EG20530A - Process for preparing of phenoxyphenyl cyclopentenyl hydroxyureas - Google Patents
Process for preparing of phenoxyphenyl cyclopentenyl hydroxyureasInfo
- Publication number
- EG20530A EG20530A EG50694A EG50694A EG20530A EG 20530 A EG20530 A EG 20530A EG 50694 A EG50694 A EG 50694A EG 50694 A EG50694 A EG 50694A EG 20530 A EG20530 A EG 20530A
- Authority
- EG
- Egypt
- Prior art keywords
- pct
- date
- hydroxyureas
- phenoxyphenyl
- cyclopentenyl
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 phenoxyphenyl cyclopentenyl Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 206010027654 Allergic conditions Diseases 0.000 abstract 1
- 239000000867 Lipoxygenase Inhibitor Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyurethanes Or Polyureas (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20545393 | 1993-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG20530A true EG20530A (en) | 1999-07-31 |
Family
ID=16507136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EG50694A EG20530A (en) | 1993-08-19 | 1994-08-17 | Process for preparing of phenoxyphenyl cyclopentenyl hydroxyureas |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5792882A (fr) |
| EP (1) | EP0720598B1 (fr) |
| JP (1) | JP2794343B2 (fr) |
| KR (1) | KR0170623B1 (fr) |
| CN (1) | CN1077568C (fr) |
| AT (1) | ATE171939T1 (fr) |
| AU (1) | AU674776B2 (fr) |
| BR (1) | BR9407314A (fr) |
| CA (1) | CA2169066C (fr) |
| CO (1) | CO4230229A1 (fr) |
| CZ (1) | CZ288358B6 (fr) |
| DE (1) | DE69413831T2 (fr) |
| DK (1) | DK0720598T3 (fr) |
| EC (1) | ECSP941144A (fr) |
| EG (1) | EG20530A (fr) |
| ES (1) | ES2121218T3 (fr) |
| FI (1) | FI114466B (fr) |
| IL (1) | IL110628A (fr) |
| MY (1) | MY111140A (fr) |
| NO (1) | NO305595B1 (fr) |
| NZ (1) | NZ269849A (fr) |
| PE (1) | PE57194A1 (fr) |
| PL (1) | PL176223B1 (fr) |
| RU (1) | RU2125987C1 (fr) |
| TW (2) | TW448144B (fr) |
| WO (1) | WO1995005360A1 (fr) |
| ZA (1) | ZA946253B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ372096A3 (cs) * | 1994-06-27 | 1998-04-15 | Cytomed Inc. | Sloučeniny a metody léčby kardiovaskulárních, dýchacích a imunitních potíží |
| ES2135066T3 (es) * | 1994-11-10 | 1999-10-16 | Pfizer | Ariloxicicloalquenil- y ariloxiiminocicloalquenilhidroxiureas como inhibidores de la 5-lipoxigenasa. |
| WO1996016054A1 (fr) * | 1994-11-18 | 1996-05-30 | Pfizer Pharmaceuticals Inc. | Cycloalcenyl-n-hydroxyurees |
| EP1741424B1 (fr) | 1997-08-11 | 2018-10-03 | Pfizer Products Inc. | Dispersions solides pharmaceutiques à biodisponibilité accrue |
| US6121323A (en) * | 1997-12-03 | 2000-09-19 | 3M Innovative Properties Company | Bishydroxyureas |
| EP1841729B1 (fr) * | 2004-12-02 | 2011-01-12 | Amorepacific Corporation | Derives de 2-cyclopentene-1-one oxime inhibant la production de tnf-alpha |
| WO2009072807A2 (fr) * | 2007-12-03 | 2009-06-11 | Amorepacific Corporation | Prévention ou traitement de troubles associés au métabolisme des graisses maladies grâce à une composition pharmaceutique contenant des dérivés de 2.cyclopentène-1-one oxime |
| MY160737A (en) | 2009-04-03 | 2017-03-15 | Hoffmann La Roche | Propane-i-sulfonic acid {3- [5-(4-chloro-phenyl) -1h -pyrrolo [2, 3-b] pyridine-3-carbonyl] -2,4 difluoro-phenyl} - amide compositions and uses thereof |
| US8512464B2 (en) * | 2009-12-02 | 2013-08-20 | 3M Innovative Properties Company | Functionalized zirconia nanoparticles and high index films made therefrom |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ222168A (en) * | 1986-10-20 | 1991-05-28 | Oncogene Science Inc | Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions |
