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ES2167592T3 - Preparaciones medicamentosas que contienen un enantiomero de bromuro de ipratropio con duracion de la accion prolongada. - Google Patents

Preparaciones medicamentosas que contienen un enantiomero de bromuro de ipratropio con duracion de la accion prolongada.

Info

Publication number
ES2167592T3
ES2167592T3 ES96927638T ES96927638T ES2167592T3 ES 2167592 T3 ES2167592 T3 ES 2167592T3 ES 96927638 T ES96927638 T ES 96927638T ES 96927638 T ES96927638 T ES 96927638T ES 2167592 T3 ES2167592 T3 ES 2167592T3
Authority
ES
Spain
Prior art keywords
ipratropio
duration
preparations containing
prolonged action
drug preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96927638T
Other languages
English (en)
Inventor
Rolf Banholzer
Richard Reichl
Bernd Disse
Georg Speck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7768353&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2167592(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Application granted granted Critical
Publication of ES2167592T3 publication Critical patent/ES2167592T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION TRATA DEL USO DE SALES DE L (-) ENANATIOMEROS DE (ENDO,SIN) (-) 3 (3 HIDROXI 1 OXO 2 FENILPROPOXI) 8 METIL 8 (METILETIL) 8 AZONIABICICLO[3.2.1] OCTANOS COMO SUSTANCIAS ACTIVAS PARA MEDICAMENTOS ADMINISTRADOS POR INHALACION INDICADOS EN LOS TRATAMIENTOS TERAPEUTICOS DE LAS VIAS RESPIRATORIAS. ESTAS SALES SON APTAS PARA ESTOS TRATAMIENTOS GRACIAS A SU SORPRENDENTE EFECTO INTENSO Y DURADERO.
ES96927638T 1995-08-01 1996-07-31 Preparaciones medicamentosas que contienen un enantiomero de bromuro de ipratropio con duracion de la accion prolongada. Expired - Lifetime ES2167592T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19528145A DE19528145A1 (de) 1995-08-01 1995-08-01 Neue Arzneimittel und ihre Verwendung

Publications (1)

Publication Number Publication Date
ES2167592T3 true ES2167592T3 (es) 2002-05-16

Family

ID=7768353

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96927638T Expired - Lifetime ES2167592T3 (es) 1995-08-01 1996-07-31 Preparaciones medicamentosas que contienen un enantiomero de bromuro de ipratropio con duracion de la accion prolongada.

Country Status (36)

Country Link
US (1) US6299861B1 (es)
EP (1) EP0843676B1 (es)
JP (1) JPH11510150A (es)
KR (1) KR100445016B1 (es)
CN (1) CN1120841C (es)
AR (1) AR004179A1 (es)
AT (1) ATE208390T1 (es)
AU (1) AU6739796A (es)
BG (1) BG63780B1 (es)
BR (1) BR9609951A (es)
CA (1) CA2226934C (es)
CO (1) CO4750836A1 (es)
CZ (1) CZ291998B6 (es)
DE (2) DE19528145A1 (es)
DK (1) DK0843676T3 (es)
EE (1) EE04614B1 (es)
ES (1) ES2167592T3 (es)
HR (1) HRP960365B1 (es)
HU (1) HU228056B1 (es)
IL (1) IL118986A (es)
MX (1) MX9800864A (es)
MY (1) MY115201A (es)
NO (1) NO317561B1 (es)
NZ (1) NZ315645A (es)
PL (1) PL183789B1 (es)
PT (1) PT843676E (es)
RO (1) RO120260B1 (es)
RU (1) RU2171258C2 (es)
SI (1) SI0843676T1 (es)
SK (1) SK283260B6 (es)
TR (1) TR199800121T1 (es)
TW (1) TW449597B (es)
UA (1) UA55391C2 (es)
WO (1) WO1997005136A1 (es)
YU (1) YU49479B (es)
ZA (1) ZA966494B (es)

