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RU2018107150A3 - - Google Patents

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Publication number
RU2018107150A3
RU2018107150A3 RU2018107150A RU2018107150A RU2018107150A3 RU 2018107150 A3 RU2018107150 A3 RU 2018107150A3 RU 2018107150 A RU2018107150 A RU 2018107150A RU 2018107150 A RU2018107150 A RU 2018107150A RU 2018107150 A3 RU2018107150 A3 RU 2018107150A3
Authority
RU
Russia
Application number
RU2018107150A
Other versions
RU2018107150A (ru
RU2751634C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2018107150A publication Critical patent/RU2018107150A/ru
Publication of RU2018107150A3 publication Critical patent/RU2018107150A3/ru
Application granted granted Critical
Publication of RU2751634C2 publication Critical patent/RU2751634C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2018107150A 2015-07-30 2016-07-29 Новый эффективный аминогликозидный антибиотик против бактерий с множественной лекарственной резистентностью RU2751634C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015151250 2015-07-30
JP2015-151250 2015-07-30
PCT/JP2016/072400 WO2017018528A1 (ja) 2015-07-30 2016-07-29 多剤耐性菌に有効な新規アミノグリコシド抗生物質

Publications (3)

Publication Number Publication Date
RU2018107150A RU2018107150A (ru) 2019-08-29
RU2018107150A3 true RU2018107150A3 (ru) 2019-12-27
RU2751634C2 RU2751634C2 (ru) 2021-07-15

Family

ID=57884581

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107150A RU2751634C2 (ru) 2015-07-30 2016-07-29 Новый эффективный аминогликозидный антибиотик против бактерий с множественной лекарственной резистентностью

Country Status (21)

Country Link
US (2) US10617704B2 (ru)
EP (2) EP3498723A1 (ru)
JP (1) JP6938376B2 (ru)
KR (1) KR102590696B1 (ru)
CN (1) CN108026133B (ru)
AR (1) AR105547A1 (ru)
AU (1) AU2016300993B2 (ru)
CA (1) CA2993425A1 (ru)
CL (1) CL2018000228A1 (ru)
CO (1) CO2018001237A2 (ru)
IL (1) IL257151B (ru)
MX (1) MX383996B (ru)
MY (1) MY186959A (ru)
PH (1) PH12018500202B1 (ru)
RU (1) RU2751634C2 (ru)
SA (1) SA518390825B1 (ru)
SG (2) SG11201800510WA (ru)
TW (1) TWI699372B (ru)
UA (1) UA123629C2 (ru)
WO (1) WO2017018528A1 (ru)
ZA (1) ZA201801312B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3498723A1 (en) * 2015-07-30 2019-06-19 Microbial Chemistry Research Foundation New effective aminoglycoside antibiotic for multidrug-resistant bacteria
JP2020055749A (ja) * 2017-01-27 2020-04-09 公益財団法人微生物化学研究会 多剤耐性菌に有効な新規アミノグリコシド抗生物質
WO2018204358A1 (en) * 2017-05-01 2018-11-08 Wayne State University Apramycin derivatives
JP2021138615A (ja) * 2018-05-31 2021-09-16 Meiji Seikaファルマ株式会社 多剤耐性菌に有効なアミノグリコシド抗生物質の製造方法
KR102811984B1 (ko) * 2021-08-04 2025-05-26 서울대학교산학협력단 신규 아미카신 유도체, 이의 제조방법, 및 이의 항균 용도
CN116462721B (zh) * 2023-04-18 2024-02-02 江南大学 抗菌性氨基糖苷衍生物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468513A (en) 1980-09-22 1984-08-28 Eli Lilly And Company 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides
JPS5782398A (en) * 1980-09-22 1982-05-22 Lilly Co Eli 2-deoxystreptamine aminoglycoside derivative
US4424345A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
US4424344A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
JPS5782399A (en) 1980-09-22 1982-05-22 Lilly Co Eli 2-deoxystreptamine aminoglycoside derivative and manufacture
JPS5772998A (en) * 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel appamycin derivative
JPS5772999A (en) 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel 5-deoxyapramycin
US4385585A (en) * 1981-10-27 1983-05-31 Copco, Inc. Teakettle having whistle cap
US4379917A (en) * 1981-12-24 1983-04-12 Eli Lilly And Company 6"-(Substituted)-apramycin antibiotic derivatives and intermediates and starting materials therefor
US4360665A (en) * 1981-12-24 1982-11-23 Eli Lilly And Company 4"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor
US4458065A (en) * 1983-02-17 1984-07-03 Eli Lilly And Company 7-N-(Substituted-apramycin antibiotic derivatives and intermediates therefor
CN101421287A (zh) 2006-04-07 2009-04-29 纳幕尔杜邦公司 脂壳寡糖的化学合成方法
CN102942603B (zh) * 2006-06-02 2016-01-20 明治制果药业株式会社 新的氨基糖苷类抗生素
LT2217610T (lt) 2007-11-21 2017-02-27 Achaogen, Inc. Antibakteriniai aminoglikozidų analogai
TWI472521B (zh) 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc (2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧苄基)苯基)-6-(甲硫)四氫-2h-哌喃-3,4,5-三醇的固體形態與其使用方法
CN111388489A (zh) * 2010-09-13 2020-07-10 苏黎世大学 安普霉素在制备细菌感染性疾病治疗中的应用
WO2013191550A1 (en) * 2012-06-20 2013-12-27 Rijksuniversiteit Groningen Regioselective diazotation of aminoglycosides
RU2491921C1 (ru) 2012-07-11 2013-09-10 Общество с ограниченной ответственностью "Опытно-технологическая фирма "Этрис" Способ лечения мастита у коров в сухостойный период
EP3498723A1 (en) * 2015-07-30 2019-06-19 Microbial Chemistry Research Foundation New effective aminoglycoside antibiotic for multidrug-resistant bacteria

