ZA200201408B - Use of docetaxel for treating hepatocellular carcinoma. - Google Patents

Use of docetaxel for treating hepatocellular carcinoma.

Info

Publication number: ZA200201408B
Authority: ZA; South Africa
Prior art keywords: docetaxel; hepatocellular carcinoma; treating hepatocellular; treating; mum
Prior art date: 1999-08-31

Application number

ZA200201408A

Other languages

English (en)

Inventor

Chin-Wen Chi

Heng-Liang Lin

Tsung-Yun Liu

Wing-Yiu Lui

Gar-Yang Chau

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-31

Filing date

2002-02-19

Publication date

2003-07-30

2002-02-19 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2003-07-30 Publication of ZA200201408B publication Critical patent/ZA200201408B/xx

Links

ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 title abstract 3
229960003668 docetaxel Drugs 0.000 title abstract 3
206010073071 hepatocellular carcinoma Diseases 0.000 title abstract 3
231100000844 hepatocellular carcinoma Toxicity 0.000 title abstract 3
229930012538 Paclitaxel Natural products 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA200201408A 1999-08-31 2002-02-19 Use of docetaxel for treating hepatocellular carcinoma. ZA200201408B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9920548.6A GB9920548D0 (en)	1999-08-31	1999-08-31	Treatment of hepatocellular carcinoma

Publications (1)

Publication Number	Publication Date
ZA200201408B true ZA200201408B (en)	2003-07-30

Family

ID=10860081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200201408A ZA200201408B (en)	1999-08-31	2002-02-19	Use of docetaxel for treating hepatocellular carcinoma.

Country Status (34)

