DE69620191D1 - (1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol-methansulfonat trihydrat - Google Patents

(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol-methansulfonat trihydrat

Info

Publication number: DE69620191D1
Authority: DE; Germany
Prior art keywords: phenylpiperidin; hydroxyphenyl; propanol; hydroxy; methanesulfonate trihydrate
Prior art date: 1995-08-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69620191T

Other languages

English (en)

Other versions

DE69620191T2 (de

Inventor

M Andino

G Sinay

F Fiese

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp Belgium

Pfizer Inc

Original Assignee

Pfizer Corp Belgium

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-11

Filing date

1996-06-20

Publication date

2002-05-02

1996-06-20 Application filed by Pfizer Corp Belgium, Pfizer Inc filed Critical Pfizer Corp Belgium

2002-05-02 Publication of DE69620191D1 publication Critical patent/DE69620191D1/de

2002-07-18 Application granted granted Critical

2002-07-18 Publication of DE69620191T2 publication Critical patent/DE69620191T2/de

2016-06-21 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

DE69620191T 1995-08-11 1996-06-20 (1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol-methansulfonat trihydrat Expired - Fee Related DE69620191T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US223895P	1995-08-11	1995-08-11
PCT/IB1996/000592 WO1997007098A1 (en)	1995-08-11	1996-06-20	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanolmethanesulfonate trihydrate

Publications (2)

Publication Number	Publication Date
DE69620191D1 true DE69620191D1 (de)	2002-05-02
DE69620191T2 DE69620191T2 (de)	2002-07-18

Family

ID=21699847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69620191T Expired - Fee Related DE69620191T2 (de)	1995-08-11	1996-06-20	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol-methansulfonat trihydrat

Country Status (41)

