PL2442814T3 - Bifidobacteria do leczenia cukrzycy i pokrewnych chorób - Google Patents
Bifidobacteria do leczenia cukrzycy i pokrewnych choróbInfo
- Publication number
- PL2442814T3 PL2442814T3 PL10730548T PL10730548T PL2442814T3 PL 2442814 T3 PL2442814 T3 PL 2442814T3 PL 10730548 T PL10730548 T PL 10730548T PL 10730548 T PL10730548 T PL 10730548T PL 2442814 T3 PL2442814 T3 PL 2442814T3
- Authority
- PL
- Poland
- Prior art keywords
- bifidobacteria
- related conditions
- treating diabetes
- diabetes
- treating
- Prior art date
Links
- 241000186000 Bifidobacterium Species 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/515—Animalis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21856309P | 2009-06-19 | 2009-06-19 | |
| EP10730548.4A EP2442814B1 (en) | 2009-06-19 | 2010-06-18 | Bifidobacteria for treating diabetes and related conditions |
| PCT/IB2010/052757 WO2010146568A2 (en) | 2009-06-19 | 2010-06-18 | Bifidobacteria for treating diabetes and related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2442814T3 true PL2442814T3 (pl) | 2019-04-30 |
Family
ID=42989263
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10730548T PL2442814T3 (pl) | 2009-06-19 | 2010-06-18 | Bifidobacteria do leczenia cukrzycy i pokrewnych chorób |
| PL17155654T PL3181134T3 (pl) | 2009-06-19 | 2010-06-18 | Bifidobakterie do leczenia cukrzycy i stanów pokrewnych |
| PL14179491T PL2808024T3 (pl) | 2009-06-19 | 2010-06-18 | Bifidobakterie do leczenia zastoinowej niewydolności serca |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17155654T PL3181134T3 (pl) | 2009-06-19 | 2010-06-18 | Bifidobakterie do leczenia cukrzycy i stanów pokrewnych |
| PL14179491T PL2808024T3 (pl) | 2009-06-19 | 2010-06-18 | Bifidobakterie do leczenia zastoinowej niewydolności serca |
Country Status (7)
| Country | Link |
|---|---|
| US (8) | US20120107291A1 (pl) |
| EP (3) | EP3181134B1 (pl) |
| CN (5) | CN104784694A (pl) |
| DK (3) | DK3181134T3 (pl) |
| ES (3) | ES2763137T3 (pl) |
| PL (3) | PL2442814T3 (pl) |
| WO (1) | WO2010146568A2 (pl) |
Families Citing this family (75)
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| CN102670661B (zh) * | 2011-03-08 | 2013-10-02 | 惠宏襄 | 用于刺激胰高血糖素样肽-1分泌的药物 |
| ITMI20111488A1 (it) | 2011-08-03 | 2013-02-04 | Gnosis Spa | Formulazioni comprendenti saccharomyces boulardii e superossido dismutasi (sod) per controllare l'obesita' |
| CN103082292B (zh) * | 2011-11-02 | 2015-03-04 | 深圳华大基因研究院 | 罗斯氏菌(Roseburia)在治疗和预防肥胖相关疾病中的应用 |
| IN2014DN07752A (pl) | 2012-02-29 | 2015-05-15 | Ethicon Endo Surgery Inc | |
| CN102792919B (zh) * | 2012-08-08 | 2015-09-09 | 上海交通大学 | 悉生动物肥胖模型的构建方法及其应用 |
| AU2013314410B2 (en) * | 2012-09-11 | 2017-02-23 | Thylabisco Ab | Prebiotic thylakoid composition |
| KR20150118084A (ko) * | 2012-09-20 | 2015-10-21 | 프로테라 인코포레이티드 | 비만 및 비만 관련 질환을 치료하기 위한 프로바이오틱 조성물 및 방법 |
