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DK2052753T3 - Fremgangsmåde til fordampning af en forbindelse - Google Patents

Fremgangsmåde til fordampning af en forbindelse Download PDF

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Publication number
DK2052753T3
DK2052753T3 DK09002094.2T DK09002094T DK2052753T3 DK 2052753 T3 DK2052753 T3 DK 2052753T3 DK 09002094 T DK09002094 T DK 09002094T DK 2052753 T3 DK2052753 T3 DK 2052753T3
Authority
DK
Denmark
Prior art keywords
substrate
drug
combustible element
combustible
housing
Prior art date
Application number
DK09002094.2T
Other languages
English (en)
Inventor
Ron L Hale
Reynaldo J Quintana
Soonho Song
Alejandro C Zaffaroni
Joshua D Rabinowitz
Original Assignee
Alexza Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexza Pharmaceuticals Inc filed Critical Alexza Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2052753T3 publication Critical patent/DK2052753T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/60—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/047—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters by exothermic chemical reaction
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24V—COLLECTION, PRODUCTION OR USE OF HEAT NOT OTHERWISE PROVIDED FOR
    • F24V30/00—Apparatus or devices using heat produced by exothermal chemical reactions other than combustion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8268—Fuel storage cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catching Or Destruction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)

Claims (14)

1. Fremgangsmåde til fordampning af et lægemiddel (15), omfattende: at tilvejebringe et hus (30) med et midterområde og et mundstykke (34) kendetegnet ved, at den omfatter: et substrat (20) inden i huset (30), som har en inderflade (20a), der omgiver et indre område, og en yderflade (20b); et brændbart element (16) inden i det indre område af substratet (20); en gnist eller modstandstændingsanordning, der er forbundet med det brændbare element (16), til antænding af forbrændingen af det brændbare element (16); og et medikament (15) på yderfladen (20b) af substratet (20), eller imprægneret i substratet (20), hvor lægemidlet skal fordampes efter antænding af det brændbare element (16) og; påbegyndelse af en eksoterm reaktion inden i det indre område af substratet (20), hvor yderfladen (20b) af substratet (20) opvarmes hurtigt og lægemidlet (15) fordampes ind i husets (30) midterområde (30).
2. Fremgangsmåde ifølge krav 1, hvor det brændbare element (16) forsegles i en kolbe (14).
3. Fremgangsmåde ifølge krav 2, hvor kolben (14) er fremstillet af glas.
4. Fremgangsmåde ifølge krav 3, hvor kolben (14) udgør inder- og yderfladen af substratet (20).
5. Fremgangsmåde ifølge krav 1, hvor substratet (20) er metallisk.
6. Fremgangsmåde ifølge krav 5, hvor substratet (20) er fremstillet af rustfrit stål eller aluminium.
7. Fremgangsmåde ifølge krav 1, hvor det brændbare element (16) forbruger gas efter forbrænding.
8. Fremgangsmåde ifølge krav 7, hvor det brændbare element (15) omfatter et brændbart metal, fortrinsvis udvalgt blandt magnesium, zirkonium og aluminium.
9. Fremgangsmåde ifølge krav 2, hvor substratet (20) er coatet på den forseglede kolbe (14).
10. Fremgangsmåde ifølge krav 1, hvor tændingsanordningen omfatter en strømkilde (40) til antænding af det brændbare element (16), og hvor anordningen kan deles i to sektioner, en første sektion (30a), der rummer strømkilden (40), og den anden sektion (30b), der rummer substratet (20), brændbart element (16) og lægemiddel (15).
11. Fremgangsmåde ifølge krav 1, hvor fremgangsmåden omfatter, efter at lægemidlet er fordampet, et trin, hvor dampen afkøles og dampen kondenseres for at tilvejebringe en aerosol.
12. Fremgangsmåde ifølge et af de foregående krav, hvor lægemidlet (15) foreligger i form af en ren aktiv forbindelse.
13. Fremgangsmåde ifølge et af kravene 1 til 12, hvor lægemidlet (15) foreligger i form af en blanding af aktiv(e) forbindelse(r) og farmaceutisk accep-tabelt/acceptable hjælpestof(fer), og hvor det/de farmaceutisk acceptable hjælpestof(fer) er flygtigt eller ikke-flygtigt.
14. Fremgangsmåde ifølge krav 11, hvor lægemidlet omfatter apomorfin.
DK09002094.2T 2002-05-13 2003-05-13 Fremgangsmåde til fordampning af en forbindelse DK2052753T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/146,086 US7458374B2 (en) 2002-05-13 2002-05-13 Method and apparatus for vaporizing a compound
EP03734014A EP1506031B1 (en) 2002-05-13 2003-05-13 Method and apparatus for vaporizing a compound

Publications (1)

Publication Number Publication Date
DK2052753T3 true DK2052753T3 (da) 2017-04-24

Family

ID=29400465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09002094.2T DK2052753T3 (da) 2002-05-13 2003-05-13 Fremgangsmåde til fordampning af en forbindelse

Country Status (16)

Country Link
US (2) US7458374B2 (da)
EP (3) EP2052753B1 (da)
JP (1) JP4426439B2 (da)
CN (2) CN101623528B (da)
AT (1) ATE425784T1 (da)
CA (1) CA2485721C (da)
CY (1) CY1118820T1 (da)
DE (1) DE60326713D1 (da)
DK (1) DK2052753T3 (da)
ES (2) ES2323418T3 (da)
HK (1) HK1243014A1 (da)
IL (1) IL165161A0 (da)
MX (1) MXPA04011279A (da)
PT (1) PT2052753T (da)
SI (1) SI2052753T1 (da)
WO (1) WO2003095012A1 (da)

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