TNSN98236A1 - Derives d'erythromycine nouveaux, procede et intermediaires pour leur preparation, et compositions pharmaceutiques les contenant - Google Patents
Derives d'erythromycine nouveaux, procede et intermediaires pour leur preparation, et compositions pharmaceutiques les contenantInfo
- Publication number
- TNSN98236A1 TNSN98236A1 TNTNSN98236A TNSN98236A TNSN98236A1 TN SN98236 A1 TNSN98236 A1 TN SN98236A1 TN TNSN98236 A TNTNSN98236 A TN TNSN98236A TN SN98236 A TNSN98236 A TN SN98236A TN SN98236 A1 TNSN98236 A1 TN SN98236A1
- Authority
- TN
- Tunisia
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- intermediates
- erythromycin derivatives
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
L’INVENTION CONCERNE DES DERIVES D’ERYTHROMYCINE NOUVEAUX, EN PARTICULIER CEUX AVEC DES SUBSTITUANTS R13 NOUVEAUX EN POSITION C-13, AINSI QUE LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES. ELLE CONCERNE EGALEMENT DES PROCEDES POUR LEUR PREPARATION, DES INTERMEDIAIRES UTILES DANS CETTE PREPARATION ET LE COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS COMME AGENTS ANTIBACTERIENS ET ANTIPROTOZOAIRES ET POUR D'AUTRES APPLICATIONS CHEZ DES MAMMIFERES, Y COMPRIS L'HOMME, AINSI QUE CHEZ LES POISSONS ET LES OISEAUX.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7035898P | 1998-01-02 | 1998-01-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN98236A1 true TNSN98236A1 (fr) | 2005-03-15 |
Family
ID=22094819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN98236A TNSN98236A1 (fr) | 1998-01-02 | 1998-12-30 | Derives d'erythromycine nouveaux, procede et intermediaires pour leur preparation, et compositions pharmaceutiques les contenant |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US6825171B2 (fr) |
| EP (2) | EP1044208A1 (fr) |
| JP (1) | JP2002500231A (fr) |
| KR (1) | KR20010033822A (fr) |
| CN (1) | CN1285841A (fr) |
| AP (1) | AP1060A (fr) |
| AR (5) | AR012764A1 (fr) |
| AT (1) | ATE377018T1 (fr) |
| AU (1) | AU759019B2 (fr) |
| BG (1) | BG104640A (fr) |
| BR (1) | BR9812992A (fr) |
| CA (1) | CA2317131C (fr) |
| CO (1) | CO4970773A1 (fr) |
| CZ (1) | CZ20002456A3 (fr) |
| DE (1) | DE69838651T9 (fr) |
| DZ (1) | DZ2699A1 (fr) |
| EA (1) | EA200000600A1 (fr) |
| ES (1) | ES2294641T3 (fr) |
| GT (1) | GT199800207A (fr) |
| HR (1) | HRP20000444A2 (fr) |
| HU (1) | HUP0100566A3 (fr) |
| IL (1) | IL136721A0 (fr) |
| IS (1) | IS5527A (fr) |
| MA (1) | MA26588A1 (fr) |
| NO (1) | NO20003346L (fr) |
| NZ (1) | NZ504987A (fr) |
| OA (1) | OA11440A (fr) |
| PA (1) | PA8465901A1 (fr) |
| PE (1) | PE20000119A1 (fr) |
| PL (1) | PL341647A1 (fr) |
| SK (1) | SK9772000A3 (fr) |
| TN (1) | TNSN98236A1 (fr) |
| UY (2) | UY25331A1 (fr) |
| WO (1) | WO1999035157A1 (fr) |
| YU (1) | YU40900A (fr) |
| ZA (1) | ZA9811940B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
| AP9801420A0 (en) | 1998-01-02 | 1998-12-31 | Pfizer Prod Inc | Novel macrolides. |
| GB9814006D0 (en) | 1998-06-29 | 1998-08-26 | Biotica Tech Ltd | Polyketides and their synthesis |
| WO2000034297A1 (fr) | 1998-12-10 | 2000-06-15 | Pfizer Products Inc. | Antibiotiques a base de cetolides de carbamate et de carbazate |
