PT902783E - Derivados hidrofobicos do taxano que promovem hidrolise - Google Patents

Derivados hidrofobicos do taxano que promovem hidrolise

Info

Publication number: PT902783E
Authority: PT; Portugal
Prior art keywords: taxane; hydrocarbon; taxano; hydrolysis; hpg
Prior art date: 1995-09-12

Application number

PT96930847T

Other languages

English (en)

Inventor

Eric Mayhew

Shaukat Ali

Andrew S Janoff

Original Assignee

Elan Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-12

Filing date

1996-09-12

Publication date

2002-09-30

1996-09-12 Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc

2002-09-30 Publication of PT902783E publication Critical patent/PT902783E/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicinal Preparation (AREA)

PT96930847T 1995-09-12 1996-09-12 Derivados hidrofobicos do taxano que promovem hidrolise PT902783E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US357595P	1995-09-12	1995-09-12

Publications (1)

Publication Number	Publication Date
PT902783E true PT902783E (pt)	2002-09-30

Family

ID=21706522

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96930847T PT902783E (pt)	1995-09-12	1996-09-12	Derivados hidrofobicos do taxano que promovem hidrolise

Country Status (21)

Country	Link
US (1)	US5703117A (pt)
EP (1)	EP0902783B1 (pt)
JP (1)	JP4192208B2 (pt)
KR (1)	KR100401220B1 (pt)
CN (1)	CN1100770C (pt)
AT (2)	ATE216377T1 (pt)
CA (1)	CA2231750C (pt)
CZ (1)	CZ288562B6 (pt)
DE (2)	DE69620802T2 (pt)
DK (2)	DK1229030T3 (pt)
ES (2)	ES2252347T3 (pt)
HU (1)	HU226325B1 (pt)
IL (1)	IL123595A (pt)
MX (1)	MX9801871A (pt)
NO (1)	NO319521B1 (pt)
NZ (1)	NZ318300A (pt)
PL (1)	PL187738B1 (pt)
PT (1)	PT902783E (pt)
SK (1)	SK283199B6 (pt)
TR (1)	TR199800443T1 (pt)
WO (1)	WO1997010234A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6107332A (en) *	1995-09-12	2000-08-22	The Liposome Company, Inc.	Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) *	1996-02-16	2003-12-23	Elan Pharmaceuticals, Inc.	D and L etherlipid stereoisomers and liposomes
US5912264A (en) *	1997-03-03	1999-06-15	Bristol-Myers Squibb Company	6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en)	1997-06-27	2014-10-07	Abraxis Bioscience, Llc	Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
IL136051A0 (en) *	1997-11-10	2001-05-20	Sloan Kettering Inst Cancer	Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
JP2002535242A (ja) *	1998-05-20	2002-10-22	ザリポソームカンパニー、インコーポレーテッド	新規な粒子状剤型
US6146659A (en) *	1998-07-01	2000-11-14	Neopharm, Inc.	Method of administering liposomal encapsulated taxane
US7314637B1 (en)	1999-06-29	2008-01-01	Neopharm, Inc.	Method of administering liposomal encapsulated taxane
AU775875B2 (en) *	1999-01-12	2004-08-19	Quanam Medical Corporation	Composition and methods for administration of water-insoluble paclitaxel derivatives
AU775373B2 (en)	1999-10-01	2004-07-29	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CA2410632A1 (en)	2000-06-22	2001-12-27	David S. Garvey	Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) *	2000-08-29	2003-08-19	Micron Technology, Inc.	Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
DE60137229D1 (de) *	2001-10-22	2009-02-12	Viroblock Sa	Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
AU2002351169B2 (en) *	2001-11-26	2007-09-20	Intas Pharmaceuticals Limited	Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
CA2492080A1 (en) *	2002-06-26	2004-01-08	Medigene Oncology Gmbh	Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system
WO2004069224A2 (en)	2003-02-03	2004-08-19	Neopharm, Inc.	Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
CN105688289A (zh) *	2005-02-18	2016-06-22	阿布拉西斯生物科学公司	用于整合入医疗装置的疏水性改善的药物
AU2006235538A1 (en)	2005-04-12	2006-10-19	Wisconsin Alumni Research Foundation	Micelle composition of polymer and passenger drug
RU2010145529A (ru) *	2008-04-10	2012-05-20	АБРАКСИС БАЙОСАЙЕНС ЭлЭлСи (US)	Композиции гидрофобных производных таксана и их применение
MX2010011165A (es) *	2008-04-10	2011-02-22	Abraxis Bioscience Llc	Composiciones de derivados de taxano hidrofobos y sus usos.
EP2480207B1 (en)	2009-09-25	2016-11-09	Wisconsin Alumni Research Foundation	Micelle encapsulation of therapeutic agents
CN105503844A (zh) *	2015-12-11	2016-04-20	上海大学	C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) *	2019-12-03	2022-01-28	沈阳药科大学	卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5059699A (en) *	1990-08-28	1991-10-22	Virginia Tech Intellectual Properties, Inc.	Water soluble derivatives of taxol
US5278324A (en) *	1990-08-28	1994-01-11	Virginia Tech Intellectual Properties, Inc.	Water soluble derivatives of taxol
CA2119261C (en) *	1992-12-23	2006-01-31	Michael A. Poss	Novel sidechain-bearing taxanes and intermediates thereof
IL108316A (en) *	1993-01-15	2006-10-31	Univ Florida State	C10 taxane derivatives and pharmaceutical compositions containing them
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives

