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WO2002036609A3 - Haplotypes of the chrm4 gene - Google Patents

Haplotypes of the chrm4 gene Download PDF

Info

Publication number
WO2002036609A3
WO2002036609A3 PCT/US2001/045709 US0145709W WO0236609A3 WO 2002036609 A3 WO2002036609 A3 WO 2002036609A3 US 0145709 W US0145709 W US 0145709W WO 0236609 A3 WO0236609 A3 WO 0236609A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
chrm4
gene
disclosed
chrm4 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/045709
Other languages
French (fr)
Other versions
WO2002036609A2 (en
Inventor
R Rex Denton
Amy Duda
Christopher Raleigh Gilson
Amir Kazemi
Krishnan Nandabalan
Charles Tirrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2002228727A priority Critical patent/AU2002228727A1/en
Publication of WO2002036609A2 publication Critical patent/WO2002036609A2/en
Publication of WO2002036609A3 publication Critical patent/WO2002036609A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel genetic variants of the Cholinergic Receptor, Muscarinic 4 (CHRM4) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the CHRM4 gene. Compositions and methods for haplotyping and/or genotyping the CHRM4 gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/045709 2000-10-31 2001-10-31 Haplotypes of the chrm4 gene Ceased WO2002036609A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002228727A AU2002228727A1 (en) 2000-10-31 2001-10-31 Haplotypes of the chrm4 gene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24462700P 2000-10-31 2000-10-31

Publications (2)

Publication Number Publication Date
WO2002036609A2 WO2002036609A2 (en) 2002-05-10
WO2002036609A3 true WO2002036609A3 (en) 2002-09-06

Family

ID=22923502

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045709 Ceased WO2002036609A2 (en) 2000-10-31 2001-10-31 Haplotypes of the chrm4 gene

Country Status (2)

Country Link
AU (1) AU2002228727A1 (en)
WO (1) WO2002036609A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004071392A2 (en) * 2003-02-11 2004-08-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with acetylcholine receptor, muscarinic 4(m4)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] October 1994 (1994-10-01), BONNER ET AL.: "Human m4 muscarinic acetylcholine receptor gene", XP002950833, Database accession no. (M16405) *
DATABASE SNP [online] NATIONAL LIBRARY OF MEDICINE, NIH (BETHESDA, MD, USA); April 2001 (2001-04-01), XP002950629, retrieved from SS72979107 accession no. NCBI Database accession no. (RS2067482) *
DATABASE SNP [online] NATIONAL LIBRARY OF MEDICINE, NIH (BETHESDA, MD, USA); June 2001 (2001-06-01), XP002950630, retrieved from SS3176155 accession no. NCBI Database accession no. (RS2229163) *
KOPPEN ET AL.: "Isolation, sequence and functional expression of the mouse m4 muscarinic acetylcholine receptor gene", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1173, 1993, pages 342 - 344, XP002950828 *
SCIENCE, vol. 237, no. 4814, 1987, pages 527 - 532 *

Also Published As

Publication number Publication date
WO2002036609A2 (en) 2002-05-10
AU2002228727A1 (en) 2002-05-15

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