AR054347A1 - Combinaciones terapeuticas para el tratamiento o la prevencion de la depresion - Google Patents
Combinaciones terapeuticas para el tratamiento o la prevencion de la depresionInfo
- Publication number
- AR054347A1 AR054347A1 ARP060101594A ARP060101594A AR054347A1 AR 054347 A1 AR054347 A1 AR 054347A1 AR P060101594 A ARP060101594 A AR P060101594A AR P060101594 A ARP060101594 A AR P060101594A AR 054347 A1 AR054347 A1 AR 054347A1
- Authority
- AR
- Argentina
- Prior art keywords
- depression
- treatment
- prevention
- therapeutic combinations
- combinations
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proporcionan combinaciones terapéuticas utiles en el tratamiento o prevencion de la depresion u otros trastornos del temperamento, composiciones farmacéuticas que contienen dichas combinaciones, y su uso en el tratamiento o profilaxis de la depresion u otros trastornos del temperamento. Tales compuestos son de formula (1), o una sal farmacéuticamente aceptable de los mismos, donde cada uno de R1, R2, R3, n, y, y Ar son como de definio y describio en la presente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67404805P | 2005-04-22 | 2005-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054347A1 true AR054347A1 (es) | 2007-06-20 |
Family
ID=36809594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060101594A AR054347A1 (es) | 2005-04-22 | 2006-04-21 | Combinaciones terapeuticas para el tratamiento o la prevencion de la depresion |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7396857B2 (es) |
| EP (1) | EP1871355A1 (es) |
| JP (1) | JP2008536946A (es) |
| CN (1) | CN101198322A (es) |
| AR (1) | AR054347A1 (es) |
| AU (1) | AU2006239918A1 (es) |
| BR (1) | BRPI0610044A2 (es) |
| CA (1) | CA2604915A1 (es) |
| GT (1) | GT200600163A (es) |
| MX (1) | MX2007012882A (es) |
| PE (1) | PE20061327A1 (es) |
| TW (1) | TW200722081A (es) |
| WO (1) | WO2006116149A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
| GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
| RU2007139543A (ru) * | 2005-04-22 | 2009-05-27 | Вайет (Us) | Производные бензодиоксана и бензодиоксолана и их применение |
| MX2007013023A (es) * | 2005-04-22 | 2007-12-13 | Wyeth Corp | Tratamiento del dolor. |
| GT200600166A (es) * | 2005-04-22 | 2007-03-14 | Derivados de cromano y cromeno y usos de los mismos | |
| MX2007012936A (es) * | 2005-04-22 | 2008-01-11 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
| CA2605435A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
| AR056321A1 (es) * | 2005-04-22 | 2007-10-03 | Wyeth Corp | COMBINACIONES TERAPÉUTICAS PARA EL TRATAMIENTO O LA PREVENCIoN DE TRASTORNOS PSICoTICOS |
| EP1871755A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
| AU2006239922A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-HT2c agonists |
| EP1874292A2 (en) * | 2005-04-24 | 2008-01-09 | Wyeth | Methods for modulating bladder function |
| MX2008012212A (es) * | 2006-03-24 | 2008-10-02 | Wyeth Corp | Metodos para tratar trastornos cognitivos y otros afines. |
| AU2008248382B2 (en) * | 2007-05-07 | 2013-07-18 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders |
| US8198268B2 (en) | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| WO2011011594A2 (en) * | 2009-07-23 | 2011-01-27 | Shriners Hospitals For Children | Intracellular toll-like receptors pathways and axonal degeneration |
| EP2510949A4 (en) | 2009-12-11 | 2013-11-13 | Astellas Pharma Inc | THERAPEUTICS FOR FIBROMYALGIA |
| CN102250048B (zh) * | 2011-06-03 | 2013-06-05 | 浙江工业大学 | 2-苯硒基甲基-2,3-二氢苯并呋喃及其制备与应用 |
| JP6709887B2 (ja) * | 2014-09-26 | 2020-06-17 | ヒューマン・メタボローム・テクノロジーズ株式会社 | うつ病治療薬の選択肢を予測する方法 |
| EP3870292A4 (en) | 2018-10-26 | 2022-11-09 | The Research Foundation for The State University of New York | COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA |
| WO2020168337A1 (en) | 2019-02-17 | 2020-08-20 | Magid Abraham | Compositions and methods for treatment of depression and other disorders |
| CN120040398A (zh) | 2020-06-08 | 2025-05-27 | 泰科根公司 | 用于精神障碍或精神增强的有利苯并呋喃组合物 |
| CA3187217A1 (en) | 2020-08-06 | 2022-02-10 | Matthew BAGGOTT | 2-aminoindane compounds for mental disorders or enhancement |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3513239A (en) * | 1967-03-15 | 1970-05-19 | Smithkline Corp | Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith |
| US3826835A (en) * | 1971-01-08 | 1974-07-30 | Ciba Geigy Corp | 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics |
| JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
| JPH06316563A (ja) | 1993-05-06 | 1994-11-15 | Yoshitomi Pharmaceut Ind Ltd | アミド化合物 |
| ES2273764T3 (es) * | 1993-06-28 | 2007-05-16 | Wyeth | Nuevos tratamientos que utilizan derivados de fenetilamina. |
| US6150402A (en) * | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
| AU1106195A (en) | 1994-11-09 | 1996-06-06 | Novo Nordisk A/S | Heterocyclic compounds, their preparation and use |