Country	Link
US (1)	US6008233A (de)
EP (1)	EP0843661B1 (de)
JP (1)	JP3099072B2 (de)
KR (1)	KR100291882B1 (de)
CN (2)	CN1198739A (de)
AP (1)	AP755A (de)
AR (1)	AR004676A1 (de)
AT (1)	ATE215072T1 (de)
AU (1)	AU710984B2 (de)
BG (1)	BG63678B1 (de)
BR (1)	BR9610766A (de)
CA (1)	CA2228752C (de)
CO (1)	CO4750830A1 (de)
CZ (1)	CZ296236B6 (de)
DE (1)	DE69620191T2 (de)
DK (1)	DK0843661T3 (de)
DZ (1)	DZ2083A1 (de)
ES (1)	ES2170857T3 (de)
GT (1)	GT199600051A (de)
HR (1)	HRP960372B1 (de)
HU (1)	HUP9802862A3 (de)
IL (1)	IL122649A (de)
IS (1)	IS1945B (de)
MA (1)	MA23957A1 (de)
NO (1)	NO310458B1 (de)
NZ (1)	NZ309134A (de)
OA (1)	OA10664A (de)
PE (1)	PE4898A1 (de)
PL (1)	PL185603B1 (de)
PT (1)	PT843661E (de)
RO (1)	RO120134B1 (de)
RS (1)	RS49521B (de)
RU (1)	RU2140910C1 (de)
SA (1)	SA96170171B1 (de)
SK (1)	SK284209B6 (de)
TN (1)	TNSN96104A1 (de)
TR (1)	TR199800208T1 (de)
TW (1)	TW495502B (de)
UA (1)	UA59341C2 (de)
WO (1)	WO1997007098A1 (de)
ZA (1)	ZA966760B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0777652T3 (da) *	1994-08-18	2003-10-20	Pfizer	Neurobeskyttende 3-(piperidinyl-1)-chroman-4,7-diol-og 1-(4-hydrophenyl)-2-(piperidinyl-1)alkanolderivater
CA2228752C (en) *	1995-08-11	2002-12-10	Pfizer Inc.	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate
GB9820405D0 (en) *	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
CA2369695A1 (en) *	1999-04-09	2000-10-19	Manabu Itoh	Agent for treating neuropathic pain
GB9920919D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
GB9920917D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
US6620830B2 (en) *	2000-04-21	2003-09-16	Pfizer, Inc.	Thyroid receptor ligands
YU27701A (sh) *	2000-04-28	2003-04-30	Pfizer Products Inc.	Postupak za dobijanje trihidrata mezilatne soli 1-(4- hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)1-propanola
YU27801A (sh) *	2000-04-28	2003-04-30	Pfizer Products Inc.	Postupak za dobijanje trihidrata mezilatne soli 1-(4- hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)-1-propanola i korisnih intermedijera
CZ200380A3 (cs)	2000-08-16	2004-01-14	Pharmacia & Upjohn Company	Sloučeniny pro léčbu poruch spojených se závislostmi
EP1186303A3 (de) *	2000-09-06	2003-12-10	Pfizer Products Inc.	Ein Neutrophilhemmender Faktor und ein selektive NMDA-NR2B Rezeptor Antagonisten enthaltende Kombinationspräparate zur Behandlung von Schlaganfällen und traumatischen Gehirnschäden
IL145584A0 (en)	2000-10-02	2002-06-30	Pfizer Prod Inc	Nmda nr2b antagonists for treatment
EP1674087A1 (de)	2000-10-02	2006-06-28	Pfizer Products Inc.	Prophylaktische Verwendung von N-Methyl-D-Aspartat Rezeptor (NMDA) Antagonisten
UA73619C2 (en) *	2000-12-13	2005-08-15	Pfizer Prod Inc	Stable pharmaceutical compositions of nmda receptor agonist (variants) and method of treatment
MXPA04003541A (es)	2001-10-19	2004-07-22	Toyama Chemical Co Ltd	Derivados de eter alquilo o sus sales.
KR100517638B1 (ko)	2002-04-08	2005-09-28	주식회사 엘지생명과학	게미플록사신 산염의 새로운 제조방법
KR101052122B1 (ko)	2005-10-25	2011-07-26	시오노기세야쿠 가부시키가이샤	아미노디히드로티아진 유도체
MX2009011498A (es)	2007-04-24	2009-11-10	Shionogi & Co	Derivados de aminodihidrotiazina sustituida con un grupo ciclico.
WO2008133273A1 (ja)	2007-04-24	2008-11-06	Shionogi & Co., Ltd.	アルツハイマー症治療用医薬組成物
AU2009258496B8 (en)	2008-06-13	2014-06-26	Shionogi & Co., Ltd.	Sulfur-containing heterocyclic derivative having beta-secretase-inhibiting activity
JPWO2010047372A1 (ja)	2008-10-22	2012-03-22	塩野義製薬株式会社	Ｂａｃｅ１阻害活性を有する２−アミノピリミジン−４−オンおよび２−アミノピリジン誘導体
US8999980B2 (en)	2009-12-11	2015-04-07	Shionogi & Co., Ltd.	Oxazine derivatives
WO2012057247A1 (ja)	2010-10-29	2012-05-03	塩野義製薬株式会社	縮合アミノジヒドロピリミジン誘導体
US8927721B2 (en)	2010-10-29	2015-01-06	Shionogi & Co., Ltd.	Naphthyridine derivative
US8883779B2 (en)	2011-04-26	2014-11-11	Shinogi & Co., Ltd.	Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them
EP2912035A4 (de)	2012-10-24	2016-06-15	Shionogi & Co	Dihydrooxazin- oder oxazepinderivate mit bace1-hemmender wirkung
SG11201701853YA (en)	2014-09-15	2017-04-27	Rugen Holdings Cayman Ltd	Pyrrolopyrimidine derivatives as nr2b nmda receptor antagonists
EP3197440A4 (de) *	2014-09-22	2018-04-18	Rugen Holdings (Cayman) Limited	Behandlung von angstzuständen und störungen des autistischen spektrums
US10221182B2 (en)	2015-02-04	2019-03-05	Rugen Holdings (Cayman) Limited	3,3-difluoro-piperidine derivatives as NR2B NMDA receptor antagonists
CA2987606C (en)	2015-06-01	2024-02-20	Rugen Holdings (Cayman) Limited	3,3-difluoropiperidine carbamate heterocyclic compounds as nr2b nmda receptor antagonists
WO2018098128A1 (en)	2016-11-22	2018-05-31	Rugen Holdings (Cayman) Limited	Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK279476B6 (sk) *	1989-05-17	1998-11-04	Pfizer	Deriváty 2-piperidino a 2-pyrolidino-1-alkanolov a
US5272160A (en) *	1989-05-17	1993-12-21	Pfizer Inc	2-piperidino-1-alkanol derivatives as antiischemic agents
DK0777652T3 (da) *	1994-08-18	2003-10-20	Pfizer	Neurobeskyttende 3-(piperidinyl-1)-chroman-4,7-diol-og 1-(4-hydrophenyl)-2-(piperidinyl-1)alkanolderivater
CA2228752C (en) *	1995-08-11	2002-12-10	Pfizer Inc.	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate

1996
- 1996-06-20 CA CA002228752A patent/CA2228752C/en not_active Expired - Fee Related
- 1996-06-20 WO PCT/IB1996/000592 patent/WO1997007098A1/en not_active Ceased
- 1996-06-20 CN CN96195649A patent/CN1198739A/zh active Pending
- 1996-06-20 NZ NZ309134A patent/NZ309134A/en unknown
- 1996-06-20 DK DK96916266T patent/DK0843661T3/da active
- 1996-06-20 IL IL12264996A patent/IL122649A/xx not_active IP Right Cessation
- 1996-06-20 AU AU59084/96A patent/AU710984B2/en not_active Ceased
- 1996-06-20 SK SK166-98A patent/SK284209B6/sk unknown
- 1996-06-20 EP EP96916266A patent/EP0843661B1/de not_active Expired - Lifetime
- 1996-06-20 PT PT96916266T patent/PT843661E/pt unknown
- 1996-06-20 RU RU98102116A patent/RU2140910C1/ru not_active IP Right Cessation
- 1996-06-20 UA UA98020673A patent/UA59341C2/uk unknown
- 1996-06-20 JP JP09509083A patent/JP3099072B2/ja not_active Expired - Fee Related
- 1996-06-20 AT AT96916266T patent/ATE215072T1/de not_active IP Right Cessation
- 1996-06-20 TR TR1998/00208T patent/TR199800208T1/xx unknown
- 1996-06-20 RO RO98-00231A patent/RO120134B1/ro unknown
- 1996-06-20 CN CNA031584969A patent/CN1615861A/zh active Pending
- 1996-06-20 KR KR1019980700989A patent/KR100291882B1/ko not_active Expired - Fee Related
- 1996-06-20 ES ES96916266T patent/ES2170857T3/es not_active Expired - Lifetime
- 1996-06-20 DE DE69620191T patent/DE69620191T2/de not_active Expired - Fee Related
- 1996-06-20 US US09/011,426 patent/US6008233A/en not_active Expired - Fee Related
- 1996-06-20 CZ CZ0039098A patent/CZ296236B6/cs not_active IP Right Cessation
- 1996-06-20 HU HU9802862A patent/HUP9802862A3/hu unknown
- 1996-06-20 PL PL96325050A patent/PL185603B1/pl not_active IP Right Cessation
- 1996-06-20 BR BR9610766A patent/BR9610766A/pt not_active Application Discontinuation
- 1996-06-24 TW TW085107571A patent/TW495502B/zh not_active IP Right Cessation
- 1996-07-04 GT GT199600051A patent/GT199600051A/es unknown
- 1996-07-23 SA SA96170171A patent/SA96170171B1/ar unknown
- 1996-08-06 PE PE1996000587A patent/PE4898A1/es not_active Application Discontinuation
- 1996-08-07 DZ DZ960127A patent/DZ2083A1/fr active
- 1996-08-07 AR ARP960103904A patent/AR004676A1/es unknown
- 1996-08-07 TN TNTNSN96104A patent/TNSN96104A1/fr unknown
- 1996-08-07 MA MA24335A patent/MA23957A1/fr unknown
- 1996-08-08 ZA ZA9606760A patent/ZA966760B/xx unknown
- 1996-08-08 AP APAP/P/1996/000856A patent/AP755A/en active
- 1996-08-09 HR HR960372A patent/HRP960372B1/xx not_active IP Right Cessation
- 1996-08-09 RS YU46196A patent/RS49521B/sr unknown
- 1996-08-09 CO CO96042164A patent/CO4750830A1/es unknown
1997
- 1997-12-30 IS IS4643A patent/IS1945B/is unknown
1998
- 1998-02-10 NO NO19980574A patent/NO310458B1/no unknown
- 1998-02-10 OA OA9800021A patent/OA10664A/en unknown
- 1998-02-27 BG BG102289A patent/BG63678B1/bg unknown

