[go: up one dir, main page]

PE20070114A1 - Inhibidor de tubulina y proceso para su preparacion - Google Patents

Inhibidor de tubulina y proceso para su preparacion

Info

Publication number
PE20070114A1
PE20070114A1 PE2006000657A PE2006000657A PE20070114A1 PE 20070114 A1 PE20070114 A1 PE 20070114A1 PE 2006000657 A PE2006000657 A PE 2006000657A PE 2006000657 A PE2006000657 A PE 2006000657A PE 20070114 A1 PE20070114 A1 PE 20070114A1
Authority
PE
Peru
Prior art keywords
trifluoro
pirazin
react
phenyl
give
Prior art date
Application number
PE2006000657A
Other languages
English (en)
Spanish (es)
Inventor
David Michael Blum
Yanzhong Wu
Timothy John Doyle
Jay Thomas Afragola
Jean Schmid
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20070114(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20070114A1 publication Critical patent/PE20070114A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PE2006000657A 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion PE20070114A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US80278106P 2006-05-24 2006-05-24

Publications (1)

Publication Number Publication Date
PE20070114A1 true PE20070114A1 (es) 2007-02-03

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000657A PE20070114A1 (es) 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion

Country Status (12)

Country Link
EP (1) EP1891052A1 (fr)
JP (1) JP2008543838A (fr)
AR (1) AR054392A1 (fr)
AU (1) AU2006259663A1 (fr)
BR (1) BRPI0612145A2 (fr)
CA (1) CA2610416A1 (fr)
GT (1) GT200600257A (fr)
MX (1) MX2007015718A (fr)
PE (1) PE20070114A1 (fr)
SV (1) SV2007002573A (fr)
TW (1) TW200716613A (fr)
WO (1) WO2006138180A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057805A1 (fr) 2009-11-12 2011-05-19 R&D Biopharmaceuticals Gmbh Inhibiteurs de la tubuline
US9649317B2 (en) * 2012-09-19 2017-05-16 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2017181974A1 (fr) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 Composé hétérocyclique à cinq chaînons, procédé de préparation correspondant, composition pharmaceutique et utilisation
US11623927B2 (en) 2018-03-02 2023-04-11 The Trustees Of The University Of Pennsylvania Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE432077T1 (de) * 2003-09-24 2009-06-15 Wyeth Corp 5-arylpyrimidine als anti-krebs-mittel
WO2005030775A1 (fr) * 2003-09-24 2005-04-07 Wyeth Holdings Corporation 6-[(substitutees)phenyl]triazolopyrimidines utilisees en tant qu'agent anticancereux

Also Published As

Publication number Publication date
CA2610416A1 (fr) 2006-12-28
EP1891052A1 (fr) 2008-02-27
TW200716613A (en) 2007-05-01
BRPI0612145A2 (pt) 2010-10-19
AU2006259663A1 (en) 2006-12-28
JP2008543838A (ja) 2008-12-04
SV2007002573A (es) 2007-01-03
AR054392A1 (es) 2007-06-20
GT200600257A (es) 2007-02-14
WO2006138180A1 (fr) 2006-12-28
MX2007015718A (es) 2008-02-21

Similar Documents

Publication Publication Date Title
PE20171102A1 (es) Procesos para preparar inhibidores de jak y compuestos intermediarios relacionados
AR061924A1 (es) Proceso para elaborar 2- amino -5 - halobenzamidas 3- sustituidas
CO6220910A2 (es) Proceso para la producir compuestos pesticidas de benzamidas
PE20071238A1 (es) Proceso para la preparacion de heterociclos hidroxi substituidos
AR077924A1 (es) Procesos para preparar pemetrexed
PE20230156A1 (es) Sal de acido clorhidrico de (r)-4-(3-((s)-1-(4-amino-3-metil-1h pirazolo[3,4-d]pirimidin-1-il)etil)-5-cloro-2-etoxi-6-fluorofenil)pirrolidin-2-ona
RU2013119617A (ru) Способ получения 2-амино-n-(2, 2, 2-трифторэтил)ацетамида
PE20120424A1 (es) Compuestos de quinazolina sustituidos
RU2012156217A (ru) СПОСОБ ПОЛУЧЕНИЯ 5-ЗАМЕЩЕННЫХ-8-АЛКОКСИ[1,2,4]ТРИАЗОЛО[1,5-c]ПИРИМИДИН-2-АМИНОВ
EA201891769A1 (ru) СПОСОБ ПОЛУЧЕНИЯ СОЕДИНЕНИЯ ПИРРОЛО[3,2-d]ПИРИМИДИНА И ПРОМЕЖУТОЧНЫХ СОЕДИНЕНИЙ
CL2023000228A1 (es) Procesos para preparar derivados de 3-(2-pirimidinil) pirazoles
PE20070114A1 (es) Inhibidor de tubulina y proceso para su preparacion
GB0508717D0 (en) Chemical compounds
AR081399A1 (es) Proceso para preparar un compuesto de pirimidinona, compuestos intermediarios en dicho proceso y procesos para repararlos.
MX2019000138A (es) Procesos novedosos para preparacion de estimuladores de guanilato ciclasa soluble.
JP2019525913A5 (fr)
DE602006013136D1 (de) Ermediate
TW200745090A (en) Chemical compounds
Ma et al. Unsymmetric monothiooxalamides from S8, bromodifluoro reagents and anilines: Synthesis and applications
AR066430A1 (es) Proceso para preparar inhibidores de aromatasa y forma cristalina de exemestano
AR092563A1 (es) PROCESO PARA LA PREPARACION DE 2-AMINO-5,8-DIMETOXI[1,2,4]TRIAZOL[1,5-c]PIRIMIDINA A PARTIR DE 4-CLORO-2,5-DIMETOXIPIRIMIDINA
EA200600542A1 (ru) Способ для производства thip
AR058210A1 (es) Procedimiento para preparar 5-amino-3h-tiazolo[4,5-d]pirimidin-2-ona, un intermediario util para la preparacion de ciertos nucleosidos de tiazolo[4,5-d]pirimidina que actuan como inmunomoduladores.
ATE465999T1 (de) Verfahren zur herstellung substituierter pyrimidine
ATE443053T1 (de) Als inhibitoren von erbb-tyrosinkinase verwendete chinazoleinderivate

Legal Events

Date Code Title Description
FC Refusal