| US5756532A (en) * | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
| US6274171B1 (en) * | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| DE19909760B4 (de) | 1998-04-17 | 2015-05-21 | Merck Patent Gmbh | Benzofuran-Derivate |
| US7045545B1 (en) * | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
| SE9902267D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
| US20020107244A1 (en) * | 2001-02-02 | 2002-08-08 | Howard Harry R. | Combination treatment for depression |
| US6969730B2 (en) * | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
| KR100446235B1 (ko) * | 2001-05-07 | 2004-08-30 | 엘지전자 주식회사 | 다중 후보를 이용한 움직임 벡터 병합 탐색 방법 |
| WO2003029239A1 (en) * | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
| CN1561338A (zh) * | 2001-10-04 | 2005-01-05 | 惠氏公司 | 作为5-羟基色胺-6配体的苯并二氢吡喃衍生物 |
| US6667322B2 (en) * | 2001-10-05 | 2003-12-23 | Wyeth | Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole |
| US20030134835A1 (en) * | 2002-01-11 | 2003-07-17 | Arthur Hancock | Histamine-3 receptor ligands for diabetes conditions |
| US7208502B2 (en) * | 2002-01-18 | 2007-04-24 | Maniv Energy Capital | Methods of treating conditions associated with an Edg-3 receptor |
| US20030092770A1 (en) * | 2002-10-23 | 2003-05-15 | Phil Skolnick | Combination therapy for treatment of depression |
| EP1611902A4 (en) | 2003-04-03 | 2006-04-12 | Kyowa Hakko Kogyo Kk | MEANS FOR THE PREVENTION AND / OR TREATMENT OF NEUROPATHIC PAIN |
| US7872014B2 (en) * | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US7728155B2 (en) * | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
| US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| CA2553084A1 (en) | 2004-01-28 | 2005-08-11 | Kissei Pharmaceutical Co., Ltd. | Novel benzofuran derivative, medicinal composition containing the same, and uses of these |
| DE102004030099A1 (de) | 2004-06-22 | 2006-01-12 | Grünenthal GmbH | Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren |
| WO2006000902A1 (en) | 2004-06-25 | 2006-01-05 | Pfizer Products Inc. | Dihydrobenzofuran compounds and uses thereof |
| GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
| GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
| EP1879875A1 (en) * | 2005-04-22 | 2008-01-23 | Wyeth | Crystal forms opf {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride |
| CA2605435A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
| AU2006239922A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-HT2c agonists |
| CN101389325A (zh) * | 2005-04-22 | 2009-03-18 | 惠氏公司 | 药物滥用的治疗 |
| GT200600166A (es) * | 2005-04-22 | 2007-03-14 | Derivados de cromano y cromeno y usos de los mismos | |
| AR056321A1 (es) * | 2005-04-22 | 2007-10-03 | Wyeth Corp | COMBINACIONES TERAPÉUTICAS PARA EL TRATAMIENTO O LA PREVENCIoN DE TRASTORNOS PSICoTICOS |
| MX2007012936A (es) * | 2005-04-22 | 2008-01-11 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
| EP1871755A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
| MX2007013023A (es) * | 2005-04-22 | 2007-12-13 | Wyeth Corp | Tratamiento del dolor. |
| EP1874292A2 (en) * | 2005-04-24 | 2008-01-09 | Wyeth | Methods for modulating bladder function |
| MX2008012212A (es) * | 2006-03-24 | 2008-10-02 | Wyeth Corp | Metodos para tratar trastornos cognitivos y otros afines. |
-
2006
- 2006-04-21 EP EP06769874A patent/EP1871355A1/en not_active Withdrawn
- 2006-04-21 BR BRPI0610044-9A patent/BRPI0610044A2/pt not_active Application Discontinuation
- 2006-04-21 WO PCT/US2006/015191 patent/WO2006116149A1/en not_active Ceased
- 2006-04-21 CA CA002604915A patent/CA2604915A1/en not_active Abandoned
- 2006-04-21 PE PE2006000418A patent/PE20061327A1/es not_active Application Discontinuation
- 2006-04-21 AU AU2006239918A patent/AU2006239918A1/en not_active Abandoned
- 2006-04-21 TW TW095114318A patent/TW200722081A/zh unknown
- 2006-04-21 AR ARP060101594A patent/AR054347A1/es not_active Application Discontinuation
- 2006-04-21 CN CNA2006800218927A patent/CN101198322A/zh active Pending
- 2006-04-21 GT GT200600163A patent/GT200600163A/es unknown
- 2006-04-21 US US11/409,480 patent/US7396857B2/en not_active Expired - Fee Related
- 2006-04-21 MX MX2007012882A patent/MX2007012882A/es not_active Application Discontinuation
- 2006-04-21 JP JP2008507943A patent/JP2008536946A/ja active Pending
-
2008
- 2008-05-30 US US12/130,665 patent/US20080269321A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006239918A1 (en) | 2006-11-02 |
| PE20061327A1 (es) | 2007-01-02 |
| US20080269321A1 (en) | 2008-10-30 |
| US20060258715A1 (en) | 2006-11-16 |
| CN101198322A (zh) | 2008-06-11 |
| EP1871355A1 (en) | 2008-01-02 |
| CA2604915A1 (en) | 2006-11-02 |
| GT200600163A (es) | 2007-03-14 |
| BRPI0610044A2 (pt) | 2010-05-25 |
| TW200722081A (en) | 2007-06-16 |
| MX2007012882A (es) | 2007-12-10 |
| US7396857B2 (en) | 2008-07-08 |
| JP2008536946A (ja) | 2008-09-11 |
| WO2006116149A1 (en) | 2006-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |