DK3250600T3 - Behandling af autoimmune lidelser med cd154-antistoffer - Google Patents
Behandling af autoimmune lidelser med cd154-antistoffer Download PDFInfo
- Publication number
- DK3250600T3 DK3250600T3 DK15719675.9T DK15719675T DK3250600T3 DK 3250600 T3 DK3250600 T3 DK 3250600T3 DK 15719675 T DK15719675 T DK 15719675T DK 3250600 T3 DK3250600 T3 DK 3250600T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies
- treatment
- autoimmune diseases
- autoimmune
- diseases
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1501613.2A GB201501613D0 (en) | 2015-01-30 | 2015-01-30 | Treatment of autoimmune disorders with CD154 antibodies |
| PCT/EP2015/059095 WO2016119909A1 (en) | 2015-01-30 | 2015-04-27 | Treatment of autoimmune disorders with cd154 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3250600T3 true DK3250600T3 (da) | 2020-06-08 |
Family
ID=52705552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15719675.9T DK3250600T3 (da) | 2015-01-30 | 2015-04-27 | Behandling af autoimmune lidelser med cd154-antistoffer |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20180022812A1 (da) |
| EP (2) | EP3744735A1 (da) |
| KR (1) | KR102543877B1 (da) |
| CN (1) | CN107206075A (da) |
| AU (2) | AU2015379642B2 (da) |
| CA (1) | CA2975336C (da) |
| CY (1) | CY1123116T1 (da) |
| DK (1) | DK3250600T3 (da) |
| ES (1) | ES2802982T3 (da) |
| GB (1) | GB201501613D0 (da) |
| HR (1) | HRP20201013T1 (da) |
| HU (1) | HUE050024T2 (da) |
| LT (1) | LT3250600T (da) |
| PL (1) | PL3250600T3 (da) |
| PT (1) | PT3250600T (da) |
| RS (1) | RS60575B1 (da) |
| RU (1) | RU2695443C2 (da) |
| SI (1) | SI3250600T1 (da) |
| SM (1) | SMT202000369T1 (da) |
| WO (1) | WO2016119909A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE065915T2 (hu) | 2011-03-11 | 2024-06-28 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antitestek és alkalmazásaik |
| EP3307322B1 (en) | 2015-09-04 | 2021-02-17 | Primatope Therapeutics Inc. | Humanized anti-cd40 antibodies and uses thereof |
| WO2017148904A1 (en) * | 2016-02-29 | 2017-09-08 | Franz Grus | Predictive markers useful in the treatment of wet age-related macular degeneration |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US20210317220A1 (en) * | 2018-09-24 | 2021-10-14 | Janssen Biotech, Inc. | Method of providing safe administration of an anti-cd154 antibody |
| CN113447659B (zh) * | 2021-07-01 | 2022-05-17 | 浙江大学 | 一种检测抗蛋白酶体亚基α1-IgG抗体的试剂盒 |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| WO2023099607A1 (en) * | 2021-12-01 | 2023-06-08 | UCB Biopharma SRL | Formulations comprising fab-peg |
| WO2024222895A1 (zh) * | 2023-04-28 | 2024-10-31 | 信达生物制药(苏州)有限公司 | 抗cd40l抗体及其在人自身免疫疾病治疗的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| AU8867501A (en) * | 2000-09-01 | 2002-03-13 | Biogen Inc | Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| US7563443B2 (en) | 2004-09-17 | 2009-07-21 | Domantis Limited | Monovalent anti-CD40L antibody polypeptides and compositions thereof |
| PL2125894T3 (pl) * | 2007-03-22 | 2019-08-30 | Biogen Ma Inc. | Białka wiążące, w tym przeciwciała, pochodne przeciwciał i fragmenty przeciwciał, które swoiście wiążą się z CD154 i ich zastosowania |
| ES2650267T3 (es) * | 2008-12-05 | 2018-01-17 | Als Therapy Development Institute | Método para el tratamiento de enfermedades neurodegenerativas |
| AR083847A1 (es) * | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| CA2834203A1 (en) * | 2011-04-26 | 2012-11-01 | Genentech, Inc. | Compositions and method for treating autoimmune diseases |
-
2015
- 2015-01-30 GB GBGB1501613.2A patent/GB201501613D0/en not_active Ceased
- 2015-04-27 ES ES15719675T patent/ES2802982T3/es active Active
- 2015-04-27 RU RU2017130464A patent/RU2695443C2/ru active
- 2015-04-27 SI SI201531299T patent/SI3250600T1/sl unknown
- 2015-04-27 KR KR1020177024036A patent/KR102543877B1/ko active Active
- 2015-04-27 LT LTEP15719675.9T patent/LT3250600T/lt unknown
- 2015-04-27 EP EP20172402.8A patent/EP3744735A1/en active Pending
- 2015-04-27 PL PL15719675T patent/PL3250600T3/pl unknown
- 2015-04-27 DK DK15719675.9T patent/DK3250600T3/da active
- 2015-04-27 AU AU2015379642A patent/AU2015379642B2/en active Active
- 2015-04-27 RS RS20200831A patent/RS60575B1/sr unknown
- 2015-04-27 WO PCT/EP2015/059095 patent/WO2016119909A1/en not_active Ceased
- 2015-04-27 CA CA2975336A patent/CA2975336C/en active Active
- 2015-04-27 CN CN201580074799.1A patent/CN107206075A/zh active Pending
- 2015-04-27 PT PT157196759T patent/PT3250600T/pt unknown
- 2015-04-27 HR HRP20201013TT patent/HRP20201013T1/hr unknown
- 2015-04-27 EP EP15719675.9A patent/EP3250600B1/en active Active
- 2015-04-27 SM SM20200369T patent/SMT202000369T1/it unknown
- 2015-04-27 HU HUE15719675A patent/HUE050024T2/hu unknown
- 2015-04-27 US US15/547,223 patent/US20180022812A1/en not_active Abandoned
-
2020
- 2020-07-10 CY CY20201100635T patent/CY1123116T1/el unknown
-
2021
- 2021-06-29 US US17/361,393 patent/US11884737B2/en active Active
-
2022
- 2022-01-19 AU AU2022200347A patent/AU2022200347A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL3250600T3 (pl) | 2020-09-21 |
| SI3250600T1 (sl) | 2020-09-30 |
| NZ733454A (en) | 2023-12-22 |
| CA2975336C (en) | 2022-10-18 |
| EP3250600A1 (en) | 2017-12-06 |
| ES2802982T3 (es) | 2021-01-22 |
| RU2017130464A3 (da) | 2019-02-28 |
| RU2017130464A (ru) | 2019-02-28 |
| AU2015379642A1 (en) | 2017-07-27 |
| US20180022812A1 (en) | 2018-01-25 |
| GB201501613D0 (en) | 2015-03-18 |
| EP3744735A1 (en) | 2020-12-02 |
| PT3250600T (pt) | 2020-06-17 |
| RS60575B1 (sr) | 2020-08-31 |
| CA2975336A1 (en) | 2016-08-04 |
| LT3250600T (lt) | 2020-07-27 |
| AU2015379642B2 (en) | 2021-11-04 |
| HUE050024T2 (hu) | 2020-11-30 |
| US11884737B2 (en) | 2024-01-30 |
| WO2016119909A1 (en) | 2016-08-04 |
| SMT202000369T1 (it) | 2020-09-10 |
| RU2695443C2 (ru) | 2019-07-23 |
| CN107206075A (zh) | 2017-09-26 |
| HRP20201013T1 (hr) | 2020-10-16 |
| US20210324095A1 (en) | 2021-10-21 |
| KR102543877B1 (ko) | 2023-06-14 |
| EP3250600B1 (en) | 2020-05-06 |
| AU2022200347A1 (en) | 2022-02-17 |
| CY1123116T1 (el) | 2021-10-29 |
| KR20170106476A (ko) | 2017-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL263690A (en) | Purification of multispecific antibodies | |
| DK3302565T3 (da) | Faste doseringsformer af palbociclib | |
| DK3390441T3 (da) | Antistoffer til neutralisering af human immundefekt virus | |
| DK3851537T5 (da) | Behandling af hyperbilirubinæmi | |
| DK3253865T3 (da) | Fremgangsmåder til forbedring af virkningen af terapeutiske immunceller | |
| DK3244948T3 (da) | Bestemmelse af medikamentdosis | |
| DK3212233T3 (da) | Kombinationsterapi til behandling af sygdom | |
| PL3353210T3 (pl) | Przeciwciała anty-TIGIT i sposoby stosowania | |
| DK3468997T5 (da) | Behandling af IgG4-relaterede sygdomme med anti-CD9-antistoffer med tværbinding til CD32B | |
| DK3137504T3 (da) | Antistofbinding til fcrn til behandling af autoimmunsygdomme | |
| DK3390390T3 (da) | Bipyrazolylderivater egnede til behandling af autoimmunsygdomme | |
| DK3250600T3 (da) | Behandling af autoimmune lidelser med cd154-antistoffer | |
| DK3099298T3 (da) | Kombinationsterapier med zidovudin til behandling af mikrobielle infektioner | |
| DK3240612T3 (da) | Fremgangsmåder til behandling af nethindesygdomme | |
| HUE045866T2 (hu) | CD30XCD16A antitest kombinálása anti-PD-1-antagonista antitesttel terápiához | |
| DK3609529T3 (da) | Rna til behandling af autoimmune sygdomme | |
| DK3182996T3 (da) | Fremgangsmåder til behandling af myelomatose med immunmodulatoriske forbindelser i kombination med antistoffer | |
| DK3865484T3 (da) | Pde9-hæmmer med imidazopyrazinon-rygrad til behandling af perifere sygdomme | |
| DK3297653T3 (da) | Behandling af postbariatrisk hypoglykæmi med glp-1-antagonister | |
| DK3612208T3 (da) | Coversin til behandlingen af autoimmune sygdomme med blisterdannelse | |
| DK3166628T3 (da) | Terapeutisk anvendelse af knoglemorfogenetiske proteiner | |
| DK3973959T3 (da) | Behandling af kolestatisk kløe med seladelpar | |
| DK3307267T3 (da) | Behandling af multipel sklerose | |
| DK3237621T3 (da) | Varianter af human alpha-galactosidase | |
| HUE063528T2 (hu) | Anti-CD40 antitestek alkalmazása lupus nephritis kezelésére |