DK3453387T3 - Doseringsplan til en s1p-receptoragonist - Google Patents

Doseringsplan til en s1p-receptoragonist Download PDF

Info

Publication number: DK3453387T3
Authority: DK; Denmark
Prior art keywords: receptor agonist; dosage plan; dosage; plan; agonist
Prior art date: 2008-12-22

Application number

DK18201062.9T

Other languages

English (en)

Inventor

Robert Schmouder

Thomas Dumortier

Olivier David

Michael Looby

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-22

Filing date

2009-12-21

Publication date

2020-08-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3453387(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-12-21 Application filed by Novartis Ag filed Critical Novartis Ag

2020-08-10 Application granted granted Critical

2020-08-10 Publication of DK3453387T3 publication Critical patent/DK3453387T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK18201062.9T 2008-12-22 2009-12-21 Doseringsplan til en s1p-receptoragonist DK3453387T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US13967208P	2008-12-22	2008-12-22
US21853009P	2009-06-19	2009-06-19
US24671509P	2009-09-29	2009-09-29
EP16182876.9A EP3120844A1 (en)	2008-12-22	2009-12-21	Dosage regimen for a s1p receptor agonist

Publications (1)

Publication Number	Publication Date
DK3453387T3 true DK3453387T3 (da)	2020-08-10

Family

ID=41667217

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
DK18201062.9T DK3453387T3 (da)	2008-12-22	2009-12-21	Doseringsplan til en s1p-receptoragonist
DK18179301.9T DK3409274T3 (da)	2008-12-22	2009-12-21	Doseringsskema for en s1p-receptoragonist
DK22187007.4T DK4098256T5 (da)	2008-12-22	2009-12-21	Doseringsregime for en s1p-receptoragonist
DK09797234.3T DK2379067T3 (da)	2008-12-22	2009-12-21	Doseringsregimen for fingolimod til behandling af multipel sklerose

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
DK18179301.9T DK3409274T3 (da)	2008-12-22	2009-12-21	Doseringsskema for en s1p-receptoragonist
DK22187007.4T DK4098256T5 (da)	2008-12-22	2009-12-21	Doseringsregime for en s1p-receptoragonist
DK09797234.3T DK2379067T3 (da)	2008-12-22	2009-12-21	Doseringsregimen for fingolimod til behandling af multipel sklerose

Country Status (43)

Country	Link
US (12)	US20110257133A1 (da)
EP (7)	EP3409274B1 (da)
JP (7)	JP2012513401A (da)
KR (1)	KR101347919B1 (da)
CN (1)	CN102264359A (da)
AR (1)	AR074826A1 (da)
AU (1)	AU2009330176C9 (da)
BR (1)	BRPI0923500A2 (da)
CA (1)	CA2747802C (da)
CL (2)	CL2011001529A1 (da)
CO (1)	CO6390117A2 (da)
CR (1)	CR20110274A (da)
CU (1)	CU20110136A7 (da)
CY (4)	CY1116990T1 (da)
DK (4)	DK3453387T3 (da)
EA (1)	EA201100978A1 (da)
EC (1)	ECSP11011222A (da)
ES (4)	ES2760607T3 (da)
FI (2)	FI4098256T3 (da)
FR (2)	FR20C1060I1 (da)
HN (1)	HN2011001759A (da)
HR (4)	HRP20151190T1 (da)
HU (6)	HUE026869T2 (da)
IL (3)	IL213170A0 (da)
LT (5)	LT3453387T (da)
LU (1)	LUC00183I2 (da)
MA (1)	MA32981B1 (da)
ME (2)	ME03802B (da)
MX (3)	MX2011006623A (da)
NO (1)	NO2020038I1 (da)
NZ (1)	NZ593065A (da)
PE (1)	PE20120337A1 (da)
PL (4)	PL3453387T3 (da)
PT (4)	PT2379067E (da)
RS (3)	RS66784B9 (da)
SG (1)	SG171404A1 (da)
SI (4)	SI3409274T1 (da)
SM (2)	SMT202000054T1 (da)
TN (1)	TN2011000272A1 (da)
TW (1)	TW201028143A (da)
UY (1)	UY32352A (da)
WO (1)	WO2010075239A1 (da)
ZA (2)	ZA201103863B (da)