| EP1749832A3 (fr) * | 1998-12-10 | 2008-03-26 | Pfizer Products Incorporated | Dérivés antibiotiques de carbamate et de carbazate kétolides |
| EP1298138B1 (fr) * | 1998-12-10 | 2006-11-02 | Pfizer Products Inc. | Dérivés anitiobiotiques de Carbamate et de Carbazate Kètolides |
| SI1147121T1 (en) | 1999-01-27 | 2004-04-30 | Pfizer Products Inc. | Ketolide antibiotics |
| EP1754700A3 (fr) | 1999-01-27 | 2007-05-09 | Kosan Biosciences, Inc. | synthese de polycetides |
| US6939861B2 (en) | 1999-04-16 | 2005-09-06 | Kosan Biosciences, Inc. | Amido macrolides |
| CN1373767A (zh) | 1999-04-16 | 2002-10-09 | 奥索-麦克尼尔药品公司 | 酮式大环内酯抗菌剂 |
| US6514944B2 (en) | 1999-04-16 | 2003-02-04 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6590083B1 (en) * | 1999-04-16 | 2003-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | Ketolide antibacterials |
| KR20020007374A (ko) | 1999-04-16 | 2002-01-26 | 추후제출 | 매크롤라이드 항감염제 |
| US6451768B1 (en) * | 1999-04-16 | 2002-09-17 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| SK15162001A3 (sk) * | 1999-05-24 | 2003-02-04 | Pfizer Products Inc. | Deriváty 13-metylerytromycínu |
| ID27331A (id) * | 1999-09-29 | 2001-03-29 | Pfizer Prod Inc | Pembuatan antibiotik-antibiotik ketolida karbamat |
| EP1114826A3 (fr) * | 1999-12-29 | 2001-10-31 | Pfizer Products Inc. | Macrolides antibactériennes et prokinétiques |
| CA2399198A1 (fr) | 2000-02-18 | 2001-08-23 | Christopher Carreras | Composes motilides |
| US20020115621A1 (en) | 2000-08-07 | 2002-08-22 | Wei-Gu Su | Macrolide antibiotics |
| US6472372B1 (en) | 2000-12-06 | 2002-10-29 | Ortho-Mcneil Pharmaceuticals, Inc. | 6-O-Carbamoyl ketolide antibacterials |
| CA2451391A1 (fr) * | 2001-07-03 | 2003-01-16 | Chiron Corporation | Macrolides et cetolides d'erythromycine modifiee c12 a activite antibacterienne |
| EP1430068A1 (fr) | 2001-09-17 | 2004-06-23 | Ortho-Mcneil Pharmaceutical, Inc. | Agents antimicrobiens 6-o-carbamate-11,12-lacto-cetolide |
| IL162292A0 (en) | 2001-12-05 | 2005-11-20 | Ortho Mcneil Pharm Inc | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials |
| CN1671726A (zh) | 2002-05-31 | 2005-09-21 | 詹森药业有限公司 | 3－脱克拉定糖基－6－o－氨基甲酰基和6－o－烷氧基羰基大环内酯抗菌药 |
| JP2006524706A (ja) | 2003-04-25 | 2006-11-02 | カイロン コーポレイション | 新規なケトライド誘導体 |
| DE602005019786D1 (de) * | 2004-12-21 | 2010-04-15 | Pfizer Prod Inc | Makrolide |
| ATE468119T1 (de) | 2006-06-12 | 2010-06-15 | Univ Ramot | Verfahren zur behandlung von krebs |
| SG11201504933WA (en) | 2012-12-24 | 2015-07-30 | Univ Ramot | Agents for treating genetic diseases resulting from nonsense mutations, and methods for identifying the same |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US100518A (en) * | 1870-03-08 | Roland s | ||
| US77302A (en) * | 1868-04-28 | mat son | ||
| US156027A (en) * | 1874-10-20 | Improvement in loom-shuttles | ||
| US61857A (en) * | 1867-02-05 | Improvement in top-drivers or spinners | ||
| US61856A (en) * | 1867-02-05 | Enos s | ||
| US4331803A (en) | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
| YU43006B (en) | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| AU1142383A (en) | 1982-04-26 | 1983-11-03 | Shakas, P.V. | Infant transitional sensory system |
