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CY1117778T1 - Βελτιωμενη ανασυνδυασμενη ανθρωπινη ωοθυλακιοτροπο ορμονη - Google Patents

Βελτιωμενη ανασυνδυασμενη ανθρωπινη ωοθυλακιοτροπο ορμονη

Info

Publication number
CY1117778T1
CY1117778T1 CY20161100539T CY161100539T CY1117778T1 CY 1117778 T1 CY1117778 T1 CY 1117778T1 CY 20161100539 T CY20161100539 T CY 20161100539T CY 161100539 T CY161100539 T CY 161100539T CY 1117778 T1 CY1117778 T1 CY 1117778T1
Authority
CY
Cyprus
Prior art keywords
improved
oxyphological
hormony
fsh
recommended human
Prior art date
Application number
CY20161100539T
Other languages
English (en)
Inventor
Steffen Goletz
Lars Stöckl
Original Assignee
Glycotope Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43242604&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1117778(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glycotope Gmbh filed Critical Glycotope Gmbh
Publication of CY1117778T1 publication Critical patent/CY1117778T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται στα βελτιωμένα παρασκευάσματα FSH τα οποία είναι ικανά να διεγείρουν την απελευθέρωση των στεροειδών φύλου σε πολύ χαμηλότερη συγκέντρωση από τα ουρικά προϊόντα FSH που χρησιμοποιούνται συνήθως ή την ανασυνδυασμένη FSH που λαμβάνεται από τα κύτταρα CHO και δρα ανεξάρτητα της σηματοδότησης cAMP. Αυτά τα βελτιωμένα παρασκευάσματα FSH μπορούν να χρησιμοποιηθούν για τη θεραπεία της στειρότητας.
CY20161100539T 2010-08-04 2016-06-16 Βελτιωμενη ανασυνδυασμενη ανθρωπινη ωοθυλακιοτροπο ορμονη CY1117778T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2010/004769 WO2012016576A1 (en) 2010-08-04 2010-08-04 Improved recombinant human follicle-stimulating hormone
PCT/EP2011/063492 WO2012017058A1 (en) 2010-08-04 2011-08-04 Improved recombinant human follicle-stimulating hormone
EP11757190.1A EP2601210B1 (en) 2010-08-04 2011-08-04 Improved recombinant human follicle-stimulating hormone

Publications (1)

Publication Number Publication Date
CY1117778T1 true CY1117778T1 (el) 2017-05-17

Family

ID=43242604

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100539T CY1117778T1 (el) 2010-08-04 2016-06-16 Βελτιωμενη ανασυνδυασμενη ανθρωπινη ωοθυλακιοτροπο ορμονη

Country Status (27)

Country Link
US (1) US9527899B2 (el)
EP (2) EP2601210B1 (el)
JP (2) JP6001534B2 (el)
KR (1) KR20130136448A (el)
CN (2) CN106146646A (el)
AR (1) AR082852A1 (el)
AU (1) AU2011287525B2 (el)
BR (1) BR112013004051A2 (el)
CA (1) CA2805134C (el)
CU (1) CU24043B1 (el)
CY (1) CY1117778T1 (el)
DK (1) DK2601210T3 (el)
EA (1) EA029955B1 (el)
ES (2) ES2576868T3 (el)
HR (1) HRP20160671T1 (el)
HU (1) HUE028357T2 (el)
IL (1) IL223867B (el)
MX (1) MX336489B (el)
NZ (1) NZ604877A (el)
PL (1) PL2601210T3 (el)
PT (1) PT2601210T (el)
RS (1) RS54905B1 (el)
SG (1) SG186755A1 (el)
SI (1) SI2601210T1 (el)
SM (1) SMT201600219B (el)
WO (2) WO2012016576A1 (el)
ZA (1) ZA201209436B (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI488640B (zh) * 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
WO2012016576A1 (en) 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
WO2012168680A1 (en) 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
NZ707016A (en) * 2012-07-30 2017-08-25 Trophogen Inc Glycoprotein hormone long-acting superagonists
CN104543416B (zh) * 2013-10-09 2018-06-19 中国科学院大连化学物理研究所 一种调节雌性动物繁殖性能的功能性单糖饲料及其应用
CN103740754B (zh) * 2013-10-25 2015-06-24 中国食品药品检定研究院 含有鼠神经生长因子的表达载体及细胞
SG11201608132UA (en) 2014-04-18 2016-11-29 Glycotope Gmbh Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone
EP3091033A1 (en) * 2015-05-06 2016-11-09 Gamamabs Pharma Anti-human-her3 antibodies and uses thereof
AR105669A1 (es) * 2015-08-10 2017-10-25 Glycotope Gmbh Factor vii recombinante mejorado
US20180264086A1 (en) * 2015-09-17 2018-09-20 Glycotope Gmbh Mammalian follicle-stimulating hormone composition with increased stability
CN106053861A (zh) * 2016-07-28 2016-10-26 高常青 一种卵泡刺激素生物活性强度检测方法
CA3160345A1 (en) * 2019-11-06 2021-05-14 The Regents Of The University Of Colorado, A Body Corporate Modified follicle-stimulating hormone and methods of using the same
CN116063490A (zh) * 2021-09-07 2023-05-05 苏州晟济药业有限公司 一种vhh抗体或其抗原片段的突变体及其用途
EP4519296A1 (en) * 2022-05-06 2025-03-12 The Regents of the University of Colorado, a body corporate Modified follicle-stimulating hormone and methods of using the same
IT202200023031A1 (it) * 2022-11-08 2024-05-08 Oncogreen Therapeutics S A Composto ad effetto anti-metastatico
IT202200023037A1 (it) * 2022-11-08 2024-05-08 Oncogreen Therapeutics S A Composti per l’uso nella riprogrammazione dei macrofagi

