TW200617007A - Crystalline anticholinergic and its use for preparing a pharmaceutical composition - Google Patents

Crystalline anticholinergic and its use for preparing a pharmaceutical composition

Info

Publication number: TW200617007A
Authority: TW; Taiwan
Prior art keywords: preparing; pharmaceutical composition; anticholinergic; crystalline; crystalline anticholinergic
Prior art date: 2001-06-22

Application number

TW095100968A

Other languages

English (en)

Inventor

Peter Sieger

Ulrike Werthmann

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-22

Filing date

2002-06-19

Publication date

2006-06-01

2002-06-19 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2006-06-01 Publication of TW200617007A publication Critical patent/TW200617007A/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pulmonology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

TW095100968A 2001-06-22 2002-06-19 Crystalline anticholinergic and its use for preparing a pharmaceutical composition TW200617007A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10129710		2001-06-22
DE10215436		2002-04-08

Publications (1)

Publication Number	Publication Date
TW200617007A true TW200617007A (en)	2006-06-01

Family

ID=26009556

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
TW095100968A TW200617007A (en)	2001-06-22	2002-06-19	Crystalline anticholinergic and its use for preparing a pharmaceutical composition
TW091113373A TWI261589B (en)	2001-06-22	2002-06-19	Crystalline anticholinergic and processes for preparing it

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
TW091113373A TWI261589B (en)	2001-06-22	2002-06-19	Crystalline anticholinergic and processes for preparing it

Country Status (37)

Country	Link
EP (1)	EP1401445B1 (zh)
JP (1)	JP2005504015A (zh)
KR (2)	KR101011353B1 (zh)
CN (1)	CN100586948C (zh)
AR (1)	AR037491A1 (zh)
AT (1)	ATE337006T1 (zh)
AU (1)	AU2002345016B2 (zh)
BG (1)	BG66303B1 (zh)
BR (1)	BR0210537A (zh)
CA (1)	CA2450961C (zh)
CO (1)	CO5550423A2 (zh)
CY (1)	CY1105223T1 (zh)
CZ (1)	CZ302786B6 (zh)
DE (1)	DE50207943D1 (zh)
DK (1)	DK1401445T3 (zh)
EA (1)	EA005813B1 (zh)
EE (1)	EE05316B1 (zh)
EG (1)	EG24851A (zh)
ES (1)	ES2271280T3 (zh)
HR (1)	HRP20031066B1 (zh)
HU (1)	HUP0400333A3 (zh)
IL (2)	IL159238A0 (zh)
ME (1)	ME00412B (zh)
MX (1)	MXPA03011718A (zh)
MY (1)	MY122779A (zh)
NO (1)	NO334301B1 (zh)
NZ (1)	NZ530690A (zh)
PE (2)	PE20081305A1 (zh)
PL (1)	PL208137B1 (zh)
PT (1)	PT1401445E (zh)
RS (1)	RS50441B (zh)
SA (1)	SA02230255B1 (zh)
SI (1)	SI1401445T1 (zh)
SK (1)	SK287262B6 (zh)
TW (2)	TW200617007A (zh)
UY (1)	UY27342A1 (zh)
WO (1)	WO2003000265A1 (zh)

