MEP24408A - Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, the preparation thereof and the application of same in therapeutics - Google Patents

Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, the preparation thereof and the application of same in therapeutics

Info

Publication number: MEP24408A
Authority: ME; Montenegro
Prior art keywords: group; azabicyclo; pyridin; therapeutics; octane
Prior art date: 2002-01-07

Application number

MEP-244/08A

Other languages

Bosnian (bs)

English (en)

Croatian (hr)

Inventor

Frederic Galli

Odile Leclerc

Alistair Lochead

Alain Nedelec

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-07

Filing date

2003-01-03

Publication date

2010-10-10

2003-01-03 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2010-10-10 Publication of MEP24408A publication Critical patent/MEP24408A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Psychiatry (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MEP-244/08A 2002-01-07 2003-01-03 Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, the preparation thereof and the application of same in therapeutics MEP24408A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0200109A FR2834511B1 (fr)	2002-01-07	2002-01-07	Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique
PCT/FR2003/000004 WO2003057697A1 (fr)	2002-01-07	2003-01-03	Derives de 5-(pyridin-3-yl)-1-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
MEP24408A true MEP24408A (en)	2010-10-10

Family

ID=8871176

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
MEP-244/08A MEP24408A (en)	2002-01-07	2003-01-03	Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, the preparation thereof and the application of same in therapeutics
MEP-2008-244A ME00213B (me)	2002-01-07	2003-01-03	Derivati 5-(piridin-3-il)-1-azabiciklo (3.2.1.) oktana, njihova priprema i terapeutska primjena

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
MEP-2008-244A ME00213B (me)	2002-01-07	2003-01-03	Derivati 5-(piridin-3-il)-1-azabiciklo (3.2.1.) oktana, njihova priprema i terapeutska primjena

Country Status (35)

Country	Link
US (2)	US7223750B2 (xx)
EP (1)	EP1465893B1 (xx)
JP (1)	JP4402957B2 (xx)
KR (1)	KR100977332B1 (xx)
CN (2)	CN1911928A (xx)
AR (2)	AR038098A1 (xx)
AT (1)	ATE355290T1 (xx)
AU (1)	AU2003216777B2 (xx)
BR (1)	BR0306707A (xx)
CA (1)	CA2471628C (xx)
CO (1)	CO5590914A2 (xx)
CY (1)	CY1106580T1 (xx)
DE (1)	DE60312123T2 (xx)
DK (1)	DK1465893T3 (xx)
EA (1)	EA007793B1 (xx)
EC (1)	ECSP045176A (xx)
ES (1)	ES2281631T3 (xx)
FR (1)	FR2834511B1 (xx)
HR (1)	HRP20040617B1 (xx)
IL (2)	IL162524A0 (xx)
IS (1)	IS2470B (xx)
MA (1)	MA27165A1 (xx)
ME (2)	MEP24408A (xx)
MX (1)	MXPA04006630A (xx)
NO (1)	NO329309B1 (xx)
NZ (1)	NZ533793A (xx)
PL (1)	PL216665B1 (xx)
PT (1)	PT1465893E (xx)
RS (1)	RS50921B (xx)
SI (1)	SI1465893T1 (xx)
TN (1)	TNSN04120A1 (xx)
TW (1)	TWI336703B (xx)
UA (1)	UA77229C2 (xx)
WO (1)	WO2003057697A1 (xx)
ZA (1)	ZA200405002B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9902007D0 (en) *	1999-01-30	1999-03-17	Thomas Carpentry Services Limi	Improvements relating to door frames
FR2834511B1 (fr) *	2002-01-07	2004-02-13	Sanofi Synthelabo	Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique
FR2889701B1 (fr) *	2005-08-12	2007-10-05	Sanofi Aventis Sa	Derives de 5-pyridinyl-1-azabicyclo[3.2.1]octane, leur preparation en therapeutique.
FR2889847B1 (fr) *	2005-08-18	2007-10-05	Sanofi Aventis Sa	Derives de 5-pyridazinyl-1-azabicyclo[3.2.1]octave, leur preparation en therapeutique.
FR2912404B1 (fr) *	2007-02-09	2009-04-10	Sanofi Aventis Sa	Derives d'azabicycloalkane,leur preparation et leur application en therapeutique.
KR101928505B1 (ko)	2011-01-28	2018-12-12	에스케이바이오팜 주식회사	피리돈 유도체 및 이를 포함하는 약학적 조성물
KR101925971B1 (ko)	2011-01-28	2018-12-06	에스케이바이오팜 주식회사	피리돈 유도체 및 이를 포함하는 약학적 조성물
EP3704117A1 (en)	2017-11-03	2020-09-09	Alcon Inc.	Azabicyclo and diazepine derivatives for treating ocular disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5817679A (en) *	1993-04-01	1998-10-06	University Of Virginia	7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands
WO1995003306A1 (en)	1993-07-22	1995-02-02	E.I. Du Pont De Nemours And Company	Arthropodicidal azacyclic heterocycles
FR2786770B1 (fr) *	1998-12-04	2001-01-19	Synthelabo	Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
FR2786769B1 (fr) *	1998-12-04	2002-10-25	Synthelabo	Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique
FR2834511B1 (fr) *	2002-01-07	2004-02-13	Sanofi Synthelabo	Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique

