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DK3236960T3 - Fluralaner til anvendelse i behandling af demodicose - Google Patents

Fluralaner til anvendelse i behandling af demodicose Download PDF

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Publication number
DK3236960T3
DK3236960T3 DK15817303.9T DK15817303T DK3236960T3 DK 3236960 T3 DK3236960 T3 DK 3236960T3 DK 15817303 T DK15817303 T DK 15817303T DK 3236960 T3 DK3236960 T3 DK 3236960T3
Authority
DK
Denmark
Prior art keywords
fluralan
demodicose
treatment
Prior art date
Application number
DK15817303.9T
Other languages
English (en)
Inventor
Heike Williams
Anja Regina Heckeroth
Janina Tänzler
Régis Joël Alain Frenais
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Application granted granted Critical
Publication of DK3236960T3 publication Critical patent/DK3236960T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK15817303.9T 2014-12-22 2015-12-21 Fluralaner til anvendelse i behandling af demodicose DK3236960T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14199562 2014-12-22
PCT/EP2015/080744 WO2016102437A1 (en) 2014-12-22 2015-12-21 Use of isoxazoline compounds for treating demodicosis

Publications (1)

Publication Number Publication Date
DK3236960T3 true DK3236960T3 (da) 2025-03-31

Family

ID=52146273

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15817303.9T DK3236960T3 (da) 2014-12-22 2015-12-21 Fluralaner til anvendelse i behandling af demodicose
DK21213190.8T DK4008329T3 (da) 2014-12-22 2015-12-21 Isoxazolinforbindelser til anvendelse i behandling af demodicose

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK21213190.8T DK4008329T3 (da) 2014-12-22 2015-12-21 Isoxazolinforbindelser til anvendelse i behandling af demodicose

Country Status (14)

Country Link
US (3) US20170348286A1 (da)
EP (3) EP4008329B1 (da)
JP (1) JP6706262B2 (da)
CN (2) CN114681453A (da)
AU (3) AU2015371175B2 (da)
BR (1) BR112017013286A2 (da)
CA (1) CA2971296A1 (da)
DK (2) DK3236960T3 (da)
ES (2) ES3018234T3 (da)
FI (2) FI4008329T3 (da)
PL (2) PL3236960T3 (da)
PT (2) PT3236960T (da)
RU (1) RU2709198C2 (da)
WO (1) WO2016102437A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
DK3236960T3 (da) 2014-12-22 2025-03-31 Intervet Int Bv Fluralaner til anvendelse i behandling af demodicose
WO2018039508A1 (en) * 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN107501199A (zh) * 2017-08-16 2017-12-22 南京农业大学 氟雷拉纳单体化合物的提取和纯化方法
ES2981130T3 (es) * 2017-12-15 2024-10-07 Tarsus Pharmaceuticals Inc Formulaciones de parasiticida de isoxazolina y su uso para tratar blefaritis
US11880349B2 (en) 2019-04-30 2024-01-23 Salesforce, Inc. System or method to query or search a metadata driven distributed ledger or blockchain
CA3185969A1 (en) 2020-07-24 2022-01-27 Jean Marie Defauw Process for making an isoxazoline compound and intermediate thereof
CN115785017B (zh) * 2022-12-06 2023-12-08 海利尔药业集团股份有限公司 一种取代的苯酰胺异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2067863C1 (ru) * 1994-05-25 1996-10-20 Казанский государственный технологический университет Акарицидный состав для лечения чесотки домашних животных
SI1731512T1 (sl) 2004-03-05 2015-01-30 Nissan Chemical Industries, Ltd. Z izoksazolinom substituirana benzamidna spojina in sredstvo za uravnavanje škodljivih organizmov
DE102004053964A1 (de) * 2004-11-09 2006-05-11 Bayer Healthcare Ag Mittel gegen Demodikose
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
WO2009003075A1 (en) 2007-06-27 2008-12-31 E.I. Du Pont De Nemours And Company Animal pest control method
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
WO2010079077A1 (en) 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
CA2747354C (en) 2008-12-19 2016-12-06 Novartis Ag Isoxazoline derivatives and their use as pesticide
KR101992589B1 (ko) 2010-12-27 2019-06-24 인터벳 인터내셔널 비.브이. 글리코푸롤을 포함하는 국소 적용 이속사졸린 제제
CA2822839C (en) 2010-12-27 2020-12-29 Intervet International B.V. Topical localized isoxazoline formulation
EP2683723B1 (en) * 2011-03-10 2016-05-25 Zoetis Services LLC Spirocyclic isoxazoline derivatives as antiparasitic agents
LT2755473T (lt) * 2011-09-12 2019-03-12 Merial, Inc. Paraziticidinės kompozicijos, apimančios izoksazolino veiklųjį agentą, būdai ir jų panaudojimai
MD4577C1 (ro) 2012-02-06 2019-02-28 Merial Inc. Compoziţii masticabile de uz veterinar care conţin agent activ izoxazolinic şi utilizarea acestora în tratamentul sau prevenirea unei infestări sau infecţii parazitare
US9770440B2 (en) 2012-04-04 2017-09-26 Intervet Inc. Solid oral pharmaceutical compositions for isoxazoline compounds
WO2014090918A1 (en) * 2012-12-13 2014-06-19 Novartis Ag Process for the enantiomeric enrichment of diaryloxazoline derivatives
EP4306168B1 (en) * 2013-12-20 2025-06-25 Intervet International B.V. Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals
DK3236960T3 (da) 2014-12-22 2025-03-31 Intervet Int Bv Fluralaner til anvendelse i behandling af demodicose

Also Published As

Publication number Publication date
US10799483B2 (en) 2020-10-13
FI4008329T3 (fi) 2025-08-22
RU2017126029A (ru) 2019-01-24
AU2023219972B2 (en) 2025-05-29
WO2016102437A1 (en) 2016-06-30
ES3018234T3 (en) 2025-05-14
PT3236960T (pt) 2025-04-08
EP4599830A2 (en) 2025-08-13
AU2015371175B2 (en) 2021-03-04
US20200405692A1 (en) 2020-12-31
EP4008329A1 (en) 2022-06-08
BR112017013286A2 (pt) 2018-03-06
RU2017126029A3 (da) 2019-06-20
EP4599830A3 (en) 2025-11-19
US20180318265A1 (en) 2018-11-08
EP3236960A1 (en) 2017-11-01
DK4008329T3 (da) 2025-08-18
CN106999475B (zh) 2022-10-25
JP6706262B2 (ja) 2020-06-03
PL3236960T3 (pl) 2025-07-07
CN106999475A (zh) 2017-08-01
RU2709198C2 (ru) 2019-12-17
CN114681453A (zh) 2022-07-01
PL4008329T3 (pl) 2025-11-17
JP2017538767A (ja) 2017-12-28
AU2023219972A1 (en) 2023-09-14
CA2971296A1 (en) 2016-06-30
EP4008329B1 (en) 2025-06-11
FI3236960T3 (fi) 2025-04-05
US20170348286A1 (en) 2017-12-07
ES3037078T3 (en) 2025-09-26
PT4008329T (pt) 2025-07-30
EP3236960B1 (en) 2025-01-29
AU2021203686A1 (en) 2021-07-01
AU2015371175A1 (en) 2017-06-15

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DK3236960T3 (da) Fluralaner til anvendelse i behandling af demodicose