| US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US4998097A (en) | 1983-07-11 | 1991-03-05 | Square D Company | Mechanically operated pressure switch having solid state components |
| JPS61103890A (ja) * | 1984-10-26 | 1986-05-22 | Taisho Pharmaceut Co Ltd | ６−０−メチルエリスロマイシンａ誘導体 |
| US4585759A (en) | 1985-01-22 | 1986-04-29 | Pfizer Inc. | Antibacterial derivatives of a neutral macrolide |
| JPS61229895A (ja) | 1985-04-03 | 1986-10-14 | Nippon Zeon Co Ltd | 保護化デス−ｎ−メチルエリスロマイシン誘導体 |
| ES8800986A1 (es) | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
| US4672056A (en) * | 1985-11-12 | 1987-06-09 | Abbott Laboratories | Erythromycin A derivatives and method of use |
| JPH0633312B2 (ja) | 1986-05-02 | 1994-05-02 | 大正製薬株式会社 | １４−ハイドロキシエリスロマイシン誘導体およびその製造方法 |
| HU198913B (en) | 1987-09-03 | 1989-12-28 | Pliva Pharm & Chem Works | Process for producing 10-dihydro-10-deoxo-11-aza-erythronolide a-derivatives and pharmaceutical compositions containing them as active components |
| GB8726730D0 (en) | 1987-11-14 | 1987-12-16 | Pfizer Ltd | Antiparasitic agents |
| GB8815967D0 (en) | 1988-07-05 | 1988-08-10 | Pfizer Ltd | Antiparasitic agents |
| US4934897A (en) | 1989-02-23 | 1990-06-19 | J. I. Case Company | Pipe-moving apparatus |
| US5141926A (en) | 1990-04-18 | 1992-08-25 | Abbott Laboratories | Erythromycin derivatives |
| IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of erythromycin derivatives |
| US5824513A (en) | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
| WO1993013663A1 (fr) | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Procede permettant d'effectuer la biosynthese de polycetides specifiques |
| US6060234A (en) | 1991-01-17 | 2000-05-09 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| JP3286941B2 (ja) * | 1991-07-09 | 2002-05-27 | 株式会社日立製作所 | ダイヤモンド研削砥石のツルーイング法 |
| US5523399A (en) | 1991-12-27 | 1996-06-04 | Taisho Pharmaceutical Co., Ltd. | 5-O-desosaminylerythronolide derivatives |
| FR2691464B1 (fr) | 1992-05-21 | 1995-06-02 | Roussel Uclaf | Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments. |
| FR2692579B1 (fr) * | 1992-06-19 | 1995-06-02 | Roussel Uclaf | Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments. |
| US5332807A (en) | 1993-04-14 | 1994-07-26 | Merck & Co., Inc. | Process of producing 8A- and 9A-azalide antibiotics |
| US6066721A (en) | 1995-07-06 | 2000-05-23 | Stanford University | Method to produce novel polyketides |
| US5441939A (en) | 1994-03-04 | 1995-08-15 | Pfizer Inc. | 3"-desmethoxy derivatives of erythromycin and azithromycin |
| FR2718450B1 (fr) | 1994-04-08 | 1997-01-10 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| US5486697A (en) | 1994-11-14 | 1996-01-23 | California Institute Of Technology | Array of micro-machined mass energy micro-filters for charged particles |
| FR2732023B1 (fr) * | 1995-03-22 | 1997-04-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| FR2732684B1 (fr) * | 1995-04-06 | 1997-04-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| US5801032A (en) | 1995-08-03 | 1998-09-01 | Abbott Laboratories | Vectors and process for producing high purity 6,12-dideoxyerythromycin A by fermentation |