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SI1305329T2 (sl) 2000-08-05 2015-07-31 Glaxo Group Limited S-fluorometil ester 6alfa,9alfa-difluoro-17alfa-(2-furanilkarboksil)oksi-11beta-hidroksi- 16alfa-metil-3-okso-androst-1,4-dien-17-karbotiojske kisline kot protivnetno sredstvo
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
US6455028B1 (en) * 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
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CA2445839A1 (en) 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20050043343A1 (en) * 2003-07-28 2005-02-24 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050101545A1 (en) * 2003-07-31 2005-05-12 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050038004A1 (en) * 2003-07-31 2005-02-17 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
SI1765404T1 (sl) * 2004-05-31 2009-04-30 Almirall Lab Kombinacije, ki obsegajo antimuskarinska sredstva in beta-adrenergične agoniste
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende
WO2006114379A1 (de) * 2005-04-23 2006-11-02 Boehringer Ingelheim International Gmbh Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid
US20060239935A1 (en) * 2005-04-23 2006-10-26 Boehringer Ingelheim International Gmbh Compositions for inhalation
RU2296761C2 (ru) * 2005-04-28 2007-04-10 Федеральное государственное унитирное предприятие Государственный научно-исследовательский институт органической химии и технологии (ФГУП ГосНИИОХТ) Бромид 1-гексадецил-r-(-)-3-окси-1-азониабицикло[2.2.2]октана - иммуномодулятор с противоопухолевыми, бактериостатическими и антиагрегантными свойствами и способ его получения
NZ564697A (en) * 2005-06-15 2010-04-30 Boehringer Ingelheim Int Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
RU2321589C2 (ru) * 2005-08-19 2008-04-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт органической химии и технологии "(ФГУП "ГосНИИОХТ" ) Способ получения бромида 1-гексадецил-r(-)-3-окси-1-азониабицикло[2.2.2]октана-иммуномодулятора с противоопухолевыми, бактериостатическими и антиагрегантными свойствами
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CN111751454B (zh) * 2019-03-29 2023-12-08 天津药业研究院股份有限公司 一种异丙托溴铵中间体i的含量和有关物质的检测方法
CN110361494B (zh) * 2019-06-26 2023-08-15 四川普锐特药业有限公司 异丙托溴铵气雾剂中杂质g的检测方法

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Also Published As

Publication number Publication date
NO980424D0 (no) 1998-01-30
BR9609951A (pt) 1999-02-02
MY115201A (en) 2003-04-30
PL183789B1 (pl) 2002-07-31
HK1013597A1 (en) 1999-09-03
TW449597B (en) 2001-08-11
AU6739796A (en) 1997-02-26
YU44596A (sh) 1998-12-23
KR19990035997A (ko) 1999-05-25
UA55391C2 (uk) 2003-04-15
EP0843676A1 (de) 1998-05-27
ATE208390T1 (de) 2001-11-15
NZ315645A (en) 1999-11-29
MX9800864A (es) 1998-04-30
PT843676E (pt) 2002-04-29
AR004179A1 (es) 1998-11-04
EE04614B1 (et) 2006-04-17
EE9800028A (et) 1998-08-17
TR199800121T1 (xx) 1998-04-21
CZ225396A3 (cs) 1998-03-18
DE19528145A1 (de) 1997-02-06
EP0843676B1 (de) 2001-11-07
JPH11510150A (ja) 1999-09-07
NO980424L (no) 1998-01-30
SK283260B6 (sk) 2003-04-01
CA2226934A1 (en) 1997-02-13
SK11298A3 (en) 1998-07-08
HRP960365B1 (en) 2002-04-30
HU9602104D0 (en) 1996-09-30
RU2171258C2 (ru) 2001-07-27
WO1997005136A1 (de) 1997-02-13
CZ291998B6 (cs) 2003-07-16
DK0843676T3 (da) 2001-12-27
ZA966494B (en) 1997-02-03
CN1120841C (zh) 2003-09-10
HUP9602104A2 (en) 1997-04-28
SI0843676T1 (en) 2002-06-30
IL118986A (en) 1998-12-06
CO4750836A1 (es) 1999-03-31
HUP9602104A3 (en) 2000-03-28
BG63780B1 (bg) 2002-12-29
HU228056B1 (en) 2012-09-28
US6299861B1 (en) 2001-10-09
KR100445016B1 (ko) 2004-11-08
HK1010879A1 (en) 1999-07-02
PL324804A1 (en) 1998-06-22
BG102202A (en) 1998-09-30
CA2226934C (en) 2007-05-01
NO317561B1 (no) 2004-11-15
DE59608156D1 (de) 2001-12-13
IL118986A0 (en) 1996-10-31
HRP960365A2 (en) 1998-02-28
YU49479B (sh) 2006-05-25
CN1191535A (zh) 1998-08-26
RO120260B1 (ro) 2005-11-30

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