DK0869949T3 - Benzoxaziner som antimikrobielle midler - Google Patents

Benzoxaziner som antimikrobielle midler

Info

Publication number: DK0869949T3
Authority: DK; Denmark
Prior art keywords: benzoxazines; antimicrobial agents; antimicrobial; agents
Prior art date: 1995-11-07

Application number

DK96936648T

Other languages

Danish (da)

English (en)

Inventor

Roger Frechette

Michele A Weidner-Wells

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-07

Filing date

1996-10-17

Publication date

2003-03-31

1996-10-17 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2003-03-31 Application granted granted Critical

2003-03-31 Publication of DK0869949T3 publication Critical patent/DK0869949T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK96936648T 1995-11-07 1996-10-17 Benzoxaziner som antimikrobielle midler DK0869949T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/553,188 US5696117A (en)	1995-11-07	1995-11-07	Benzoxazine antimicrobial agents
PCT/US1996/016669 WO1997017333A1 (fr)	1995-11-07	1996-10-17	Agents antimicrobiens a base de benzoxazine

Publications (1)

Publication Number	Publication Date
DK0869949T3 true DK0869949T3 (da)	2003-03-31

Family

ID=24208465

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96936648T DK0869949T3 (da)	1995-11-07	1996-10-17	Benzoxaziner som antimikrobielle midler

Country Status (24)