| WO1997008266A1 (fr) | 1995-08-22 | 1997-03-06 | Mobil Oil Corporation | Procede de viscoreduction utilisant des plastiques en tant que matiere de depart associee |
| EP0876388B1 (fr) | 1995-11-08 | 2004-02-18 | Abbott Laboratories | Derives tricycliques d'erythromycine |
| US6077943A (en) | 1996-03-01 | 2000-06-20 | Takeda Chemical Industries, Ltd. | Method of producing erythromycin derivative |
| US5719272A (en) * | 1996-04-02 | 1998-02-17 | Abbott Laboratories | 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives |
| US5750510A (en) | 1997-04-04 | 1998-05-12 | Abbott Laboratories | 3-descladinose-2,3-anhydroerythromycin derivatives |
| US6271255B1 (en) | 1996-07-05 | 2001-08-07 | Biotica Technology Limited | Erythromycins and process for their preparation |
| EA001744B1 (ru) | 1996-07-05 | 2001-08-27 | Байотика Текнолоджи Лимитед (Gb) | Новые эритромицины и способы их получения |
| CN1273475C (zh) | 1996-09-04 | 2006-09-06 | 艾博特公司 | 具有抗细菌活性的6－0－取代的酮基内酯类化合物 |
| FR2754821B1 (fr) | 1996-10-23 | 2003-04-04 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| NL1006540C2 (nl) | 1997-07-10 | 1999-01-15 | Skf Ind Trading & Dev | Elektrische actuator met regelsensor, alsmede schijfrem omvattende een dergelijke actuator. |
| DE69833838T2 (de) | 1997-08-28 | 2006-11-09 | Supersensor (Pty) Ltd. | Auslesevorrichtung für ein elektronisches Identifizierungssystem |
| US6034069A (en) * | 1997-09-30 | 2000-03-07 | Abbott Laboratories | 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity |
| AP9801420A0 (en) | 1998-01-02 | 1998-12-31 | Pfizer Prod Inc | Novel macrolides. |
| AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
| EP0941998B1 (fr) | 1998-03-03 | 2004-09-01 | Pfizer Products Inc. | Antibiotiques macrolides de type 3,6-cétal |
| US5975370A (en) * | 1998-03-16 | 1999-11-02 | Owens-Illinois Closure Inc. | Tamper-evident plunger-hold-down attachment for pump dispenser |
| US6043227A (en) | 1998-08-19 | 2000-03-28 | Pfizer Inc. | C11 carbamates of macrolide antibacterials |
| US6100240A (en) | 1998-10-09 | 2000-08-08 | Pfizer Inc | Macrolide derivatives |
| US6262030B1 (en) * | 1998-11-03 | 2001-07-17 | Pfizer Inc. | Erythromycin derivatives |
| SI1147121T1 (en) | 1999-01-27 | 2004-04-30 | Pfizer Products Inc. | Ketolide antibiotics |
| AU2753800A (en) | 1999-02-05 | 2000-08-25 | Wrair Walter Reed Army Institute Of Research | Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes |
| KR20020007374A (ko) | 1999-04-16 | 2002-01-26 | 추후제출 | 매크롤라이드 항감염제 |
| CN1373767A (zh) | 1999-04-16 | 2002-10-09 | 奥索-麦克尼尔药品公司 | 酮式大环内酯抗菌剂 |
| US20020061857A1 (en) | 1999-04-23 | 2002-05-23 | Yong-Jin Wu | 9-amino-3-oxo erythromycin derivatives |
| US20020077302A1 (en) | 1999-04-23 | 2002-06-20 | Yong-Jin Wu | Tricyclic erythromycin derivatives |
| SK15162001A3 (sk) | 1999-05-24 | 2003-02-04 | Pfizer Products Inc. | Deriváty 13-metylerytromycínu |
| EP1101769A3 (fr) | 1999-11-18 | 2001-10-24 | Pfizer Products Inc. | Dérivés de l'érythromycine contenant de l'azote |
| US20020061856A1 (en) | 2000-04-24 | 2002-05-23 | Yong-Jin Wu | Novel tricyclic erythromycin derivatives |