| US20150328266A1 (en) * | 2012-12-20 | 2015-11-19 | Tufts University | Use of Bifidobacterium Animalis for Treating or Preventing Body Weight Gain and Insulin Resistance |
| ES2526986B1 (es) * | 2013-07-18 | 2015-11-02 | Biopolis, S.L. | Nueva cepa de Bifidobacterium animalis subsp. lactis CECT 8145 y su uso para el tratamiento y/o prevención de sobrepeso y obesidad y enfermedades asociadas |
| GB2535034A (en) | 2013-07-21 | 2016-08-10 | Whole Biome Inc | Methods and systems for microbiome characterization, monitoring and treatment |
| WO2015051323A1 (en) * | 2013-10-03 | 2015-04-09 | Trustees Of The University Of Pennsylvania | Compositions comprising a defined microbiome and methods of use thereof |
| US10058576B2 (en) | 2013-10-03 | 2018-08-28 | The Trustees Of The University Of Pennsylvania | Compositions and methods comprising a defined microbiome and methods of use thereof |
| WO2015121455A1 (fr) * | 2014-02-14 | 2015-08-20 | Vesale Pharma Sa | Composition comprenant au moins un probiotique |
| EP3104868A2 (fr) * | 2014-02-14 | 2016-12-21 | Vesale Pharma Sa | Utilisations de compositions comprenant du bifidobacterium animalis ssp. lactis lmg p-28149 |
| BE1000016B1 (fr) * | 2014-04-25 | 2016-02-01 | Vesale Pharma Nv | Composition comprenant du bifidobacterium animalis ssp. lactis. |
| WO2015121458A2 (fr) * | 2014-02-14 | 2015-08-20 | Vesale Pharma Sa | Composition comprenant du bifidobacterium animalis ssp. lactis |
| BE1000017B1 (fr) * | 2014-04-25 | 2016-01-21 | Vesale Pharma Nv | Composition comprenant au moins un probiotique |
| MX385029B (es) * | 2014-08-08 | 2025-03-14 | Soc Des Produits Nestle S A Star | Una combinacion de vitamina d y zinc y su uso. |
| WO2016020486A1 (en) * | 2014-08-08 | 2016-02-11 | Nestec S.A. | A combination of myo-inositol and zinc and its use |
| TWI572713B (zh) * | 2014-10-31 | 2017-03-01 | 豐華生物科技股份有限公司 | 抗肥胖之乳酸菌菌株及其於食品組成物以及醫藥組成物之應用 |
| SG10201903823QA (en) | 2014-10-31 | 2019-05-30 | Whole Biome Inc | Methods and compositions relating to microbial treatment and diagnosis of disorders |
| KR102735818B1 (ko) | 2015-01-23 | 2024-11-28 | 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 암 예방에서 단쇄 지방산의 용도 |
| GB201514303D0 (en) * | 2015-07-16 | 2015-09-23 | Dupont Nutrition Biosci Aps | Bifidobacteria for treating cardiac conditions |
| GB201514302D0 (en) * | 2015-07-16 | 2015-09-23 | Dupont Nutrition Biosci Aps | Lactobacilli for treating cardiac dysfunction |
| US9980491B2 (en) * | 2015-07-25 | 2018-05-29 | Siobhan Reilly | Probiotic compositions and methods of use |
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| CN106619742A (zh) * | 2016-11-08 | 2017-05-10 | 江西益盟科技有限公司 | 治疗糖尿病的乳酸菌组合物及其制备方法 |
| WO2018104263A1 (en) * | 2016-12-06 | 2018-06-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of enhancing the potency of incretin-based drugs in subjects in need thereof |
| CA3052134C (en) * | 2017-01-31 | 2023-01-03 | University-Industry Cooperation Group Of Kyung Hee University | Novel lactic acid bacteria and use thereof |
