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NO20014966L - Fremstilling av biologisk aktive molekyler - Google Patents

Fremstilling av biologisk aktive molekyler

Info

Publication number
NO20014966L
NO20014966L NO20014966A NO20014966A NO20014966L NO 20014966 L NO20014966 L NO 20014966L NO 20014966 A NO20014966 A NO 20014966A NO 20014966 A NO20014966 A NO 20014966A NO 20014966 L NO20014966 L NO 20014966L
Authority
NO
Norway
Prior art keywords
preparation
biologically active
active molecules
molecules
biologically
Prior art date
Application number
NO20014966A
Other languages
English (en)
Other versions
NO329525B1 (no
NO20014966D0 (no
Inventor
Menachem Rubinstein
Bianling Liu
Daniela Novick
Charles Dinarello
Pierre Graber
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20014966D0 publication Critical patent/NO20014966D0/no
Publication of NO20014966L publication Critical patent/NO20014966L/no
Publication of NO329525B1 publication Critical patent/NO329525B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
NO20014966A 1999-04-13 2001-10-12 Fremgangsmate for fremstilling av et biologisk aktivt cytokin og et cDNA NO329525B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12942799A IL129427A0 (en) 1999-04-13 1999-04-13 Preparation of biologically active molecules
PCT/IL2000/000220 WO2000061768A2 (en) 1999-04-13 2000-04-13 Preparation of biologically active molecules

Publications (3)

Publication Number Publication Date
NO20014966D0 NO20014966D0 (no) 2001-10-12
NO20014966L true NO20014966L (no) 2001-12-11
NO329525B1 NO329525B1 (no) 2010-11-01

Family

ID=11072700

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014966A NO329525B1 (no) 1999-04-13 2001-10-12 Fremgangsmate for fremstilling av et biologisk aktivt cytokin og et cDNA

Country Status (23)

Country Link
US (1) US7098002B1 (no)
EP (1) EP1169460B1 (no)
JP (1) JP4822587B2 (no)
KR (1) KR100682185B1 (no)
CN (1) CN1324140C (no)
AR (1) AR023468A1 (no)
AT (1) ATE326536T1 (no)
AU (1) AU781342B2 (no)
BR (1) BR0009782A (no)
CA (1) CA2368994C (no)
DE (1) DE60028022T2 (no)
DK (1) DK1169460T3 (no)
EA (1) EA006825B1 (no)
EE (1) EE05591B1 (no)
ES (1) ES2259287T3 (no)
IL (3) IL129427A0 (no)
MX (1) MXPA01010487A (no)
NO (1) NO329525B1 (no)
PT (1) PT1169460E (no)
SI (1) SI1169460T1 (no)
UA (1) UA73940C2 (no)
WO (1) WO2000061768A2 (no)
ZA (1) ZA200108364B (no)

Families Citing this family (28)

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WO2001029232A2 (en) * 1999-10-20 2001-04-26 Scios Inc. Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage
US7273722B2 (en) 2000-11-29 2007-09-25 Allergan, Inc. Neurotoxins with enhanced target specificity
DE60208692T2 (de) 2001-03-08 2006-07-13 Ares Trading S.A. Interleukin -18 mutantenproteine, deren herstellung und verwendung
IL142246A0 (en) * 2001-03-26 2002-03-10 Applied Research Systems Method and kit for quantitation of polypeptides
AU2003210996A1 (en) 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
EP1597369B1 (en) * 2003-02-21 2007-10-03 Biotecnol S.A. Use of caspase enzymes for maturation of engineered recombinant polypeptide fusions
US7824885B2 (en) * 2003-08-06 2010-11-02 University Of Maryland, College Park Engineered proteases for affinity purification and processing of fusion proteins
MXPA06005837A (es) * 2003-11-24 2007-01-26 Novo Nordisk As Proteinas de fusion y metodos de desdoblamiento de tales proteinas.
US7381794B2 (en) 2004-03-08 2008-06-03 Zymogenetics, Inc. Dimeric fusion proteins and materials and methods for producing them
DK1926744T4 (en) * 2005-09-19 2019-01-28 Allergan Inc CLOSTRIDIUM TOXIN-ACTIVABLE CLOSTRIDIAL TOXINES
CA2649800C (en) * 2006-04-20 2016-09-20 Kringle Pharma Inc. Hgf precursor protein variant and active protein thereof
DE102007008596B4 (de) * 2007-02-15 2010-09-02 Friedrich-Schiller-Universität Jena Biologisch wirksame Moleküle auf Grundlage von PNA und siRNA, Verfahren zu deren zellspezifischen Aktivierung sowie Applikationskit zur Verabreichung
EP3492488A1 (en) 2007-08-22 2019-06-05 The Regents of The University of California Activatable binding polypeptides and methods of identification and use thereof
WO2009044988A1 (en) * 2007-10-01 2009-04-09 Korea Research Institute Of Bioscience And Biotechnology Method for large scale preparation of procaspases, which can be artificially activated, in e. coli expression system and their activation
DE102009043743B4 (de) 2009-03-13 2016-10-13 Friedrich-Schiller-Universität Jena Zellspezifisch wirksame Moleküle auf Grundlage von siRNA sowie Applikationskits zu deren Herstellung und Verwendung
WO2010081173A2 (en) 2009-01-12 2010-07-15 Cytomx Therapeutics, Llc Modified antibody compositions, methods of making and using thereof
AU2010215761B2 (en) * 2009-02-23 2017-04-06 Cytomx Therapeutics, Inc Proproteins and methods of use thereof
CN103923897B (zh) * 2013-01-11 2016-06-01 中国人民解放军军事医学科学院生物工程研究所 caspase重组酶原及其编码基因与应用
CN103388001B (zh) * 2013-07-16 2016-01-20 中国人民解放军第四军医大学 一种含凝血酶切割位点gst膜型表达载体及转染阳性细胞的方法
US10370692B2 (en) * 2013-12-20 2019-08-06 Hoffmann-La Roche Inc. Recombinant polypeptide production methods
CA2980172A1 (en) 2015-03-30 2016-10-06 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
IL302486A (en) 2015-06-24 2023-06-01 Hoffmann La Roche Antibodies against the transnephrine receptor with adapted affinity
AR106189A1 (es) 2015-10-02 2017-12-20 Hoffmann La Roche ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
JP6657392B2 (ja) 2015-10-02 2020-03-04 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 二重特異性抗ヒトｃｄ２０／ヒトトランスフェリン受容体抗体及び使用方法
RU2018138975A (ru) 2016-04-06 2020-05-12 Гринлайт Байосайенсис, Инк. Бесклеточная продукция рибонуклеиновой кислоты
SG11202003192UA (en) 2017-10-11 2020-05-28 Greenlight Biosciences Inc Methods and compositions for nucleoside triphosphate and ribonucleic acid production
KR20200080749A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 N-말단의 메티오닌이 절단된 목적 단백질 발현용 유전자 발현 카세트 및 이를 이용하여 n-말단의 메티오닌이 절단된 목적 단백질을 생산하는 방법
US20230000913A1 (en) * 2019-08-13 2023-01-05 King's College London Immunoresponsive cells armoured with spatiotemporally restricted activity of cytokines of the il-1 superfamily

