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UA115677C2 - ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ - Google Patents

ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ

Info

Publication number
UA115677C2
UA115677C2 UAA201504530A UAA201504530A UA115677C2 UA 115677 C2 UA115677 C2 UA 115677C2 UA A201504530 A UAA201504530 A UA A201504530A UA A201504530 A UAA201504530 A UA A201504530A UA 115677 C2 UA115677 C2 UA 115677C2
Authority
UA
Ukraine
Prior art keywords
treatment
diseases
pyrimidine
porimals
viral infections
Prior art date
Application number
UAA201504530A
Other languages
English (en)
Inventor
Гоуен Девід Крейг Мак
Стефан Жюльєн Ласт
Серж Марія Алоісіус Пітерс
Вернер Ембрехтс
Тім Х'юго Марія Йонкерс
П'єр Жан-Марі Бернар Рабуассон
Original Assignee
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі filed Critical ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Publication of UA115677C2 publication Critical patent/UA115677C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Даний винахід стосується похідних піроло[3,2-d]піримідину, способів їх одержання, фармацевтичних композицій та їх застосування у лікуванні та/або терапії захворювань.
UAA201504530A 2012-10-10 2013-10-09 ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ UA115677C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12187994 2012-10-10
PCT/EP2013/070990 WO2014056953A1 (en) 2012-10-10 2013-10-09 Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases

Publications (1)

Publication Number Publication Date
UA115677C2 true UA115677C2 (uk) 2017-12-11

Family

ID=47073301

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201504530A UA115677C2 (uk) 2012-10-10 2013-10-09 ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ

Country Status (32)

Country Link
US (3) US9499549B2 (uk)
EP (1) EP2906563B1 (uk)
JP (1) JP6293765B2 (uk)
KR (2) KR102280595B1 (uk)
CN (1) CN104837840B (uk)
AU (1) AU2013328732B2 (uk)
BR (1) BR112015007586B1 (uk)
CA (1) CA2884478C (uk)
CL (1) CL2015000898A1 (uk)
CY (1) CY1120885T1 (uk)
DK (1) DK2906563T3 (uk)
EA (2) EA035327B1 (uk)
ES (1) ES2670513T3 (uk)
HR (1) HRP20180771T1 (uk)
HU (1) HUE037064T2 (uk)
IL (1) IL237761B (uk)
LT (1) LT2906563T (uk)
MX (2) MX365114B (uk)
MY (1) MY179392A (uk)
NO (1) NO2906563T3 (uk)
NZ (1) NZ705589A (uk)
PH (1) PH12015500758A1 (uk)
PL (1) PL2906563T3 (uk)
PT (1) PT2906563T (uk)
RS (1) RS57225B1 (uk)
SG (1) SG11201502622VA (uk)
SI (1) SI2906563T1 (uk)
SM (1) SMT201800257T1 (uk)
TR (1) TR201807076T4 (uk)
UA (1) UA115677C2 (uk)
WO (1) WO2014056953A1 (uk)
ZA (1) ZA201502383B (uk)

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EA036645B1 (ru) 2011-11-09 2020-12-03 Янссен Сайенсиз Айрлэнд Юси Производные пурина для лечения вирусных инфекций
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SI2906563T1 (en) * 2012-10-10 2018-06-29 Janssen Sciences Ireland Uc Derivatives of pyrrolo (3,2-d) pyrimidine for the treatment of viral infections and other diseases
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