PL1603584T3 - Aplidyna do leczenia szpiczaka mnogiego - Google Patents

Aplidyna do leczenia szpiczaka mnogiego

Info

Publication number: PL1603584T3
Authority: PL; Poland
Prior art keywords: aplidine; multiple myeloma; myeloma treatment; treatment; medicament
Prior art date: 2003-03-12

Application number

PL04720081T

Other languages

English (en)

Inventor

Joseph R Bertino

Daniel Medina

Glynn Thomas Faircloth

Constantine S Mitsiades

Kenneth Anderson

Nicholas Mitsiades

Original Assignee

Dana Farber Cancer Inst Inc

Pharma Mar Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-12

Filing date

2004-03-12

Publication date

2009-02-27

2004-03-12 Application filed by Dana Farber Cancer Inst Inc, Pharma Mar Sa filed Critical Dana Farber Cancer Inst Inc

2009-02-27 Publication of PL1603584T3 publication Critical patent/PL1603584T3/pl

Links

UUSZLLQJYRSZIS-LXNNNBEUSA-N plitidepsin Chemical compound CN([C@H](CC(C)C)C(=O)N[C@@H]1C(=O)N[C@@H]([C@H](CC(=O)O[C@H](C(=O)[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(OC)=CC=2)C(=O)O[C@@H]1C)C(C)C)O)[C@@H](C)CC)C(=O)[C@@H]1CCCN1C(=O)C(C)=O UUSZLLQJYRSZIS-LXNNNBEUSA-N 0.000 title abstract 3
208000034578 Multiple myelomas Diseases 0.000 title abstract 2
206010035226 Plasma cell myeloma Diseases 0.000 title abstract 2
229950008499 plitidepsin Drugs 0.000 title abstract 2
108010049948 plitidepsin Proteins 0.000 title abstract 2
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PL04720081T 2003-03-12 2004-03-12 Aplidyna do leczenia szpiczaka mnogiego PL1603584T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US45412503P	2003-03-12	2003-03-12
US52029303P	2003-11-14	2003-11-14
PCT/GB2004/001062 WO2004080477A1 (en)	2003-03-12	2004-03-12	Aplidine for multiple myeloma treatment
EP04720081A EP1603584B1 (en)	2003-03-12	2004-03-12	Aplidine for multiple myeloma treatment

Publications (1)

Publication Number	Publication Date
PL1603584T3 true PL1603584T3 (pl)	2009-02-27

Family

ID=32994545

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04720081T PL1603584T3 (pl)	2003-03-12	2004-03-12	Aplidyna do leczenia szpiczaka mnogiego

Country Status (20)

Country	Link
US (1)	US7381703B2 (pl)
EP (1)	EP1603584B1 (pl)
JP (1)	JP4584245B2 (pl)
KR (1)	KR101160320B1 (pl)
AT (1)	ATE406171T1 (pl)
AU (1)	AU2004218883B2 (pl)
CA (1)	CA2519789C (pl)
CY (1)	CY1108599T1 (pl)
DE (1)	DE602004016126D1 (pl)
DK (1)	DK1603584T3 (pl)
ES (1)	ES2312979T3 (pl)
IL (1)	IL170136A (pl)
MX (1)	MXPA05009742A (pl)
NO (1)	NO334264B1 (pl)
NZ (1)	NZ541611A (pl)
PL (1)	PL1603584T3 (pl)
PT (1)	PT1603584E (pl)
RU (1)	RU2335294C2 (pl)
SI (1)	SI1603584T1 (pl)
WO (1)	WO2004080477A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK287762B6 (sk) *	1999-11-15	2011-09-05	Pharma Mar, S. A.	Použitie aplidínu na prípravu farmaceutického prostriedku na liečenie rakoviny
JP2006519848A (ja)	2003-03-12	2006-08-31	ファルマ・マール・ソシエダード・アノニマ	改良された抗腫瘍治療
EP1942944A2 (en) *	2005-10-31	2008-07-16	Genentech, Inc.	Macrocyclic depsipeptide antibody-drug conjugates and methods
KR20140101014A (ko) *	2006-02-28	2014-08-18	파르마 마르 에스.에이.	개선된 항종양 치료
WO2008080956A1 (en) *	2006-12-29	2008-07-10	Pharma Mar, S.A.	Prognostic molecular markers for the cancer therapy with aplidine
WO2009002553A1 (en) *	2007-06-25	2008-12-31	Prolexys Pharmaceuticals, Inc.	Methods of treating multiple myeloma and resistant cancers
JP2011500650A (ja) *	2007-10-19	2011-01-06	ファルマ・マール・ソシエダード・アノニマ	改良された抗腫瘍治療
EP2262523A1 (en) *	2008-03-07	2010-12-22	Pharma Mar S.A.	Improved anticancer treatments
KR20110028454A (ko) *	2008-05-16	2011-03-18	파르마 마르 에스.에이.	다발성 골수종 치료법
JOP20190254A1 (ar)	2017-04-27	2019-10-27	Pharma Mar Sa	مركبات مضادة للأورام

