SI2610258T1 - Substituirani piperidino-dihidrotienopirimidini - Google Patents

Substituirani piperidino-dihidrotienopirimidini

Info

Publication number: SI2610258T1
Authority: SI; Slovenia
Prior art keywords: substituted piperidino; dihydrothieno; pyrimidines; dihydrothieno pyrimidines; piperidino
Prior art date: 2007-10-19

Application number

SI200831314T

Other languages

English (en)

Inventor

Pascale Pouzet

Klaus Klinder

Ralf Anderskewitz

Horst Dollinger

Dennis Fiegen

Thomas Fox

Rolf Goeggel

Christoph Hoenke

Domnic Martyres

Peter Nickolaus

Original Assignee

Boehringer Ingelheim International Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-19

Filing date

2008-10-16

Publication date

2014-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39154006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2610258(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-10-16 Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh

2014-12-31 Publication of SI2610258T1 publication Critical patent/SI2610258T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Immunology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Otolaryngology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Psychology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SI200831314T 2007-10-19 2008-10-16 Substituirani piperidino-dihidrotienopirimidini SI2610258T1 (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07118901		2007-10-19
EP13154790.3A EP2610258B1 (de)	2007-10-19	2008-10-16	Substituierte Piperidino-Dihydrothienopyrimidine

Publications (1)

Publication Number	Publication Date
SI2610258T1 true SI2610258T1 (sl)	2014-12-31

Family

ID=39154006

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI200831314T SI2610258T1 (sl)	2007-10-19	2008-10-16	Substituirani piperidino-dihidrotienopirimidini
SI200830579T SI2215092T1 (sl)	2007-10-19	2008-10-16	Substituirani piperidino-dihidrotienopirimidini

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SI200830579T SI2215092T1 (sl)	2007-10-19	2008-10-16	Substituirani piperidino-dihidrotienopirimidini

Country Status (33)

Country	Link
US (1)	US8754073B2 (sl)
EP (3)	EP2380891B1 (sl)
JP (2)	JP5150728B2 (sl)
KR (1)	KR101548975B1 (sl)
CN (2)	CN104069112A (sl)
AR (1)	AR069075A1 (sl)
AT (1)	ATE542825T1 (sl)
AU (1)	AU2008313660B2 (sl)
BR (1)	BRPI0818006B8 (sl)
CA (1)	CA2705414C (sl)
CL (1)	CL2008003096A1 (sl)
CY (2)	CY1112703T1 (sl)
DK (2)	DK2215092T3 (sl)
EA (1)	EA019480B1 (sl)
EC (1)	ECSP10010156A (sl)
ES (2)	ES2381452T3 (sl)
HR (2)	HRP20120334T1 (sl)
MA (1)	MA31845B1 (sl)
ME (1)	ME01330B (sl)
MX (1)	MX2010004026A (sl)
MY (1)	MY153979A (sl)
NZ (1)	NZ585346A (sl)
PE (2)	PE20091386A1 (sl)
PL (2)	PL2215092T3 (sl)
PT (2)	PT2610258E (sl)
RS (1)	RS52271B (sl)
SI (2)	SI2610258T1 (sl)
TN (1)	TN2010000175A1 (sl)
TW (1)	TWI421077B (sl)
UA (1)	UA99309C2 (sl)
UY (1)	UY31405A1 (sl)
WO (1)	WO2009050248A1 (sl)
ZA (1)	ZA201001683B (sl)