Country	Link
US (2)	US5696117A (fr)
EP (1)	EP0869949B1 (fr)
JP (1)	JP2000500134A (fr)
KR (1)	KR100503910B1 (fr)
AR (1)	AR004706A1 (fr)
AT (1)	ATE229944T1 (fr)
AU (1)	AU720743B2 (fr)
BR (1)	BR9611400A (fr)
CZ (1)	CZ137998A3 (fr)
DE (1)	DE69625515T2 (fr)
DK (1)	DK0869949T3 (fr)
ES (1)	ES2188795T3 (fr)
HU (1)	HUP9901184A3 (fr)
IL (1)	IL124337A (fr)
MX (1)	MX9803650A (fr)
MY (1)	MY128650A (fr)
NO (1)	NO311026B1 (fr)
NZ (1)	NZ321251A (fr)
PL (1)	PL189987B1 (fr)
RU (1)	RU2191179C2 (fr)
SK (2)	SK285388B6 (fr)
TW (1)	TW536537B (fr)
WO (1)	WO1997017333A1 (fr)
ZA (1)	ZA969326B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6265401B1 (en) *	1997-10-27	2001-07-24	Reddy-Cheminor, Inc.	Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
CA2307068C (fr)	1997-10-27	2007-04-10	Dr. Reddy's Research Foundation	Composes bicycliques, procede de preparation et compositions pharmaceutiques les contenant
AU3406599A (en) *	1998-04-09	1999-11-01	Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin	Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis
US6667299B1 (en) *	2000-03-16	2003-12-23	Hollis-Eden Pharmaceuticals, Inc.	Pharmaceutical compositions and treatment methods
AU6762400A (en) *	1999-08-12	2001-03-13	Cor Therapeutics, Inc.	Inhibitors of factor xa
US6908908B2 (en) *	2000-05-12	2005-06-21	Ortho-Mcneil Pharmaceutical, Inc.	Biologically active 4H-benzo [1,4] oxazin-3-ones
EP1280783A2 (fr) *	2000-05-12	2003-02-05	Ortho-McNeil Pharmaceutical, Inc.	Methodes de traitement mettant en oeuvre des benzoxazinones comme modulateurs du recepteur gamma active par le proliferateur du peroxisome
AU2001259747A1 (en) *	2000-05-12	2001-11-26	Ortho-Mcneil Pharmaceutical, Inc.	Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment
ES2288957T3 (es) *	2000-05-12	2008-02-01	Ortho-Mcneil Pharmaceutical, Inc.	4h-benzo(1.4)oxazin-3-ina biologicamente activas.
JP4202250B2 (ja)	2001-07-25	2008-12-24	バイオマリンファーマシューティカルインコーポレイテッド	血液脳関門輸送を調節するための組成物および方法
CA2537355C (fr) *	2003-09-01	2012-10-09	Ono Pharmaceutical Co., Ltd.	Compose cyclique condense et son utilisation
AU2004274324B2 (en) *	2003-09-17	2009-11-05	Ono Pharmaceutical Co., Ltd.	Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient
US20050266575A1 (en) *	2004-05-27	2005-12-01	Mayo Kevin H	Pharmacophores for nociceptin, methods of obtaining and using in screening for nociceptin mimics
GB0423405D0 (en) *	2004-10-21	2004-11-24	Novartis Ag	Organic compounds
WO2006082495A1 (fr) *	2005-02-02	2006-08-10	Ranbaxy Laboratories Limited	Modulateurs des recepteurs actives par les proliferateurs de peroxysomes
EP3827747A1 (fr)	2005-04-28	2021-06-02	Otsuka Pharmaceutical Co., Ltd.	Système pharma-informatique
AU2006317457B2 (en) *	2005-11-24	2011-09-08	Eisai R & D Management Co., Ltd.	Morpholine type cinnamide compound
EP1985297A1 (fr) *	2006-01-27	2008-10-29	Japan Tobacco, Inc.	Acide carboxylique et applications
US20070197512A1 (en) *	2006-01-27	2007-08-23	Japan Tobacco Inc.	Carboxylic Acid Compounds and Use Thereof
TWI385161B (zh)	2006-02-02	2013-02-11	Mitsubishi Tanabe Pharma Corp	含氮雜雙環化合物
JP5099814B2 (ja) *	2006-02-02	2012-12-19	田辺三菱製薬株式会社	含窒素複素二環式化合物
EP1994928A4 (fr) *	2006-03-10	2010-08-11	Yuuzou Tsuchida	Agent antimicrobien et composition antimicrobienne
CN101594878A (zh)	2006-09-18	2009-12-02	雷普特药品公司	通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
TWI410410B (zh)	2007-08-10	2013-10-01	Ono Pharmaceutical Co	Phenylacetic acid compounds
DK3395372T3 (da)	2009-02-20	2022-04-19	Enhanx Biopharm Inc	System til afgivelse af glutathion-baseret medikament
EP2420493A4 (fr) *	2009-04-14	2012-09-05	Nissan Chemical Ind Ltd	Dérivés d'haloalkylsulfonanilide
CN110075069A (zh)	2009-05-06	2019-08-02	实验室护肤股份有限公司	包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
US8669363B2 (en)	2011-03-24	2014-03-11	Southern Methodist University	Quinoxaline compounds and derivatives
US9493452B2 (en)	2011-03-24	2016-11-15	Southern Methodist University	Compounds and derivatives of 2H-pyrido (3,2-b)(1, 4) oxazin 3)4H)-ones as raf kinase and LRRK2 inhibitors
WO2013142831A1 (fr)	2012-03-23	2013-09-26	Southern Methodist University	Procédés permettant de fabriquer et d'utiliser des dérivés de thioxothiazolidine et de rhodanine en tant qu'inhibiteurs de vih-1 et de jsp-1
GB2533925A (en) *	2014-12-31	2016-07-13	Univ Bath	Antimicrobial compounds, compositions and methods
JP7397491B2 (ja) *	2018-10-23	2023-12-13	国立研究開発法人科学技術振興機構	ＰＰＡＲδ活性化剤