| US5026729A (en) * | 1987-02-10 | 1991-06-25 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
| PT93049A (pt) * | 1989-02-03 | 1990-08-31 | Wellcome Found | Processo para a preparacao de compostos de aril-hidroxi-ureia possuindo actividade anti-inflamatoria e de composicoes farmaceuticas que os contem |
| US5120752A (en) * | 1989-12-28 | 1992-06-09 | Abbott Laboratories | Cyclopropyl derivative lipoxygenase inhibitors |
| US5037853A (en) * | 1989-12-28 | 1991-08-06 | Abbott Laboratories | Cyclopropyl derivative lipoxygenase inhibitors |
| GB9025514D0 (en) * | 1990-11-23 | 1991-01-09 | Wellcome Found | Anti-inflammatory compounds |
| JP3007138B2 (ja) * | 1990-11-27 | 2000-02-07 | ファイザー製薬株式会社 | 新規なヒドロキサム酸とn―ヒドロキシ尿素誘導体およびそれらの組成物 |
| JPH06256285A (ja) * | 1990-12-11 | 1994-09-13 | Pfizer Pharmaceut Co Ltd | ヒドロキサム酸誘導体およびその用途 |
| US5130485A (en) * | 1991-04-23 | 1992-07-14 | Eli Lilly And Company | N-hydroxy-N-(3-(2-substituted phenyl)prop-2-enyl)ureas and thioureas useful as 5-lipoxygenase inhibiting agents |
| US5149097A (en) * | 1991-05-01 | 1992-09-22 | Tonello John H | Crossword puzzle aid |
| JPH05163229A (ja) * | 1991-12-13 | 1993-06-29 | Pfizer Pharmaceut Co Ltd | 新規なシクロプロピル誘導体 |
| JPH05294921A (ja) * | 1992-04-17 | 1993-11-09 | Pfizer Pharmaceut Co Ltd | 新規なフェニル置換シクロアルキル尿素誘導体および組成物 |
-
1994
- 1994-07-25 TW TW089116268A patent/TW448144B/zh active
- 1994-07-25 TW TW083106784A patent/TW418089B/zh not_active IP Right Cessation
- 1994-08-11 IL IL11062894A patent/IL110628A/en not_active IP Right Cessation
- 1994-08-11 PE PE1994248312A patent/PE57194A1/es not_active Application Discontinuation
- 1994-08-15 ES ES94922374T patent/ES2121218T3/es not_active Expired - Lifetime
- 1994-08-15 AT AT94922374T patent/ATE171939T1/de not_active IP Right Cessation
- 1994-08-15 US US08/591,634 patent/US5792882A/en not_active Expired - Fee Related
- 1994-08-15 CA CA002169066A patent/CA2169066C/fr not_active Expired - Fee Related
- 1994-08-15 CN CN94193117A patent/CN1077568C/zh not_active Expired - Fee Related
- 1994-08-15 WO PCT/JP1994/001349 patent/WO1995005360A1/fr not_active Ceased
- 1994-08-15 KR KR1019960700828A patent/KR0170623B1/ko not_active Expired - Fee Related
- 1994-08-15 RU RU96105400A patent/RU2125987C1/ru not_active IP Right Cessation
- 1994-08-15 AU AU73509/94A patent/AU674776B2/en not_active Ceased
- 1994-08-15 CZ CZ1996483A patent/CZ288358B6/cs not_active IP Right Cessation
- 1994-08-15 DK DK94922374T patent/DK0720598T3/da active
- 1994-08-15 BR BR9407314A patent/BR9407314A/pt not_active Application Discontinuation
- 1994-08-15 NZ NZ269849A patent/NZ269849A/en unknown
- 1994-08-15 EP EP94922374A patent/EP0720598B1/fr not_active Expired - Lifetime
- 1994-08-15 JP JP7506862A patent/JP2794343B2/ja not_active Expired - Fee Related
- 1994-08-15 MY MYPI94002132A patent/MY111140A/en unknown
- 1994-08-15 DE DE69413831T patent/DE69413831T2/de not_active Expired - Fee Related
- 1994-08-17 EC EC1994001144A patent/ECSP941144A/es unknown
- 1994-08-17 EG EG50694A patent/EG20530A/xx active
- 1994-08-18 FI FI943799A patent/FI114466B/fi not_active IP Right Cessation
- 1994-08-18 ZA ZA946253A patent/ZA946253B/xx unknown
- 1994-08-19 CO CO94036772A patent/CO4230229A1/es unknown
-
1996
- 1996-02-16 NO NO960631A patent/NO305595B1/no not_active IP Right Cessation
- 1996-02-16 PL PL94313037A patent/PL176223B1/pl unknown
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