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ATE527353T1 - Pdgf-bindendes polypeptid aus protein a - Google Patents

Pdgf-bindendes polypeptid aus protein a

Info

Publication number
ATE527353T1
ATE527353T1 AT08862011T AT08862011T ATE527353T1 AT E527353 T1 ATE527353 T1 AT E527353T1 AT 08862011 T AT08862011 T AT 08862011T AT 08862011 T AT08862011 T AT 08862011T AT E527353 T1 ATE527353 T1 AT E527353T1
Authority
AT
Austria
Prior art keywords
pdgf
binding polypeptide
protein
growth factor
factor receptor
Prior art date
Application number
AT08862011T
Other languages
English (en)
Inventor
Malin Lindborg
Elin Gunneriusson
Christofer Lendel
Original Assignee
Affibody Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/002,972 external-priority patent/US8937047B2/en
Priority claimed from EP07150394A external-priority patent/EP2077272A1/de
Application filed by Affibody Ab filed Critical Affibody Ab
Application granted granted Critical
Publication of ATE527353T1 publication Critical patent/ATE527353T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/49Platelet-derived growth factor [PDGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08862011T 2007-12-19 2008-12-17 Pdgf-bindendes polypeptid aus protein a ATE527353T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/002,972 US8937047B2 (en) 2007-12-19 2007-12-19 Biokinetics of fast-clearing polypeptides
EP07150394A EP2077272A1 (de) 2007-12-21 2007-12-21 Polypeptid-Bibliothek mit vorbestimmtem Gerüst
US917107P 2007-12-26 2007-12-26
PCT/EP2008/010776 WO2009077175A1 (en) 2007-12-19 2008-12-17 Polypeptide derived from protein a and able to bind pdgf

Publications (1)

Publication Number Publication Date
ATE527353T1 true ATE527353T1 (de) 2011-10-15

Family

ID=40547476

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08862011T ATE527353T1 (de) 2007-12-19 2008-12-17 Pdgf-bindendes polypeptid aus protein a

Country Status (5)

Country Link
EP (1) EP2231860B1 (de)
AT (1) ATE527353T1 (de)
DK (1) DK2231860T3 (de)
ES (1) ES2373832T3 (de)
WO (1) WO2009077175A1 (de)

