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SG11201602679VA - Stable polypeptides binding to human complement c5 - Google Patents

Stable polypeptides binding to human complement c5

Info

Publication number
SG11201602679VA
SG11201602679VA SG11201602679VA SG11201602679VA SG11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA
Authority
SG
Singapore
Prior art keywords
human complement
polypeptides binding
stable polypeptides
stable
binding
Prior art date
Application number
SG11201602679VA
Inventor
Joakim Nilsson
Erik Nordling
Patrik Strömberg
Original Assignee
Swedish Orphan Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab Publ filed Critical Swedish Orphan Biovitrum Ab Publ
Publication of SG11201602679VA publication Critical patent/SG11201602679VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
SG11201602679VA 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5 SG11201602679VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1350986 2013-08-28
PCT/EP2014/068282 WO2015028558A1 (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5

Publications (1)

Publication Number Publication Date
SG11201602679VA true SG11201602679VA (en) 2016-05-30

Family

ID=51539238

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602679VA SG11201602679VA (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5

Country Status (29)

Country Link
US (1) US9994626B2 (en)
EP (2) EP3038633B1 (en)
JP (2) JP6767865B2 (en)
KR (1) KR102446636B1 (en)
CN (1) CN105658228B (en)
AU (1) AU2014314222B2 (en)
BR (1) BR112016003142A2 (en)
CA (1) CA2926976C (en)
CY (1) CY1123732T1 (en)
DK (1) DK3038633T3 (en)
ES (1) ES2842105T3 (en)
HR (1) HRP20210013T1 (en)
HU (1) HUE052613T2 (en)
IL (1) IL244218A (en)
LT (1) LT3038633T (en)
MX (1) MX382140B (en)
MY (1) MY173804A (en)
NZ (1) NZ718153A (en)
PH (1) PH12016500371B1 (en)
PL (1) PL3038633T3 (en)
PT (1) PT3038633T (en)
RS (1) RS61347B1 (en)
RU (2) RU2020128977A (en)
SA (1) SA516370622B1 (en)
SG (1) SG11201602679VA (en)
SI (1) SI3038633T1 (en)
SM (1) SMT202100006T1 (en)
UA (1) UA117933C2 (en)
WO (1) WO2015028558A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS58503B1 (en) 2012-02-20 2019-04-30 Swedish Orphan Biovitrum Ab Publ Polypeptides binding to human complement c5
MX367423B (en) * 2013-08-28 2019-08-21 Affibody Ab Binding polypeptides having a mutated scaffold.
LT3038633T (en) * 2013-08-28 2021-03-25 Ipc Research, Llc STABLE POLYPEPTIDES WHICH BIND TO HUMAN COMPLEMENT C5
UY37651A (en) * 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ IL-1R-I UNION POLYPEPTIDE
CN117327188A (en) 2017-07-11 2024-01-02 亚力兄制药公司 Polypeptide binding complement component C5 or serum albumin and fusion protein thereof
WO2022171892A1 (en) * 2021-02-15 2022-08-18 Affibody Ab New her2-binding polypeptide
KR20240134857A (en) * 2021-11-01 2024-09-10 아이피씨 리써치, 엘엘씨 C5-binding protein administration
WO2024227886A1 (en) 2023-05-02 2024-11-07 Mebrahtu Aman Bispecific binding molecule