Also Published As

Publication number Publication date
TWI699372B (zh) 2020-07-21
KR20180043791A (ko) 2018-04-30
IL257151B (en) 2021-01-31
AR105547A1 (es) 2017-10-11
AU2016300993A1 (en) 2018-02-15
BR112018001849A2 (pt) 2018-09-18
WO2017018528A1 (ja) 2017-02-02
IL257151A (en) 2018-03-29
RU2018107150A (ru) 2019-08-29
US10617704B2 (en) 2020-04-14
PH12018500202A1 (en) 2018-07-30
MX2018001022A (es) 2018-05-17
SA518390825B1 (ar) 2021-06-01
TW201718616A (zh) 2017-06-01
ZA201801312B (en) 2019-07-31
KR102590696B1 (ko) 2023-10-18
JP6938376B2 (ja) 2021-09-22
MX383996B (es) 2025-03-14
US11135234B2 (en) 2021-10-05
SG10201913231RA (en) 2020-03-30
MY186959A (en) 2021-08-26
RU2751634C2 (ru) 2021-07-15
US20180214470A1 (en) 2018-08-02
HK1254239A1 (zh) 2019-07-12
AU2016300993B2 (en) 2020-07-02
CN108026133B (zh) 2021-05-07
EP3330275A1 (en) 2018-06-06
NZ740037A (en) 2024-08-30
US20200155582A1 (en) 2020-05-21
PH12018500202B1 (en) 2022-02-18
JPWO2017018528A1 (ja) 2018-05-17
SG11201800510WA (en) 2018-02-27
CA2993425A1 (en) 2017-02-02
UA123629C2 (uk) 2021-05-05
EP3498723A1 (en) 2019-06-19
EP3330275A4 (en) 2018-12-05
CO2018001237A2 (es) 2018-05-10
CL2018000228A1 (es) 2018-08-24
CN108026133A (zh) 2018-05-11

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