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MXPA06002880A - Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes. - Google Patents

Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes.

Info

Publication number
MXPA06002880A
MXPA06002880A MXPA06002880A MXPA06002880A MXPA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A
Authority
MX
Mexico
Prior art keywords
compounds
formulas
pyrrolo
trifluoro
phenyl
Prior art date
Application number
MXPA06002880A
Other languages
English (en)
Inventor
Ji Wang
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MXPA06002880A publication Critical patent/MXPA06002880A/es

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    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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Abstract

Compuestos de la Formulas (IA), (IB), (IC), y (ID) (ver formulas (IA), (IB), (IC), y (ID)) en las cuales R1, R2, R3, R4, R5 y R6 son como se definen respectivamente en la presente para las Formulas (IA), (IB), (IC), y (ID), o un tautomero, profarmaco, solvato o una sal de los mismos, composiciones farmaceuticas que contienen tales compuestos, y metodos para modular la funcion del receptor de glucocorticoides y metodos para tratar un estado o un cuadro patologico mediado por la funcion del receptor de glucocorticoides o caracterizado por procesos inflamatorios, alergicos o proliferativos en un paciente que utiliza estos compuestos.
MXPA06002880A 2003-09-24 2004-09-22 Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes. MXPA06002880A (es)

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US50545603P 2003-09-24 2003-09-24
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