DK3297653T3 - Behandling af postbariatrisk hypoglykæmi med glp-1-antagonister - Google Patents

Behandling af postbariatrisk hypoglykæmi med glp-1-antagonister Download PDF

Info

Publication number: DK3297653T3
Authority: DK; Denmark
Prior art keywords: postbariatric; hypoglychemism; glp; antagonists; treatment
Prior art date: 2015-05-22

Application number

DK16800620.3T

Other languages

English (en)

Inventor

Tracey L Mclaughlin

Colleen M Craig

Original Assignee

Univ Leland Stanford Junior

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-05-22

Filing date

2016-05-23

Publication date

2021-10-18

2016-05-23 Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior

2021-10-18 Application granted granted Critical

2021-10-18 Publication of DK3297653T3 publication Critical patent/DK3297653T3/da

Links

102100025101 GATA-type zinc finger protein 1 Human genes 0.000 title 1
101710198884 GATA-type zinc finger protein 1 Proteins 0.000 title 1
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title 1
239000005557 antagonist Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Dispersion Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

DK16800620.3T 2015-05-22 2016-05-23 Behandling af postbariatrisk hypoglykæmi med glp-1-antagonister DK3297653T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201562165743P	2015-05-22	2015-05-22
US201562254175P	2015-11-11	2015-11-11
US201662329850P	2016-04-29	2016-04-29
PCT/US2016/033836 WO2016191394A1 (en)	2015-05-22	2016-05-23	Treatment of post-bariatric hypoglycemia with glp-1 antagonists

Publications (1)

Publication Number	Publication Date
DK3297653T3 true DK3297653T3 (da)	2021-10-18

Family

ID=57393681

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK16800621.1T DK3297654T3 (da)	2015-05-22	2016-05-23	Behandling af post-bariatrisk hypoglykæmi med exendin(9-39)
DK16800620.3T DK3297653T3 (da)	2015-05-22	2016-05-23	Behandling af postbariatrisk hypoglykæmi med glp-1-antagonister

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK16800621.1T DK3297654T3 (da)	2015-05-22	2016-05-23	Behandling af post-bariatrisk hypoglykæmi med exendin(9-39)

Country Status (18)

Country	Link
US (10)	US10639354B2 (da)
EP (4)	EP3297653B1 (da)
AU (6)	AU2016267052B2 (da)
BR (2)	BR112017024997A2 (da)
CA (2)	CA3024353A1 (da)
CL (2)	CL2017002911A1 (da)
CY (2)	CY1124616T1 (da)
DK (2)	DK3297654T3 (da)
ES (2)	ES2887723T3 (da)
HR (2)	HRP20211768T1 (da)
HU (2)	HUE057301T2 (da)
LT (2)	LT3297654T (da)
PL (2)	PL3297654T3 (da)
PT (2)	PT3297653T (da)
RS (2)	RS62368B1 (da)
SI (2)	SI3297654T1 (da)
SM (2)	SMT202100668T1 (da)
WO (2)	WO2016191395A1 (da)

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US11311519B2 (en)	2014-05-01	2022-04-26	Eiger Biopharmaceuticals, Inc.	Treatment of hepatitis delta virus infection
AU2016267052B2 (en)	2015-05-22	2022-01-20	The Bot Of The Leland Stanford Junior University	Treatment of post-bariatric hypoglycemia with GLP-1 antagonists
WO2017152014A1 (en)	2016-03-04	2017-09-08	Eiger Biopharmaceuticals, Inc.	Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives
EP3541366B1 (en)	2016-11-21	2024-12-25	Amylyx Pharmaceuticals, Inc.	Buffered formulations of exendin (9-39)
JP7444786B2 (ja) *	2018-01-23	2024-03-06	ゼリスファーマシューティカルズインコーポレイテッド	低用量の安定なグルカゴンを使用する肥満治療手術後の低血糖症の処置
GB201816639D0 (en) *	2018-10-12	2018-11-28	Heptares Therapeutics Ltd	GLP-1 Receptor Antagonist
AU2019359807B2 (en) *	2018-10-15	2025-04-24	Amylyx Pharmaceuticals, Inc.	Avexitide for the treatment of hyperinsulinemic hypoglycemia
EP3908274A1 (en) *	2019-01-11	2021-11-17	Universitätsspital Basel	Sglt-2 inhibitors or il-1r antagonists for reduction of hypoglycaemia after bariatric surgery
WO2024042518A1 (en) *	2022-08-21	2024-02-29	M. Arkin (1999) Ltd	Glp-1 receptor antagonist and methods of use thereof

