RU2009105196A - Противовирусные соединения (варианты), фармацевтическая композиция на их основе, названные соединения для изготовления лекарственного средства, способ лечения или профилактики вирусной инфекции с их помощью - Google Patents
Противовирусные соединения (варианты), фармацевтическая композиция на их основе, названные соединения для изготовления лекарственного средства, способ лечения или профилактики вирусной инфекции с их помощью Download PDFInfo
- Publication number
- RU2009105196A RU2009105196A RU2009105196/04A RU2009105196A RU2009105196A RU 2009105196 A RU2009105196 A RU 2009105196A RU 2009105196/04 A RU2009105196/04 A RU 2009105196/04A RU 2009105196 A RU2009105196 A RU 2009105196A RU 2009105196 A RU2009105196 A RU 2009105196A
- Authority
- RU
- Russia
- Prior art keywords
- substituted
- carbonylmethyl
- methyl
- amino
- group
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 53
- 230000000840 anti-viral effect Effects 0.000 title claims abstract 7
- 238000000034 method Methods 0.000 title claims 5
- 208000036142 Viral infection Diseases 0.000 title claims 4
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- -1 amino, substituted amino Chemical group 0.000 claims abstract 280
- 125000000623 heterocyclic group Chemical group 0.000 claims abstract 35
- 125000001072 heteroaryl group Chemical group 0.000 claims abstract 31
- 125000000217 alkyl group Chemical group 0.000 claims abstract 27
- 125000000547 substituted alkyl group Chemical group 0.000 claims abstract 20
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract 19
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 15
- 239000001257 hydrogen Substances 0.000 claims abstract 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 15
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract 14
- 125000004433 nitrogen atom Chemical group N* 0.000 claims abstract 14
- 125000003118 aryl group Chemical group 0.000 claims abstract 12
- 125000005842 heteroatom Chemical group 0.000 claims abstract 10
- 125000003107 substituted aryl group Chemical group 0.000 claims abstract 10
- 229910052736 halogen Inorganic materials 0.000 claims abstract 9
- 150000002367 halogens Chemical group 0.000 claims abstract 9
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 8
- 125000005415 substituted alkoxy group Chemical group 0.000 claims abstract 8
- 229910052717 sulfur Inorganic materials 0.000 claims abstract 8
- 125000004429 atom Chemical group 0.000 claims abstract 7
- 125000000753 cycloalkyl group Chemical group 0.000 claims abstract 7
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract 6
- 229910052760 oxygen Inorganic materials 0.000 claims abstract 6
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims abstract 6
- 125000000392 cycloalkenyl group Chemical group 0.000 claims abstract 5
- 125000002619 bicyclic group Chemical group 0.000 claims abstract 4
- 150000001204 N-oxides Chemical class 0.000 claims abstract 2
- 125000000732 arylene group Chemical group 0.000 claims abstract 2
- 125000005549 heteroarylene group Chemical group 0.000 claims abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 14
- 241000711549 Hepacivirus C Species 0.000 claims 11
- 125000003342 alkenyl group Chemical group 0.000 claims 7
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 7
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 6
- 125000000719 pyrrolidinyl group Chemical group 0.000 claims 6
- 125000000304 alkynyl group Chemical group 0.000 claims 5
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 5
- 125000003386 piperidinyl group Chemical group 0.000 claims 5
- 125000005017 substituted alkenyl group Chemical group 0.000 claims 5
- 125000004426 substituted alkynyl group Chemical group 0.000 claims 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000002252 acyl group Chemical group 0.000 claims 4
- 125000004442 acylamino group Chemical group 0.000 claims 4
- 125000000266 alpha-aminoacyl group Chemical group 0.000 claims 4
- 125000004093 cyano group Chemical group *C#N 0.000 claims 4
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 4
- 125000004194 piperazin-1-yl group Chemical group [H]N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 125000001424 substituent group Chemical group 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 125000005518 carboxamido group Chemical group 0.000 claims 3
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 3
- 125000001188 haloalkyl group Chemical group 0.000 claims 3
- 230000001404 mediated effect Effects 0.000 claims 3
- 230000009385 viral infection Effects 0.000 claims 3
