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PA8631101A1 - Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos - Google Patents

Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos

Info

Publication number
PA8631101A1
PA8631101A1 PA20058631101A PA8631101A PA8631101A1 PA 8631101 A1 PA8631101 A1 PA 8631101A1 PA 20058631101 A PA20058631101 A PA 20058631101A PA 8631101 A PA8631101 A PA 8631101A PA 8631101 A1 PA8631101 A1 PA 8631101A1
Authority
PA
Panama
Prior art keywords
boro
content
pirrol
substituted
carbonitrile
Prior art date
Application number
PA20058631101A
Other languages
English (en)
Inventor
Arkadiy Zinoviy Rubezhov
Bogdan Kazimierz Wilk
Jean Louise Helom
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8631101A1 publication Critical patent/PA8631101A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UNA PREPARACION CONVENIENTE DE COMPUESTOS CON CONTENIDO DE BORO, COMPUESTOS DE PIRROLCARBONITRILO CON CONTENIDO DE BORO, COMPUESTOS DE PIRROL-2-CARBONITRILO N-SUSTITUIDOS CON CONTENIDO DE BORO Y DERIVADOS DE LOS MISMOS. LA PRESENTE INVENCION PRESENTA ASIMISMO EL USO DE ESTOS COMPUESTOS CON CONTENIDO DE BORO Y DERIVADOS DE LOS MISMOS EN REACCIONES DE ACOPLAMIENTO PARA LA PRODUCCION DE COMPUESTOS DE BIARILO.
PA20058631101A 2004-04-27 2005-04-25 Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos PA8631101A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56563604P 2004-04-27 2004-04-27
US64765605P 2005-01-27 2005-01-27

Publications (1)

Publication Number Publication Date
PA8631101A1 true PA8631101A1 (es) 2006-09-08

Family

ID=34967855

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20058631101A PA8631101A1 (es) 2004-04-27 2005-04-25 Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos

Country Status (7)

Country Link
US (2) US7446211B2 (es)
AR (1) AR049631A1 (es)
PA (1) PA8631101A1 (es)
PE (1) PE20060331A1 (es)
SV (1) SV2005002092A (es)
TW (1) TW200604137A (es)
WO (1) WO2005105817A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105739A2 (en) * 2004-04-27 2005-11-10 Wyeth Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same
TW200604137A (en) 2004-04-27 2006-02-01 Wyeth Corp Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
EP1778710B1 (en) * 2004-08-13 2012-01-18 Wyeth LLC Tanaproget derivatives, metabolites, and uses thereof
GT200600173A (es) 2005-04-28 2006-11-22 Forma purificada de tranaproget
US20060246128A1 (en) 2005-04-28 2006-11-02 Wyeth Micronized tanaproget and compositions containing same
MX2007013465A (es) 2005-04-28 2008-01-21 Wyeth Corp Tanaproget micronizado, composiciones y metodos para preparar las mismas.
CN101166736B (zh) 2005-04-28 2013-02-06 惠氏公司 他那普戈特的多晶型ⅱ
PE20070220A1 (es) 2005-07-29 2007-03-19 Wyeth Corp Proceso para la sintesis de moduladores del receptor de progesterona
US20070213526A1 (en) * 2006-03-07 2007-09-13 Wyeth Purification of progesterone receptor modulators
US8207337B2 (en) 2007-01-29 2012-06-26 Wako Pure Chemical Industries, Ltd. Reagent for organic synthesis reaction containing organic triol borate salt
US20080319204A1 (en) * 2007-06-25 2008-12-25 Wyeth Process for the synthesis of progesterone receptor modulators
EA201070715A1 (ru) 2007-12-20 2011-02-28 Тева Вимен'С Хелс, Инк. Режимы дозирования, фармацевтические композиции и упаковки для экстренной контрацепции
EP4146626A4 (en) 2020-05-05 2024-05-29 Nuvalent, Inc. CHEMOTHERAPEUTIC AGENTS BASED ON HETEROAROMATIC MACROCYCLIC ETHERS
PH12022552787A1 (en) 2020-05-05 2024-03-25 Nuvalent Inc Heteroaromatic macrocyclic ether chemotherapeutic agents
CA3231813A1 (en) 2021-10-01 2023-04-06 Sibao CHEN Solid forms, pharmaceutical compositions and preparation of heteroaromatic macrocyclic ether compounds

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US5194628A (en) 1988-03-18 1993-03-16 Ciba-Geigy Corporation Process for the preparation of substituted difluorobenzo-1,3-dioxoles
MX9206628A (es) * 1991-11-22 1993-05-01 Boehringer Ingelheim Pharma Ester de prolinaboronato y metodo para su preparacion.
EP0717740A1 (de) 1993-09-10 1996-06-26 Ciba SC Holding AG Photochrome verbindungen, verfahren und zwischenprodukte zu deren hestellung und deren verwendung
US6545108B1 (en) 1999-02-22 2003-04-08 Eastman Chemical Company Catalysts containing N-pyrrolyl substituted nitrogen donors
US6559091B1 (en) 1999-02-22 2003-05-06 Eastman Chemical Company Catalysts containing N-pyrrolyl substituted nitrogen donors
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US7306643B2 (en) * 2000-01-10 2007-12-11 Sulzer Chemtech Ag Method for introducing additives to liquid metal, ceramic/metallic powder
US20020065192A1 (en) 2000-02-18 2002-05-30 Mackenzie Peter Borden Productivity catalysts and microstructure control
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
US6350837B1 (en) 2000-06-09 2002-02-26 Eastman Chemical Company Copolymerization of norbornene and functional norbornene monomers
EP1351997A2 (en) 2000-11-06 2003-10-15 Eastman Chemical Company Improved productivity catalysts and microstructure control
WO2002036642A2 (en) 2000-11-06 2002-05-10 Eastman Chemical Company Olefin polymerization processes using supported catalysts
US6387992B1 (en) 2000-11-27 2002-05-14 Ciba Specialty Chemicals Corporation Substituted 5-heteroaryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, a process for preparation thereof and compositions stabilized therewith
JP4307071B2 (ja) 2000-11-27 2009-08-05 チバ ホールディング インコーポレーテッド Ｕｖ吸収剤としての置換５−アリール及び５−ヘテロアリール−２−（２−ヒドロキシフェニル）−２ｈ−ベンゾトリアゾール誘導体
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JP2005194190A (ja) 2001-10-05 2005-07-21 Fumie Satou １９−ノル−ビタミンｄ誘導体の製造法
DE10152989A1 (de) 2001-10-26 2003-05-08 Bayer Ag Komplexe N-heterocyslischer Carbene und ihre Verwendung
AU2003223930A1 (en) 2002-06-14 2003-12-31 Novo Nordisk A/S Pharmaceutical use of boronic acids and esters thereof
TW200604137A (en) 2004-04-27 2006-02-01 Wyeth Corp Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls

Also Published As

Publication number Publication date
WO2005105817A3 (en) 2006-01-12
AR049631A1 (es) 2006-08-23
US20050272702A1 (en) 2005-12-08
US20090054663A1 (en) 2009-02-26
SV2005002092A (es) 2005-12-13
US7446211B2 (en) 2008-11-04
WO2005105817A2 (en) 2005-11-10
PE20060331A1 (es) 2006-05-16
TW200604137A (en) 2006-02-01
US8129523B2 (en) 2012-03-06

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