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3635956A (en) *	1968-03-01	1972-01-18	Squibb & Sons Inc	Benzothiazines related compounds derivatives and salts thereof
US3725403A (en) *	1970-10-20	1973-04-03	Squibb & Sons Inc	Benzothiazine derivatives
JPS5547006B2 (fr) *	1973-04-04	1980-11-27
FR2588868B1 (fr) *	1985-10-21	1988-11-10	Negma Laboratoires	Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
EP0233728A1 (fr) *	1986-02-11	1987-08-26	Takeda Chemical Industries, Ltd.	Dérivés de 1,4-benzoxazine, leur préparation et leur application
DE3705621C2 (de) *	1986-02-25	1997-01-09	Otsuka Pharma Co Ltd	Heterocyclisch substituierte Chinoloncarbonsäurederivate
AU5404790A (en) *	1989-04-26	1990-11-16	Upjohn Company, The	Antibacterial pyrido(1,2,3-de)-1,4-benzoxazinone agents
FI96313C (fi) *	1990-11-28	1996-06-10	Daiichi Seiyaku Co	Menetelmä terapeuttisesti käyttökelpoisten ja optisesti aktiivisten 10-(3-amino-4,4-dialkyyli-1-pyrrolidinyyli)-9-fluori-2,3-dihydro-3(S)-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojen valmistamiseksi
DE4304806A1 (de) *	1993-02-17	1994-08-18	Kali Chemie Pharma Gmbh	5-Phenyl-pyrrolo-1,4-benzoxazin- und -thiazin-Derivate sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2714381B1 (fr) *	1993-12-29	1996-02-02	Pharmascience Lab	Dérivés de la benzoxazine, leurs procédés d'obtention et leur utilisation en tant que médicaments .

1995
- 1995-11-07 US US08/553,188 patent/US5696117A/en not_active Expired - Lifetime
1996
- 1996-10-17 JP JP9518188A patent/JP2000500134A/ja not_active Ceased
- 1996-10-17 AT AT96936648T patent/ATE229944T1/de not_active IP Right Cessation
- 1996-10-17 NZ NZ321251A patent/NZ321251A/en unknown
- 1996-10-17 HU HU9901184A patent/HUP9901184A3/hu unknown
- 1996-10-17 IL IL12433796A patent/IL124337A/en not_active IP Right Cessation
- 1996-10-17 SK SK1033-2002A patent/SK285388B6/sk not_active IP Right Cessation
- 1996-10-17 KR KR10-1998-0703405A patent/KR100503910B1/ko not_active Expired - Fee Related
- 1996-10-17 EP EP96936648A patent/EP0869949B1/fr not_active Expired - Lifetime
- 1996-10-17 RU RU98110572/04A patent/RU2191179C2/ru not_active IP Right Cessation
- 1996-10-17 DE DE69625515T patent/DE69625515T2/de not_active Expired - Fee Related
- 1996-10-17 CZ CZ981379A patent/CZ137998A3/cs unknown
- 1996-10-17 PL PL96326704A patent/PL189987B1/pl not_active IP Right Cessation
- 1996-10-17 SK SK597-98A patent/SK283888B6/sk not_active IP Right Cessation
- 1996-10-17 AU AU74519/96A patent/AU720743B2/en not_active Ceased
- 1996-10-17 WO PCT/US1996/016669 patent/WO1997017333A1/fr not_active Ceased
- 1996-10-17 DK DK96936648T patent/DK0869949T3/da active
- 1996-10-17 ES ES96936648T patent/ES2188795T3/es not_active Expired - Lifetime
- 1996-10-17 BR BR9611400-2A patent/BR9611400A/pt not_active IP Right Cessation
- 1996-11-06 AR ARP960105075A patent/AR004706A1/es active IP Right Grant
- 1996-11-06 ZA ZA9609326A patent/ZA969326B/xx unknown
- 1996-11-07 MY MYPI96004648A patent/MY128650A/en unknown
- 1996-11-25 TW TW085114485A patent/TW536537B/zh not_active IP Right Cessation
1997
- 1997-07-23 US US08/899,235 patent/US5854242A/en not_active Expired - Lifetime
1998
- 1998-05-06 NO NO19982071A patent/NO311026B1/no not_active IP Right Cessation
- 1998-05-07 MX MX9803650A patent/MX9803650A/es not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO982071L (no)	1998-06-05
RU2191179C2 (ru)	2002-10-20
PL189987B1 (pl)	2005-10-31
ATE229944T1 (de)	2003-01-15
NO311026B1 (no)	2001-10-01
US5696117A (en)	1997-12-09
NO982071D0 (no)	1998-05-06
MX9803650A (es)	1998-11-30
US5854242A (en)	1998-12-29
AU720743B2 (en)	2000-06-08
SK59798A3 (en)	1999-09-10
IL124337A0 (en)	1998-12-06
PL326704A1 (en)	1998-10-26
SK283888B6 (sk)	2004-04-06
DE69625515T2 (de)	2003-05-15
DE69625515D1 (de)	2003-01-30
HUP9901184A3 (en)	2001-11-28
EP0869949A1 (fr)	1998-10-14
AU7451996A (en)	1997-05-29
NZ321251A (en)	1999-10-28
ZA969326B (en)	1998-05-06
HUP9901184A2 (hu)	1999-10-28
JP2000500134A (ja)	2000-01-11
IL124337A (en)	2001-08-08
SK285388B6 (sk)	2006-12-07
KR19990067395A (ko)	1999-08-16
MY128650A (en)	2007-02-28
CZ137998A3 (cs)	1998-10-14
ES2188795T3 (es)	2003-07-01
WO1997017333A1 (fr)	1997-05-15
EP0869949B1 (fr)	2002-12-18
BR9611400A (pt)	1999-08-31
KR100503910B1 (ko)	2005-12-29
TW536537B (en)	2003-06-11
AR004706A1 (es)	1999-03-10

