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FI20085807L - Förfarande för tillverkning av escitalopram - Google Patents

Förfarande för tillverkning av escitalopram Download PDF

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Publication number
FI20085807L
FI20085807L FI20085807A FI20085807A FI20085807L FI 20085807 L FI20085807 L FI 20085807L FI 20085807 A FI20085807 A FI 20085807A FI 20085807 A FI20085807 A FI 20085807A FI 20085807 L FI20085807 L FI 20085807L
Authority
FI
Finland
Prior art keywords
preparing escitalopram
escitalopram
preparing
Prior art date
Application number
FI20085807A
Other languages
English (en)
Finnish (fi)
Other versions
FI20085807A0 (sv
FI121570B (sv
Inventor
Carla Defaveri
Florian Anton Martin Huber
Robert Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735675&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI20085807(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of FI20085807A0 publication Critical patent/FI20085807A0/sv
Publication of FI20085807L publication Critical patent/FI20085807L/sv
Application granted granted Critical
Publication of FI121570B publication Critical patent/FI121570B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/32Separation; Purification; Stabilisation; Use of additives
    • C07C253/34Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI20085807A 2007-09-11 2008-08-29 Förfarande för tillverkning av escitalopram FI121570B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK200701314 2007-09-11
DKPA200701314 2007-09-11

Publications (3)

Publication Number Publication Date
FI20085807A0 FI20085807A0 (sv) 2008-08-29
FI20085807L true FI20085807L (sv) 2009-03-12
FI121570B FI121570B (sv) 2011-01-14

Family

ID=39735675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20085807A FI121570B (sv) 2007-09-11 2008-08-29 Förfarande för tillverkning av escitalopram

Country Status (52)

Country Link
EP (2) EP2397461A1 (sv)
JP (1) JP4966933B2 (sv)
KR (1) KR101054224B1 (sv)
CN (1) CN101386583A (sv)
AR (2) AR068174A1 (sv)
AT (2) ATE518829T1 (sv)
AU (1) AU2008212055C1 (sv)
BE (1) BE1017548A6 (sv)
BG (1) BG110206A (sv)
BR (1) BRPI0804121B1 (sv)
CA (1) CA2638499C (sv)
CH (1) CH697885B1 (sv)
CL (1) CL2008002686A1 (sv)
CO (1) CO6140012A1 (sv)
CY (2) CY2600B1 (sv)
CZ (1) CZ2008537A3 (sv)
DE (1) DE102008046530A1 (sv)
DK (2) DK2061753T3 (sv)
EA (1) EA012787B1 (sv)
EE (1) EE00864U1 (sv)
ES (2) ES2334875B1 (sv)
FI (1) FI121570B (sv)
FR (1) FR2920766A1 (sv)
GB (1) GB2448848B (sv)
GR (1) GR1006595B (sv)
HR (2) HRP20080425A2 (sv)
HU (1) HUP0800549A2 (sv)
IE (1) IES20080708A2 (sv)
IL (1) IL193845A (sv)
IS (1) IS8758A (sv)
LT (1) LT5577B (sv)
LU (1) LU91479B1 (sv)
LV (1) LV13813B (sv)
ME (1) ME00176B (sv)
MX (1) MX2008011451A (sv)
MY (1) MY144210A (sv)
NL (1) NL2001953C2 (sv)
NO (1) NO20083756L (sv)
NZ (1) NZ570884A (sv)
PL (2) PL386026A1 (sv)
PT (2) PT104169A (sv)
RO (1) RO125301A2 (sv)
RS (2) RS20080401A (sv)
SE (1) SE533041C2 (sv)
SG (1) SG151195A1 (sv)
SI (2) SI22567A2 (sv)
SK (1) SK500302008A3 (sv)
TR (2) TR200806903A2 (sv)
TW (1) TWI391383B (sv)
UA (2) UA43461U (sv)
WO (1) WO2009033488A1 (sv)
ZA (1) ZA200807753B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1987016A1 (en) 2005-07-27 2008-11-05 Aurobindo Pharma Limited An improved process for the preparation of escitalopram
CN102796065A (zh) * 2011-05-27 2012-11-28 江苏豪森医药集团连云港宏创医药有限公司 一种制备光学纯度高的艾司西酞普兰的方法
CN104119240A (zh) * 2013-04-23 2014-10-29 中国人民解放军军事医学科学院毒物药物研究所 (S)-(-)-α-甲胺基苯丙酮的制备方法
CN103497145B (zh) * 2013-10-10 2016-01-27 南昌大学 一种光学纯多奈哌齐的制备工艺
CN104119248A (zh) * 2014-08-08 2014-10-29 广东东阳光药业有限公司 S-西酞普兰的制备方法
WO2016074225A1 (zh) * 2014-11-14 2016-05-19 浙江华海药业股份有限公司 一种拆分西酞普兰中间体5-氰二醇的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
AR034612A1 (es) 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) * 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
CA2511143C (en) 2002-12-23 2011-06-28 H. Lundbeck A/S Preparation of racemic and/or s- or r-citalopram diols and their use for the preparation racemic and/or s- or r-citalopram
WO2004065375A1 (en) * 2003-01-17 2004-08-05 Natco Pharma Limited Processes for the preparation of escitalopram and its precursor
WO2005047274A1 (en) * 2003-11-12 2005-05-26 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
EP1877394A1 (en) * 2005-04-04 2008-01-16 Jubilant Organosys Limited Process for the preparation of escitalopram or its acid addition salts
EP1987016A1 (en) * 2005-07-27 2008-11-05 Aurobindo Pharma Limited An improved process for the preparation of escitalopram