2002
- 2002-01-07 FR FR0200109A patent/FR2834511B1/fr not_active Expired - Fee Related
- 2002-12-31 TW TW091138055A patent/TWI336703B/zh not_active IP Right Cessation
2003
- 2003-01-03 AR ARP030100009A patent/AR038098A1/es not_active Application Discontinuation
- 2003-01-03 DE DE60312123T patent/DE60312123T2/de not_active Expired - Lifetime
- 2003-01-03 CN CNA2006101091747A patent/CN1911928A/zh active Pending
- 2003-01-03 US US10/500,015 patent/US7223750B2/en not_active Expired - Lifetime
- 2003-01-03 ES ES03712202T patent/ES2281631T3/es not_active Expired - Lifetime
- 2003-01-03 KR KR1020047010566A patent/KR100977332B1/ko not_active Expired - Fee Related
- 2003-01-03 ME MEP-244/08A patent/MEP24408A/xx unknown
- 2003-01-03 BR BR0306707-6A patent/BR0306707A/pt not_active Application Discontinuation
- 2003-01-03 EP EP03712202A patent/EP1465893B1/fr not_active Expired - Lifetime
- 2003-01-03 DK DK03712202T patent/DK1465893T3/da active
- 2003-01-03 HR HRP20040617AA patent/HRP20040617B1/hr not_active IP Right Cessation
- 2003-01-03 NZ NZ533793A patent/NZ533793A/en not_active IP Right Cessation
- 2003-01-03 WO PCT/FR2003/000004 patent/WO2003057697A1/fr not_active Ceased
- 2003-01-03 ME MEP-2008-244A patent/ME00213B/me unknown
- 2003-01-03 PT PT03712202T patent/PT1465893E/pt unknown
- 2003-01-03 JP JP2003558012A patent/JP4402957B2/ja not_active Expired - Fee Related
- 2003-01-03 PL PL370065A patent/PL216665B1/pl unknown
- 2003-01-03 AT AT03712202T patent/ATE355290T1/de active
- 2003-01-03 AU AU2003216777A patent/AU2003216777B2/en not_active Ceased
- 2003-01-03 SI SI200330774T patent/SI1465893T1/sl unknown
- 2003-01-03 CN CNB038019876A patent/CN1276921C/zh not_active Expired - Fee Related
- 2003-01-03 IL IL16252403A patent/IL162524A0/xx unknown
- 2003-01-03 RS YUP-599/04A patent/RS50921B/sr unknown
- 2003-01-03 EA EA200400770A patent/EA007793B1/ru not_active IP Right Cessation
- 2003-01-03 MX MXPA04006630A patent/MXPA04006630A/es active IP Right Grant
- 2003-01-03 CA CA2471628A patent/CA2471628C/en not_active Expired - Fee Related
- 2003-03-01 UA UA20040605056A patent/UA77229C2/uk unknown
2004
- 2004-06-14 IL IL162524A patent/IL162524A/en not_active IP Right Cessation
- 2004-06-16 IS IS7322A patent/IS2470B/is unknown
- 2004-06-24 ZA ZA200405002A patent/ZA200405002B/en unknown
- 2004-06-29 EC EC2004005176A patent/ECSP045176A/es unknown
- 2004-06-30 TN TNP2004000120A patent/TNSN04120A1/fr unknown
- 2004-07-01 CO CO04062934A patent/CO5590914A2/es active IP Right Grant
- 2004-07-01 MA MA27759A patent/MA27165A1/fr unknown
- 2004-07-05 NO NO20042846A patent/NO329309B1/no not_active IP Right Cessation
2007
- 2007-04-05 US US11/696,993 patent/US7585974B2/en not_active Expired - Fee Related
- 2007-05-10 CY CY20071100641T patent/CY1106580T1/el unknown
2012
- 2012-05-28 AR ARP120101864A patent/AR086573A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
US7223750B2 (en)	2007-05-29
DE60312123T2 (de)	2007-09-13
ZA200405002B (en)	2006-05-31
BR0306707A (pt)	2005-02-09
KR100977332B1 (ko)	2010-08-20
IL162524A0 (en)	2005-11-20
KR20040077705A (ko)	2004-09-06
US20050020568A1 (en)	2005-01-27
FR2834511B1 (fr)	2004-02-13
US20070185137A1 (en)	2007-08-09
AR086573A2 (es)	2014-01-08
MXPA04006630A (es)	2004-11-10
TNSN04120A1 (fr)	2006-06-01
FR2834511A1 (fr)	2003-07-11
NZ533793A (en)	2007-01-26
HRP20040617A2 (en)	2004-10-31
MA27165A1 (fr)	2005-01-03
CA2471628A1 (en)	2003-07-17
UA77229C2 (uk)	2006-11-15
RS59904A (sr)	2006-10-27
DK1465893T3 (da)	2007-06-04
IS2470B (is)	2008-12-15
IS7322A (is)	2004-06-16
RS50921B (sr)	2010-08-31
DE60312123D1 (de)	2007-04-12
NO329309B1 (no)	2010-09-27
CO5590914A2 (es)	2005-12-30
EP1465893A1 (fr)	2004-10-13
JP4402957B2 (ja)	2010-01-20
ECSP045176A (es)	2004-08-27
EA007793B1 (ru)	2007-02-27
ATE355290T1 (de)	2006-03-15
EA200400770A1 (ru)	2004-12-30
HRP20040617B1 (hr)	2012-10-31
JP2005514422A (ja)	2005-05-19
SI1465893T1 (sl)	2007-08-31
PT1465893E (pt)	2007-05-31
ES2281631T3 (es)	2007-10-01
IL162524A (en)	2010-05-17
AU2003216777B2 (en)	2008-10-02
AR038098A1 (es)	2004-12-29
HK1066547A1 (en)	2005-03-24
CN1911928A (zh)	2007-02-14
TWI336703B (en)	2011-02-01
CY1106580T1 (el)	2012-01-25
CN1612876A (zh)	2005-05-04
PL216665B1 (pl)	2014-04-30
EP1465893B1 (fr)	2007-02-28
CN1276921C (zh)	2006-09-27
AU2003216777A1 (en)	2003-07-24
US7585974B2 (en)	2009-09-08
CA2471628C (en)	2011-03-22
TW200305413A (en)	2003-11-01
WO2003057697A1 (fr)	2003-07-17
PL370065A1 (en)	2005-05-16
ME00213B (me)	2011-02-10
NO20042846L (no)	2004-09-21