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4493796A (en)	1980-09-12	1985-01-15	Board Of Trustees, Univ. Of Ill.	Didemnins A, B, C, and derivatives thereof, as antiviral agents
DE3161556D1 (en)	1980-09-12	1984-01-05	Univ Illinois	Novel antibiotics, derivatives thereof, processes for their extraction, and compositions containing them
US4950649A (en)	1980-09-12	1990-08-21	University Of Illinois	Didemnins and nordidemnins
IT1153974B (it)	1982-09-23	1987-01-21	Erba Farmitalia	Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
US4948791A (en)	1989-04-10	1990-08-14	The Board Of Trustees Of The University Of Illinois	Novel Cytotoxic cyclic depsipeptides from the tunicate trididemnum solidum
GB8922026D0 (en) *	1989-09-29	1989-11-15	Pharma Mar Sa	Novel anti-viral and cytotoxic agent
DE4120327A1 (de)	1991-06-20	1992-12-24	Basf Ag	Neue peptide, ihre herstellung und verwendung
US5462726A (en)	1993-12-17	1995-10-31	Bristol-Myers Squibb Company	Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents
WO1995017901A1 (en)	1993-12-29	1995-07-06	Matrix Pharmaceutical, Inc.	Methods and compositions for the treatment of a host with a cellular proliferative disease
EP0706799B1 (en) *	1994-09-16	2001-11-14	MERCK PATENT GmbH	Immunoconjugates II
US5861439A (en)	1994-11-14	1999-01-19	Alza Corporation	Method for enhanced electrotransport agent delivery
ES2102322B1 (es)	1995-07-13	1998-03-01	Pharma Mar Sa	Procedimiento de preparacion de didemnina a.
CA2255615C (en)	1996-05-22	2006-08-29	Neuromedica, Inc.	Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel
US6156724A (en)	1996-06-07	2000-12-05	Rinehart; Kenneth L.	Uses of didemnins as immunomodulating agents
WO1998001353A1 (en)	1996-07-03	1998-01-15	Mckechnie Uk Limited	Container
ATE321773T1 (de)	1996-10-24	2006-04-15	Univ Illinois	Semisynthetisches verfahren zur herstellung von didemninanalogen
EP0956033B1 (en)	1996-10-24	2003-07-23	The Board Of Trustees Of The University Of Illinois	Total synthesis of the amino hip analogue of didemnin a
US6034058A (en)	1997-04-15	2000-03-07	Rinehart; Kenneth L.	Semi-synthetic alanyl dilemnin analogs
AU740598B2 (en)	1997-05-07	2001-11-08	William J. Crumb	Aplidine as an L-type calcium channel enhancer
GB9803448D0 (en) *	1998-02-18	1998-04-15	Pharma Mar Sa	Pharmaceutical formulation
JP4703851B2 (ja)	1998-07-30	2011-06-15	シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ	Ｌ−カルニチンおよびそのアルカノイル誘導体の、抗癌作用を有する医薬品の製造のための使用
US20010021380A1 (en) *	1999-04-19	2001-09-13	Pluenneke John D.	Soluble tumor necrosis factor receptor treatment of medical disorders
US6890904B1 (en)	1999-05-25	2005-05-10	Point Therapeutics, Inc.	Anti-tumor agents
AU781897B2 (en)	1999-05-25	2005-06-23	Point Therapeutics, Inc.	Anti-tumor comprising boroproline compounds
SK287762B6 (sk) *	1999-11-15	2011-09-05	Pharma Mar, S. A.	Použitie aplidínu na prípravu farmaceutického prostriedku na liečenie rakoviny
US6509315B1 (en)	2000-04-07	2003-01-21	The Trustees Of The University Of Pennsylvania	Didemnin analogs and fragments and methods of making and using them
BR0109958A (pt)	2000-04-07	2003-05-27	Univ Pennsylvania	Análogos de didemnina e tamandarina e métodos de preparação e uso deles
UA76718C2 (uk)	2000-06-30	2006-09-15	Фарма Мар, С.А.	Протипухлинні похідні аплідину
WO2002028902A2 (en) *	2000-10-05	2002-04-11	Immunex Corporation	Nectin polypeptides, polynucleotides, methods of making and use thereof
JP2004510824A (ja) *	2000-10-12	2004-04-08	ファルマ・マール・ソシエダード・アノニマ	ガンの治療
AU2002224417A1 (en) *	2000-10-18	2002-04-29	Immunex Corporation	Methods for treating il-18 mediated disorders
EP1351678A2 (en) *	2001-01-02	2003-10-15	Elizabeth Shanahan-Prendergast	Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
AU2002336206B2 (en)	2001-10-19	2007-11-29	Pharma Mar, S.A.	Use of aplidine for the treatment of pancreatic cancer
JP2006519848A (ja)	2003-03-12	2006-08-31	ファルマ・マール・ソシエダード・アノニマ	改良された抗腫瘍治療

