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TW200604137A - Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls - Google Patents

Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls

Info

Publication number
TW200604137A
TW200604137A TW094113123A TW94113123A TW200604137A TW 200604137 A TW200604137 A TW 200604137A TW 094113123 A TW094113123 A TW 094113123A TW 94113123 A TW94113123 A TW 94113123A TW 200604137 A TW200604137 A TW 200604137A
Authority
TW
Taiwan
Prior art keywords
carbonitriles
boron
coupling process
containing derivatives
substituted pyrrole
Prior art date
Application number
TW094113123A
Other languages
English (en)
Inventor
Bogdan Kazimierz Wilk
Arkadiy Zinoviy Rubezhov
Jean Louise Helom
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of TW200604137A publication Critical patent/TW200604137A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW094113123A 2004-04-27 2005-04-25 Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls TW200604137A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56563604P 2004-04-27 2004-04-27
US64765605P 2005-01-27 2005-01-27

Publications (1)

Publication Number Publication Date
TW200604137A true TW200604137A (en) 2006-02-01

Family

ID=34967855

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094113123A TW200604137A (en) 2004-04-27 2005-04-25 Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls

Country Status (7)

Country Link
US (2) US7446211B2 (zh)
AR (1) AR049631A1 (zh)
PA (1) PA8631101A1 (zh)
PE (1) PE20060331A1 (zh)
SV (1) SV2005002092A (zh)
TW (1) TW200604137A (zh)
WO (1) WO2005105817A2 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2306140T3 (es) 2004-04-27 2008-11-01 Wyeth Biarilos ciclicos de carbamato y tiocarbamato que contienen cianopirrol y procedimientos para su preparacion.
PE20060331A1 (es) 2004-04-27 2006-05-16 Wyeth Corp Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
PT1778710E (pt) * 2004-08-13 2012-04-12 Wyeth Llc Derivados de tanaproget, metabolitos e suas utilizações
CN101166532B (zh) 2005-04-28 2011-06-22 惠氏公司 微粒化的他那普戈特、组合物及其制备方法
CN101166736B (zh) 2005-04-28 2013-02-06 惠氏公司 他那普戈特的多晶型ⅱ
ES2340518T3 (es) 2005-04-28 2010-06-04 Wyeth Llc Tanaproget micronizado y composiciones que lo contienen.
ES2431324T3 (es) * 2005-04-28 2013-11-26 Wyeth Llc Forma purificada de tanaproget
PE20070220A1 (es) 2005-07-29 2007-03-19 Wyeth Corp Proceso para la sintesis de moduladores del receptor de progesterona
US20070213526A1 (en) * 2006-03-07 2007-09-13 Wyeth Purification of progesterone receptor modulators
JP5428341B2 (ja) 2007-01-29 2014-02-26 和光純薬工業株式会社 有機トリオールボレート塩を含んでなる有機合成反応用試薬
US20080319204A1 (en) * 2007-06-25 2008-12-25 Wyeth Process for the synthesis of progesterone receptor modulators
BRPI0819571A2 (pt) * 2007-12-20 2019-09-24 Teva Womenss Health Inc "método para contracepção de emergência, pacote farmacêutico para contracepção de emergência e composição farmacêutica"
IL297898A (en) 2020-05-05 2023-01-01 Nuvalent Inc Heteroaromatic macrocyclic ether chemotherapeutic agents
AU2021268664A1 (en) 2020-05-05 2022-10-20 Nuvalent, Inc. Heteroaromatic macrocyclic ether chemotherapeutic agents
IL311444A (en) 2021-10-01 2024-05-01 Nuvalent Inc Solid forms, pharmaceutical compositions and preparation of heteroaromatic macrocyclic ether compounds

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JPH09502432A (ja) 1993-09-10 1997-03-11 チバ−ガイギー アクチエンゲゼルシャフト フォトクロミック化合物、その製造方法および製造のための中間生成物、ならびにそれらの用法
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Also Published As

Publication number Publication date
US7446211B2 (en) 2008-11-04
US20050272702A1 (en) 2005-12-08
WO2005105817A3 (en) 2006-01-12
SV2005002092A (es) 2005-12-13
US8129523B2 (en) 2012-03-06
PA8631101A1 (es) 2006-09-08
PE20060331A1 (es) 2006-05-16
WO2005105817A2 (en) 2005-11-10
AR049631A1 (es) 2006-08-23
US20090054663A1 (en) 2009-02-26

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