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824297A (en) * 1990-06-25 1998-10-20 Oncogene Science, Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
CA2084992A1 (en) * 1990-06-25 1991-12-26 Osi Pharmaceuticals, Inc. Tissue-derived tumor growth inhibitors, methods for preparation and uses thereof
DE69229252T2 (de) * 1991-08-16 1999-12-16 Merck & Co., Inc. DNS, welche das Interleukin-1B-Vorläufer-Converting-Enzym kodiert
US5476777A (en) * 1991-12-31 1995-12-19 Zymogenetics, Inc. Methods for producing thrombin
JPH06125784A (ja) * 1992-01-17 1994-05-10 Takeda Chem Ind Ltd モノクローナル抗体，ハイブリドーマ，その製造法および用途
US6303369B1 (en) * 1993-09-30 2001-10-16 Carl Spana Protein expression system
CA2238885A1 (en) 1995-12-29 1997-07-10 Incyte Pharmaceuticals, Inc. Nucleic acids encoding interferon gamma inducing factor-2
JP4059941B2 (ja) * 1996-08-26 2008-03-12 社団法人芝蘭会 Ｒｈｏ標的タンパク質ｐ１４０ｍＤｉａ
AT405516B (de) 1997-02-27 1999-09-27 Immuno Ag Faktor x-analoge mit modifizierter proteasespaltstelle
JPH10327872A (ja) * 1997-05-30 1998-12-15 Otsuka Pharmaceut Co Ltd Ｂｃｌ−２相互作用蛋白遺伝子ｂｉｓ
EP2184358A3 (en) * 1997-08-07 2010-07-21 Toray Industries, Inc. Canine interleukin 18 and remedies for canine immunological diseases

Also Published As

Publication number Publication date
ES2259287T3 (es) 2006-10-01
NO329525B1 (no) 2010-11-01
JP2002541813A (ja) 2002-12-10
CN1353761A (zh) 2002-06-12
AR023468A1 (es) 2002-09-04
PT1169460E (pt) 2006-07-31
AU3985100A (en) 2000-11-14
AU781342B2 (en) 2005-05-19
KR20020007365A (ko) 2002-01-26
IL145842A (en) 2008-06-05
WO2000061768A2 (en) 2000-10-19
EA006825B1 (ru) 2006-04-28
EE200100530A (et) 2002-12-16
KR100682185B1 (ko) 2007-02-12
WO2000061768A3 (en) 2001-02-08
DK1169460T3 (da) 2006-09-18
EP1169460B1 (en) 2006-05-17
IL145842A0 (en) 2002-07-25
JP4822587B2 (ja) 2011-11-24
CA2368994A1 (en) 2000-10-19
EA200101078A1 (ru) 2002-04-25
DE60028022D1 (de) 2006-06-22
HK1044351A1 (en) 2002-10-18
CA2368994C (en) 2010-03-09
ATE326536T1 (de) 2006-06-15
ZA200108364B (en) 2002-10-11
IL129427A0 (en) 2000-02-17
DE60028022T2 (de) 2006-09-28
BR0009782A (pt) 2002-01-08
UA73940C2 (uk) 2005-10-17
MXPA01010487A (es) 2002-05-06
NO20014966D0 (no) 2001-10-12
SI1169460T1 (sl) 2006-08-31
US7098002B1 (en) 2006-08-29
CN1324140C (zh) 2007-07-04
EP1169460A2 (en) 2002-01-09
EE05591B1 (et) 2012-10-15

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