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2016
- 2016-05-23 AU AU2016267052A patent/AU2016267052B2/en active Active
- 2016-05-23 PT PT16800620T patent/PT3297653T/pt unknown
- 2016-05-23 WO PCT/US2016/033837 patent/WO2016191395A1/en not_active Ceased
- 2016-05-23 BR BR112017024997-9A patent/BR112017024997A2/pt not_active Application Discontinuation
- 2016-05-23 WO PCT/US2016/033836 patent/WO2016191394A1/en not_active Ceased
- 2016-05-23 US US15/576,647 patent/US10639354B2/en active Active
- 2016-05-23 EP EP16800620.3A patent/EP3297653B1/en active Active
- 2016-05-23 ES ES16800621T patent/ES2887723T3/es active Active
- 2016-05-23 PL PL16800621T patent/PL3297654T3/pl unknown
- 2016-05-23 EP EP21176474.1A patent/EP3936143A1/en active Pending
- 2016-05-23 CA CA3024353A patent/CA3024353A1/en active Pending
- 2016-05-23 AU AU2016267057A patent/AU2016267057B2/en active Active
- 2016-05-23 LT LTEPPCT/US2016/033837T patent/LT3297654T/lt unknown
- 2016-05-23 EP EP16800621.1A patent/EP3297654B1/en active Active
- 2016-05-23 DK DK16800621.1T patent/DK3297654T3/da active
- 2016-05-23 LT LTEPPCT/US2016/033836T patent/LT3297653T/lt unknown
- 2016-05-23 SM SM20210668T patent/SMT202100668T1/it unknown
- 2016-05-23 HU HUE16800620A patent/HUE057301T2/hu unknown
- 2016-05-23 PL PL16800620T patent/PL3297653T3/pl unknown
- 2016-05-23 ES ES16800620T patent/ES2897955T3/es active Active
- 2016-05-23 SI SI201631300T patent/SI3297654T1/sl unknown
- 2016-05-23 SI SI201631362T patent/SI3297653T1/sl unknown
- 2016-05-23 BR BR112017025000-4A patent/BR112017025000A2/pt not_active Application Discontinuation
- 2016-05-23 EP EP21194982.1A patent/EP3978011A1/en active Pending
- 2016-05-23 PT PT168006211T patent/PT3297654T/pt unknown
- 2016-05-23 CA CA3024358A patent/CA3024358A1/en active Pending
- 2016-05-23 RS RS20211073A patent/RS62368B1/sr unknown
- 2016-05-23 HR HRP20211768TT patent/HRP20211768T1/hr unknown
- 2016-05-23 SM SM20210488T patent/SMT202100488T1/it unknown
- 2016-05-23 HU HUE16800621A patent/HUE055728T2/hu unknown
- 2016-05-23 US US15/576,646 patent/US10660937B2/en active Active
- 2016-05-23 HR HRP20211285TT patent/HRP20211285T1/hr unknown
- 2016-05-23 DK DK16800620.3T patent/DK3297653T3/da active
- 2016-05-23 RS RS20211458A patent/RS62627B1/sr unknown
2017
- 2017-11-16 CL CL2017002911A patent/CL2017002911A1/es unknown
- 2017-11-16 CL CL2017002913A patent/CL2017002913A1/es unknown
2020
- 2020-03-09 US US16/813,536 patent/US10993992B2/en active Active
- 2020-03-09 US US16/813,535 patent/US10993991B2/en active Active
2021
- 2021-04-09 US US17/226,164 patent/US11617782B2/en active Active
- 2021-04-09 US US17/226,161 patent/US11622995B2/en active Active
- 2021-09-01 CY CY20211100779T patent/CY1124616T1/el unknown
- 2021-11-29 CY CY20211101046T patent/CY1125147T1/el unknown
2022
- 2022-03-22 AU AU2022201973A patent/AU2022201973B2/en active Active
- 2022-04-14 AU AU2022202506A patent/AU2022202506B2/en active Active
2023
- 2023-02-22 US US18/172,543 patent/US12220444B2/en active Active
- 2023-02-22 US US18/172,546 patent/US12102663B2/en active Active
2024
- 2024-06-17 US US18/745,091 patent/US20250082730A1/en active Pending
2025
- 2025-01-02 US US19/008,248 patent/US20250255935A1/en active Pending
- 2025-08-13 AU AU2025217292A patent/AU2025217292A1/en active Pending
- 2025-08-22 AU AU2025220813A patent/AU2025220813A1/en active Pending

Also Published As

Publication number	Publication date
US20180117122A1 (en)	2018-05-03
SI3297654T1 (sl)	2021-11-30
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