2025-01-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025024257A1
(en)
|
2023-07-21 |
2025-01-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
IL304887A
(en)
|
2023-07-31 |
2025-02-01 |
Yeda Res & Dev |
T-cell receptor directed against RAS neoantigen
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
CN119488588A
(zh)
|
2023-08-17 |
2025-02-21 |
阿斯利康(瑞典)有限公司 |
用于治疗子宫内膜癌的方法、组合物和组合
|
|
WO2025049277A1
(en)
|
2023-08-25 |
2025-03-06 |
Genentech, Inc. |
Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
TW202529802A
(zh)
|
2023-09-22 |
2025-08-01 |
瑞典商阿斯特捷利康公司 |
胃癌和／或胃食管結合部癌的治療
|
|
WO2025073765A1
(en)
|
2023-10-03 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from melanoma
|
|
WO2025080865A1
(en)
|
2023-10-11 |
2025-04-17 |
Turnstone Biologics Corp. |
Combination of tumor infiltrating lymphocytes (til) and low dose radiation
|
|
WO2025078632A1
(en)
|
2023-10-12 |
2025-04-17 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from cancer
|
|
WO2025085404A1
(en)
|
2023-10-16 |
2025-04-24 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treating lung cancer
|
|
WO2025083600A1
(en)
|
2023-10-17 |
2025-04-24 |
Astrazeneca Ab |
Predicting response to neoadjuvant treatment in non-small cell lung cancer
|
|
WO2025085781A1
(en)
|
2023-10-19 |
2025-04-24 |
Genentech, Inc. |
Combinations of il15/il15r alpha heterodimeric fc-fusion proteins and her2xcd3 bispecific antibodies for the treatment of her2-positive cancers
|
|
WO2025096638A2
(en)
|
2023-10-30 |
2025-05-08 |
Turnstone Biologics Corp. |
Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same
|
|
WO2025109597A1
(en)
|
2023-11-22 |
2025-05-30 |
Yeda Research And Development Co. Ltd. |
T cell receptors directed against androgen receptor mutation
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025132479A1
(en)
|
2023-12-18 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Flt3 inhibitor for modulating macrophages polarization
|
|
WO2025132770A1
(en)
|
2023-12-22 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Affitins for the treatment of cancer
|
|
US20250215087A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg depleting agent
|
|
WO2025155607A1
(en)
|
2024-01-16 |
2025-07-24 |
Genentech, Inc. |
Methods of treating urothelial carcinoma with a pd-1 axis binding antagonist and an rna vaccine
|
|
WO2025174933A1
(en)
|
2024-02-14 |
2025-08-21 |
Genentech, Inc. |
Methods for treatment of pancreatic cancer with anti-pd-l1 ab, anti-tigit ab, gemcitabine and nab-placlitaxel
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025210123A1
(en)
|
2024-04-03 |
2025-10-09 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating cancers
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025210571A1
(en)
|
2024-04-05 |
2025-10-09 |
Astrazeneca Ab |
Treatment of limited-stage small-cell lung cancer with pd-l1 inhibitors
|
|
WO2025213154A1
(en)
|
2024-04-05 |
2025-10-09 |
Amgen Inc. |
Gastrointestinal cancer treatments using mta-cooperative prmt5 inhibitors
|
|
WO2025219330A1
(en)
|
2024-04-15 |
2025-10-23 |
Institut National de la Santé et de la Recherche Médicale |
Detection of ppix for use in methods for melanoma ferroptosis sensitivity and targeted therapy resistance prediction
|
|
WO2025228998A1
(en)
|
2024-04-30 |
2025-11-06 |
Institut National de la Santé et de la Recherche Médicale |
Use of hdac4 inhibitors for the treatment of melanoma
|
|
WO2025232879A1
(en)
|
2024-05-10 |
2025-11-13 |
Cytocares (Shanghai) Inc. |
Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025247829A1
(en)
|
2024-05-27 |
2025-12-04 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating prostate cancer
|
|
NL2037811B1
(en)
|
2024-05-29 |
2025-12-12 |
Univ Oslo |
Treatment for Cancer
|
|
GB202408360D0
(en)
|
2024-06-11 |
2024-07-24 |
Cancer Research Tech Ltd |
Tumour sensitisation
|