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PT98532A - Processo para a preparacao de formulacoes solidas para aplicacao oral contendo como ingrediente activo ifosfamida - Google Patents

Processo para a preparacao de formulacoes solidas para aplicacao oral contendo como ingrediente activo ifosfamida

Info

Publication number
PT98532A
PT98532A PT98532A PT9853291A PT98532A PT 98532 A PT98532 A PT 98532A PT 98532 A PT98532 A PT 98532A PT 9853291 A PT9853291 A PT 9853291A PT 98532 A PT98532 A PT 98532A
Authority
PT
Portugal
Prior art keywords
ifosfamide
preparation
active ingredient
solid formulations
oral application
Prior art date
Application number
PT98532A
Other languages
English (en)
Other versions
PT98532B (pt
Inventor
Juergen Engel
Dieter Sauerbier
Eckhard Milsmann
Klaus Molge
Otto Isaac
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of PT98532A publication Critical patent/PT98532A/pt
Publication of PT98532B publication Critical patent/PT98532B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98532A 1990-08-03 1991-08-01 Processo para a preparacao de formulacoes solidas para aplicacao oral contendo como ingrediente activo ifosfamida PT98532B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4024683 1990-08-03
SG181694A SG181694G (en) 1990-08-03 1994-12-30 Solid oral administration forms containing ifosfamide as active agent

Publications (2)

Publication Number Publication Date
PT98532A true PT98532A (pt) 1992-06-30
PT98532B PT98532B (pt) 1999-01-29

Family

ID=25895607

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98532A PT98532B (pt) 1990-08-03 1991-08-01 Processo para a preparacao de formulacoes solidas para aplicacao oral contendo como ingrediente activo ifosfamida

Country Status (33)

Country Link
US (1) US5158776A (pt)
EP (1) EP0469440B1 (pt)
JP (2) JP3061898B2 (pt)
KR (1) KR0177170B1 (pt)
CN (1) CN1046851C (pt)
AR (1) AR247484A1 (pt)
AT (1) ATE110261T1 (pt)
AU (2) AU643309B2 (pt)
BG (1) BG60900B1 (pt)
CA (1) CA2048367C (pt)
CZ (1) CZ280475B6 (pt)
DE (2) DE4124481A1 (pt)
DK (1) DK0469440T3 (pt)
EG (1) EG19690A (pt)
ES (1) ES2058999T3 (pt)
FI (1) FI97951C (pt)
HK (1) HK15695A (pt)
HR (1) HRP920575B1 (pt)
HU (1) HU206268B (pt)
IE (1) IE66378B1 (pt)
IL (1) IL99031A (pt)
LT (1) LT3528B (pt)
LV (1) LV10043B (pt)
MC (1) MC2274A1 (pt)
MX (1) MX9100441A (pt)
NO (1) NO178252C (pt)
NZ (1) NZ239222A (pt)
PT (1) PT98532B (pt)
RO (1) RO113611B1 (pt)
SG (1) SG181694G (pt)
SI (1) SI9111342B (pt)
SK (2) SK279740B6 (pt)
ZA (1) ZA916124B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996010996A1 (en) * 1993-07-21 1996-04-18 The University Of Kentucky Research Foundation A multicompartment hard capsule with control release properties
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
DE19733305A1 (de) * 1997-08-01 1999-02-04 Asta Medica Ag Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin
US6103297A (en) * 1998-01-14 2000-08-15 Matsushita Electronics Corporation Method of manufacturing cathode-ray tube
DE19826517B4 (de) * 1998-06-15 2006-03-23 Baxter Healthcare S.A. Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
SI3091974T1 (sl) * 2014-01-06 2020-08-31 Shield TX (UK) Limited Režim odmerjanja železovega trimaltola
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987204A (en) 1972-09-15 1976-10-19 Sucrest Corporation Direct compression vehicle
JPS5646807A (en) * 1979-09-27 1981-04-28 Japan Atom Energy Res Inst Production of composition of complex gradually releasing physiologically active substance
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US4618692A (en) * 1981-09-03 1986-10-21 Asta-Werke Aktiengesellschaft 4-carbamoyloxy-oxazaphosphorins
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
ES2038623T3 (es) * 1986-07-11 1993-08-01 Asta Medica Aktiengesellschaft Procedimiento para preparar soluciones de oxazafosforinas con estabilidad mejorada.
DE3804686A1 (de) * 1988-02-15 1989-08-24 Henkel Kgaa Arzneimittel mit einer kombination von cytostatika bzw. hormontherapeutika und phosphonoderivaten

Also Published As

Publication number Publication date
BG94934A (bg) 1993-12-24
AR247484A1 (es) 1995-01-31
EG19690A (en) 1995-09-30
AU4483693A (en) 1993-11-11
IL99031A (en) 1996-09-04
DE4124481A1 (de) 1992-02-06
FI97951C (fi) 1997-03-25
CZ280475B6 (cs) 1996-01-17
KR920003963A (ko) 1992-03-27
LTIP921A (en) 1995-03-27
SK279739B6 (sk) 1999-03-12
CA2048367A1 (en) 1992-02-04
BG60900B1 (bg) 1996-06-28
CN1046851C (zh) 1999-12-01
NZ239222A (en) 1993-01-27
LT3528B (en) 1995-11-27
IL99031A0 (en) 1992-07-15
HK15695A (en) 1995-02-10
PT98532B (pt) 1999-01-29
RO113611B1 (ro) 1998-09-30
AU643309B2 (en) 1993-11-11
MX9100441A (es) 1992-04-01
NO178252B (no) 1995-11-13
JP3061898B2 (ja) 2000-07-10
DK0469440T3 (da) 1994-11-14
JP3545300B2 (ja) 2004-07-21
HU206268B (en) 1992-10-28
HUT59316A (en) 1992-05-28
EP0469440B1 (de) 1994-08-24
SK279740B6 (sk) 1999-03-12
CA2048367C (en) 2000-05-23
KR0177170B1 (ko) 1999-03-20
CS240991A3 (en) 1992-03-18
HRP920575A2 (en) 1995-04-30
NO913019D0 (no) 1991-08-02
JPH04243828A (ja) 1992-08-31
CN1058715A (zh) 1992-02-19
AU649184B2 (en) 1994-05-12
HU912594D0 (en) 1992-01-28
LV10043B (en) 1995-06-20
SI9111342B (sl) 1998-10-31
ES2058999T3 (es) 1994-11-01
JP2000229860A (ja) 2000-08-22
SG181694G (en) 1995-05-12
FI97951B (fi) 1996-12-13
FI913710A0 (fi) 1991-08-02
EP0469440A1 (de) 1992-02-05
DE59102620D1 (de) 1994-09-29
FI913710L (fi) 1992-02-04
NO913019L (no) 1992-02-04
SI9111342A (sl) 1998-04-30
US5158776A (en) 1992-10-27
HRP920575B1 (en) 1999-04-30
ZA916124B (en) 1992-04-29
AU8158991A (en) 1992-02-06
LV10043A (lv) 1994-05-10
ATE110261T1 (de) 1994-09-15
IE912774A1 (en) 1992-02-12
MC2274A1 (fr) 1993-06-23
IE66378B1 (en) 1995-12-27
NO178252C (no) 1996-02-21

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920207

FG3A Patent granted, date of granting

Effective date: 19981013

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20110413