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DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
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EA013157B1 (ru)	2004-04-22	2010-02-26	Бёрингер Ингельхайм Интернациональ Гмбх	Содержащие бензоксазины лекарственные комбинации для лечения заболеваний дыхательных путей
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
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CN101208316B (zh)	2005-08-15	2012-05-09	贝林格尔·英格海姆国际有限公司	制备β-模拟物的方法
TWI396541B (zh) *	2005-10-10	2013-05-21	Boehringer Ingelheim Int	用於治療呼吸疾病之新穎藥物組合
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
US9108962B2 (en)	2005-12-19	2015-08-18	Sicor, Inc.	Forms of tiotropium bromide and processes for preparation thereof
CN102731494A (zh)	2005-12-19	2012-10-17	西科尔公司	噻托溴铵的新形式及其制备方法
CN100999521B (zh) *	2006-01-13	2010-12-08	江苏正大天晴药业股份有限公司	结晶性抗胆碱药噻托溴铵
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GB0716026D0 (en)	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
WO2009050248A1 (de)	2007-10-19	2009-04-23	Boehringer Ingelheim International Gmbh	Substituierte piperidino-dihydrothienopyrimidine
EP2093219A1 (de)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
KR101754698B1 (ko)	2008-12-19	2017-07-26	센트렉시온 테라퓨틱스 코포레이션	염증, 천식 및 ｃｏｐｄ 치료용 ｃｃｒ2 수용체 길항제로서의 사이클릭 피리미딘-4-카복스아미드
WO2010101538A2 (en)	2009-03-06	2010-09-10	Bilgic Mahmut	New crystal forms
HRP20141143T1 (hr)	2009-12-17	2015-01-02	Boehringer Ingelheim International Gmbh	Novi antagonisti receptora ccr2 i njihove uporabe
JP5658272B2 (ja)	2009-12-17	2015-01-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Ｃｃｒ２の新規アンタゴニスト及びこれらの使用
MX2012008533A (es)	2010-01-29	2012-08-31	Boehringer Ingelheim Int	Naftiridinas sustituidas y su uso como inhibidores de syk quinasa.
US8946218B2 (en)	2010-05-12	2015-02-03	Boehringer Ingelheim International Gmbh	CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
WO2011141474A1 (en)	2010-05-12	2011-11-17	Boehringer Ingelheim International Gmbh	Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
EP2571870B1 (en)	2010-05-17	2015-01-21	Boehringer Ingelheim International GmbH	Ccr2 antagonists and uses thereof
EP2576542B1 (en)	2010-05-25	2015-04-22	Boehringer Ingelheim International GmbH	Cyclic amide derivatives of pyridazine-3-carboxylic acids and their use in the treatment of pulmonary, pain, immune related and cardiovascular diseases
JP5721242B2 (ja)	2010-06-01	2015-05-20	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規ｃｃｒ２アンタゴニスト
TR201007108A2 (tr) *	2010-08-25	2012-03-21	B�Lg�� Mahmut	Yeni tiotropyum bromür kristali ve üretim yöntemi.@
JP5959537B2 (ja)	2011-01-28	2016-08-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	置換ピリジニル−ピリミジン及び医薬としてのその使用
TR201101897A2 (tr)	2011-02-28	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür içeren kristal madde
TR201111589A2 (tr) *	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür susuz kristal formu.
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WO2012171863A1 (en)	2011-06-16	2012-12-20	Boehringer Ingelheim International Gmbh	New selective ccr2 antagonists
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US20130059866A1 (en)	2011-08-24	2013-03-07	Boehringer Ingelheim International Gmbh	Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
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2002
- 2002-06-08 EP EP02743165A patent/EP1401445B1/de not_active Expired - Lifetime
- 2002-06-08 SK SK52-2004A patent/SK287262B6/sk unknown
- 2002-06-08 HU HU0400333A patent/HUP0400333A3/hu unknown
- 2002-06-08 PT PT02743165T patent/PT1401445E/pt unknown
- 2002-06-08 KR KR1020097004823A patent/KR101011353B1/ko not_active Expired - Lifetime
- 2002-06-08 RS YUP-997/03A patent/RS50441B/sr unknown
- 2002-06-08 CN CN02812303A patent/CN100586948C/zh not_active Expired - Lifetime
- 2002-06-08 SI SI200230431T patent/SI1401445T1/sl unknown
- 2002-06-08 CZ CZ20040120A patent/CZ302786B6/cs not_active IP Right Cessation
- 2002-06-08 KR KR1020037016769A patent/KR100971616B1/ko not_active Expired - Lifetime
- 2002-06-08 HR HR20031066A patent/HRP20031066B1/xx not_active IP Right Cessation
- 2002-06-08 EA EA200301293A patent/EA005813B1/ru not_active IP Right Cessation
- 2002-06-08 DE DE50207943T patent/DE50207943D1/de not_active Expired - Lifetime
- 2002-06-08 NZ NZ530690A patent/NZ530690A/en not_active IP Right Cessation
- 2002-06-08 JP JP2003506910A patent/JP2005504015A/ja active Pending
- 2002-06-08 ME MEP-2008-620A patent/ME00412B/me unknown
- 2002-06-08 EE EEP200400029A patent/EE05316B1/xx unknown
- 2002-06-08 BR BR0210537-3A patent/BR0210537A/pt not_active Application Discontinuation
- 2002-06-08 PL PL364489A patent/PL208137B1/pl unknown
- 2002-06-08 AU AU2002345016A patent/AU2002345016B2/en not_active Expired
- 2002-06-08 MX MXPA03011718A patent/MXPA03011718A/es active IP Right Grant
- 2002-06-08 AT AT02743165T patent/ATE337006T1/de active
- 2002-06-08 IL IL15923802A patent/IL159238A0/xx unknown
- 2002-06-08 ES ES02743165T patent/ES2271280T3/es not_active Expired - Lifetime
- 2002-06-08 WO PCT/EP2002/006291 patent/WO2003000265A1/de not_active Ceased
- 2002-06-08 DK DK02743165T patent/DK1401445T3/da active
- 2002-06-08 CA CA2450961A patent/CA2450961C/en not_active Expired - Fee Related
- 2002-06-19 TW TW095100968A patent/TW200617007A/zh unknown
- 2002-06-19 EG EG2002060698A patent/EG24851A/xx active
- 2002-06-19 TW TW091113373A patent/TWI261589B/zh not_active IP Right Cessation
- 2002-06-20 MY MYPI20022316A patent/MY122779A/en unknown
- 2002-06-20 UY UY27342A patent/UY27342A1/es not_active Application Discontinuation
- 2002-06-21 PE PE2007000660A patent/PE20081305A1/es not_active Application Discontinuation
- 2002-06-21 PE PE2002000538A patent/PE20030130A1/es active IP Right Grant
- 2002-06-21 AR ARP020102337A patent/AR037491A1/es not_active Application Discontinuation
- 2002-08-19 SA SA2230255A patent/SA02230255B1/ar unknown
2003
- 2003-12-08 IL IL159238A patent/IL159238A/en active IP Right Grant
- 2003-12-12 BG BG108440A patent/BG66303B1/bg unknown
- 2003-12-19 NO NO20035696A patent/NO334301B1/no not_active IP Right Cessation
2004
- 2004-01-20 CO CO04003764A patent/CO5550423A2/es not_active Application Discontinuation
2006
- 2006-09-20 CY CY20061101339T patent/CY1105223T1/el unknown