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| CN106617096B (zh) * | 2017-02-15 | 2020-12-18 | 中国农业大学 | 一种增强胰岛功能的双歧杆菌及其应用 |
| CN107050065B (zh) * | 2017-03-31 | 2021-03-30 | 杭州远大生物制药有限公司 | 双歧四联活菌组合物的新应用 |
| CN107410486A (zh) * | 2017-06-27 | 2017-12-01 | 合肥工业大学 | 一种降血糖玫瑰茄发酵乳的制备方法 |
| BR112019028007A2 (pt) * | 2017-06-30 | 2020-07-07 | N.V. Nutricia | composição nutricional, uso de uma combinação de bifidobacterium breve e oligossacarídeos não digeríveis, e método para prevenir e/ou reduzir o risco de ocorrência de doença hepática gordurosa |
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| CN107723257A (zh) * | 2017-09-20 | 2018-02-23 | 深圳市晨光乳业有限公司 | 一种动物双歧杆菌及其食品组合物 |
| WO2019067087A1 (en) * | 2017-09-26 | 2019-04-04 | Second Genome, Inc. | GEMELLA SANGUINIS AS BIOTHERAPEUTIC AGENTS |
| WO2019087280A1 (ja) * | 2017-10-31 | 2019-05-09 | 森永乳業株式会社 | 筋肉増量用組成物 |
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| CN112888448B (zh) * | 2018-12-07 | 2023-07-25 | 深圳华大生命科学研究院 | 单形巨单胞菌在预防和/或治疗代谢性疾病中的用途 |
| CN109998113A (zh) * | 2019-04-18 | 2019-07-12 | 广东省微生物研究所(广东省微生物分析检测中心) | 一种具有降血糖功效的益生菌制剂的功能性食品 |
| CN110150669B (zh) * | 2019-04-29 | 2022-09-06 | 河北一然生物科技股份有限公司 | 一种适于糖尿病患者食用的益生菌组合物及其应用 |
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| CN113995720B (zh) * | 2021-11-15 | 2023-03-17 | 郑州大学 | 一种乳剂包被型益生菌制剂及其制备方法与应用 |
| CN115466689B (zh) * | 2022-02-09 | 2023-06-16 | 中国科学技术大学 | 用于预防和/或治疗代谢类疾病的益生菌组合物及其应用 |
| CN115281345A (zh) * | 2022-04-06 | 2022-11-04 | 金华银河生物科技有限公司 | 一种复合益生菌组合物联合二甲基胍治疗ⅱ型糖尿病的用途 |
| WO2023219460A1 (ko) * | 2022-05-12 | 2023-11-16 | 주식회사 지아이바이옴 | 락토바실러스 퍼멘텀 균주 및 대사조절제를 포함하는 병용 요법을 이용한 대사질환 예방 또는 치료용 조성물 |
| CN115948273B (zh) * | 2022-06-21 | 2023-07-18 | 合肥瀚微生物科技有限公司 | 治疗糖尿病及相关病症的两歧双歧杆菌 |
| CN115137757A (zh) * | 2022-07-29 | 2022-10-04 | 承葛健康科技(广东)有限公司 | 一种辅助降血糖的益生菌组合物 |
| WO2024134035A1 (fr) * | 2022-12-22 | 2024-06-27 | Sorbonne Universite | Composition et utilisation de turicimonas muris pour le traitement de maladies métaboliques |
| CN117487692B (zh) * | 2023-10-08 | 2025-04-15 | 卡士酸奶(苏州)有限公司 | 一株缓解糖尿病症状的格氏乳杆菌及其应用 |
| CN117187145B (zh) * | 2023-10-20 | 2024-07-16 | 深圳保时健生物工程有限公司 | 一株具有降脂、降血糖和减重功能的嗜酸乳杆菌goldgut-la100及其应用 |
| CN117838737A (zh) * | 2023-12-21 | 2024-04-09 | 汤臣倍健股份有限公司 | 一种短双歧杆菌207-1及其在调节脂代谢方向的应用 |
| CN119286727B (zh) * | 2024-11-28 | 2025-02-28 | 山东环亿生物科技有限公司 | 一种动物双歧杆菌动物乳亚种9360-2及其在预防和/或治疗心脑血管疾病中的应用 |
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| US2002003A (en) | 1930-09-20 | 1935-05-21 | Ig Farbenindustrie Ag | Production of acetylene and carbon black |
| JP2779963B2 (ja) * | 1989-02-09 | 1998-07-23 | 株式会社林原生物化学研究所 | ビフィズス菌増殖促進剤 |
| SE510753C2 (sv) * | 1997-08-05 | 1999-06-21 | Probi Ab | Användning av en stam av Lactobacillus för tillverkning av ett läkemedel för reduktion av fibrinogenhalten i blod |
