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SI3038633T1 - Stabilni polipeptidi, vezani na humani komplement C5 - Google Patents

Stabilni polipeptidi, vezani na humani komplement C5

Info

Publication number
SI3038633T1
SI3038633T1 SI201431739T SI201431739T SI3038633T1 SI 3038633 T1 SI3038633 T1 SI 3038633T1 SI 201431739 T SI201431739 T SI 201431739T SI 201431739 T SI201431739 T SI 201431739T SI 3038633 T1 SI3038633 T1 SI 3038633T1
Authority
SI
Slovenia
Prior art keywords
human complement
polypeptides binding
stable polypeptides
stable
binding
Prior art date
Application number
SI201431739T
Other languages
English (en)
Inventor
Joakim Nilsson
Erik Nordling
Patrik Stromberg
Original Assignee
Ipc Research, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipc Research, Llc filed Critical Ipc Research, Llc
Publication of SI3038633T1 publication Critical patent/SI3038633T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
SI201431739T 2013-08-28 2014-08-28 Stabilni polipeptidi, vezani na humani komplement C5 SI3038633T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1350986 2013-08-28
EP14765883.5A EP3038633B1 (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5
PCT/EP2014/068282 WO2015028558A1 (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5

Publications (1)

Publication Number Publication Date
SI3038633T1 true SI3038633T1 (sl) 2021-05-31

Family

ID=51539238

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201431739T SI3038633T1 (sl) 2013-08-28 2014-08-28 Stabilni polipeptidi, vezani na humani komplement C5

Country Status (29)

Country Link
US (1) US9994626B2 (sl)
EP (2) EP3811961B1 (sl)
JP (2) JP6767865B2 (sl)
KR (1) KR102446636B1 (sl)
CN (1) CN105658228B (sl)
AU (1) AU2014314222B2 (sl)
BR (1) BR112016003142A2 (sl)
CA (1) CA2926976C (sl)
CY (1) CY1123732T1 (sl)
DK (1) DK3038633T3 (sl)
ES (1) ES2842105T3 (sl)
HR (1) HRP20210013T1 (sl)
HU (1) HUE052613T2 (sl)
IL (1) IL244218A (sl)
LT (1) LT3038633T (sl)
MX (1) MX382140B (sl)
MY (1) MY173804A (sl)
NZ (1) NZ718153A (sl)
PH (1) PH12016500371A1 (sl)
PL (1) PL3038633T3 (sl)
PT (1) PT3038633T (sl)
RS (1) RS61347B1 (sl)
RU (2) RU2733897C2 (sl)
SA (1) SA516370622B1 (sl)
SG (1) SG11201602679VA (sl)
SI (1) SI3038633T1 (sl)
SM (1) SMT202100006T1 (sl)
UA (1) UA117933C2 (sl)
WO (1) WO2015028558A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2817329T3 (en) 2012-02-20 2019-04-01 Swedish Orphan Biovitrum Ab Publ Polypeptides Binding to Human Complement Component C5.
DK3038633T3 (da) * 2013-08-28 2021-01-11 Ipc Res Llc Stabile polypeptider der binder til human komplement c5
KR102497083B1 (ko) 2013-08-28 2023-02-07 애피바디 에이비 돌연변이된 스캐폴드를 갖는 결합 폴리펩티드
UY37651A (es) * 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
IL271920B2 (en) 2017-07-11 2024-03-01 Alexion Pharma Inc Polypeptides that bind complement component c5 or serum albumin and fusion proteins thereof
WO2023077139A1 (en) * 2021-11-01 2023-05-04 Ipc Research, Llc Administration of c5-binding proteins
WO2024227886A1 (en) 2023-05-02 2024-11-07 Mebrahtu Aman Bispecific binding molecule