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE509359C2 (en) 1989-08-01 1999-01-18 Cemu Bioteknik Ab Use of stabilized protein or peptide conjugates for the preparation of a drug
US6074642A (en) 1994-05-02 2000-06-13 Alexion Pharmaceuticals, Inc. Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
CA2424379C (en) 2000-10-10 2013-10-01 Tanox, Inc. Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection
AT410798B (en) * 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh METHOD FOR IDENTIFYING, ISOLATING AND PRODUCING ANTIGENS AGAINST A SPECIFIC PATHOGEN
CN100391537C (en) 2001-08-17 2008-06-04 建南德克公司 Complement pathway inhibitors that bind to C5 and C5A but do not prevent C5B formation
ITMI20021527A1 (en) 2002-07-11 2004-01-12 Consiglio Nazionale Ricerche C5 COMPONENT ANTIBODIES OF COMPLEMENT AND THEIR USE
EP1667702A2 (en) 2003-09-10 2006-06-14 Baxter International Inc., Baxter Healthcare Corp. Peptides that inhibit complement activation
SE0400274D0 (en) * 2004-02-09 2004-02-09 Affibody Ab New polypeptide
GB0518443D0 (en) * 2005-09-09 2005-10-19 Evolutec Ltd Method of treating myasthenia gravis
DK1991275T3 (en) * 2006-03-08 2014-12-08 Archemix Llc Complement aptamers AND ANTI-C5 AGENTS FOR USE IN THE TREATMENT OF EYE DISEASES
HUE066795T2 (en) * 2006-03-15 2024-09-28 Alexion Pharma Inc Treatment of patients with paroxysmal nocturnal haemoglobinuria with a complement inhibitor
US8937153B2 (en) 2007-07-31 2015-01-20 Affibody Ab Compositions, methods and uses
DK2231860T3 (en) * 2007-12-19 2011-12-05 Affibody Ab Polypeptide derived protein A and capable of binding PDGF
US9187535B2 (en) 2007-12-19 2015-11-17 Affibody Ab Polypeptide derived from protein A and able to bind PDGF
EP2072525A1 (en) 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
MX2011001371A (en) 2008-08-05 2011-06-16 Novartis Ag Compositions and methods for antibodies targeting complement protein c5.
EP2327725A1 (en) 2009-11-26 2011-06-01 InflaRx GmbH Anti-C5a binding moieties with high blocking activity
WO2012004384A2 (en) 2010-07-09 2012-01-12 Affibody Ab Polypeptides
RS58503B1 (en) * 2012-02-20 2019-04-30 Swedish Orphan Biovitrum Ab Publ Polypeptides binding to human complement c5
JP5980104B2 (en) 2012-11-22 2016-08-31 三菱電機株式会社 Liquid crystal display device manufacturing method and liquid crystal display device manufacturing system
EP2935335B1 (en) 2012-12-19 2020-10-28 Affibody AB New polypeptides
MX367423B (en) * 2013-08-28 2019-08-21 Affibody Ab Binding polypeptides having a mutated scaffold.
LT3038633T (en) * 2013-08-28 2021-03-25 Ipc Research, Llc STABLE POLYPEPTIDES WHICH BIND TO HUMAN COMPLEMENT C5

Also Published As

Publication number Publication date
PH12016500371A1 (en) 2016-05-02
EP3811961B1 (en) 2025-08-20
SA516370622B1 (en) 2018-12-23
PL3038633T3 (en) 2021-07-19
UA117933C2 (en) 2018-10-25
JP6767865B2 (en) 2020-10-14
EP3038633B1 (en) 2020-10-14
NZ718153A (en) 2022-05-27
MY173804A (en) 2020-02-24
HUE052613T2 (en) 2021-05-28
LT3038633T (en) 2021-03-25
KR102446636B1 (en) 2022-09-23
US9994626B2 (en) 2018-06-12
AU2014314222A1 (en) 2016-04-21
BR122023020080A2 (en) 2023-12-26
CA2926976C (en) 2023-11-28
JP2016529270A (en) 2016-09-23
CN105658228A (en) 2016-06-08
HK1225656A1 (en) 2017-09-15
RU2016111115A3 (en) 2018-04-25
MX382140B (en) 2025-03-13
CA2926976A1 (en) 2015-03-05
RU2020128977A (en) 2021-11-30
SI3038633T1 (en) 2021-05-31
WO2015028558A1 (en) 2015-03-05
PH12016500371B1 (en) 2016-05-02
RS61347B1 (en) 2021-02-26
JP2020172505A (en) 2020-10-22
EP3811961A1 (en) 2021-04-28
US20160311870A1 (en) 2016-10-27
DK3038633T3 (en) 2021-01-11
MX2016002397A (en) 2016-09-08
SMT202100006T1 (en) 2021-03-15
KR20160048121A (en) 2016-05-03
IL244218A (en) 2017-11-30
IL244218A0 (en) 2016-04-21
RU2016111115A (en) 2017-10-03
CN105658228B (en) 2020-02-07
RU2733897C2 (en) 2020-10-09
AU2014314222B2 (en) 2018-05-24
BR112016003142A2 (en) 2017-10-17
ES2842105T3 (en) 2021-07-12
HRP20210013T1 (en) 2021-04-02
EP3038633A1 (en) 2016-07-06
PT3038633T (en) 2021-01-14
CY1123732T1 (en) 2021-10-29

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