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ES2058999T3 - Formas de administracion orales solidas que contienen ifosfamida como sustancia activa. - Google Patents

Formas de administracion orales solidas que contienen ifosfamida como sustancia activa.

Info

Publication number
ES2058999T3
ES2058999T3 ES91112368T ES91112368T ES2058999T3 ES 2058999 T3 ES2058999 T3 ES 2058999T3 ES 91112368 T ES91112368 T ES 91112368T ES 91112368 T ES91112368 T ES 91112368T ES 2058999 T3 ES2058999 T3 ES 2058999T3
Authority
ES
Spain
Prior art keywords
ifosfamide
active substance
solid oral
oral forms
administration containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91112368T
Other languages
English (en)
Inventor
Dieter Sauerbier
Jorgen Dr Engel
Eckhard Dr Milsmann
Klaus Dr Molge
Otto Dr Isaac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2058999T3 publication Critical patent/ES2058999T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PREPARACION DE FOSFAMIDAS FIJOS EN FORMA DE CAPSULA CON LO QUE LA MEDIDA DE LA CAPSULA ESTA COMPUESTA FUNDAMENTALMENTE DE UN ACTIVADOR IFOSFAMIDA Y CELULOSA MICROCRISTALINA O TAMBIEN EN FORMA DE PASTILLAS QUE SE COMPONEN DE UN PESO PARCIAL DE IFOSFAMIDA QUE CONTIENE, 0,1-1,0 DE UN TANTO POR CIENTO DE FOSFATO TRICALCICO Y 0,04-0,4 DE UN TANTO POR CIENTO DE GLICOL DE POLIOTILENO QUE SE AÑADE TAMBIEN REFERIDO AL PESO DE LAS PASTILLAS 5-6% DE UN MEDIO DE REGULACION DE FLUIDO Y DE RELLENO 1-10% DE UN AGENTE EXPLOSIVO 0,1-10% DE UN MEDIO ANTIADHERENTE Y 0,1-80% DE UN MEDIO DE UNION.
ES91112368T 1990-08-03 1991-07-24 Formas de administracion orales solidas que contienen ifosfamida como sustancia activa. Expired - Lifetime ES2058999T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4024683 1990-08-03
SG181694A SG181694G (en) 1990-08-03 1994-12-30 Solid oral administration forms containing ifosfamide as active agent

Publications (1)

Publication Number Publication Date
ES2058999T3 true ES2058999T3 (es) 1994-11-01

Family

ID=25895607

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91112368T Expired - Lifetime ES2058999T3 (es) 1990-08-03 1991-07-24 Formas de administracion orales solidas que contienen ifosfamida como sustancia activa.

Country Status (33)

Country Link
US (1) US5158776A (es)
EP (1) EP0469440B1 (es)
JP (2) JP3061898B2 (es)
KR (1) KR0177170B1 (es)
CN (1) CN1046851C (es)
AR (1) AR247484A1 (es)
AT (1) ATE110261T1 (es)
AU (2) AU643309B2 (es)
BG (1) BG60900B1 (es)
CA (1) CA2048367C (es)
CZ (1) CZ280475B6 (es)
DE (2) DE4124481A1 (es)
DK (1) DK0469440T3 (es)
EG (1) EG19690A (es)
ES (1) ES2058999T3 (es)
FI (1) FI97951C (es)
HK (1) HK15695A (es)
HR (1) HRP920575B1 (es)
HU (1) HU206268B (es)
IE (1) IE66378B1 (es)
IL (1) IL99031A (es)
LT (1) LT3528B (es)
LV (1) LV10043B (es)
MC (1) MC2274A1 (es)
MX (1) MX9100441A (es)
NO (1) NO178252C (es)
NZ (1) NZ239222A (es)
PT (1) PT98532B (es)
RO (1) RO113611B1 (es)
SG (1) SG181694G (es)
SI (1) SI9111342B (es)
SK (2) SK279740B6 (es)
ZA (1) ZA916124B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996010996A1 (en) * 1993-07-21 1996-04-18 The University Of Kentucky Research Foundation A multicompartment hard capsule with control release properties
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
DE19733305A1 (de) * 1997-08-01 1999-02-04 Asta Medica Ag Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin
US6103297A (en) * 1998-01-14 2000-08-15 Matsushita Electronics Corporation Method of manufacturing cathode-ray tube
DE19826517B4 (de) * 1998-06-15 2006-03-23 Baxter Healthcare S.A. Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
SI3091974T1 (sl) * 2014-01-06 2020-08-31 Shield TX (UK) Limited Režim odmerjanja železovega trimaltola
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987204A (en) 1972-09-15 1976-10-19 Sucrest Corporation Direct compression vehicle
JPS5646807A (en) * 1979-09-27 1981-04-28 Japan Atom Energy Res Inst Production of composition of complex gradually releasing physiologically active substance
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US4618692A (en) * 1981-09-03 1986-10-21 Asta-Werke Aktiengesellschaft 4-carbamoyloxy-oxazaphosphorins
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
ES2038623T3 (es) * 1986-07-11 1993-08-01 Asta Medica Aktiengesellschaft Procedimiento para preparar soluciones de oxazafosforinas con estabilidad mejorada.
DE3804686A1 (de) * 1988-02-15 1989-08-24 Henkel Kgaa Arzneimittel mit einer kombination von cytostatika bzw. hormontherapeutika und phosphonoderivaten