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE509359C2 (sv) 1989-08-01 1999-01-18 Cemu Bioteknik Ab Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
US6074642A (en) 1994-05-02 2000-06-13 Alexion Pharmaceuticals, Inc. Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
DK1325033T3 (da) 2000-10-10 2010-04-06 Genentech Inc Inhibering af komplement C5 aktivering til behandlingen og forebyggelsen af forsinket xenograf- eller akut vaskulær afstødning
AT410798B (de) * 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
CN100391537C (zh) * 2001-08-17 2008-06-04 建南德克公司 结合至c5和c5a但不阻止c5b形成的补体途径抑制剂
ITMI20021527A1 (it) 2002-07-11 2004-01-12 Consiglio Nazionale Ricerche Anticorpi anti componente c5 del complemento e loro uso
WO2005023866A2 (en) 2003-09-10 2005-03-17 Baxter International Inc. Peptides that inhibit complement activation
SE0400274D0 (sv) * 2004-02-09 2004-02-09 Affibody Ab New polypeptide
GB0518443D0 (en) * 2005-09-09 2005-10-19 Evolutec Ltd Method of treating myasthenia gravis
SI2596807T1 (sl) * 2006-03-08 2016-03-31 Archemix Llc Komplement vezavni aptameri in sredstva proti C5, uporabni pri zdravljenju očesnih motenj
EP3167888B1 (en) 2006-03-15 2024-05-01 Alexion Pharmaceuticals, Inc. Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement
EP2190863B1 (en) 2007-07-31 2015-09-02 Affibody AB New albumin binding compositions, methods and uses
US9187535B2 (en) 2007-12-19 2015-11-17 Affibody Ab Polypeptide derived from protein A and able to bind PDGF
ATE527353T1 (de) * 2007-12-19 2011-10-15 Affibody Ab Pdgf-bindendes polypeptid aus protein a
EP2072525A1 (en) 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
HRP20150799T1 (hr) 2008-08-05 2015-09-11 Novartis Ag Sastavi i postupci za protutijela protiv komplementnog proteina c5
EP2327725A1 (en) 2009-11-26 2011-06-01 InflaRx GmbH Anti-C5a binding moieties with high blocking activity
MY161679A (en) * 2010-07-09 2017-05-15 Affibody Ab Polypeptides
DK2817329T3 (en) * 2012-02-20 2019-04-01 Swedish Orphan Biovitrum Ab Publ Polypeptides Binding to Human Complement Component C5.
JP5980104B2 (ja) 2012-11-22 2016-08-31 三菱電機株式会社 液晶表示装置の製造方法および液晶表示装置の製造システム
US9957330B2 (en) 2012-12-19 2018-05-01 Affibody Ab Polypeptides
KR102497083B1 (ko) * 2013-08-28 2023-02-07 애피바디 에이비 돌연변이된 스캐폴드를 갖는 결합 폴리펩티드
DK3038633T3 (da) * 2013-08-28 2021-01-11 Ipc Res Llc Stabile polypeptider der binder til human komplement c5

Also Published As

Publication number Publication date
PH12016500371B1 (en) 2016-05-02
CA2926976A1 (en) 2015-03-05
RS61347B1 (sr) 2021-02-26
SMT202100006T1 (it) 2021-03-15
ES2842105T3 (es) 2021-07-12
BR122023020080A2 (pt) 2023-12-26
HUE052613T2 (hu) 2021-05-28
JP2016529270A (ja) 2016-09-23
SG11201602679VA (en) 2016-05-30
WO2015028558A1 (en) 2015-03-05
PH12016500371A1 (en) 2016-05-02
KR20160048121A (ko) 2016-05-03
US9994626B2 (en) 2018-06-12
HRP20210013T1 (hr) 2021-04-02
EP3811961A1 (en) 2021-04-28
EP3038633B1 (en) 2020-10-14
RU2016111115A (ru) 2017-10-03
CY1123732T1 (el) 2021-10-29
RU2020128977A (ru) 2021-11-30
JP2020172505A (ja) 2020-10-22
CN105658228A (zh) 2016-06-08
MY173804A (en) 2020-02-24
AU2014314222A1 (en) 2016-04-21
MX382140B (es) 2025-03-13
RU2733897C2 (ru) 2020-10-09
RU2016111115A3 (sl) 2018-04-25
EP3811961B1 (en) 2025-08-20
EP3038633A1 (en) 2016-07-06
KR102446636B1 (ko) 2022-09-23
IL244218A (en) 2017-11-30
IL244218A0 (en) 2016-04-21
LT3038633T (lt) 2021-03-25
HK1225656A1 (en) 2017-09-15
US20160311870A1 (en) 2016-10-27
NZ718153A (en) 2022-05-27
SA516370622B1 (ar) 2018-12-23
AU2014314222B2 (en) 2018-05-24
BR112016003142A2 (pt) 2017-10-17
JP6767865B2 (ja) 2020-10-14
CN105658228B (zh) 2020-02-07
UA117933C2 (uk) 2018-10-25
PL3038633T3 (pl) 2021-07-19
DK3038633T3 (da) 2021-01-11
CA2926976C (en) 2023-11-28
MX2016002397A (es) 2016-09-08
PT3038633T (pt) 2021-01-14

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