Country	Link
US (2)	US20030158249A1 (fr)
EP (1)	EP1214061B1 (fr)
JP (1)	JP4866522B2 (fr)
KR (1)	KR100670416B1 (fr)
CN (1)	CN1174748C (fr)
AT (1)	ATE269700T1 (fr)
AU (1)	AU777583B2 (fr)
BG (1)	BG65913B1 (fr)
BR (1)	BR0013625A (fr)
CA (1)	CA2382294C (fr)
CZ (1)	CZ301378B6 (fr)
DE (1)	DE60011794T2 (fr)
DK (1)	DK1214061T3 (fr)
EA (1)	EA004804B1 (fr)
EE (1)	EE05124B1 (fr)
ES (1)	ES2218223T3 (fr)
GB (1)	GB9920548D0 (fr)
HK (1)	HK1048944B (fr)
HR (1)	HRP20020171A2 (fr)
HU (1)	HU228861B1 (fr)
IL (2)	IL147489A0 (fr)
ME (1)	ME00624B (fr)
MX (1)	MXPA02002041A (fr)
NO (1)	NO328527B1 (fr)
NZ (1)	NZ517604A (fr)
PL (1)	PL212612B1 (fr)
PT (1)	PT1214061E (fr)
RS (1)	RS50148B (fr)
SI (1)	SI1214061T1 (fr)
SK (1)	SK286378B6 (fr)
TW (1)	TW589180B (fr)
UA (1)	UA72927C2 (fr)
WO (1)	WO2001015675A2 (fr)
ZA (1)	ZA200201408B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1268619C (zh)	2003-05-08	2006-08-09	上海迪赛诺化学制药有限公司	多烯紫杉醇三水化合物的制备方法
EP1947094A3 (fr) *	2003-12-12	2009-02-18	Quiral Quimica Do Brasil	Procédé de préparation de dérivés du taxane
US7449196B2 (en) *	2004-07-09	2008-11-11	Robert Sabin	Anti tumor compositions and methods of use
AU2006284657B2 (en)	2005-08-31	2012-07-19	Abraxis Bioscience, Llc	Compositions and methods for preparation of poorly water soluble drugs with increased stability
US7771751B2 (en)	2005-08-31	2010-08-10	Abraxis Bioscience, Llc	Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
US20080081051A1 (en) *	2006-09-28	2008-04-03	Robert Sabin	Method of manufacturing anti-tumor and anti-viral compositions
CA2683712A1 (fr) *	2007-04-20	2009-01-15	Sun Pharmaceutical Industries Limited	Compositions pharmaceutiques
FR2917088B1 (fr) *	2007-06-08	2009-09-04	Aventis Pharma Sa	Dissolution directe du docetaxel dans un solvant dans le polysorbate 80
US8541360B2 (en) *	2008-11-19	2013-09-24	Ben Venue Laboratories, Inc.	Parenteral formulations comprising sugar-based esters and ethers
NZ602382A (en)	2010-03-26	2014-11-28	Abraxis Bioscience Llc	Methods of treatment of hepatocellular carcinoma
MX341082B (es) *	2010-05-03	2016-08-08	Teikoku Pharma Usa Inc	Formulaciones de pro-emulsion de taxano no acuosas y metodos para hacer y usar las mismas.
US8842114B1 (en)	2011-04-29	2014-09-23	Nvidia Corporation	System, method, and computer program product for adjusting a depth of displayed objects within a region of a display
JO3685B1 (ar) *	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US20160250177A1 (en) *	2015-02-17	2016-09-01	Mallinckrodt Llc	Modified docetaxel liposome formulations and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5543154A (en) *	1991-12-27	1996-08-06	Merck & Co., Inc.	Controlled release nifedipine delivery device
WO1994016693A1 (fr) *	1993-01-19	1994-08-04	Warner-Lambert Company	Formulation ci-981, orale, stable et son procede de preparation
US5801029A (en) *	1993-02-16	1998-09-01	Onyx Pharmaceuticals, Inc.	Cytopathic viruses for therapy and prophylaxis of neoplasia
US5436243A (en) *	1993-11-17	1995-07-25	Research Triangle Institute Duke University	Aminoanthraquinone derivatives to combat multidrug resistance
FR2718963B1 (fr) *	1994-04-25	1996-05-24	Rhone Poulenc Rorer Sa	Nouvelle composition pharmaceutique à base de taxoïdes.
FR2722191B1 (fr) *	1994-07-08	1996-08-23	Rhone Poulenc Rorer Sa	Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
US6245805B1 (en) *	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US5968972A (en)	1995-10-26	1999-10-19	Baker Norton Pharmaceuticals, Inc.	Method for increasing the oral bioactivity of pharmaceutical agents
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
NZ336381A (en) *	1996-12-30	2000-11-24	Battelle Memorial Institute	Formulation and method for treating neoplasms by inhalation
US6503893B2 (en) *	1996-12-30	2003-01-07	Bone Care International, Inc.	Method of treating hyperproliferative diseases using active vitamin D analogues
PT1023050E (pt) *	1997-06-27	2013-12-04	Abraxis Bioscience Llc	Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização
AU1146099A (en) *	1997-09-18	1999-04-05	Janssen Pharmaceutica N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents
US6576660B1 (en) *	1997-10-31	2003-06-10	Arch Development Corporation	Methods and compositions for regulation of 5-α-reductase activity
UA73092C2 (uk) *	1998-07-17	2005-06-15	Брістол-Майерс Сквібб Компані	Таблетка з ентеросолюбільним покриттям і спосіб її приготування
JP2002533404A (ja) *	1998-12-23	2002-10-08	ジー・ディー・サール・アンド・カンパニー	新生物形成の治療における組合わせ療法としてインテグリン拮抗剤及び放射線治療を使用する方法
GB9909925D0 (en) *	1999-04-29	1999-06-30	Pharmacia & Upjohn Spa	Combined preparations comprising anthracycline derivatives
KR20080007561A (ko) *	2005-12-13	2008-01-22	테바 파마슈티컬 인더스트리즈 리미티드	아토바스타틴 헤미칼슘의 결정형 및 이의 제조 방법