Also Published As

Publication number	Publication date
UY27342A1 (es)	2003-02-28
DK1401445T3 (da)	2006-11-27
HUP0400333A2 (hu)	2004-12-28
HRP20031066A2 (en)	2004-04-30
MEP62008A (en)	2011-05-10
JP2005504015A (ja)	2005-02-10
ES2271280T3 (es)	2007-04-16
AU2002345016B2 (en)	2008-04-17
SK287262B6 (sk)	2010-04-07
HUP0400333A3 (en)	2012-10-29
EA005813B1 (ru)	2005-06-30
TWI261589B (en)	2006-09-11
PE20081305A1 (es)	2008-10-01
PL208137B1 (pl)	2011-03-31
ME00412B (me)	2011-10-10
SK522004A3 (en)	2004-06-08
KR20040018285A (ko)	2004-03-02
ATE337006T1 (de)	2006-09-15
CN1520294A (zh)	2004-08-11
CZ2004120A3 (cs)	2004-05-12
NZ530690A (en)	2005-05-27
MY122779A (en)	2006-05-31
CN100586948C (zh)	2010-02-03
PT1401445E (pt)	2006-10-31
KR20090031638A (ko)	2009-03-26
YU99703A (sh)	2006-05-25
CY1105223T1 (el)	2010-03-03
EG24851A (en)	2010-10-27
DE50207943D1 (de)	2006-10-05
EP1401445B1 (de)	2006-08-23
PE20030130A1 (es)	2003-04-02
SI1401445T1 (sl)	2007-02-28
BG66303B1 (bg)	2013-03-29
HRP20031066B1 (en)	2011-10-31
MXPA03011718A (es)	2004-12-06
SA02230255B1 (ar)	2006-10-31
KR100971616B1 (ko)	2010-07-22
IL159238A0 (en)	2004-06-01
PL364489A1 (en)	2004-12-13
EP1401445A1 (de)	2004-03-31
WO2003000265A1 (de)	2003-01-03
NO20035696D0 (no)	2003-12-19
CA2450961A1 (en)	2003-01-03
CZ302786B6 (cs)	2011-11-09
EE200400029A (et)	2004-04-15
BR0210537A (pt)	2004-06-22
RS50441B (sr)	2010-03-02
CA2450961C (en)	2010-03-30
AR037491A1 (es)	2004-11-17
HK1068540A1 (zh)	2005-04-29
BG108440A (bg)	2004-08-31
EE05316B1 (et)	2010-08-16
CO5550423A2 (es)	2005-08-31
EA200301293A1 (ru)	2004-08-26
KR101011353B1 (ko)	2011-01-28
NO334301B1 (no)	2014-02-03
IL159238A (en)	2010-04-15

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