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1176976T2 (sl) 1999-05-07 2015-12-31 Merck Serono Sa Uporaba LH, dajanega v srednji ali pozni folikularni fazi, za zdravljenje anovulatornih žensk
MEP38608A (en) * 2001-10-22 2011-02-10 Merck Serono Sa Gonadotrophins for folliculogenesis
EP1725673A1 (en) * 2004-02-13 2006-11-29 Glycotope Gmbh Sialytated glycoproteins-process conditions and an efficient method for their production
ES2620261T3 (es) * 2006-09-10 2017-06-28 Glycotope Gmbh Uso de células humanas de origen leucémico mieloide para expresión de anticuerpos
GB2459641B (en) * 2008-04-16 2012-06-27 Ubiquisys Ltd Basestation power control
TWI488640B (zh) * 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone

Also Published As

Publication number Publication date
EA201390194A1 (ru) 2013-06-28
US9527899B2 (en) 2016-12-27
ES2576868T3 (es) 2016-07-11
RS54905B1 (sr) 2016-10-31
SG186755A1 (en) 2013-02-28
US20130137636A1 (en) 2013-05-30
BR112013004051A2 (pt) 2016-07-05
CN103068839A (zh) 2013-04-24
EP3075744B1 (en) 2019-12-18
HUE028357T2 (en) 2016-12-28
SMT201600219B (it) 2016-08-31
IL223867B (en) 2018-04-30
HRP20160671T1 (hr) 2016-09-23
EA029955B1 (ru) 2018-06-29
CN103068839B (zh) 2016-06-22
SI2601210T1 (sl) 2016-09-30
EP3075744A1 (en) 2016-10-05
WO2012017058A1 (en) 2012-02-09
WO2012017058A8 (en) 2016-04-07
CN106146646A (zh) 2016-11-23
AR082852A1 (es) 2013-01-16
NZ604877A (en) 2014-09-26
CA2805134A1 (en) 2012-02-09
MX336489B (es) 2016-01-21
CA2805134C (en) 2020-01-28
JP2016168055A (ja) 2016-09-23
EP2601210A1 (en) 2013-06-12
EP2601210B1 (en) 2016-05-11
ES2764083T3 (es) 2020-06-02
CU24043B1 (es) 2014-11-27
MX2013000500A (es) 2013-02-21
DK2601210T3 (en) 2016-07-04
PL2601210T3 (pl) 2016-11-30
JP6001534B2 (ja) 2016-10-05
PT2601210T (pt) 2016-07-07
ZA201209436B (en) 2014-02-26
CU20130019A7 (es) 2013-05-31
AU2011287525A1 (en) 2013-01-17
JP2013535481A (ja) 2013-09-12
AU2011287525B2 (en) 2014-09-25
KR20130136448A (ko) 2013-12-12
WO2012016576A1 (en) 2012-02-09

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