1999
- 1999-08-31 GB GBGB9920548.6A patent/GB9920548D0/en not_active Ceased
- 1999-09-22 TW TW088115041A patent/TW589180B/zh not_active IP Right Cessation
2000
- 2000-08-29 CZ CZ20020739A patent/CZ301378B6/cs not_active IP Right Cessation
- 2000-08-29 EE EEP200200087A patent/EE05124B1/xx not_active IP Right Cessation
- 2000-08-29 NZ NZ517604A patent/NZ517604A/en not_active IP Right Cessation
- 2000-08-29 DK DK00964144T patent/DK1214061T3/da active
- 2000-08-29 HK HK03101197.6A patent/HK1048944B/zh not_active IP Right Cessation
- 2000-08-29 PT PT00964144T patent/PT1214061E/pt unknown
- 2000-08-29 DE DE60011794T patent/DE60011794T2/de not_active Expired - Lifetime
- 2000-08-29 PL PL353198A patent/PL212612B1/pl unknown
- 2000-08-29 ES ES00964144T patent/ES2218223T3/es not_active Expired - Lifetime
- 2000-08-29 WO PCT/EP2000/008782 patent/WO2001015675A2/fr not_active Ceased
- 2000-08-29 IL IL14748900A patent/IL147489A0/xx active IP Right Grant
- 2000-08-29 JP JP2001519889A patent/JP4866522B2/ja not_active Expired - Fee Related
- 2000-08-29 CA CA002382294A patent/CA2382294C/fr not_active Expired - Fee Related
- 2000-08-29 HR HR20020171A patent/HRP20020171A2/hr not_active Application Discontinuation
- 2000-08-29 ME MEP-2009-78A patent/ME00624B/fr unknown
- 2000-08-29 MX MXPA02002041A patent/MXPA02002041A/es active IP Right Grant
- 2000-08-29 HU HU0203197A patent/HU228861B1/hu not_active IP Right Cessation
- 2000-08-29 RS YUP-114/02A patent/RS50148B/sr unknown
- 2000-08-29 SI SI200030478T patent/SI1214061T1/xx unknown
- 2000-08-29 AT AT00964144T patent/ATE269700T1/de active
- 2000-08-29 CN CNB008114501A patent/CN1174748C/zh not_active Expired - Fee Related
- 2000-08-29 SK SK271-2002A patent/SK286378B6/sk not_active IP Right Cessation
- 2000-08-29 UA UA2002021546A patent/UA72927C2/uk unknown
- 2000-08-29 BR BR0013625-5A patent/BR0013625A/pt not_active Application Discontinuation
- 2000-08-29 KR KR1020027002446A patent/KR100670416B1/ko not_active Expired - Fee Related
- 2000-08-29 EP EP00964144A patent/EP1214061B1/fr not_active Expired - Lifetime
- 2000-08-29 EA EA200200313A patent/EA004804B1/ru not_active IP Right Cessation
- 2000-08-29 AU AU75168/00A patent/AU777583B2/en not_active Ceased
2002
- 2002-01-06 IL IL147489A patent/IL147489A/en not_active IP Right Cessation
- 2002-02-19 ZA ZA200201408A patent/ZA200201408B/xx unknown
- 2002-02-20 NO NO20020829A patent/NO328527B1/no not_active IP Right Cessation
- 2002-02-27 US US10/083,565 patent/US20030158249A1/en not_active Abandoned
- 2002-02-28 BG BG106460A patent/BG65913B1/bg unknown
2007
- 2007-06-12 US US11/761,512 patent/US20080045584A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HK1048944A1 (en)	2003-04-25
BR0013625A (pt)	2002-05-14
SI1214061T1 (en)	2004-12-31
EE05124B1 (et)	2009-02-16
EP1214061B1 (fr)	2004-06-23
DK1214061T3 (da)	2004-11-01
NO20020829D0 (no)	2002-02-20
MEP7809A (en)	2011-12-20
CN1174748C (zh)	2004-11-10
UA72927C2 (uk)	2005-05-16
PL353198A1 (en)	2003-11-03
CA2382294A1 (fr)	2001-03-08
KR100670416B1 (ko)	2007-01-17
CN1372466A (zh)	2002-10-02
JP4866522B2 (ja)	2012-02-01
ES2218223T3 (es)	2004-11-16
HUP0203197A2 (hu)	2003-01-28
HU228861B1 (hu)	2013-06-28
BG106460A (bg)	2002-09-30
TW589180B (en)	2004-06-01
US20080045584A1 (en)	2008-02-21
PT1214061E (pt)	2004-09-30
HRP20020171A2 (en)	2004-02-29
ME00624B (fr)	2011-12-20
CZ2002739A3 (cs)	2002-06-12
AU777583B2 (en)	2004-10-21
SK286378B6 (sk)	2008-08-05
HUP0203197A3 (en)	2005-01-28
NO328527B1 (no)	2010-03-08
WO2001015675A2 (fr)	2001-03-08
IL147489A (en)	2006-06-11
PL212612B1 (pl)	2012-10-31
WO2001015675A3 (fr)	2001-09-20
DE60011794T2 (de)	2005-07-14
DE60011794D1 (de)	2004-07-29
IL147489A0 (en)	2002-08-14
ATE269700T1 (de)	2004-07-15
AU7516800A (en)	2001-03-26
NO20020829L (no)	2002-02-20
RS50148B (sr)	2009-05-06
GB9920548D0 (en)	1999-11-03
CZ301378B6 (cs)	2010-02-03
YU11402A (sh)	2005-07-19
KR20020060166A (ko)	2002-07-16
NZ517604A (en)	2004-04-30
EA004804B1 (ru)	2004-08-26
HK1048944B (zh)	2005-04-22
US20030158249A1 (en)	2003-08-21
MXPA02002041A (es)	2002-08-20
SK2712002A3 (en)	2002-07-02
BG65913B1 (bg)	2010-05-31
EA200200313A1 (ru)	2002-08-29
CA2382294C (fr)	2008-06-03
JP2003508427A (ja)	2003-03-04
EP1214061A2 (fr)	2002-06-19
EE200200087A (et)	2003-04-15