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BRPI0909625B1 (pt)	2008-03-17	2021-09-08	Actelion Pharmaceuticals Ltd	Agonista seletivo do receptor s1p1 para o uso como um medicamento, uso de um agonista seletivo do receptor s1p1 e kit contendo diferentes unidades de medicação de um agonista seletivo do receptor s1p1
SI3409274T1 (sl)	2008-12-22	2020-03-31	Novartis Ag	Režim odmerjanja za S1P receptor agonist
AU2010101513B4 (en)	2009-09-29	2016-05-05	Novartis Ag	Dosage regimen of an S1P receptor modulator
US20110124605A1 (en) *	2009-11-20	2011-05-26	Shreeram Aradhye	Use of an S1P Receptor Agonist
SG182610A1 (en)	2010-01-27	2012-08-30	Arena Pharm Inc	Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
AU2011249789B2 (en) *	2010-05-06	2015-03-19	Novartis Ag	Dosage regimen of diaryl sulfide derivatives
EP2455080A1 (en) *	2010-11-23	2012-05-23	Almirall, S.A.	S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr)	2010-12-13	2013-12-27	Centre Nat Rech Scient	Inhibiteurs des infections a vih et leurs utilisations
UA114283C2 (uk)	2011-01-07	2017-05-25	Новартіс Аг	Композиції імуносупресантів
WO2012112933A1 (en)	2011-02-18	2012-08-23	The Scripps Research Institute	Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
JO3177B1 (ar)	2011-04-01	2018-03-08	Novartis Ag	تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
US9592268B2 (en)	2011-05-23	2017-03-14	Cornell University	Endothelium protective materials and methods of use
TW201320994A (zh) *	2011-10-11	2013-06-01	Novartis Ag	投藥療程
HUE050733T2 (hu)	2012-08-17	2021-01-28	Actelion Pharmaceuticals Ltd	Eljárás (2Z,5Z)-5-(3-klór-4-((R)-2,3-dihidroxipropoxi)benzilidén)-2-(pro-pilimino)-3-(O-tolil)tiazolidin-4-on elõállítására és ezen eljárásban alkalmazott köztitermék
AU2014225534A1 (en) *	2013-03-06	2015-09-24	Acorda Therapeutics, Inc.	Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure
US10675254B2 (en)	2013-10-11	2020-06-09	Teikoku Seiyaku Co., Ltd.	Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
EP3054933A4 (en)	2013-10-11	2017-03-15	Teikoku Pharma USA, Inc.	Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same
JP6674903B2 (ja) *	2014-04-10	2020-04-01	ノバルティスアーゲー	Ｓ１ｐ調節剤即時放出投与レジメン
MA41139A (fr)	2014-12-11	2017-10-17	Actelion Pharmaceuticals Ltd	Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
AU2015359346B2 (en)	2014-12-11	2020-05-07	Laboratoires Juvise Pharmaceuticals	Dosing regimen for a selective S1P1 receptor agonist
US11007175B2 (en) *	2015-01-06	2021-05-18	Arena Pharmaceuticals, Inc.	Methods of treating conditions related to the S1P1 receptor
WO2016135644A1 (en)	2015-02-26	2016-09-01	Novartis Ag	Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
BR112017027656B1 (pt)	2015-06-22	2023-12-05	Arena Pharmaceuticals, Inc.	Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
CA3053418A1 (en)	2017-02-16	2018-08-23	Arena Pharmaceuticals, Inc.	Compounds and methods for treatment of primary biliary cholangitis
JP2020507610A (ja)	2017-02-16	2020-03-12	アリーナファーマシューティカルズ，インコーポレイテッド	腸管外症状を伴う炎症性腸疾患の治療のための化合物および方法
BR112020024762A2 (pt)	2018-06-06	2021-03-23	Arena Pharmaceuticals, Inc.	métodos de tratamento de condições relacionadas ao receptor s1p1
CA3156298A1 (en)	2019-10-31	2021-05-06	Laetitia POUZOL	Combination of a cxcr7 antagonist with an s1p1 receptor modulator
US11135197B2 (en)	2020-02-07	2021-10-05	Argentum Pharmaceuticals Llc	Dosage regimen of an S1P receptor modulator
WO2021158848A1 (en) *	2020-02-07	2021-08-12	Argentum Pharmaceuticals Llc	Dosage regimen of an s1p receptor agonist
US20230094545A1 (en) *	2020-02-28	2023-03-30	Akaal Pharma Pty Ltd	S1p receptor modulators
CN113332435B (zh) *	2021-06-18	2022-10-18	广州中医药大学(广州中医药研究院)	鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

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AU8533101A (en)	2000-08-31	2002-03-13	Merck & Co Inc	Phosphate derivatives as immunoregulatory agents
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BRPI0923213A2 (pt) *	2008-12-22	2016-01-26	Novaris Ag	regime de dosagem de um agonista do receptor para s1p.

