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PT3927337T - 5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major - Google Patents

5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major

Info

Publication number
PT3927337T
PT3927337T PT207100595T PT20710059T PT3927337T PT 3927337 T PT3927337 T PT 3927337T PT 207100595 T PT207100595 T PT 207100595T PT 20710059 T PT20710059 T PT 20710059T PT 3927337 T PT3927337 T PT 3927337T
Authority
PT
Portugal
Prior art keywords
dimethyltryptamine
dmt
meo
methoxy
treating depression
Prior art date
Application number
PT207100595T
Other languages
English (en)
Original Assignee
Gh Res Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=65529503&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3927337(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gh Res Ireland Limited filed Critical Gh Res Ireland Limited
Publication of PT3927337T publication Critical patent/PT3927337T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PT207100595T 2019-02-22 2020-02-24 5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major PT3927337T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19158774 2019-02-22

Publications (1)

Publication Number Publication Date
PT3927337T true PT3927337T (pt) 2024-05-17

Family

ID=65529503

Family Applications (2)

Application Number Title Priority Date Filing Date
PT241574250T PT4349407T (pt) 2019-02-22 2020-02-24 5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major
PT207100595T PT3927337T (pt) 2019-02-22 2020-02-24 5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT241574250T PT4349407T (pt) 2019-02-22 2020-02-24 5-metoxi-n,n-dimetiltriptamina (5-meo-dmt) para o tratamento da depressão major

Country Status (32)

Country Link
US (2) US20220071958A1 (pt)
EP (3) EP4349407B1 (pt)
JP (2) JP7598326B2 (pt)
KR (1) KR20210154966A (pt)
CN (1) CN114555078A (pt)
AU (1) AU2020225410B2 (pt)
BR (1) BR112021016153A2 (pt)
CA (1) CA3130406A1 (pt)
CL (1) CL2021002174A1 (pt)
CO (1) CO2021010882A2 (pt)
CR (1) CR20210437A (pt)
DK (2) DK3927337T3 (pt)
DO (1) DOP2021000176A (pt)
EA (1) EA202192318A1 (pt)
EC (1) ECSP21060868A (pt)
ES (2) ES3031965T3 (pt)
FI (2) FI4349407T3 (pt)
HR (2) HRP20250590T1 (pt)
HU (2) HUE071841T2 (pt)
IL (1) IL285537A (pt)
LT (2) LT4349407T (pt)
MA (1) MA55021B1 (pt)
MD (1) MD3927337T2 (pt)
MX (2) MX2021009941A (pt)
NI (1) NI202100080A (pt)
PE (1) PE20220015A1 (pt)
PL (2) PL4349407T3 (pt)
PT (2) PT4349407T (pt)
RS (2) RS65706B1 (pt)
SI (2) SI4349407T1 (pt)
SM (1) SMT202400154T1 (pt)
WO (1) WO2020169850A1 (pt)