Publication	Publication Date	Title
IL147489A0 (en)	2002-08-14	Use of docetaxel for treating hepatocellular carcinoma
MXPA03008623A (es)	2004-05-21	Combinacion farmaceutica para el tratamiento del cancer.
GB0223038D0 (en)	2002-11-13	Therapeutic compounds
GB0225474D0 (en)	2002-12-11	Therapeutic agents
MXPA05012323A (es)	2006-01-30	Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
AP1782A (en)	2007-09-28	Use of compounds ?-D or ?-L nucleoside for treating hepatitis C virus.
NZ511201A (en)	2002-11-26	Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby
NZ515567A (en)	2004-03-26	Method for treating chronic pain using MEK inhibitors
MY147643A (en)	2012-12-31	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder
IL162836A (en)	2011-09-27	Peptides and peptidomimetics having anti-proliferative activity and/or that augment nucleic acid damaging agents or treatments and pharmaceutical compositions thereof
GB0020504D0 (en)	2000-10-11	Therapeutic method
WO2004007676A3 (fr)	2004-04-08	Therapie combinee servant a traiter des tumeurs
PL1603584T3 (pl)	2009-02-27	Aplidyna do leczenia szpiczaka mnogiego
PL357179A1 (en)	2004-07-26	Use of 2-methyl-thiazolidin-2,4-dicarboxylic acid (2-mtdc) and/or physiologically compatible salts for treating and/or preventing cancers
MXPA02008870A (es)	2003-06-24	Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos.
WO2002076393A3 (fr)	2003-04-03	Agents antiangionenes, antitumoraux, et chimiopreventifs
GR1004434B (el)	2004-02-03	Χρησηατουαdiclofenacαhααποδεκτωνααλατωνααυτουαγιαατηνααντιμετωπισηατωναεγκαυματων
WO2005094282A3 (fr)	2006-05-11	Therapie combinatoire comprenant la cloretazine™
UA32314A (uk)	2000-12-15	Спосіб лікування некротичного панкреатиту
UA34199A (uk)	2001-02-15	Спосіб лікування пародонтиту
TW200505836A (en)	2005-02-16	Cyclic sulfonamides for inhibition of gamma-secretase
DE60208336D1 (de)	2006-02-02	Kombination von aktiva mit alfuzosin und apomorphin
UA95094C2 (ru)	2011-07-11	Применение бензоконденсированных гетероциклических сульфамидных производных для лечения маниакального синдрома и биполярного расстройства