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NO20035696D0 - Krystallinsk anti-cholinergikum, fremgangsmåte for fremstilling derav og anvendelse derav til fremstilling av et legemiddel - Google Patents

Krystallinsk anti-cholinergikum, fremgangsmåte for fremstilling derav og anvendelse derav til fremstilling av et legemiddel

Info

Publication number
NO20035696D0
NO20035696D0 NO20035696A NO20035696A NO20035696D0 NO 20035696 D0 NO20035696 D0 NO 20035696D0 NO 20035696 A NO20035696 A NO 20035696A NO 20035696 A NO20035696 A NO 20035696A NO 20035696 D0 NO20035696 D0 NO 20035696D0
Authority
NO
Norway
Prior art keywords
cholinergic
drug
manufacture
preparation
crystalline anti
Prior art date
Application number
NO20035696A
Other languages
English (en)
Other versions
NO334301B1 (no
Inventor
Ulrike Werthmann
Peter Sieger
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO20035696D0 publication Critical patent/NO20035696D0/no
Publication of NO334301B1 publication Critical patent/NO334301B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • C07D451/10Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
NO20035696A 2001-06-22 2003-12-19 Vannfritt, krystallinsk tiotropiumbromid, fremgangsmåte for fremstilling derav, legemiddel derav og anvendelse derav for fremstilling av et legemiddel for behandling av sykdommer NO334301B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10129710 2001-06-22
DE10215436 2002-04-08
PCT/EP2002/006291 WO2003000265A1 (de) 2001-06-22 2002-06-08 Kristallines anticholinergikum, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels

Publications (2)

Publication Number Publication Date
NO20035696D0 true NO20035696D0 (no) 2003-12-19
NO334301B1 NO334301B1 (no) 2014-02-03

Family

ID=26009556

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035696A NO334301B1 (no) 2001-06-22 2003-12-19 Vannfritt, krystallinsk tiotropiumbromid, fremgangsmåte for fremstilling derav, legemiddel derav og anvendelse derav for fremstilling av et legemiddel for behandling av sykdommer

Country Status (37)

Country Link
EP (1) EP1401445B1 (no)
JP (1) JP2005504015A (no)
KR (2) KR100971616B1 (no)
CN (1) CN100586948C (no)
AR (1) AR037491A1 (no)
AT (1) ATE337006T1 (no)
AU (1) AU2002345016B2 (no)
BG (1) BG66303B1 (no)
BR (1) BR0210537A (no)
CA (1) CA2450961C (no)
CO (1) CO5550423A2 (no)
CY (1) CY1105223T1 (no)
CZ (1) CZ302786B6 (no)
DE (1) DE50207943D1 (no)
DK (1) DK1401445T3 (no)
EA (1) EA005813B1 (no)
EE (1) EE05316B1 (no)
EG (1) EG24851A (no)
ES (1) ES2271280T3 (no)
HR (1) HRP20031066B1 (no)
HU (1) HUP0400333A3 (no)
IL (2) IL159238A0 (no)
ME (1) ME00412B (no)
MX (1) MXPA03011718A (no)
MY (1) MY122779A (no)
NO (1) NO334301B1 (no)
NZ (1) NZ530690A (no)
PE (2) PE20081305A1 (no)
PL (1) PL208137B1 (no)
PT (1) PT1401445E (no)
RS (1) RS50441B (no)
SA (1) SA02230255B1 (no)
SI (1) SI1401445T1 (no)
SK (1) SK287262B6 (no)
TW (2) TW200617007A (no)
UY (1) UY27342A1 (no)
WO (1) WO2003000265A1 (no)

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GB0716026D0 (en) 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
BRPI0818006B8 (pt) 2007-10-19 2021-05-25 Boehringer Ingelheim Int compostos de piperidino-di-hidrotienopirimidinas substituídas, uso dos mesmos e formulações farmacêuticas
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
EA020548B1 (ru) 2008-12-19 2014-12-30 Бёрингер Ингельхайм Интернациональ Гмбх Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл
EP2403851B1 (en) 2009-03-06 2015-06-17 Mahmut Bilgic New crystalline forms of tiotropium bromide
JP5658272B2 (ja) 2009-12-17 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ccr2の新規アンタゴニスト及びこれらの使用
ME01908B (me) 2009-12-17 2014-12-20 Boehringer Ingelheim Int Novi antagonisti ccr2 receptora i njihova primjena
KR20120125267A (ko) 2010-01-29 2012-11-14 베링거 인겔하임 인터내셔날 게엠베하 치환된 나프티리딘 및 syk 키나제 억제제로서의 이의 용도
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TR201102068A2 (tr) 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal maddeler
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JP5786257B2 (ja) 2011-06-16 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の選択的ccr2拮抗薬
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KR102431017B1 (ko) 2014-03-19 2022-08-11 베링거 인겔하임 인터내셔날 게엠베하 헤테로아릴 syk 억제제
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Also Published As

Publication number Publication date
CZ302786B6 (cs) 2011-11-09
PT1401445E (pt) 2006-10-31
AU2002345016B2 (en) 2008-04-17
KR20040018285A (ko) 2004-03-02
CA2450961C (en) 2010-03-30
BG66303B1 (bg) 2013-03-29
TW200617007A (en) 2006-06-01
HRP20031066B1 (en) 2011-10-31
SK522004A3 (en) 2004-06-08
KR101011353B1 (ko) 2011-01-28
PL208137B1 (pl) 2011-03-31
SA02230255B1 (ar) 2006-10-31
BG108440A (bg) 2004-08-31
CN100586948C (zh) 2010-02-03
PE20030130A1 (es) 2003-04-02
DK1401445T3 (da) 2006-11-27
HK1068540A1 (zh) 2005-04-29
HUP0400333A2 (hu) 2004-12-28
DE50207943D1 (de) 2006-10-05
MEP62008A (en) 2011-05-10
BR0210537A (pt) 2004-06-22
CN1520294A (zh) 2004-08-11
MY122779A (en) 2006-05-31
EP1401445A1 (de) 2004-03-31
EA200301293A1 (ru) 2004-08-26
PE20081305A1 (es) 2008-10-01
SI1401445T1 (sl) 2007-02-28
MXPA03011718A (es) 2004-12-06
RS50441B (sr) 2010-03-02
CY1105223T1 (el) 2010-03-03
YU99703A (sh) 2006-05-25
UY27342A1 (es) 2003-02-28
CA2450961A1 (en) 2003-01-03
WO2003000265A1 (de) 2003-01-03
KR100971616B1 (ko) 2010-07-22
ES2271280T3 (es) 2007-04-16
EE200400029A (et) 2004-04-15
IL159238A (en) 2010-04-15
EE05316B1 (et) 2010-08-16
HRP20031066A2 (en) 2004-04-30
NZ530690A (en) 2005-05-27
KR20090031638A (ko) 2009-03-26
CO5550423A2 (es) 2005-08-31
CZ2004120A3 (cs) 2004-05-12
TWI261589B (en) 2006-09-11
HUP0400333A3 (en) 2012-10-29
NO334301B1 (no) 2014-02-03
EP1401445B1 (de) 2006-08-23
ATE337006T1 (de) 2006-09-15
AR037491A1 (es) 2004-11-17
IL159238A0 (en) 2004-06-01
SK287262B6 (sk) 2010-04-07
PL364489A1 (en) 2004-12-13
JP2005504015A (ja) 2005-02-10
ME00412B (me) 2011-10-10
EG24851A (en) 2010-10-27
EA005813B1 (ru) 2005-06-30

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