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GB201907871D0 (en) 2019-06-03 2019-07-17 Small Pharma Ltd Therapeutic compositions
EP3753923A1 (en) * 2019-06-19 2020-12-23 GH Research Limited Recrystallisation of 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) in methyl tert.-butyl ether (mtbe) without adding an anti-solvent
PT3873883T (pt) 2019-11-07 2023-03-24 Small Pharma Ltd Método de síntese
EP3868364A1 (en) * 2020-02-24 2021-08-25 GH Research Limited Aerosol comprising 5-methoxy-n,n-dimethyltryptamine
IL297861A (en) 2020-05-08 2023-01-01 Psilera Inc Novel compositions of matter and pharmaceutical compositions
PH12022553135A1 (en) 2020-05-19 2024-03-04 Cybin Irl Ltd Deuterated tryptamine derivatives and methods of use
US12042564B2 (en) 2020-06-02 2024-07-23 Cybin Uk Ltd Therapeutic solid dosage forms
US11773062B2 (en) 2021-03-22 2023-10-03 Small Pharma Ltd Deuterated compounds
EP4595962A3 (en) 2020-06-12 2025-10-22 Beckley Psytech Limited Pharmaceutical composition
JP7567024B2 (ja) * 2020-08-05 2024-10-15 ユニヴェルシテートスピタル バーゼル Ｄｍｔ補助心理療法のための静脈内ｄｍｔ投与方法
EP4200021A1 (en) 2020-08-18 2023-06-28 Cybin IRL Limited Therapeutic phenethylamine compositions and methods of use
AU2021334933B2 (en) * 2020-08-28 2023-01-19 Cybin Uk Ltd Injectable formulation
US11406619B2 (en) 2020-08-28 2022-08-09 Small Pharma Ltd Injectable formulations
CA3194558A1 (en) * 2020-10-02 2022-04-07 Brett J. GREENE Methods for delivery of psychedelic medications by inhalation and systems for performing the methods
CN112138028A (zh) * 2020-10-10 2020-12-29 南京中医药大学 蟾蜍色胺类物质在制备抗抑郁药物中的应用
WO2022082058A1 (en) * 2020-10-16 2022-04-21 Eleusis Therapeutics Us, Inc. Method of treatment by tryptamine alkaloids
WO2022117640A1 (en) * 2020-12-01 2022-06-09 Small Pharma Ltd Inhalable formulations
US11660289B2 (en) 2020-12-01 2023-05-30 Small Pharma Ltd. Deuterated or partially deuterated N,N-dimethyltryptamine compounds
US20220265582A1 (en) * 2021-02-24 2022-08-25 Universitätsspital Basel Effects of mescaline and of mescaline analogs (scalines) to assist psychotherapy
CA3113414A1 (en) * 2021-03-29 2022-09-29 Mind Cure Health Inc. Psychedelics protocol computer systems and methods
BR112023022195A2 (pt) 2021-04-26 2024-01-16 Atai Therapeutics Inc Novas composições e métodos de n,n-dimetiltriptamina
US20230136824A1 (en) 2021-04-26 2023-05-04 ATAI Life Sciences AG N-n-dimethyltryptamine (dmt) and dmt analog compositions, methods of making, and methods of use thereof
JP2024517194A (ja) * 2021-05-03 2024-04-19 マインド メディシン， インコーポレイテッド サイケデリック薬の用量を漸増する方法
WO2022235927A1 (en) * 2021-05-05 2022-11-10 Gilgamesh Pharmaceuticals, Inc. Novel tryptamines and methods of treating mood disorders
MX2023013928A (es) 2021-05-25 2023-12-08 Atai Therapeutics Inc Nuevas sales y formas cristalinas de sales de n,n-dimetiltriptamina.
JP2024522174A (ja) 2021-06-09 2024-06-11 アタイ セラピューティクス， インコーポレイテッド ジメチルトリプタミンの新規プロドラッグおよびコンジュゲート
US11697638B2 (en) 2021-09-08 2023-07-11 Small Pharma Ltd 5-methoxy-N,N-dimethyltryptamine crystalline forms
EP4159201A1 (en) * 2021-09-30 2023-04-05 Biomind Labs Inc Encapsulated microparticles and nanoparticles of dimethyltriptamines
US12318477B2 (en) 2021-11-18 2025-06-03 Cybin Uk Ltd Injectable and inhalable formulations
JP2024540527A (ja) * 2021-11-18 2024-10-31 サイビン ユーケー リミテッド 注射製剤及び吸入製剤
US12012381B2 (en) 2021-12-30 2024-06-18 Atai Therapeutics, Inc. Dimethyltryptamine analogues as nitric oxide delivery drugs
EP4486448A1 (en) 2022-03-04 2025-01-08 Reset Pharmaceuticals, Inc. Co-crystals or salts comprising psilocin
EP4499074A1 (en) 2022-03-27 2025-02-05 GH Research Ireland Limited 5-meo-dtm for the treatment of bipolar disorder
AU2023244452A1 (en) 2022-03-27 2024-11-07 GH Research Ireland Limited Treatment of cognitive dysfunction
RS65585B1 (sr) 2022-03-27 2024-06-28 Gh Res Ireland Limited Kristalna so 5-meo-dmt hidrobromid
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof
WO2024160391A1 (en) 2023-01-30 2024-08-08 GH Research Ireland Limited Treatment of mental disorders
IL322428A (en) 2023-01-30 2025-09-01 Gh Res Ireland Limited 5-Methoxy-n,n-dimethyltryptamine for use in the treatment of mental disorders in nursing mothers
GB202306256D0 (en) * 2023-04-27 2023-06-14 Beckley Psytech Ltd 5-Methoxy-N,N-Dimethyltryptamine Formulations
WO2024251807A1 (en) * 2023-06-08 2024-12-12 Cybin Irl Limited Companion animal treatments
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations
WO2025068714A1 (en) * 2023-09-28 2025-04-03 Beckley Psytech Limited Pharmaceutical compositions comprising 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt)
WO2025087962A1 (en) 2023-10-23 2025-05-01 Reconnect Labs Ag Pharmaceutical formulations comprising 5-meo-dmt and their therapeutic uses
WO2025111597A1 (en) * 2023-11-22 2025-05-30 Gilgamesh Pharmaceuticals, Inc. A treatment for patients with mood disorders using n-ethyl-2-(5-fluoro-1h-indol-3-yl)- n-methylethan-1-amine or a pharmaceutically acceptable salt thereof