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EP2205609B1 (de)	2007-10-19	2017-03-29	Boehringer Ingelheim International GmbH	Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
JP5563466B2 (ja)	2007-10-19	2014-07-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規ピペラジノ−ジヒドロチエノピリミジン誘導体
BRPI0818006B8 (pt) *	2007-10-19	2021-05-25	Boehringer Ingelheim Int	compostos de piperidino-di-hidrotienopirimidinas substituídas, uso dos mesmos e formulações farmacêuticas
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DK3700529T3 (da)	2017-10-23	2025-09-22	Boehringer Ingelheim Int	Ny kombination af aktive midler til behandling af progressive fibroserende interstitielle lungesygdomme (pf-ild)
US11299497B2 (en)	2017-12-15	2022-04-12	UNION therapeutics A/S	Substituted tetrahydropyran dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
ES2968822T3 (es)	2017-12-15	2024-05-14	Union Therapeutics As	Azetidina dihidrotienopirimidinas sustituidas y su uso como inhibidores de la fosfodiesterasa
ES2935615T3 (es) *	2017-12-15	2023-03-08	Union Therapeutics As	Azetidina dihidrotienopiridinas sustituidas y su uso como inhibidores de la fosfodiesterasa
WO2020048827A1 (en) *	2018-09-03	2020-03-12	Bayer Aktiengesellschaft	1, 3, 9-triazaspiro[5.5] undecan-2-one compounds
US20230181590A1 (en)	2021-12-09	2023-06-15	Boehringer Ingelheim International Gmbh	New oral pharmaceutical composition and dose regimen for the therapy of progressive fibrosing interstitial lung diseases
IL312742A (en)	2021-12-09	2024-07-01	Boehringer Ingelheim Int	New therapeutic combinations for the treatment of advanced lymphoid interstitial lung diseases
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EP4593838A1 (en)	2022-09-28	2025-08-06	Boehringer Ingelheim International GmbH	Use of biomarkers in the treatment of fibrotic conditions with a pde4b-inhibitor
JP2025534418A (ja) *	2022-09-29	2025-10-15	蘇州愛科百発生物医薬技術有限公司	含窒素縮合複素環化合物、その調製方法、および医薬におけるその使用
IL322980A (en) *	2023-02-28	2025-10-01	Innovstone Therapeutics Ltd	Dihydrothionopyrimidine derivatives and their uses
WO2024208225A1 (zh) *	2023-04-03	2024-10-10	上海壹迪生物技术有限公司	二氢噻吩并嘧啶类化合物、其制备方法和应用
WO2024213089A1 (zh)	2023-04-13	2024-10-17	上海壹迪生物技术有限公司	取代的二氢噻吩并嘧啶类化合物、其制备方法和应用
CN116925099B (zh) *	2023-07-21	2025-06-03	厦门大学	手性二氢噻吩并嘧啶亚砜的制备方法及其应用与其2、4位取代化合物
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Also Published As

Publication number	Publication date
UY31405A1 (es)	2009-05-29
CL2008003096A1 (es)	2010-02-12
MA31845B1 (fr)	2010-11-01
EP2215092A1 (de)	2010-08-11
JP5150728B2 (ja)	2013-02-27
EP2610258B1 (de)	2014-08-27
PL2610258T3 (pl)	2015-02-27
ECSP10010156A (es)	2010-06-29
PE20131463A1 (es)	2013-12-23
MY153979A (en)	2015-04-30
PL2215092T3 (pl)	2012-07-31
ATE542825T1 (de)	2012-02-15
KR20100100807A (ko)	2010-09-15
CA2705414A1 (en)	2009-04-23
BRPI0818006B1 (pt)	2019-10-22
JP2013064001A (ja)	2013-04-11
EP2610258A1 (de)	2013-07-03
WO2009050248A1 (de)	2009-04-23
CA2705414C (en)	2016-05-24
PE20091386A1 (es)	2009-10-17
ES2524910T3 (es)	2014-12-15
JP5615889B2 (ja)	2014-10-29
TN2010000175A1 (fr)	2011-11-11
EA201000609A1 (ru)	2010-10-29
JP2011500640A (ja)	2011-01-06
EP2380891A1 (de)	2011-10-26
DK2215092T3 (da)	2012-05-07
NZ585346A (en)	2011-09-30
CN101827852A (zh)	2010-09-08
UA99309C2 (ru)	2012-08-10
HRP20141153T1 (hr)	2015-02-13
EP2380891B1 (de)	2013-12-11
AU2008313660B2 (en)	2013-11-07
KR101548975B1 (ko)	2015-09-01
PT2610258E (pt)	2014-10-24
BRPI0818006B8 (pt)	2021-05-25
PT2215092E (pt)	2012-04-10
AU2008313660A1 (en)	2009-04-23
ZA201001683B (en)	2010-10-27
CN104069112A (zh)	2014-10-01
CN101827852B (zh)	2014-07-30
US8754073B2 (en)	2014-06-17
ES2381452T3 (es)	2012-05-28
AR069075A1 (es)	2009-12-30
EA019480B1 (ru)	2014-04-30
CY1115858T1 (el)	2017-01-25
EP2215092B1 (de)	2012-01-25
MX2010004026A (es)	2010-04-30
RS52271B (sr)	2012-10-31
US20110021501A1 (en)	2011-01-27
HRP20120334T1 (hr)	2012-05-31
HK1145677A1 (en)	2011-04-29
SI2215092T1 (sl)	2012-04-30
ME01330B (me)	2013-12-20
TW200918074A (en)	2009-05-01
BRPI0818006A2 (pt)	2015-12-22
DK2610258T3 (da)	2014-11-10
TWI421077B (zh)	2014-01-01
CY1112703T1 (el)	2016-02-10

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