Also Published As

Publication number Publication date
BG94934A (bg) 1993-12-24
AR247484A1 (es) 1995-01-31
EG19690A (en) 1995-09-30
AU4483693A (en) 1993-11-11
IL99031A (en) 1996-09-04
DE4124481A1 (de) 1992-02-06
FI97951C (fi) 1997-03-25
CZ280475B6 (cs) 1996-01-17
KR920003963A (ko) 1992-03-27
LTIP921A (en) 1995-03-27
SK279739B6 (sk) 1999-03-12
CA2048367A1 (en) 1992-02-04
BG60900B1 (bg) 1996-06-28
CN1046851C (zh) 1999-12-01
NZ239222A (en) 1993-01-27
LT3528B (en) 1995-11-27
IL99031A0 (en) 1992-07-15
HK15695A (en) 1995-02-10
PT98532B (pt) 1999-01-29
RO113611B1 (ro) 1998-09-30
AU643309B2 (en) 1993-11-11
MX9100441A (es) 1992-04-01
NO178252B (no) 1995-11-13
JP3061898B2 (ja) 2000-07-10
DK0469440T3 (da) 1994-11-14
JP3545300B2 (ja) 2004-07-21
HU206268B (en) 1992-10-28
HUT59316A (en) 1992-05-28
EP0469440B1 (de) 1994-08-24
SK279740B6 (sk) 1999-03-12
CA2048367C (en) 2000-05-23
KR0177170B1 (ko) 1999-03-20
CS240991A3 (en) 1992-03-18
HRP920575A2 (en) 1995-04-30
NO913019D0 (no) 1991-08-02
JPH04243828A (ja) 1992-08-31
CN1058715A (zh) 1992-02-19
AU649184B2 (en) 1994-05-12
HU912594D0 (en) 1992-01-28
LV10043B (en) 1995-06-20
SI9111342B (sl) 1998-10-31
JP2000229860A (ja) 2000-08-22
SG181694G (en) 1995-05-12
FI97951B (fi) 1996-12-13
FI913710A0 (fi) 1991-08-02
EP0469440A1 (de) 1992-02-05
DE59102620D1 (de) 1994-09-29
FI913710L (fi) 1992-02-04
PT98532A (pt) 1992-06-30
NO913019L (no) 1992-02-04
SI9111342A (sl) 1998-04-30
US5158776A (en) 1992-10-27
HRP920575B1 (en) 1999-04-30
ZA916124B (en) 1992-04-29
AU8158991A (en) 1992-02-06
LV10043A (lv) 1994-05-10
ATE110261T1 (de) 1994-09-15
IE912774A1 (en) 1992-02-12
MC2274A1 (fr) 1993-06-23
IE66378B1 (en) 1995-12-27
NO178252C (no) 1996-02-21

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