| US6811786B1 (en) * | 1999-04-01 | 2004-11-02 | Ganeden Biotech, Inc. | Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions |
| JP4580542B2 (ja) * | 2000-05-17 | 2010-11-17 | 株式會社バイオニア | 肥満又は糖尿病治療用微生物及びその微生物を含む医薬組成物 |
| SE0004124D0 (sv) | 2000-11-10 | 2000-11-10 | Probi Ab | New use |
| US20030092163A1 (en) * | 2001-07-26 | 2003-05-15 | Collins John Kevin | Probiotic bifidobacterium strains |
| US6953574B2 (en) * | 2002-06-21 | 2005-10-11 | Technology Commercialization, Inc. | Method for producing a fermented hydrolyzed medium containing microorganisms |
| KR100527103B1 (ko) * | 2003-02-04 | 2005-11-09 | 최현우 | 지질대사개선효능을 갖는 미생물을 함유한 성인병 예방 및치료용 조성물 및 이의 용도 |
| PL2805625T5 (pl) * | 2005-02-28 | 2023-03-13 | N.V. Nutricia | Kompozycja odżywcza z prebiotykami i probiotykami |
| SE529185C2 (sv) * | 2005-10-07 | 2007-05-22 | Arla Foods Amba | Användning av probiotiska bakterier för tillverkning av livsmedel eller läkemedel för förhindrande av övervikt |
| JP2009536016A (ja) * | 2006-01-20 | 2009-10-08 | インエル ビョルク, | アミノ酸を含む食品組成物 |
| DK2046943T3 (da) | 2006-08-04 | 2013-09-23 | Bioneer Corp | Mælkesyrebakterie isoleret fra modermælk med probiotisk aktivitet og inhibitorisk aktivitet over for stigning i legemsvægt |
| CN101310606A (zh) * | 2007-05-24 | 2008-11-26 | 大连森佰澳科技有限公司 | 含有双歧杆菌功能信号分子和益生元的液体奶制品 |
| EP2011506A1 (en) | 2007-07-05 | 2009-01-07 | Nestec S.A. | Supplementation of maternal diet |
| EP2022502A1 (en) | 2007-08-10 | 2009-02-11 | Nestec S.A. | Lactobacillus rhamnosus and weight control |
| EP2030623A1 (en) | 2007-08-17 | 2009-03-04 | Nestec S.A. | Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria |
| US20110189149A1 (en) * | 2008-06-20 | 2011-08-04 | Remy Burcelin | New Uses of Lactic Acid Bacteria and Bifidobacteria |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN104784694A (zh) | 2015-07-22 |
| EP2808024A1 (en) | 2014-12-03 |
| CN104770739A (zh) | 2015-07-15 |
| CN104784219A (zh) | 2015-07-22 |
| US20120107291A1 (en) | 2012-05-03 |
| BRPI1014081A2 (pt) | 2016-04-19 |
| US20250041358A1 (en) | 2025-02-06 |
| PL3181134T3 (pl) | 2020-04-30 |
| US20230248786A1 (en) | 2023-08-10 |
| CN102458415B (zh) | 2015-05-20 |
| ES2729765T3 (es) | 2019-11-06 |
| ES2702977T3 (es) | 2019-03-06 |
| CN104784220A (zh) | 2015-07-22 |
| EP3181134B1 (en) | 2019-10-30 |
| US20200316144A1 (en) | 2020-10-08 |
| EP2442814B1 (en) | 2018-09-26 |
| DK3181134T3 (da) | 2020-01-20 |
| ES2763137T3 (es) | 2020-05-27 |
| WO2010146568A2 (en) | 2010-12-23 |
| CN102458415A (zh) | 2012-05-16 |
| PL2808024T3 (pl) | 2019-09-30 |
| EP3181134A1 (en) | 2017-06-21 |
| US20180021391A1 (en) | 2018-01-25 |
| DK2808024T3 (da) | 2019-06-11 |
| EP2808024B1 (en) | 2019-04-24 |
| WO2010146568A3 (en) | 2011-05-05 |
| US20140348796A1 (en) | 2014-11-27 |
| US20190307815A1 (en) | 2019-10-10 |
| US20210322491A1 (en) | 2021-10-21 |
| EP2442814A2 (en) | 2012-04-25 |
| DK2442814T3 (en) | 2019-01-14 |
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