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DE19803376C1 (de) 1998-01-29 1999-10-14 Markus Storz Inhalator zur Erzeugung von aroma- und/oder wirkstoffhaltigen Dämpfen aus Pflanzenmaterial und/oder Flüssigkeiten
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
JP2007516404A (ja) 2003-05-21 2007-06-21 アレックザ ファーマシューティカルズ， インコーポレイテッド 光学点火されたかまたは電気点火された内蔵式加熱ユニットおよびそれを使用する薬剤供給ユニット
ES2355983T3 (es) 2006-08-01 2011-04-01 STOBI GMBH & CO. KG Balón de válvula para inhaladores .
CN103816150A (zh) * 2014-03-14 2014-05-28 兰州理工大学 山蚂蝗生物碱单体成分的用途
US20200147038A1 (en) * 2017-04-20 2020-05-14 Eleusis Benefit Corporation, Pbc Assessing and treating psychedelic-responsive subjects
EP3713568A1 (en) * 2017-10-26 2020-09-30 Consejo Superior de Investigaciones Cientificas (CSIC) Combination product for the treatment of neurological and/or psychiatric disorders
US20220071958A1 (en) 2019-02-22 2022-03-10 GH Research Ireland Limited 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) for treating depression

Also Published As

Publication number Publication date
JP7598326B2 (ja) 2024-12-11
KR20210154966A (ko) 2021-12-21
US20220071958A1 (en) 2022-03-10
EP4353314A2 (en) 2024-04-17
SI3927337T1 (sl) 2024-07-31
RS66912B1 (sr) 2025-07-31
US20240307350A1 (en) 2024-09-19
CO2021010882A2 (es) 2022-01-17
PT4349407T (pt) 2025-06-04
DK3927337T3 (da) 2024-04-22
IL285537A (en) 2021-09-30
AU2020225410A1 (en) 2021-08-19
CA3130406A1 (en) 2020-08-27
EP4353314A3 (en) 2024-07-03
JP2022521337A (ja) 2022-04-06
BR112021016153A2 (pt) 2021-10-05
MX2025002567A (es) 2025-04-02
ECSP21060868A (es) 2021-11-30
EP4349407B1 (en) 2025-04-09
EA202192318A1 (ru) 2021-12-21
NI202100080A (es) 2021-12-06
LT4349407T (lt) 2025-07-10
HRP20250590T1 (hr) 2025-07-04
SI4349407T1 (sl) 2025-06-30
HUE071841T2 (hu) 2025-09-28
EP3927337B8 (en) 2024-03-20
PL3927337T3 (pl) 2024-07-29
JP2025029035A (ja) 2025-03-05
CN114555078A (zh) 2022-05-27
FI3927337T3 (fi) 2024-05-08
EP3927337B1 (en) 2024-02-14
SMT202400154T1 (it) 2024-07-09
DK4349407T3 (da) 2025-05-26
RS65706B1 (sr) 2024-08-30
MA55021A (fr) 2021-12-29
MX2021009941A (es) 2021-12-10
DOP2021000176A (es) 2021-11-21
PL4349407T3 (pl) 2025-07-21
AU2020225410B2 (en) 2025-10-30
MD3927337T2 (ro) 2024-08-31
CR20210437A (es) 2021-11-02
EP3927337A1 (en) 2021-12-29
HUE066828T2 (hu) 2024-09-28
HRP20240532T1 (hr) 2024-07-19
ES2984438T3 (es) 2024-10-29
MA55021B1 (fr) 2024-05-31
ES3031965T3 (en) 2025-07-14
LT3927337T (lt) 2024-07-10
EP4349407A2 (en) 2024-04-10
CL2021002174A1 (es) 2022-01-28
EP4349407A3 (en) 2024-07-03
FI4349407T3 (fi) 2025-06-02
WO2020169850A1 (en) 2020-08-27
PE20220015A1 (es) 2022-01-11

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