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PL1689233T3 - Bicykliczne inhibitory MEK - Google Patents

Bicykliczne inhibitory MEK

Info

Publication number
PL1689233T3
PL1689233T3 PL04811728T PL04811728T PL1689233T3 PL 1689233 T3 PL1689233 T3 PL 1689233T3 PL 04811728 T PL04811728 T PL 04811728T PL 04811728 T PL04811728 T PL 04811728T PL 1689233 T3 PL1689233 T3 PL 1689233T3
Authority
PL
Poland
Prior art keywords
compounds
mek
mammals
treatment
disclosed
Prior art date
Application number
PL04811728T
Other languages
English (en)
Inventor
Eli Wallace
Hong Woon Yang
Jim Blake
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of PL1689233T3 publication Critical patent/PL1689233T3/pl

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    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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