1996
- 1996-09-12 SK SK334-98A patent/SK283199B6/sk unknown
- 1996-09-12 DK DK02008590T patent/DK1229030T3/da active
- 1996-09-12 KR KR10-1998-0701653A patent/KR100401220B1/ko not_active Expired - Fee Related
- 1996-09-12 DK DK96930847T patent/DK0902783T3/da active
- 1996-09-12 ES ES02008590T patent/ES2252347T3/es not_active Expired - Lifetime
- 1996-09-12 AT AT96930847T patent/ATE216377T1/de not_active IP Right Cessation
- 1996-09-12 ES ES96930847T patent/ES2179208T3/es not_active Expired - Lifetime
- 1996-09-12 NZ NZ318300A patent/NZ318300A/xx unknown
- 1996-09-12 TR TR1998/00443T patent/TR199800443T1/xx unknown
- 1996-09-12 PL PL96325477A patent/PL187738B1/pl not_active IP Right Cessation
- 1996-09-12 CA CA002231750A patent/CA2231750C/en not_active Expired - Fee Related
- 1996-09-12 HU HU9901433A patent/HU226325B1/hu unknown
- 1996-09-12 IL IL12359596A patent/IL123595A/xx not_active IP Right Cessation
- 1996-09-12 DE DE69620802T patent/DE69620802T2/de not_active Expired - Fee Related
- 1996-09-12 WO PCT/US1996/014631 patent/WO1997010234A1/en not_active Ceased
- 1996-09-12 JP JP51210297A patent/JP4192208B2/ja not_active Expired - Fee Related
- 1996-09-12 US US08/712,684 patent/US5703117A/en not_active Expired - Fee Related
- 1996-09-12 EP EP96930847A patent/EP0902783B1/en not_active Expired - Lifetime
- 1996-09-12 CN CN96198237A patent/CN1100770C/zh not_active Expired - Fee Related
- 1996-09-12 DE DE69635428T patent/DE69635428T2/de not_active Expired - Fee Related
- 1996-09-12 AT AT02008590T patent/ATE309235T1/de not_active IP Right Cessation
- 1996-09-12 PT PT96930847T patent/PT902783E/pt unknown
- 1996-09-12 MX MX9801871A patent/MX9801871A/es not_active IP Right Cessation
- 1996-09-12 CZ CZ1998711A patent/CZ288562B6/cs not_active IP Right Cessation
1998
- 1998-03-11 NO NO19981071A patent/NO319521B1/no unknown