2009
- 2009-12-21 SI SI200932015T patent/SI3409274T1/sl unknown
- 2009-12-21 EP EP18179301.9A patent/EP3409274B1/en not_active Revoked
- 2009-12-21 EP EP09797234.3A patent/EP2379067B1/en not_active Revoked
- 2009-12-21 ME MEP-2020-156A patent/ME03802B/me unknown
- 2009-12-21 PE PE2011001265A patent/PE20120337A1/es not_active Application Discontinuation
- 2009-12-21 SM SM20200054T patent/SMT202000054T1/it unknown
- 2009-12-21 HU HUE09797234A patent/HUE026869T2/en unknown
- 2009-12-21 ES ES18179301T patent/ES2760607T3/es active Active
- 2009-12-21 SG SG2011037629A patent/SG171404A1/en unknown
- 2009-12-21 UY UY0001032352A patent/UY32352A/es not_active Application Discontinuation
- 2009-12-21 HR HRP20151190TT patent/HRP20151190T1/hr unknown
- 2009-12-21 RS RS20250452A patent/RS66784B9/sr unknown
- 2009-12-21 MX MX2011006623A patent/MX2011006623A/es unknown
- 2009-12-21 LT LTEP18201062.9T patent/LT3453387T/lt unknown
- 2009-12-21 KR KR1020117017073A patent/KR101347919B1/ko active Active
- 2009-12-21 ES ES18201062T patent/ES2810823T3/es active Active
- 2009-12-21 SI SI200932211T patent/SI4098256T1/sl unknown
- 2009-12-21 PT PT97972343T patent/PT2379067E/pt unknown
- 2009-12-21 PL PL18201062T patent/PL3453387T3/pl unknown
- 2009-12-21 ES ES09797234.3T patent/ES2552823T3/es active Active
- 2009-12-21 EP EP18201062.9A patent/EP3453387B1/en active Active
- 2009-12-21 EA EA201100978A patent/EA201100978A1/ru unknown
- 2009-12-21 ES ES22187007T patent/ES3017254T3/es active Active
- 2009-12-21 CA CA2747802A patent/CA2747802C/en active Active
- 2009-12-21 LT LTEP18179301.9T patent/LT3409274T/lt unknown
- 2009-12-21 EP EP16182876.9A patent/EP3120844A1/en not_active Withdrawn
- 2009-12-21 SM SM20200441T patent/SMT202000441T1/it unknown
- 2009-12-21 LT LTEP22187007.4T patent/LT4098256T/lt unknown
- 2009-12-21 MX MX2018006099A patent/MX385959B/es unknown
- 2009-12-21 RS RS20200900A patent/RS60666B1/sr unknown
- 2009-12-21 PT PT181793019T patent/PT3409274T/pt unknown
- 2009-12-21 NZ NZ593065A patent/NZ593065A/xx not_active IP Right Cessation
- 2009-12-21 BR BRPI0923500-0A patent/BRPI0923500A2/pt not_active Application Discontinuation
- 2009-12-21 HU HUE22187007A patent/HUE071189T2/hu unknown
- 2009-12-21 FI FIEP22187007.4T patent/FI4098256T3/fi active
- 2009-12-21 US US13/141,552 patent/US20110257133A1/en not_active Abandoned
- 2009-12-21 SI SI200931311T patent/SI2379067T1/sl unknown
- 2009-12-21 EP EP15158251.7A patent/EP2907511A1/en not_active Withdrawn
- 2009-12-21 DK DK18201062.9T patent/DK3453387T3/da active
- 2009-12-21 US US12/642,892 patent/US20100160259A1/en not_active Abandoned
- 2009-12-21 DK DK18179301.9T patent/DK3409274T3/da active
- 2009-12-21 RS RS20191546A patent/RS59857B1/sr unknown
- 2009-12-21 MA MA34034A patent/MA32981B1/fr unknown
- 2009-12-21 PT PT182010629T patent/PT3453387T/pt unknown
- 2009-12-21 EP EP22187007.4A patent/EP4098256B9/en active Active
- 2009-12-21 HR HRP20250568TT patent/HRP20250568T1/hr unknown
- 2009-12-21 CN CN2009801518640A patent/CN102264359A/zh active Pending
- 2009-12-21 PT PT221870074T patent/PT4098256T/pt unknown
- 2009-12-21 DK DK22187007.4T patent/DK4098256T5/da active
- 2009-12-21 HU HUE18179301A patent/HUE048717T4/hu unknown
- 2009-12-21 AR ARP090105010A patent/AR074826A1/es not_active Application Discontinuation
- 2009-12-21 EP EP20160225.7A patent/EP3677260A1/en active Pending
- 2009-12-21 TW TW098143960A patent/TW201028143A/zh unknown
- 2009-12-21 ME MEP-2019-339A patent/ME03594B/me unknown
- 2009-12-21 PL PL18179301T patent/PL3409274T3/pl unknown
- 2009-12-21 JP JP2011542521A patent/JP2012513401A/ja not_active Withdrawn
- 2009-12-21 SI SI200932080T patent/SI3453387T1/sl unknown
- 2009-12-21 HU HUE18201062A patent/HUE052048T2/hu unknown