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CN103308673B (zh) 2012-03-08 2017-05-31 思芬构技术有限公司 用于预测雌性对象中发生心血管事件的风险的方法
CN103308670B (zh) 2012-03-08 2017-06-09 思芬构技术有限公司 用于预测对象患糖尿病和/或代谢综合征的风险的方法
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JP6382826B2 (ja) 2012-10-25 2018-08-29 アフィボディ・アーベー アルブミン結合ポリペプチド
EP2912051B1 (de) * 2012-10-25 2018-04-18 Affibody AB Verfahren zur trennung von proteinen mit einer albuminbindung
EP2935335B1 (de) * 2012-12-19 2020-10-28 Affibody AB Neue polypeptide
ES2879023T3 (es) 2013-01-08 2021-11-19 Sphingotec Gmbh Niveles en ayunas de la hormona de crecimiento como marcador predictivo de riesgo cardiovascular
US9975943B2 (en) 2013-03-15 2018-05-22 Affibody Ab Polypeptides
WO2014147153A1 (en) 2013-03-20 2014-09-25 Sphingotec Gmbh Adrenomedullin to guide therapy of blood pressure decline
LT3038633T (lt) * 2013-08-28 2021-03-25 Ipc Research, Llc Stabilūs polipeptidai, kurie rišasi prie žmogaus komplemento c5
MX367423B (es) 2013-08-28 2019-08-21 Affibody Ab Polipeptidos de union a c5.
JP6678661B2 (ja) * 2014-06-13 2020-04-08 アフィボディ アクティエボラーグ 新規ポリペプチド
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SI3193930T1 (sl) 2014-09-17 2019-10-30 Affibody Ab Novi polipeptidi
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PL3245224T3 (pl) 2015-01-12 2021-01-25 Affibody Ab Polipeptydy wiążące il-17a
CN107667294B (zh) 2015-04-24 2021-12-17 思芬构技术有限公司 用于预测慢性肾病发生风险的方法
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MA45493A (fr) 2016-06-27 2019-05-01 Aicuris Anti Infective Cures Gmbh Inhibiteurs d'entrée de hcmv.
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EP3309550A1 (de) 2016-10-12 2018-04-18 sphingotec GmbH Verfahren zum nachweis von apolipoprotein e4
EP3339324A1 (de) 2016-12-22 2018-06-27 sphingotec GmbH Anti-adrenomedullin (adm)-antikörper oder anti-adm antikörperfragment oder anti-adm-nicht-ig-gerüst zur verwendung in einer intervention und therapie von verstopfung bei einem darauf angewiesenen patienten
CA3046850A1 (en) 2016-12-16 2018-06-21 Adrenomed Ag Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof
UY37651A (es) 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
AU2018276361A1 (en) 2017-05-30 2019-12-05 Sphingotec Gmbh A method for diagnosing or monitoring kidney function or diagnosing kidney dysfunction
CN109400711B (zh) * 2017-05-31 2022-02-08 四川大学华西医院 一种PDGFRβ靶向性肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
EP4159229A1 (de) 2017-09-25 2023-04-05 AdrenoMed AG Anti-adrenomedullin (adm)-bindemittel zur verwendung in der therapie oder vorbeugung von krankheitssymptomen
JP2021500548A (ja) 2017-10-18 2021-01-07 アドレノメト アクチェンゲゼルシャフト 抗アドレノメデュリン(adm)結合剤での処置下での治療モニタリング
SG11202002391PA (en) 2017-10-24 2020-04-29 Sphingotec Gmbh Selenoprotein p for prediction of a first cardiovascular event
KR102835427B1 (ko) 2017-10-25 2025-07-21 4틴4 파마슈티컬스 게엠베하 특이적 dpp3-에피토프에 대하여 지시되고 이에 결합하는 dpp3 결합제 및 산화적 스트레스와 연관되는 질환 / 급성 병태의 예방 또는 치료에서의 그의 용도
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EP3569614A1 (de) 2018-05-18 2019-11-20 Julius-Maximilians-Universität Würzburg Verbindungen und verfahren zur immobilisierung von myostatin-inhibitoren auf der extrazellulären matrix durch transglutaminase
EP3586865A1 (de) 2018-06-21 2020-01-01 Charité - Universitätsmedizin Berlin Ergänzende anaphylatoxinbindemittel und deren verwendung in der behandlung einer person mit okularer wunde und/oder fibrose
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EP4014049A1 (de) 2019-08-15 2022-06-22 sphingotec GmbH Verfahren zur diagnose oder überwachung der nierenfunktion oder zur diagnose von nierenfunktionsstörungen bei pädiatrischen patienten
EP4552649A3 (de) 2019-08-30 2025-06-25 4TEEN4 Pharmaceuticals GmbH Therapieführung und/oder therapieüberwachung zur behandlung von schock
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EP3871689A1 (de) 2020-02-26 2021-09-01 sphingotec GmbH Anti-adm-antikörper, die an den freien n-terminus binden, für einen beschleunigten übergang von adm-gly zu bio-adm bei patienten mit einem adm-gly/bio-adm-verhältnis über einem schwellenwert und kombination mit vitamin c
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BR112022016843A2 (pt) 2020-02-27 2022-10-11 Adrenomed Ag Ligante antiadrenomedulina (adm) para uso na terapia de pacientes em choque
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Also Published As

Publication number Publication date
EP2231860A1 (de) 2010-09-29
ES2373832T3 (es) 2012-02-09
EP2231860B1 (de) 2011-10-05
WO2009077175A1 (en) 2009-06-25
DK2231860T3 (da) 2011-12-05

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