- 125000004502 1,2,3-oxadiazolyl group Chemical group 0.000 claims 2
- 125000001399 1,2,3-triazolyl group Chemical group N1N=NC(=C1)* 0.000 claims 2
- 125000004520 1,3,4-thiadiazolyl group Chemical group 0.000 claims 2
- 125000003363 1,3,5-triazinyl group Chemical group N1=C(N=CN=C1)* 0.000 claims 2
- 125000004463 2,4-dimethyl-thiazol-5-yl group Chemical group CC=1SC(=C(N1)C)* 0.000 claims 2
- FPZWZCWUIYYYBU-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl acetate Chemical group CCOCCOCCOC(C)=O FPZWZCWUIYYYBU-UHFFFAOYSA-N 0.000 claims 2
- 125000004575 3-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 241000710781 Flaviviridae Species 0.000 claims 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 125000004103 aminoalkyl group Chemical group 0.000 claims 2
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 125000004618 benzofuryl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 claims 2
- 125000001164 benzothiazolyl group Chemical group S1C(=NC2=C1C=CC=C2)* 0.000 claims 2
- 125000004196 benzothienyl group Chemical group S1C(=CC2=C1C=CC=C2)* 0.000 claims 2
- AGSPXMVUFBBBMO-UHFFFAOYSA-N beta-aminopropionitrile Chemical compound NCCC#N AGSPXMVUFBBBMO-UHFFFAOYSA-N 0.000 claims 2
- 235000010290 biphenyl Nutrition 0.000 claims 2
- 239000004305 biphenyl Substances 0.000 claims 2
- 150000001735 carboxylic acids Chemical class 0.000 claims 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 claims 2
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000002541 furyl group Chemical group 0.000 claims 2
- 125000004446 heteroarylalkyl group Chemical group 0.000 claims 2
- 125000004415 heterocyclylalkyl group Chemical group 0.000 claims 2
- 125000002883 imidazolyl group Chemical group 0.000 claims 2
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 claims 2
- 125000001041 indolyl group Chemical group 0.000 claims 2
- 125000000904 isoindolyl group Chemical group C=1(NC=C2C=CC=CC12)* 0.000 claims 2
- 125000002183 isoquinolinyl group Chemical group C1(=NC=CC2=CC=CC=C12)* 0.000 claims 2
- 125000001786 isothiazolyl group Chemical group 0.000 claims 2
- 125000000842 isoxazolyl group Chemical group 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 claims 2
- 125000002971 oxazolyl group Chemical group 0.000 claims 2
- 125000004482 piperidin-4-yl group Chemical group N1CCC(CC1)* 0.000 claims 2
- 125000001042 pteridinyl group Chemical group N1=C(N=CC2=NC=CN=C12)* 0.000 claims 2
- 125000000561 purinyl group Chemical group N1=C(N=C2N=CNC2=C1)* 0.000 claims 2
- 125000003373 pyrazinyl group Chemical group 0.000 claims 2
- 125000003226 pyrazolyl group Chemical group 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 125000000714 pyrimidinyl group Chemical group 0.000 claims 2
- 125000000168 pyrrolyl group Chemical group 0.000 claims 2
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 claims 2
- 125000005493 quinolyl group Chemical group 0.000 claims 2
- 125000004299 tetrazol-5-yl group Chemical group [H]N1N=NC(*)=N1 0.000 claims 2
- 125000000335 thiazolyl group Chemical group 0.000 claims 2
- 125000001544 thienyl group Chemical group 0.000 claims 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 2
- 125000001140 1,4-phenylene group Chemical group [H]C1=C([H])C([*:2])=C([H])C([H])=C1[*:1] 0.000 claims 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 125000004195 4-methylpiperazin-1-yl group Chemical group [H]C([H])([H])N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 claims 1
- 208000005176 Hepatitis C Diseases 0.000 claims 1
- 102000016600 Inosine-5'-monophosphate dehydrogenases Human genes 0.000 claims 1
- 108050006182 Inosine-5'-monophosphate dehydrogenases Proteins 0.000 claims 1
- 108060004795 Methyltransferase Proteins 0.000 claims 1
- 101800001019 Non-structural protein 4B Proteins 0.000 claims 1
- 101800001014 Non-structural protein 5A Proteins 0.000 claims 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 1
- 125000001116 prolino group Chemical group [H]OC(=O)C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000011282 treatment Methods 0.000 claims 1
- VTYODXDRJFOWMT-OUCADQQQSA-N CCC[C@@]1([C@H](C)C(C)(C)C[C@H](C)C1)NC Chemical compound CCC[C@@]1([C@H](C)C(C)(C)C[C@H](C)C1)NC VTYODXDRJFOWMT-OUCADQQQSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83104006P | 2006-07-14 | 2006-07-14 | |
| US60/831,040 | 2006-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2009105196A true RU2009105196A (ru) | 2010-08-27 |
Family