Also Published As

Publication number Publication date
TWI391383B (zh) 2013-04-01
UA41919U (uk) 2009-06-10
NZ570884A (en) 2010-03-26
LV13813B (en) 2008-11-20
CL2008002686A1 (es) 2009-01-02
EA012787B1 (ru) 2009-12-30
PT2061753E (pt) 2011-09-14
KR101054224B1 (ko) 2011-08-08
AU2008212055A1 (en) 2009-03-26
BE1017548A6 (fr) 2008-11-04
NL2001953A1 (nl) 2008-12-22
EP2397461A1 (en) 2011-12-21
SE533041C2 (sv) 2010-06-15
EE00864U1 (et) 2009-10-15
ATE518829T1 (de) 2011-08-15
RS51909B (sr) 2012-02-29
EA200801797A3 (ru) 2009-02-27
EP2061753B1 (en) 2011-08-03
PT104169A (pt) 2009-02-02
GR1006595B (el) 2009-11-16
BRPI0804121A2 (pt) 2009-09-29
FI20085807A0 (sv) 2008-08-29
JP2009149600A (ja) 2009-07-09
AT10984U1 (de) 2010-02-15
CY2600B1 (en) 2010-03-03
CA2638499A1 (en) 2008-11-21
CA2638499C (en) 2010-09-28
TW200906814A (en) 2009-02-16
TR200806903A2 (tr) 2009-03-23
AR108885A2 (es) 2018-10-03
CN101386583A (zh) 2009-03-18
BRPI0804121A8 (pt) 2021-04-13
GB0815773D0 (en) 2008-10-08
DE102008046530A1 (de) 2009-03-19
LU91479B1 (fr) 2010-03-11
AU2008212055C1 (en) 2011-06-02
MEP10108A (bs) 2010-10-10
AR068174A1 (es) 2009-11-11
BG110206A (en) 2009-03-31
KR20090027185A (ko) 2009-03-16
PL386026A1 (pl) 2009-02-16
RO125301A2 (ro) 2010-03-30
ME00176B (me) 2011-02-10
MX2008011451A (es) 2009-03-10
EA200801797A2 (ru) 2008-12-30
ZA200807753B (en) 2009-04-29
SI2061753T1 (sl) 2011-10-28
FI121570B (sv) 2011-01-14
GB2448848A (en) 2008-10-29
CO6140012A1 (es) 2010-03-19
BRPI0804121B1 (pt) 2022-04-12
LT5577B (lt) 2009-06-25
CH697885B1 (de) 2009-03-13
DK2061753T3 (da) 2011-09-26
IL193845A (en) 2011-03-31
JP4966933B2 (ja) 2012-07-04
FR2920766A1 (fr) 2009-03-13
EP2061753A1 (en) 2009-05-27
HUP0800549A2 (en) 2009-03-02
GB2448848B (en) 2011-01-26
HU0800549D0 (en) 2008-10-28
CY1111924T1 (el) 2015-11-04
ES2334875B1 (es) 2010-10-27
SK500302008A3 (sk) 2009-04-06
DK200801265A (en) 2009-03-12
SI22567A2 (sl) 2008-12-31
RS20080401A (sr) 2010-03-02
SE0801929L (sv) 2009-03-12
UA43461U (uk) 2009-08-25
AU2008212055B2 (en) 2010-08-12
NL2001953C2 (en) 2009-05-07
HRP20110636T1 (hr) 2011-10-31
HRP20080425A2 (hr) 2010-04-30
DK177075B1 (da) 2011-06-14
LT2008068A (en) 2009-03-25
MY144210A (en) 2011-08-15
ES2334875A1 (es) 2010-03-16
ES2368294T3 (es) 2011-11-16
PL2061753T3 (pl) 2011-12-30
NO20083756L (no) 2009-03-12
IS8758A (is) 2009-03-12
WO2009033488A1 (en) 2009-03-19
GR20080100581A (el) 2009-04-30
CZ2008537A3 (cs) 2009-03-18
IES20080708A2 (en) 2009-03-18
TR200907629A2 (tr) 2009-11-23
SG151195A1 (en) 2009-04-30

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