Publication	Publication Date	Title
DK0869949T3 (da)	2003-03-31	Benzoxaziner som antimikrobielle midler
DK1930330T3 (da)	2011-12-12	Pleuromutilinderivater som antimikrobielle midler
NO20011738D0 (no)	2001-04-06	Heterocyclylaminometyloksazolidinoner som antibakterielle midler
BR9609387A (pt)	1999-05-18	Composições herbicidas
NO985643D0 (no)	1998-12-03	Antimikrobielle blandinger
FI971516L (fi)	1997-04-11	Antimikrobinen koostumus
NO984106D0 (no)	1998-09-07	Azolobenzazepin-derivater som neurologisk aktive midler
DE69626556D1 (de)	2003-04-17	Biozide Zusammensetzungen
PT831697E (pt)	2002-07-31	Composicoes microbicidas
DK0975623T3 (da)	2002-10-14	Indazolamidforbindelser som sertoninerge midler
NO985644D0 (no)	1998-12-03	Antimikrobielle midler som orale hygieneprodukter
DK0531548T3 (da)	1995-11-27	Carbostyril-forbindelser som anti-thrombotiske midler
NO991384D0 (no)	1999-03-22	Substituerte heterocykler som anti-tumormidler
BR9607925A (pt)	1998-06-09	Composição fungicida
BR9609615A (pt)	1999-05-25	Composição herbicida seletiva
ATE192019T1 (de)	2000-05-15	Herbizide zusammensetzungen
EP0961615A4 (fr)	2002-09-11	Agent antimicrobien
DK1011689T3 (da)	2007-05-21	Anvendelse af 9a-azalider som veterinære antimikrobielle midler
DE69605988D1 (de)	2000-02-10	Synergistische antimikrobielle Zusammensetzung
DE69603260D1 (de)	1999-08-19	Gemischte herbizide zusammensetzungen
NO980595D0 (no)	1998-02-11	Biocidale sammensetninger
TR199801835A3 (tr)	1999-04-21	Antimikrobiyal kompozisyonlar.
DK0828715T3 (da)	2001-10-08	N-Oxider som antibakterielle midler
NO965109D0 (no)	1996-11-29	Antimikrobielle sammensetninger
DK0770603T3 (da)	1999-06-14	Alkynylphenylaminosulfonylurinstoffer som herbicider