| JP2005050903A (ja) | 2003-07-30 | 2005-02-24 | Toshiba Corp | 半導体装置およびその製造方法 |
-
1998
- 1998-12-17 AP APAP/P/1998/001421A patent/AP1060A/en active
- 1998-12-21 NZ NZ504987A patent/NZ504987A/xx unknown
- 1998-12-21 CA CA002317131A patent/CA2317131C/fr not_active Expired - Fee Related
- 1998-12-21 HR HR20000444A patent/HRP20000444A2/hr not_active Application Discontinuation
- 1998-12-21 EA EA200000600A patent/EA200000600A1/ru unknown
- 1998-12-21 WO PCT/IB1998/002100 patent/WO1999035157A1/fr not_active Ceased
- 1998-12-21 EP EP98959099A patent/EP1044208A1/fr not_active Withdrawn
- 1998-12-21 KR KR1020007007378A patent/KR20010033822A/ko not_active Ceased
- 1998-12-21 JP JP2000527553A patent/JP2002500231A/ja active Pending
- 1998-12-21 AU AU15015/99A patent/AU759019B2/en not_active Ceased
- 1998-12-21 PL PL98341647A patent/PL341647A1/xx unknown
- 1998-12-21 IL IL13672198A patent/IL136721A0/xx unknown
- 1998-12-21 CN CN98812832A patent/CN1285841A/zh active Pending
- 1998-12-21 YU YU40900A patent/YU40900A/sh unknown
- 1998-12-21 HU HU0100566A patent/HUP0100566A3/hu unknown
- 1998-12-21 DE DE69838651T patent/DE69838651T9/de not_active Expired - Fee Related
- 1998-12-21 EP EP05106836A patent/EP1642901B1/fr not_active Expired - Lifetime
- 1998-12-21 BR BR9812992-9A patent/BR9812992A/pt not_active Application Discontinuation
- 1998-12-21 SK SK977-2000A patent/SK9772000A3/sk unknown
- 1998-12-21 ES ES05106836T patent/ES2294641T3/es not_active Expired - Lifetime
- 1998-12-21 AT AT05106836T patent/ATE377018T1/de not_active IP Right Cessation
- 1998-12-21 CZ CZ20002456A patent/CZ20002456A3/cs unknown
- 1998-12-28 PE PE1998001285A patent/PE20000119A1/es not_active Application Discontinuation
- 1998-12-29 AR ARP980106716A patent/AR012764A1/es not_active Application Discontinuation
- 1998-12-30 TN TNTNSN98236A patent/TNSN98236A1/fr unknown
- 1998-12-30 DZ DZ980309A patent/DZ2699A1/fr active
- 1998-12-30 MA MA25408A patent/MA26588A1/fr unknown
- 1998-12-30 ZA ZA9811940A patent/ZA9811940B/xx unknown
- 1998-12-30 GT GT199800207A patent/GT199800207A/es unknown
- 1998-12-30 CO CO98077582A patent/CO4970773A1/es unknown
- 1998-12-30 PA PA19988465901A patent/PA8465901A1/es unknown
- 1998-12-30 UY UY25331A patent/UY25331A1/es not_active Application Discontinuation
-
1999
- 1999-06-25 UY UY25587A patent/UY25587A1/es not_active Application Discontinuation
- 1999-11-30 AR ARP990106083A patent/AR019789A2/es not_active Application Discontinuation
- 1999-11-30 AR ARP990106085A patent/AR020016A2/es not_active Application Discontinuation
- 1999-11-30 AR ARP990106082A patent/AR019788A2/es not_active Application Discontinuation
- 1999-11-30 AR ARP990106084A patent/AR019790A2/es not_active Application Discontinuation
-
2000
- 2000-06-09 IS IS5527A patent/IS5527A/is unknown
- 2000-06-27 NO NO20003346A patent/NO20003346L/no unknown
- 2000-06-30 OA OA1200000194A patent/OA11440A/en unknown
- 2000-07-27 BG BG104640A patent/BG104640A/xx unknown
-
2003
- 2003-04-08 US US10/409,016 patent/US6825171B2/en not_active Expired - Fee Related
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