Also Published As

Publication number	Publication date
PL325477A1 (en)	1998-07-20
MX9801871A (es)	1998-05-31
AU6975696A (en)	1997-04-01
ES2179208T3 (es)	2003-01-16
DK0902783T3 (da)	2002-07-22
EP0902783A1 (en)	1999-03-24
KR100401220B1 (ko)	2004-03-20
DE69635428T2 (de)	2006-06-14
ATE309235T1 (de)	2005-11-15
ATE216377T1 (de)	2002-05-15
DE69620802D1 (de)	2002-05-23
NO319521B1 (no)	2005-08-22
IL123595A0 (en)	1998-10-30
NZ318300A (en)	1999-08-30
NO981071D0 (no)	1998-03-11
DE69635428D1 (de)	2005-12-15
DK1229030T3 (da)	2006-02-13
HU226325B1 (en)	2008-08-28
CZ71198A3 (cs)	1998-07-15
TR199800443T1 (xx)	1998-06-22
HUP9901433A3 (en)	2001-05-28
US5703117A (en)	1997-12-30
HUP9901433A2 (hu)	2001-04-28
CZ288562B6 (cs)	2001-07-11
JP4192208B2 (ja)	2008-12-10
PL187738B1 (pl)	2004-09-30
AU706290B2 (en)	1999-06-10
CN1202166A (zh)	1998-12-16
CA2231750C (en)	2006-07-11
KR19990044409A (ko)	1999-06-25
JP2001519755A (ja)	2001-10-23
NO981071L (no)	1998-05-12
DE69620802T2 (de)	2002-10-10
SK33498A3 (en)	1998-08-05
CN1100770C (zh)	2003-02-05
HK1016169A1 (en)	1999-10-29
IL123595A (en)	2000-10-31
EP0902783A4 (pt)	1999-03-24
ES2252347T3 (es)	2006-05-16
WO1997010234A1 (en)	1997-03-20
SK283199B6 (sk)	2003-03-04
EP0902783B1 (en)	2002-04-17
CA2231750A1 (en)	1997-03-20

Publication	Publication Date	Title
PT902783E (pt)	2002-09-30	Derivados hidrofobicos do taxano que promovem hidrolise
DE69713526D1 (de)	2002-07-25	Lösliche prodrugs von paclitaxel
MX9603479A (es)	1997-12-31	Derivados de 4-amino de acido micofenolico con actividad inmunosupresora.
FI952248A7 (fi)	1995-05-09	Kasvainvastaisia koostumuksia, jotka sisältävät taksaanijohdannaisia
EA200000282A1 (ru)	2000-10-30	Способ введения таксана пациенту, нуждающемуся в лечении таксаном, способ лечения человека таксаном (варианты)
PT977564E (pt)	2005-08-31	Forscolina para promocao da massa corporal magra
DE69226197D1 (de)	1998-08-13	Hämoglobine als arzneimittelabgabesystem
ES2154622T1 (es)	2001-04-16	Derivados del taxano hidrofobos.
FI935394A0 (fi)	1993-12-02	Foerbaettringar i betraeffande kontrastmedel
ATE324119T1 (de)	2006-05-15	Verwendung von saccharid-konjugaten
CY1109695T1 (el)	2014-08-13	Μικροοργανισμοι αποδομησης οξαλικου ή ενζυμα αποδομησης οξαλικου για την προληψη παθησης σχετιζομενης με οξαλικο
SE8404283L (sv)	1986-03-01	Anvendning av ett specifikt tumorassocierat antigen, nemligen sialosyllaktotetraos, for diagnostiska och terapeutiska forfaranden vid cancersjukdomar
BR0105776A (pt)	2002-08-13	Tratamento de combinação para a depressão,a ansiedade e a psicose
BR0015149A (pt)	2002-10-29	Método e composições para administração de taxanos oralmente a pacientes humanos
ATE141796T1 (de)	1996-09-15	2',5'-oligoadenylat-derivate zur verwendung als heilmittel
ES2169124T3 (es)	2002-07-01	Acido 4-aminomicofenolico 6-sustituido y derivados con actividad inmunosupresora.
EP1229030A3 (en)	2002-09-25	Hydrolysis-promoting taxane hydrophobic derivates
BR0014687A (pt)	2002-11-19	Compostos de taxano pentacìclico
PT1058544E (pt)	2005-04-29	Inibicao da actividade do tnf
IT208536Z2 (it)	1988-05-28	Struttura di cannula vaginale monouso, per l'applicazione di pomate, medicamenti semidensi e simili.
UA15177C2 (uk)	1999-08-30	Засіб для лікуваhhя уражеhь слизової травhого тракту