Also Published As

Publication number	Publication date
UA59341C2 (uk)	2003-09-15
HRP960372A2 (en)	1998-04-30
TNSN96104A1 (fr)	2005-03-15
AR004676A1 (es)	1999-03-10
CZ296236B6 (cs)	2006-02-15
AP9600856A0 (en)	1996-10-31
IS4643A (is)	1997-12-30
NZ309134A (en)	1999-09-29
CZ39098A3 (cs)	1999-02-17
US6008233A (en)	1999-12-28
RS49521B (sr)	2006-10-27
MA23957A1 (fr)	1997-04-01
NO980574L (no)	1998-02-10
IL122649A0 (en)	1998-08-16
IS1945B (is)	2004-08-13
IL122649A (en)	2001-08-26
JP3099072B2 (ja)	2000-10-16
DZ2083A1 (fr)	2002-10-23
BR9610766A (pt)	1999-07-13
SK284209B6 (en)	2004-11-03
CN1198739A (zh)	1998-11-11
ZA966760B (en)	1998-02-09
AP755A (en)	1999-08-02
PE4898A1 (es)	1998-03-16
KR19990036321A (ko)	1999-05-25
KR100291882B1 (ko)	2001-10-26
DK0843661T3 (da)	2002-07-22
HRP960372B1 (en)	2003-04-30
SK16698A3 (en)	1999-06-11
CO4750830A1 (es)	1999-03-31
PT843661E (pt)	2002-07-31
JPH10510552A (ja)	1998-10-13
CN1615861A (zh)	2005-05-18
HUP9802862A2 (hu)	1999-04-28
ATE215072T1 (de)	2002-04-15
NO980574D0 (no)	1998-02-10
ES2170857T3 (es)	2002-08-16
EP0843661A1 (de)	1998-05-27
PL325050A1 (en)	1998-07-06
CA2228752A1 (en)	1997-02-27
AU710984B2 (en)	1999-10-07
CA2228752C (en)	2002-12-10
BG63678B1 (bg)	2002-09-30
GT199600051A (es)	1997-12-26
HUP9802862A3 (en)	1999-05-28
EP0843661B1 (de)	2002-03-27
TR199800208T1 (de)	1998-05-21
DE69620191T2 (de)	2002-07-18
AU5908496A (en)	1997-03-12
OA10664A (en)	2000-11-06
PL185603B1 (pl)	2003-06-30
RO120134B1 (ro)	2005-09-30
WO1997007098A1 (en)	1997-02-27
TW495502B (en)	2002-07-21
BG102289A (en)	1998-09-30
YU46196A (sh)	1999-07-28
RU2140910C1 (ru)	1999-11-10
MX9801149A (es)	1998-05-31
NO310458B1 (no)	2001-07-09
SA96170171B1 (ar)	2006-05-20

Publication	Publication Date	Title
DE69620191D1 (de)	2002-05-02	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol-methansulfonat trihydrat
ATE189812T1 (de)	2000-03-15	1-alpha, 26-dihydroxy-d-homo-vitamin d3
DE59607589D1 (de)	2001-10-04	N-aryl-1,2,4-triazolin-5-one
IT1272894B (it)	1997-07-01	Erogatore per autorestiratori subacquei.
IT1301910B1 (it)	2000-07-07	Macchina per termoformatura.
FR2718531B1 (fr)	1997-01-17	Plaque de microtitrage.
IT1297636B1 (it)	1999-12-20	Macchina per la lavorazione di legno.
IT1273427B (it)	1997-07-08	Dispositivo di giunzione di pannelli, ad avvitamento
TR199600889A2 (tr)	1997-05-21	Fungisit bilesikler (B).
SI0843661T1 (en)	2002-06-30	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanolmethanesulfonate trihydrate
IT1269022B (it)	1997-03-18	Tappo per operazioni di sfecciatura.
IT239134Y1 (it)	2001-02-19	Dispositivo aspirante, particolarmente per w.c.
ES1029982Y (es)	1996-01-01	Envase prismatico perfeccionado.
IT1274839B (it)	1997-07-25	Apparecchiatura perfezionata per trattamenti di dialisi.
ITBO950167A0 (it)	1995-04-14	Composti a struttura 3,4 di idro-2-iodometil-2,5,7,8-tetrametil-2h-1 benzopiranica.
ITBO940414A0 (it)	1994-09-21	Manipolo endoorale per riprese di video-immagini.
ITBO970490A0 (it)	1997-08-04	Dispositivo per il confezionamento di articoli vari.
ITTO940244V0 (it)	1994-12-13	Confezione di vol-au-vent.
IT235626Y1 (it)	2000-07-12	Macchina per i trattamenti di biotermolisi.
IT234664Y1 (it)	2000-03-13	Pinza per elevatori-sollevatori.
IT234100Y1 (it)	2000-02-23	Macchina per vibromassaggi.
ES1030669Y (es)	1996-03-01	Cabeza de tornillo.
IT1285084B1 (it)	1998-06-03	Macchina fotografica per stereoscopia.
IT232913Y1 (it)	2000-01-21	architettura per macchine calibratrici-levigatrici.
ES1031128Y (es)	1996-05-01	Maquina recreativo-deportiva perfeccionada.

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