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NO981071L - Hydrolyse-fremmende taksan-hydrofobiske derivater - Google Patents

Hydrolyse-fremmende taksan-hydrofobiske derivater

Info

Publication number
NO981071L
NO981071L NO981071A NO981071A NO981071L NO 981071 L NO981071 L NO 981071L NO 981071 A NO981071 A NO 981071A NO 981071 A NO981071 A NO 981071A NO 981071 L NO981071 L NO 981071L
Authority
NO
Norway
Prior art keywords
taxane
hydrolysis
promoting
hydrocarbon
hydrophobic derivatives
Prior art date
Application number
NO981071A
Other languages
English (en)
Other versions
NO981071D0 (no
NO319521B1 (no
Inventor
Eric Mayhew
Shaukat Ali
Andrew Stuart Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of NO981071D0 publication Critical patent/NO981071D0/no
Publication of NO981071L publication Critical patent/NO981071L/no
Publication of NO319521B1 publication Critical patent/NO319521B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
NO19981071A 1995-09-12 1998-03-11 Hydrolysefremmende taksan-hydrofobiske derivater, sammensetninger og anvendelse derav. NO319521B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting taxane hydrophobic derivatives

Publications (3)

Publication Number Publication Date
NO981071D0 NO981071D0 (no) 1998-03-11
NO981071L true NO981071L (no) 1998-05-12
NO319521B1 NO319521B1 (no) 2005-08-22

Family

ID=21706522

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19981071A NO319521B1 (no) 1995-09-12 1998-03-11 Hydrolysefremmende taksan-hydrofobiske derivater, sammensetninger og anvendelse derav.

Country Status (21)

Country Link
US (1) US5703117A (no)
EP (1) EP0902783B1 (no)
JP (1) JP4192208B2 (no)
KR (1) KR100401220B1 (no)
CN (1) CN1100770C (no)
AT (2) ATE309235T1 (no)
CA (1) CA2231750C (no)
CZ (1) CZ288562B6 (no)
DE (2) DE69635428T2 (no)
DK (2) DK1229030T3 (no)
ES (2) ES2252347T3 (no)
HU (1) HU226325B1 (no)
IL (1) IL123595A (no)
MX (1) MX9801871A (no)
NO (1) NO319521B1 (no)
NZ (1) NZ318300A (no)
PL (1) PL187738B1 (no)
PT (1) PT902783E (no)
SK (1) SK283199B6 (no)
TR (1) TR199800443T1 (no)
WO (1) WO1997010234A1 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
JP2001522799A (ja) 1997-11-10 2001-11-20 メモリアル スローン−ケタリング キャンサー センター 三酸化ヒ素製剤の製造方法および三酸化ヒ素またはメラルソプロールを使用する癌の治療方法
BR9911031A (pt) * 1998-05-20 2002-01-29 Liposome Co Inc Novas formulações em partìculas
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
EP1143968B9 (en) * 1999-01-12 2004-08-04 Quanam Medical Corporation Composition and methods for administration of water-insoluble paclitaxel derivatives
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
EP1301500B1 (en) 2000-06-22 2007-11-21 Nitromed, Inc. Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
EP1304103B1 (en) * 2001-10-22 2008-12-31 Viroblock SA New non-phospholipid lipid vesicles (npLV) and their use in cosmetic, therapeutic and prophylactic applications
CA2466851C (en) * 2001-11-26 2012-09-11 Supergen, Inc. Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
DE60335279D1 (de) * 2002-06-26 2011-01-20 Medigene Ag Neues verfahren zur stabilisierung von diagnostischen und therapeutischen verbindungen in einem kationischen trägersystem
BRPI0407096A (pt) 2003-02-03 2006-01-24 Neopharm Inc Taxano encapsulado em lipossomo estável, estéril e filtrável e outros fármacos antineoplásicos
EP3345632A1 (en) * 2005-02-18 2018-07-11 Abraxis BioScience, LLC Drugs with improved hydrophobicity for incorporation in medical devices
JP2008535927A (ja) * 2005-04-12 2008-09-04 ウィスコンシン アルムニ リサーチ ファンデイション ポリマー及びパッセンジャー薬のミセル組成物
WO2009126401A1 (en) * 2008-04-10 2009-10-15 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
RU2010145529A (ru) * 2008-04-10 2012-05-20 АБРАКСИС БАЙОСАЙЕНС ЭлЭлСи (US) Композиции гидрофобных производных таксана и их применение
US8236329B2 (en) 2009-09-25 2012-08-07 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
JP3492690B2 (ja) * 1992-12-23 2004-02-03 ブリストル‐マイアーズ スクイブ カンパニー 新規な側鎖をもつタキサン類およびその中間体類
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State C10 taxane derivatives and pharmaceutical compositions containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
EP0902783B1 (en) 2002-04-17
AU706290B2 (en) 1999-06-10
SK283199B6 (sk) 2003-03-04
NO981071D0 (no) 1998-03-11
EP0902783A4 (no) 1999-03-24
US5703117A (en) 1997-12-30
WO1997010234A1 (en) 1997-03-20
KR19990044409A (ko) 1999-06-25
HU226325B1 (en) 2008-08-28
HUP9901433A2 (hu) 2001-04-28
DK1229030T3 (da) 2006-02-13
PL325477A1 (en) 1998-07-20
IL123595A0 (en) 1998-10-30
DE69635428D1 (de) 2005-12-15
JP2001519755A (ja) 2001-10-23
ATE216377T1 (de) 2002-05-15
HUP9901433A3 (en) 2001-05-28
TR199800443T1 (xx) 1998-06-22
CA2231750A1 (en) 1997-03-20
PT902783E (pt) 2002-09-30
EP0902783A1 (en) 1999-03-24
HK1016169A1 (en) 1999-10-29
DK0902783T3 (da) 2002-07-22
AU6975696A (en) 1997-04-01
CA2231750C (en) 2006-07-11
NZ318300A (en) 1999-08-30
PL187738B1 (pl) 2004-09-30
ES2252347T3 (es) 2006-05-16
CN1202166A (zh) 1998-12-16
CN1100770C (zh) 2003-02-05
NO319521B1 (no) 2005-08-22
DE69620802D1 (de) 2002-05-23
JP4192208B2 (ja) 2008-12-10
CZ288562B6 (cs) 2001-07-11
KR100401220B1 (ko) 2004-03-20
DE69635428T2 (de) 2006-06-14
ES2179208T3 (es) 2003-01-16
SK33498A3 (en) 1998-08-05
IL123595A (en) 2000-10-31
CZ71198A3 (cs) 1998-07-15
DE69620802T2 (de) 2002-10-10
MX9801871A (es) 1998-05-31
ATE309235T1 (de) 2005-11-15

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