2004
- 2004-03-12 WO PCT/GB2004/001062 patent/WO2004080477A1/en not_active Ceased
- 2004-03-12 PL PL04720081T patent/PL1603584T3/pl unknown
- 2004-03-12 AT AT04720081T patent/ATE406171T1/de active
- 2004-03-12 PT PT04720081T patent/PT1603584E/pt unknown
- 2004-03-12 US US10/548,710 patent/US7381703B2/en not_active Expired - Lifetime
- 2004-03-12 DK DK04720081T patent/DK1603584T3/da active
- 2004-03-12 SI SI200430878T patent/SI1603584T1/sl unknown
- 2004-03-12 CA CA2519789A patent/CA2519789C/en not_active Expired - Lifetime
- 2004-03-12 DE DE602004016126T patent/DE602004016126D1/de not_active Expired - Lifetime
- 2004-03-12 ES ES04720081T patent/ES2312979T3/es not_active Expired - Lifetime
- 2004-03-12 MX MXPA05009742A patent/MXPA05009742A/es active IP Right Grant
- 2004-03-12 EP EP04720081A patent/EP1603584B1/en not_active Expired - Lifetime
- 2004-03-12 RU RU2005131578/15A patent/RU2335294C2/ru active
- 2004-03-12 NZ NZ541611A patent/NZ541611A/en not_active IP Right Cessation
- 2004-03-12 AU AU2004218883A patent/AU2004218883B2/en not_active Expired
- 2004-03-12 JP JP2006505957A patent/JP4584245B2/ja not_active Expired - Lifetime
- 2004-03-12 KR KR1020057016966A patent/KR101160320B1/ko not_active Expired - Lifetime
2005
- 2005-08-07 IL IL170136A patent/IL170136A/en active IP Right Grant
- 2005-10-11 NO NO20054668A patent/NO334264B1/no unknown
2008
- 2008-11-26 CY CY20081101367T patent/CY1108599T1/el unknown

Also Published As

Publication number	Publication date
ATE406171T1 (de)	2008-09-15
DK1603584T3 (da)	2009-01-05
WO2004080477A8 (en)	2004-11-11
DE602004016126D1 (de)	2008-10-09
RU2335294C2 (ru)	2008-10-10
ES2312979T3 (es)	2009-03-01
CA2519789A1 (en)	2004-09-23
WO2004080477A1 (en)	2004-09-23
AU2004218883A1 (en)	2004-09-23
AU2004218883B2 (en)	2009-10-01
NZ541611A (en)	2008-04-30
NO20054668L (no)	2005-10-11
EP1603584B1 (en)	2008-08-27
SI1603584T1 (sl)	2009-02-28
US20070149445A9 (en)	2007-06-28
IL170136A (en)	2014-04-30
CA2519789C (en)	2012-07-03
KR101160320B1 (ko)	2012-06-26
PT1603584E (pt)	2008-11-21
MXPA05009742A (es)	2006-05-25
KR20060006779A (ko)	2006-01-19
JP2006519828A (ja)	2006-08-31
RU2005131578A (ru)	2006-01-27
EP1603584A1 (en)	2005-12-14
US20060172926A1 (en)	2006-08-03
US7381703B2 (en)	2008-06-03
NO334264B1 (no)	2014-01-20
JP4584245B2 (ja)	2010-11-17
CY1108599T1 (el)	2014-04-09

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CY1108599T1 (el)	2014-04-09	Η απλιδινη στην αντιμετωπιση του πολλαπλου μυελωματος
TW200637522A (en)	2006-11-01	Skin treatment articles and methods
BR0309665A (pt)	2005-08-16	Tratamento de deficiência de alfa-galactosidase a
GB0201850D0 (en)	2002-03-13	Therapeutic treatment
GB0216321D0 (en)	2002-08-21	Therapeutic treatment
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WO2004080421A3 (en)	2005-06-09	Improved antitumoral treatments
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UA88655C2 (ru)	2009-11-10	S-миртазапин для лечения прилива крови
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IL174134A0 (en)	2006-08-01	Use of a protein in the preparation of a medicament for treatment of fibrotic diseases
GB0327493D0 (en)	2003-12-31	Treatment medicament
DE602005011029D1 (de)	2008-12-24	Therapeutisches mittel zur behandlung von plasmazellneoplasien
MX2007004040A (es)	2007-05-24	Uso para alfa-simpatomimeticos con estructura de 2-imidazolina.
AU2003265321A8 (en)	2003-11-17	Treatments and methods for the treatment, diagnosis and prophylaxis
UA70017A (en)	2004-09-15	Method for conservative treatment of chronic tonsillitis in adults
AU2003209489A1 (en)	2003-09-29	Medical use of captopril for the treatment and prophylaxis of cancer
UA2826U (uk)	2004-08-16	Спосіб лікування розсіяного склерозу