ID=38742551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009105196/04A RU2009105196A (ru) | 2006-07-14 | 2007-07-12 | Противовирусные соединения (варианты), фармацевтическая композиция на их основе, названные соединения для изготовления лекарственного средства, способ лечения или профилактики вирусной инфекции с их помощью |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP2044083A1 (zh) |
| JP (1) | JP2009543807A (zh) |
| KR (1) | KR20090033881A (zh) |
| CN (1) | CN101490058A (zh) |
| AR (1) | AR062258A1 (zh) |
| AU (1) | AU2007272441A1 (zh) |
| BR (1) | BRPI0714346A2 (zh) |
| CA (1) | CA2657651A1 (zh) |
| MX (1) | MX2009000513A (zh) |
| PE (1) | PE20080427A1 (zh) |
| RU (1) | RU2009105196A (zh) |
| TW (1) | TW200813070A (zh) |
| WO (2) | WO2008008907A2 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9108983B2 (en) | 2013-07-23 | 2015-08-18 | Les Laboratoires Servier | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
| US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
| CN102872461A (zh) | 2007-05-04 | 2013-01-16 | 弗特克斯药品有限公司 | 用于治疗hcv感染的组合治疗 |
| US8362068B2 (en) | 2009-12-18 | 2013-01-29 | Idenix Pharmaceuticals, Inc. | 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors |
| EP2655362A1 (en) * | 2010-12-22 | 2013-10-30 | Abbvie Inc. | Hepatitis c inhibitors and uses thereof |
| US20120252721A1 (en) * | 2011-03-31 | 2012-10-04 | Idenix Pharmaceuticals, Inc. | Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor |
| RU2546006C1 (ru) | 2014-03-07 | 2015-04-10 | Римма Ильинична Ашкинази | Противовирусное средство |
| WO2016118043A1 (ru) | 2015-01-20 | 2016-07-28 | Виктор Вениаминович ТЕЦ | Гемостатическое средство |
| US10167293B2 (en) * | 2016-05-26 | 2019-01-01 | Bayer Pharma Aktiengesellschaft | [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones |
| AU2018272839B2 (en) | 2017-05-24 | 2024-12-05 | Georgy Viktorovich Tets | Fractionated antimicrobial compositions and use thereof |
| TWI861488B (zh) * | 2021-04-16 | 2024-11-11 | 美商基利科學股份有限公司 | 噻吩并吡咯化合物 |
| KR20240056747A (ko) | 2021-09-10 | 2024-04-30 | 길리애드 사이언시즈, 인코포레이티드 | 티에노피롤 화합물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0210357A (pt) * | 2001-06-11 | 2004-06-29 | Shire Biochem Inc | Composto e métodos para o tratamento ou a prevenção de infecções pelo flavivìrus |
| KR20060015742A (ko) * | 2003-06-04 | 2006-02-20 | 제네랩스 테크놀로지스, 인코포레이티드 | Ｈｃｖ 감염의 치료를 위한 질소 함유 헤테로아릴 유도체 |
-
2007
- 2007-07-12 RU RU2009105196/04A patent/RU2009105196A/ru not_active Application Discontinuation
- 2007-07-12 WO PCT/US2007/073386 patent/WO2008008907A2/en not_active Ceased
- 2007-07-12 EP EP07799544A patent/EP2044083A1/en not_active Withdrawn
- 2007-07-12 CA CA002657651A patent/CA2657651A1/en not_active Abandoned
- 2007-07-12 MX MX2009000513A patent/MX2009000513A/es not_active Application Discontinuation
- 2007-07-12 BR BRPI0714346-0A patent/BRPI0714346A2/pt not_active Application Discontinuation
- 2007-07-12 JP JP2009519699A patent/JP2009543807A/ja active Pending
- 2007-07-12 KR KR1020097001707A patent/KR20090033881A/ko not_active Withdrawn
- 2007-07-12 WO PCT/US2007/073391 patent/WO2008008912A1/en not_active Ceased
- 2007-07-12 AU AU2007272441A patent/AU2007272441A1/en not_active Abandoned
- 2007-07-12 CN CNA2007800266569A patent/CN101490058A/zh active Pending
- 2007-07-13 TW TW096125693A patent/TW200813070A/zh unknown
- 2007-07-13 AR ARP070103144A patent/AR062258A1/es unknown
- 2007-07-13 PE PE2007000902A patent/PE20080427A1/es not_active Application Discontinuation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9108983B2 (en) | 2013-07-23 | 2015-08-18 | Les Laboratoires Servier | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them |
| EA026906B1 (ru) * | 2013-07-23 | 2017-05-31 | Ле Лаборатуар Сервье | Новые пиррольные соединения, способ их получения и фармацевтические композиции, содержащие их |
| US10688101B2 (en) | 2013-07-23 | 2020-06-23 | Les Laboratories Servier | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them |
| US11058689B2 (en) | 2013-07-23 | 2021-07-13 | Les Laboratoires Servier | Pyrrole compounds, a process for their preparation and pharmaceutical |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090033881A (ko) | 2009-04-06 |
| CN101490058A (zh) | 2009-07-22 |
| WO2008008907A2 (en) | 2008-01-17 |
| AU2007272441A1 (en) | 2008-01-17 |
| BRPI0714346A2 (pt) | 2013-03-19 |
| WO2008008907A3 (en) | 2008-03-20 |
| CA2657651A1 (en) | 2008-01-17 |
| TW200813070A (en) | 2008-03-16 |
| WO2008008912A1 (en) | 2008-01-17 |
| MX2009000513A (es) | 2009-03-09 |
| AR062258A1 (es) | 2008-10-29 |
| AU2007272441A2 (en) | 2009-03-19 |
| EP2044083A1 (en) | 2009-04-08 |
| PE20080427A1 (es) | 2008-06-11 |
| JP2009543807A (ja) | 2009-12-10 |
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