Publication	Publication Date	Title
DK7280A (da)	1980-07-09	Fremgangsmaade til fremstilling af (piperidinylalkyl) quinazolin-derivater
NO983970D0 (no)	1998-08-28	Tricykliske forbindelser, deres fremstilling og anvendelse
BR0014133A (pt)	2002-06-11	Uso de um composto, composto, métodos de preparação de um composto, e para inibir aurora 2 quinase em um animal de sangue quente, e, composição farmacêutica
BR122017028096B8 (pt)	2021-05-25	composto, composição farmacêutica, e, uso do composto
MEP24208A (en)	2010-06-10	Derivatives of dioxane-2-alkyl carbamates, preparation method thereof and application of same in therapeutics
ATE503746T1 (de)	2011-04-15	Neue imidazolidinderivate
MEP24408A (en)	2010-10-10	Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, the preparation thereof and the application of same in therapeutics
WO2000063182A3 (de)	2001-10-11	2,4-diamino-pyrimidin-derivate und ihre verwendung als mikrobizide und heribizide
EP1854789A4 (en)	2009-06-17	QUINAZOLINE DERIVATIVE HAVING TYROSINE KINASE INHIBITORY ACTIVITY
MXPA02012411A (es)	2003-04-25	Piridin-2-il-aminoalquilcarbonilglicil-beta-alanina y derivados del mismo.
DK0806413T3 (da)	2002-01-28	2-substituerede viatmin D3-derivater
SE0101766D0 (sv)	2001-05-18	Novel compounds
DK1219621T3 (da)	2004-02-02	Azaindolizinonderivater og cerebral funktionsforbedrende midler indeholdende disse som den aktive bestanddel
MX2007004482A (es)	2007-06-13	Derivados de piridina y la preparacion y el uso terapeutico de los mismos.
TW200942539A (en)	2009-10-16	N-phenylimidazo[1,2-α]pyridine-2-carboxamide derivatives, their preparation and their therapeutic application
NO20061343L (no)	2006-03-24	Imidazo[4,5-b]pyridinderivater som induserbare NO-syntaseinhibitorer
FR2838124B1 (fr)	2004-05-28	Derives de 3-heteroaryl-3,5-dihydro-4-oxo-4h-pyridazino [4,5-b]indole-1-acetamide, leur preparation et leur application en therapeutique
WO2007057571A3 (fr)	2007-07-12	Derives de 3-acylindole, leur preparation et leur application en therapeutique comme modulateurs pour les recepteurs cb2
TW200942538A (en)	2009-10-16	2-benzoylimidazo[1,2-a]pyridine derivatives, preparation thereof and therapeutic use thereof
WO2001064671A3 (fr)	2002-03-14	Derives d'haloimidazole et leur utilisation en tant qu'antagonistes des recepteurs muscariniques m3 et serotoniques 5-ht4
WO2001034576A3 (en)	2001-11-29	Use of pyrimidinone derivatives for controlling undesired microorganisms
TH103345A (th)	2010-08-25	อนุพันธ์ 3-ไซยาโน-ควิโนลีนที่มีกิจกรรมต้านการงอกขยาย