- 2009-12-21 AU AU2009330176A patent/AU2009330176C9/en not_active Withdrawn - After Issue
- 2009-12-21 WO PCT/US2009/068888 patent/WO2010075239A1/en not_active Ceased
- 2009-12-21 PL PL09797234T patent/PL2379067T3/pl unknown
- 2009-12-21 PL PL22187007.4T patent/PL4098256T3/pl unknown
- 2009-12-21 DK DK09797234.3T patent/DK2379067T3/da active
2011
- 2011-05-25 CR CR20110274A patent/CR20110274A/es not_active Application Discontinuation
- 2011-05-25 ZA ZA2011/03863A patent/ZA201103863B/en unknown
- 2011-05-26 IL IL213170A patent/IL213170A0/en unknown
- 2011-05-26 TN TN2011000272A patent/TN2011000272A1/fr unknown
- 2011-06-17 MX MX2021010759A patent/MX2021010759A/es unknown
- 2011-06-21 CL CL2011001529A patent/CL2011001529A1/es unknown
- 2011-06-22 HN HN2011001759A patent/HN2011001759A/es unknown
- 2011-06-22 EC EC2011011222A patent/ECSP11011222A/es unknown
- 2011-06-22 CU CU20110136A patent/CU20110136A7/es unknown
- 2011-06-23 CO CO11079290A patent/CO6390117A2/es not_active Application Discontinuation
2012
- 2012-08-06 ZA ZA2012/05942A patent/ZA201205942B/en unknown
2013
- 2013-05-31 CL CL2013001558A patent/CL2013001558A1/es unknown
- 2013-09-06 US US14/020,058 patent/US20140066657A1/en not_active Abandoned
2014
- 2014-01-31 US US14/169,660 patent/US20140148415A1/en not_active Abandoned
- 2014-04-10 JP JP2014080892A patent/JP2014144970A/ja not_active Withdrawn
2015
- 2015-10-14 JP JP2015202669A patent/JP2016135752A/ja not_active Withdrawn
- 2015-11-30 CY CY20151101084T patent/CY1116990T1/el unknown
- 2015-12-02 US US14/956,855 patent/US20160081949A1/en not_active Abandoned
2016
- 2016-05-23 US US15/161,778 patent/US20160263061A1/en not_active Abandoned
2017
- 2017-03-06 JP JP2017041331A patent/JP2017141238A/ja not_active Withdrawn
- 2017-03-21 US US15/465,091 patent/US20170189353A1/en not_active Abandoned
2018
- 2018-06-11 US US16/005,137 patent/US20180289638A1/en not_active Abandoned
- 2018-11-26 US US16/199,905 patent/US20190091180A1/en not_active Abandoned
2019
- 2019-05-22 JP JP2019095899A patent/JP7329965B2/ja active Active
- 2019-12-02 HR HRP20192175TT patent/HRP20192175T1/hr unknown
- 2019-12-03 CY CY20191101264T patent/CY1122812T1/el unknown
2020
- 2020-05-05 US US16/867,293 patent/US20200330407A1/en not_active Abandoned
- 2020-05-18 IL IL274756A patent/IL274756A/en unknown
- 2020-07-27 HR HRP20201167TT patent/HRP20201167T1/hr unknown
- 2020-08-03 CY CY20201100712T patent/CY1123255T1/el unknown
- 2020-11-17 LT LTPA2020005C patent/LTPA2020005I1/lt unknown
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2021
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2024
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2025
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ECSP11011222A (es)	2011-08-31
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EA201100978A1 (ru)	2012-01-30
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SI3453387T1 (sl)	2020-10-30

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LTC2379069I2 (lt)	2022-05-25	S1p receptoriaus agonisto dozavimas
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HRP20170246T1 (hr)	2017-04-07	Režim doziranja za selektivni agonist s1p1-receptora
DK2274032T3 (da)	2012-10-29	Anordning til medicinindgivelse
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BR112013002096A2 (pt)	2019-09-24	compostos de agonistas de receptor glp-1 possuindo regiões estabilizadas
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BRPI0915781A2 (pt)	2015-11-10	oxazolopiridimas como agonista do receptor edg-1
IL231945A0 (en)	2014-05-28	Funding dosing regimen for s1p receptor modulator or agonist
TH0901005765A (th)	2016-05-10	ข้อกำหนดขนาดใช้สำหรับตัวทำการของตัวรับ S1P (S1P Receptor Agonist)